Igor B Zhulin

Summary

Affiliation: Georgia Institute of Technology
Country: USA

Publications

  1. ncbi request reprint The superfamily of chemotaxis transducers: from physiology to genomics and back
    I B Zhulin
    School of Biology, Georgia Institute of Technology, 310 Ferst Drive, Atlanta, GA 30332 0230, USA
    Adv Microb Physiol 45:157-98. 2001
  2. pmc Digging with experimental pick and computational shovel: a new addition to the histidine kinase superfamily
    Igor B Zhulin
    School of Biology, Georgia Institute of Technology, Atlanta, Georgia 30332 0230, USA
    J Bacteriol 186:267-9. 2004
  3. pmc Common extracellular sensory domains in transmembrane receptors for diverse signal transduction pathways in bacteria and archaea
    Igor B Zhulin
    School of Biology, Georgia Institute of Technology, Atlanta, GA 30332 0230, USA
    J Bacteriol 185:285-94. 2003
  4. pmc Comparative genomic and protein sequence analyses of a complex system controlling bacterial chemotaxis
    Kristin Wuichet
    School of Biology, Georgia Institute of Technology, Atlanta, Georgia, USA
    Methods Enzymol 422:1-31. 2007
  5. pmc Evolutionary genomics reveals conserved structural determinants of signaling and adaptation in microbial chemoreceptors
    Roger P Alexander
    Center for Bioinformatics and Computational Biology, School of Biology, Georgia Institute of Technology, Atlanta, GA 30332 0230, USA
    Proc Natl Acad Sci U S A 104:2885-90. 2007
  6. ncbi request reprint Molecular evolution of sensory domains in cyanobacterial chemoreceptors
    Kristin Wuichet
    School of Biology, Georgia Institute of Technology, Atlanta, GA 30332 0230, USA
    Trends Microbiol 11:200-3. 2003
  7. ncbi request reprint Four-helix bundle: a ubiquitous sensory module in prokaryotic signal transduction
    Luke E Ulrich
    Center for Bioinformatics and Computational Biology, School of Biology, Georgia Institute of Technology Atlanta, GA 30332 0230 USA
    Bioinformatics 21:iii45-8. 2005
  8. pmc One-component systems dominate signal transduction in prokaryotes
    Luke E Ulrich
    Center for Bioinformatics and Computational Biology, School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA
    Trends Microbiol 13:52-6. 2005
  9. ncbi request reprint The NIT domain: a predicted nitrate-responsive module in bacterial sensory receptors
    Chengyi J Shu
    School of Biology, Georgia Institute of Technology, Atlanta, GA 30332 0230, USA
    Trends Biochem Sci 28:121-4. 2003
  10. pmc Different evolutionary constraints on chemotaxis proteins CheW and CheY revealed by heterologous expression studies and protein sequence analysis
    Gladys Alexandre
    School of Biology, Georgia Institute of Technology, Atlanta 30332 0230, USA
    J Bacteriol 185:544-52. 2003

Collaborators

Detail Information

Publications21

  1. ncbi request reprint The superfamily of chemotaxis transducers: from physiology to genomics and back
    I B Zhulin
    School of Biology, Georgia Institute of Technology, 310 Ferst Drive, Atlanta, GA 30332 0230, USA
    Adv Microb Physiol 45:157-98. 2001
    ..This indicates that basic principles of sensory transduction are conserved throughout the phylogenetic tree and that the chemotaxis transducer superfamily is a valuable source of novel sensory elements yet to be discovered...
  2. pmc Digging with experimental pick and computational shovel: a new addition to the histidine kinase superfamily
    Igor B Zhulin
    School of Biology, Georgia Institute of Technology, Atlanta, Georgia 30332 0230, USA
    J Bacteriol 186:267-9. 2004
  3. pmc Common extracellular sensory domains in transmembrane receptors for diverse signal transduction pathways in bacteria and archaea
    Igor B Zhulin
    School of Biology, Georgia Institute of Technology, Atlanta, GA 30332 0230, USA
    J Bacteriol 185:285-94. 2003
    ..The variety of signaling pathways using the CHASE-type domains indicates that these domains sense some critically important extracellular signals...
  4. pmc Comparative genomic and protein sequence analyses of a complex system controlling bacterial chemotaxis
    Kristin Wuichet
    School of Biology, Georgia Institute of Technology, Atlanta, Georgia, USA
    Methods Enzymol 422:1-31. 2007
    ....
  5. pmc Evolutionary genomics reveals conserved structural determinants of signaling and adaptation in microbial chemoreceptors
    Roger P Alexander
    Center for Bioinformatics and Computational Biology, School of Biology, Georgia Institute of Technology, Atlanta, GA 30332 0230, USA
    Proc Natl Acad Sci U S A 104:2885-90. 2007
    ....
  6. ncbi request reprint Molecular evolution of sensory domains in cyanobacterial chemoreceptors
    Kristin Wuichet
    School of Biology, Georgia Institute of Technology, Atlanta, GA 30332 0230, USA
    Trends Microbiol 11:200-3. 2003
    ..This fact could explain a remarkable diversity of the sensing repertoire of chemotaxis receptors in microorganisms...
  7. ncbi request reprint Four-helix bundle: a ubiquitous sensory module in prokaryotic signal transduction
    Luke E Ulrich
    Center for Bioinformatics and Computational Biology, School of Biology, Georgia Institute of Technology Atlanta, GA 30332 0230 USA
    Bioinformatics 21:iii45-8. 2005
    ..Current domain models for this important sensory module are inaccurate and, therefore, cannot reveal the distribution of this domain within the current genomic landscape...
  8. pmc One-component systems dominate signal transduction in prokaryotes
    Luke E Ulrich
    Center for Bioinformatics and Computational Biology, School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA
    Trends Microbiol 13:52-6. 2005
    ..One-component systems are evolutionarily older, more widely distributed among bacteria and archaea, and display a greater diversity of domains than two-component systems...
  9. ncbi request reprint The NIT domain: a predicted nitrate-responsive module in bacterial sensory receptors
    Chengyi J Shu
    School of Biology, Georgia Institute of Technology, Atlanta, GA 30332 0230, USA
    Trends Biochem Sci 28:121-4. 2003
    ....
  10. pmc Different evolutionary constraints on chemotaxis proteins CheW and CheY revealed by heterologous expression studies and protein sequence analysis
    Gladys Alexandre
    School of Biology, Georgia Institute of Technology, Atlanta 30332 0230, USA
    J Bacteriol 185:544-52. 2003
    ..Our findings suggest that proteins from the same cellular pathway encoded by genes from the same operon have different evolutionary constraints on their structures that reflect differences in their functions...
  11. ncbi request reprint Ecological role of energy taxis in microorganisms
    Gladys Alexandre
    Department of Biology, Georgia State University, Atlanta, GA 30303, USA
    FEMS Microbiol Rev 28:113-26. 2004
    ..Such knowledge is critical to a better understanding of the ecological role of energy taxis...
  12. doi request reprint SeqDepot: streamlined database of biological sequences and precomputed features
    Luke E Ulrich
    Agile Genomics, LLC, Mount Pleasant, SC 29466, USA, Department of Microbiology, University of Tennessee, Knoxville, TN 37996, USA and Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA
    Bioinformatics 30:295-7. 2014
    ..We have also developed an HTML5/JavaScript web application exemplifying how to interact with SeqDepot and Perl/Python scripts for use with local processing pipelines...
  13. ncbi request reprint ANTAR: an RNA-binding domain in transcription antitermination regulatory proteins
    Chengyi J Shu
    School of Biology, Georgia Institute of Technology, Atlanta, GA 30332 0230, USA
    Trends Biochem Sci 27:3-5. 2002
    ..Transcription antitermination appears to be a common mechanism for controlling gene expression by this family of regulators...
  14. ncbi request reprint CHASE: an extracellular sensing domain common to transmembrane receptors from prokaryotes, lower eukaryotes and plants
    C Mougel
    School of Biology, Georgia Institute of Technology, Atlanta, GA 30332-0230, USA
    Trends Biochem Sci 26:582-4. 2001
    ..The CHASE domain is predicted to sense stimuli that are specific for the developmental program of an organism...
  15. ncbi request reprint Aer and Tsr guide Escherichia coli in spatial gradients of oxidizable substrates
    Suzanne E Greer-Phillips
    Department of Biochemistry and Microbiology, Division of Microbiology and Molecular Genetics, School of Medicine, Loma Linda University, Loma Linda, CA 92350, USA
    Microbiology 149:2661-7. 2003
    ..Taken together, the results demonstrate that Aer and Tsr mediate responses to a broad range of chemicals and their attractant repertoires overlap with those of specialized chemoreceptors, namely Trg (ribose, galactose) and Tar (maltose)...
  16. ncbi request reprint Dual recognition of the bacterial chemoreceptor by chemotaxis-specific domains of the CheR methyltransferase
    Daisuke Shiomi
    Division of Biological Science, Graduate School of Science, Nagoya University, Chikusa ku, Japan
    J Biol Chem 277:42325-33. 2002
    ..Thus, the two chemotaxis-specific modules of CheR interact with distinct regions of the chemoreceptor for targeting to the receptor cluster and for recognition of the substrate sites, respectively...
  17. pmc Bacterial signaling and motility: sure bets
    Robert Belas
    Center of Marine Biotechnology, University of Maryland Biotechnology Institute, 701 East Pratt Street, Baltimore, MD 21202, USA
    J Bacteriol 190:1849-56. 2008
  18. pmc MiST: a microbial signal transduction database
    Luke E Ulrich
    Joint Institute for Computational Sciences, The University of Tennessee Oak Ridge National Laboratory, Oak Ridge, TN 37831 6173, USA
    Nucleic Acids Res 35:D386-90. 2007
    ..Newly available, complete genomes are loaded into the database each month. MiST is the only comprehensive and up-to-date electronic catalog of the signaling machinery in microbial genomes...
  19. pmc Genome sequence of Thermofilum pendens reveals an exceptional loss of biosynthetic pathways without genome reduction
    Iain Anderson
    Joint Genome Institute, 2800 Mitchell Dr, Walnut Creek, CA 94598, USA
    J Bacteriol 190:2957-65. 2008
    ....
  20. pmc Complete genome sequence of the complex carbohydrate-degrading marine bacterium, Saccharophagus degradans strain 2-40 T
    Ronald M Weiner
    Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, USA
    PLoS Genet 4:e1000087. 2008
    ..This is the first sequenced genome of a marine bacterium that can degrade plant cell walls, an important component of the carbon cycle that is not well-characterized in the marine environment...
  21. ncbi request reprint A major chemotaxis gene cluster in Azospirillum brasilense and relationships between chemotaxis operons in alpha-proteobacteria
    Dieter Hauwaerts
    Centre of Microbial and Plant Genetics, Katholieke Universiteit Leuven, B 3001, Heverlee, Belgium
    FEMS Microbiol Lett 208:61-7. 2002
    ..brasilense operon to one of them. Interestingly, operons that are shown to be major regulators of behavior in several alpha-proteobacterial species are not orthologous...