Gareth J FraserSummaryAffiliation: Georgia Institute of Technology Country: USA Publications
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A periodic pattern generator for dental diversityGareth J Fraser
School of Biology, Petit Institute of Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA 30332 0230, USA
BMC Biol 6:32. 2008..We address this problem through the molecular analysis of oral jaw dental diversity in Lake Malawi cichlids, where closely related species exhibit from 1 to 20 rows of teeth, with total teeth counts ranging from around 10 to 700...
An ancient gene network is co-opted for teeth on old and new jawsGareth J Fraser
Parker H Petit Institute for Bioengineering and Biosciences and School of Biology, Georgia Institute of Technology, Atlanta, Georgia, USA
PLoS Biol 7:e31. 2009..Our data highlight an amazing modularity of jaws and teeth as they coevolved during the history of vertebrates. We exploit this diversity to infer a core dental gene network, common to the first tooth and all of its descendants...
Common developmental pathways link tooth shape to regenerationGareth J Fraser
Parker H Petit Institute for Bioengineering and Bioscience and School of Biology, Georgia Institute of Technology, Atlanta, GA, United States of America
Dev Biol 377:399-414. 2013..Our dissection of the molecular mechanics of vertebrate tooth replacement coupled to complex shape pinpoints aspects of odontogenesis that might be re-evolved in the lab to solve problems in regenerative dentistry...
Brain diversity evolves via differences in patterningJonathan B Sylvester
Parker H Petit Institute for Bioengineering and Biosciences and School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA
Proc Natl Acad Sci U S A 107:9718-23. 2010..In general, variation in developmental patterning might lay the foundations on which neurogenesis erects diverse brain architectures...
Developmental and evolutionary origins of the vertebrate dentition: molecular controls for spatio-temporal organisation of tooth sites in osteichthyansGareth J Fraser
MRC Centre for Developmental Neurobiology, King s College London, London, UK
J Exp Zool B Mol Dev Evol 306:183-203. 2006..Utilising the data generated from the rainbow trout model, we propose this as a standard for comparative development and evolutionary theories of the vertebrate dentition...
Conserved deployment of genes during odontogenesis across osteichthyansGareth J Fraser
Craniofacial Development, Dental Institute, King s College London, Guy s Tower, UK
Proc Biol Sci 271:2311-7. 2004....
Gene deployment for tooth replacement in the rainbow trout (Oncorhynchus mykiss): a developmental model for evolution of the osteichthyan dentitionGareth J Fraser
MRC Centre for Developmental Neurobiology, King's College London, London, UK
Evol Dev 8:446-57. 2006....
