Research Topics
| Lee S KatzSummaryAffiliation: Georgia Institute of Technology Country: USA Publications
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Detail Information
Publications
Meningococcus genome informatics platform: a system for analyzing multilocus sequence typing dataLee S Katz
School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA
Nucleic Acids Res 37:W606-11. 2009....
Genomic basis of a polyagglutinating isolate of Neisseria meningitidisLavanya Rishishwar
School of Biology, Georgia Institute of Technology, Atlanta, Georgia, USA
J Bacteriol 194:5649-56. 2012..Since there is no currently available vaccine for serogroup B strains of N. meningitidis, this kind capsule-switching event could have public health relevance as a vaccine escape mutant...
Neisseria Base: a comparative genomics database for Neisseria meningitidisLee S Katz
School of Biology, Georgia Institute of Technology, USA
Database (Oxford) 2011:bar035. 2011..Using the virulent ST-11 lineage as an example, we demonstrate how this comparative genomics utility can be used to identify novel genomic markers for molecular profiling of N. meningitidis...
Haemophilus haemolyticus isolates causing clinical diseaseRaydel Anderson
Meningitis and Vaccine Preventable Disease Branch, Division of Bacterial Diseases, National Center for Infectious and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Clin Microbiol 50:2462-5. 2012..All cases had different symptoms and presentations. Our study suggests that a testing scheme that includes reliable PCR assays and standard microbiological methods should be used in order to improve H. haemolyticus identification...
Using single-nucleotide polymorphisms to discriminate disease-associated from carried genomes of Neisseria meningitidisLee S Katz
School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA
J Bacteriol 193:3633-41. 2011..A number of overrepresented functional categories related to virulence were uncovered among SNP-associated genes, including genes related to the category "symbiosis, encompassing mutualism through parasitism."..
A computational genomics pipeline for prokaryotic sequencing projectsAndrey O Kislyuk
School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA
Bioinformatics 26:1819-26. 2010..The resulting requirement to invest significant resources into custom informatics support for genome sequencing projects remains a major impediment to the accessibility of high-throughput sequence data...
Natural selection governs local, but not global, evolutionary gene coexpression networks in Caenorhabditis elegansI King Jordan
School of Biology, Georgia Institute of Technology, Atlanta, GA, USA
BMC Syst Biol 2:96. 2008..elegans mutation accumulation (MA) lines evolve essentially free from the effects of natural selection, whereas natural isolate (NI) populations are subject to selective constraints...
Comparative analysis reveals signatures of differentiation amid genomic polymorphism in Lake Malawi cichlidsYong Hwee E Loh
School of Biology, Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 315 Ferst Drive, Atlanta, Georgia 30332, USA
Genome Biol 9:R113. 2008..We report a computational and comparative analysis of these data that provides insight into the mechanisms that make closely related species different from one another...
Evaluation of new biomarker genes for differentiating Haemophilus influenzae from Haemophilus haemolyticusM Jordan Theodore
Meningitis and Vaccine Preventable Diseases Branch, Centers for Disease Control and Prevention CDC, Atlanta, Georgia, USA
J Clin Microbiol 50:1422-4. 2012..haemolyticus. Phylogenetic analysis using the 16S rRNA gene demonstrated two distinct groups for H. influenzae and H. haemolyticus...
Genome sequences for six Rhodanobacter strains, isolated from soils and the terrestrial subsurface, with variable denitrification capabilitiesJoel E Kostka
School of Biology, Georgia Institute of Technology, Atlanta, Georgia, USA
J Bacteriol 194:4461-2. 2012..The data suggest that the environmental role of bacteria from the genus Rhodanobacter should be reevaluated...
Genome sequences for five strains of the emerging pathogen Haemophilus haemolyticusI King Jordan
School of Biology, Georgia Institute of Technology, Atlanta, Georgia30333, USA
J Bacteriol 193:5879-80. 2011..Preliminary analyses indicate that these genome sequences encode markers that distinguish H. haemolyticus from its closest Haemophilus relatives and provide clues to the identity of its virulence factors...
