Gang Bao

Summary

Affiliation: Georgia Institute of Technology
Country: USA

Publications

  1. pmc Target accessibility and signal specificity in live-cell detection of BMP-4 mRNA using molecular beacons
    Won Jong Rhee
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Nucleic Acids Res 36:e30. 2008
  2. pmc CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity
    Thomas J Cradick
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Nucleic Acids Res 41:9584-92. 2013
  3. pmc Slow non-specific accumulation of 2'-deoxy and 2'-O-methyl oligonucleotide probes at mitochondria in live cells
    Won Jong Rhee
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Nucleic Acids Res 38:e109. 2010
  4. pmc Translation inhibition reveals interaction of 2'-deoxy and 2'-O-methyl molecular beacons with mRNA targets in living cells
    Nitin Nitin
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Nucleic Acids Res 37:4977-86. 2009
  5. doi request reprint Multifunctional nanoparticles for drug delivery and molecular imaging
    Gang Bao
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Annu Rev Biomed Eng 15:253-82. 2013
  6. ncbi request reprint Engineering nanostructured probes for sensitive intracellular gene detection
    Gang Bao
    Departament of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Mech Chem Biosyst 1:23-36. 2004
  7. pmc Fluorescent probes for live-cell RNA detection
    Gang Bao
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, USA
    Annu Rev Biomed Eng 11:25-47. 2009
  8. pmc Peptide-linked molecular beacons for efficient delivery and rapid mRNA detection in living cells
    Nitin Nitin
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Nucleic Acids Res 32:e58. 2004
  9. ncbi request reprint Hybridization of 2'-O-methyl and 2'-deoxy molecular beacons to RNA and DNA targets
    Andrew Tsourkas
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Nucleic Acids Res 31:5168-74. 2003
  10. pmc Self-assembly of phospholipid-PEG coating on nanoparticles through dual solvent exchange
    Sheng Tong
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, United States
    Nano Lett 11:3720-6. 2011

Collaborators

Detail Information

Publications52

  1. pmc Target accessibility and signal specificity in live-cell detection of BMP-4 mRNA using molecular beacons
    Won Jong Rhee
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Nucleic Acids Res 36:e30. 2008
    ..Possible beacon design rules are identified and approaches for enhancing target accessibility are discussed. This has significant implications to MB design for live cell mRNA detection...
  2. pmc CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity
    Thomas J Cradick
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Nucleic Acids Res 41:9584-92. 2013
    ..Therefore, CRISPR/Cas9 systems need to be carefully designed to avoid potential off-target cleavage sites, including those with mismatches to the 12-bases proximal to the guide strand protospacer-adjacent motif. ..
  3. pmc Slow non-specific accumulation of 2'-deoxy and 2'-O-methyl oligonucleotide probes at mitochondria in live cells
    Won Jong Rhee
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Nucleic Acids Res 38:e109. 2010
    ..These results may help design and optimize fluorescence imaging probes for long-time RNA detection and monitoring in living cells...
  4. pmc Translation inhibition reveals interaction of 2'-deoxy and 2'-O-methyl molecular beacons with mRNA targets in living cells
    Nitin Nitin
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Nucleic Acids Res 37:4977-86. 2009
    ..This work may thus provide a significant insight into probe design for detection of RNA molecules in living cells and RNA biology...
  5. doi request reprint Multifunctional nanoparticles for drug delivery and molecular imaging
    Gang Bao
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Annu Rev Biomed Eng 15:253-82. 2013
    ....
  6. ncbi request reprint Engineering nanostructured probes for sensitive intracellular gene detection
    Gang Bao
    Departament of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Mech Chem Biosyst 1:23-36. 2004
    ..The underlying biological and biochemical aspects are illustrated...
  7. pmc Fluorescent probes for live-cell RNA detection
    Gang Bao
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, USA
    Annu Rev Biomed Eng 11:25-47. 2009
    ..It is expected that continued advancements in live cell imaging of RNA will open new and exciting opportunities in a wide range of biological and medical applications...
  8. pmc Peptide-linked molecular beacons for efficient delivery and rapid mRNA detection in living cells
    Nitin Nitin
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Nucleic Acids Res 32:e58. 2004
    ..The peptide-linked molecular beacons approach promises to open new and exciting opportunities in sensitive gene detection and quantification in vivo...
  9. ncbi request reprint Hybridization of 2'-O-methyl and 2'-deoxy molecular beacons to RNA and DNA targets
    Andrew Tsourkas
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Nucleic Acids Res 31:5168-74. 2003
    ..For the pairs tested, the 2'-deoxy-beacon/DNA-target duplex showed the fastest hybridization kinetics. These findings have significant implications for the design and application of molecular beacons...
  10. pmc Self-assembly of phospholipid-PEG coating on nanoparticles through dual solvent exchange
    Sheng Tong
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, United States
    Nano Lett 11:3720-6. 2011
    ....
  11. pmc SAPTA: a new design tool for improving TALE nuclease activity
    Yanni Lin
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, 30332, USA and Department of Pediatrics, Stanford University, Stanford, CA, 94305, USA
    Nucleic Acids Res 42:e47. 2014
    ..SAPTA can be accessed via the website at http://baolab.bme.gatech.edu/Research/BioinformaticTools/TAL_targeter.html. ..
  12. pmc Hybridization of 2'-O-methyl and 2'-deoxy molecular beacons to RNA and DNA targets
    Andrew Tsourkas
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Nucleic Acids Res 30:5168-74. 2002
    ..For the pairs tested, the 2'-deoxy-beacon/DNA-target duplex showed the fastest hybridization kinetics. These findings have significant implications for the design and application of molecular beacons...
  13. doi request reprint Indocyanine green loaded SPIO nanoparticles with phospholipid-PEG coating for dual-modal imaging and photothermal therapy
    Yan Ma
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Biomaterials 34:7706-14. 2013
    ..This is very helpful for accurately interpreting the obtained images, identifying the size and location of the tumor, as well as guiding and monitoring the photothermal therapy through a single agent...
  14. pmc Hybridization kinetics and thermodynamics of molecular beacons
    Andrew Tsourkas
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Nucleic Acids Res 31:1319-30. 2003
    ..Molecular beacons with very short stems have a lower signal-to-background ratio than molecular beacons with longer stems. These features have significant implications for the design of molecular beacons for various applications...
  15. pmc Surface ligand effects on metal-affinity coordination to quantum dots: implications for nanoprobe self-assembly
    Allison M Dennis
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, USA
    Bioconjug Chem 21:1160-70. 2010
    ..The results of this systematic comparison can provide a basis for rational design of self-assembled biomolecule-QD complexes for biomedical applications...
  16. pmc Tiny grains give huge gains: nanocrystal-based signal amplification for biomolecule detection
    Sheng Tong
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, USA
    ACS Nano 7:5142-50. 2013
    ..This novel method adds a new dimension to current nanoparticle-based bioassays. ..
  17. pmc Quantum dot-fluorescent protein FRET probes for sensing intracellular pH
    Allison M Dennis
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 313 Ferst Drive, Atlanta, Georgia 30332, United States
    ACS Nano 6:2917-24. 2012
    ..These probes have the potential to enjoy a wide range of intracellular pH imaging applications that may not be feasible with fluorescent proteins or organic fluorophores alone...
  18. ncbi request reprint Nanostructured probes for RNA detection in living cells
    Philip Santangelo
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA
    Ann Biomed Eng 34:39-50. 2006
    ..The nanostructured probes promise to open new and exciting opportunities in sensitive gene detection for a wide range of biological and medical applications...
  19. ncbi request reprint Spectroscopic features of dual fluorescence/luminescence resonance energy-transfer molecular beacons
    Andrew Tsourkas
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, USA
    Anal Chem 75:3697-703. 2003
    ..These new approaches allow for the ultrasensitive detection of target molecules in a way that could be readily applied to real-time imaging of gene expression in living cells...
  20. pmc Dual FRET molecular beacons for mRNA detection in living cells
    Philip J Santangelo
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Nucleic Acids Res 32:e57. 2004
    ..2. We further revealed intriguing details of K-ras and survivin mRNA localization in living cells. The dual FRET molecular beacons approach provides a novel technique for sensitive RNA detection and quantification in living cells...
  21. ncbi request reprint Direct visualization of mRNA colocalization with mitochondria in living cells using molecular beacons
    Philip J Santangelo
    Georgia Institute of Technology and Emory University, Department of Biomedical Engineering, Atlanta, Georgia 30332, USA
    J Biomed Opt 10:44025. 2005
    ..Our observation reveals intriguing subcellular associations of mRNA with organelles such as mitochondria, which may provide new insight into the transport, dynamics, and functions of mRNA and mRNA-protein interactions...
  22. ncbi request reprint The use of molecular beacons to detect and quantify microRNA
    Meredith B Baker
    Division of Cardiology, Emory University School of Medicine, Atlanta, GA, USA
    Methods Mol Biol 1039:279-87. 2013
    ..Here, we describe the methods for designing and using molecular beacons to detect and quantify miRNA...
  23. pmc Simultaneous detection of mRNA and protein stem cell markers in live cells
    Won Jong Rhee
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, USA
    BMC Biotechnol 9:30. 2009
    ..Here we report the detection of Oct-4 mRNA and SSEA-1 protein in live carcinoma stem cells using respectively molecular beacon and dye-labeled antibody, aiming to establish a new method for stem cells detection and isolation...
  24. pmc Tat peptide is capable of importing large nanoparticles across nuclear membrane in digitonin permeabilized cells
    Nitin Nitin
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Ann Biomed Eng 37:2018-27. 2009
    ..These results have significant implications for the development of new approaches for delivery of cargo into the nuclei of living cells...
  25. pmc Structure-function relationships of shared-stem and conventional molecular beacons
    Andrew Tsourkas
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 315 Ferst Drive, Suite 2306, Atlanta, GA 30332, USA
    Nucleic Acids Res 30:4208-15. 2002
    ..These findings should enable better design of molecular beacons for various applications...
  26. pmc An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage
    Eli J Fine
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Nucleic Acids Res 42:e42. 2014
    ....
  27. pmc Use of molecular beacons to image effects of titanium surface microstructure on beta1 integrin expression in live osteoblast-like cells
    Frances E Lennon
    Wallace H Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332 0363, USA
    Biomaterials 31:7640-7. 2010
    ..This technique overcomes the limitations of traditional gene assays (PCR, immunofluorescence) by allowing for the real-time measurement and tracking of specific mRNAs in individual live cells prior to confluence...
  28. pmc Coating optimization of superparamagnetic iron oxide nanoparticles for high T2 relaxivity
    Sheng Tong
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, United States
    Nano Lett 10:4607-13. 2010
    ..With 14 nm core and PEG1000 coating, SPIOs can have T2 relaxivity of 385 s-1 mM-1, which is among the highest per-Fe atom relaxivities. In vivo tumor imaging results demonstrated the potential of the SPIOs for clinical applications...
  29. doi request reprint Block copolymer-based gadolinium nanoparticles as MRI contrast agents with high T1 relaxivity
    Sijian Hou
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University Atlanta, GA 30332, USA
    Nanomedicine (Lond) 7:211-8. 2012
    ..To synthesize block copolymer-based gadolinium nanoparticles (Gd-NPs) and evaluate their potential as a new MRI contrast agent...
  30. pmc In vitro quantification of specific microRNA using molecular beacons
    Meredith B Baker
    Division of Cardiology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Nucleic Acids Res 40:e13. 2012
    ..These results suggest that the molecular beacon-based approach to assess miRNA expression and distinguish mature and precursor miRNA species is quite robust, and has the promise for assessing miRNA levels in biological samples...
  31. pmc In vivo evaluation of (64)Cu-labeled magnetic nanoparticles as a dual-modality PET/MR imaging agent
    Charles Glaus
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia, USA
    Bioconjug Chem 21:715-22. 2010
    ..Biodistribution and in vivo PET/CT imaging studies of the probes showed a circulation half-life of 143 min and high initial blood retention with moderate liver uptake, making them an attractive contrast agent for disease studies...
  32. pmc Molecular beacons can assess changes in expression and 3'-polyadenylation of human eNOS mRNA
    Rachel Jones
    Div of Cardiology, Emory Univ School of Medicine, Atlanta, GA 30322, USA
    Am J Physiol Cell Physiol 296:C498-504. 2009
    ..This approach could easily be adapted for studies of other endothelial genes and has promise for applications in live endothelial cells...
  33. pmc Nanomedicine: tiny particles and machines give huge gains
    Sheng Tong
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, 30332, USA
    Ann Biomed Eng 42:243-59. 2014
    ..The challenges in translating nanomedicine approaches to clinical applications are discussed. ..
  34. doi request reprint Quantum dot-fluorescent protein pairs as novel fluorescence resonance energy transfer probes
    Allison M Dennis
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 313 Ferst Drive, Atlanta, Georgia 30332, USA
    Nano Lett 8:1439-45. 2008
    ..This provides a novel approach to developing QD-based FRET probes for biomedical applications...
  35. pmc Purification of cardiomyocytes from differentiating pluripotent stem cells using molecular beacons that target cardiomyocyte-specific mRNA
    Kiwon Ban
    Division of Cardiology, Department of Medicine K B, S K, H J P, J B, K W C, Y S Y and Department of Anesthesiology M K S, S P Y, Emory University School of Medicine, Atlanta, GA Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA B W, G B Division of Cardiology, Department of Internal Medicine, Seoul St Mary s Hospital, The Catholic University of Korea, Seoul, Republic of Korea H J P and Department of Pediatrics, Emory University School of Medicine and Children s Healthcare of Atlanta, Atlanta, GA T S, M W
    Circulation 128:1897-909. 2013
    ..MBs are nanoscale probes that emit a fluorescence signal when hybridized to target mRNAs...
  36. pmc HuR regulates the expression of stress-sensitive genes and mediates inflammatory response in human umbilical vein endothelial cells
    Won Jong Rhee
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Proc Natl Acad Sci U S A 107:6858-63. 2010
    ..Taken together, these results suggest that HuR plays a critical role in inducing inflammatory response of endothelial cells under mechanical and biochemical stresses...
  37. pmc Live-cell characterization and analysis of a clinical isolate of bovine respiratory syncytial virus, using molecular beacons
    Philip Santangelo
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 313 Ferst Dr, Atlanta, GA 30332, USA
    J Virol 80:682-8. 2006
    ..Taken together, the use of molecular beacons for active virus imaging provides a powerful tool for rapid viral infection detection, the characterization of RNA viruses, and the design of new antiviral drugs...
  38. pmc Dynamics of filamentous viral RNPs prior to egress
    Philip J Santangelo
    Wallace H Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 313 Ferst Drive, Atlanta, GA 30332, USA
    Nucleic Acids Res 35:3602-11. 2007
    ....
  39. doi request reprint Engineering imaging probes and molecular machines for nanomedicine
    Sheng Tong
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Sci China Life Sci 55:843-61. 2012
    ..The challenges in translating nanomedicine approaches to clinical applications are discussed...
  40. ncbi request reprint A filtration-based protein microarray technique
    Yangqing Xu
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, USA
    Anal Chem 75:5345-51. 2003
    ..The potential clinical applications of the filtration-based protein microarrays were demonstrated by detecting carcinoembryonic antigen in human plasma samples...
  41. pmc NLS peptide conjugated molecular beacons for visualizing nuclear RNA in living cells
    Nitin Nitin
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, USA
    Bioconjug Chem 19:2205-11. 2008
    ..The results were validated using in situ hybridization as positive control and random beacons as negative control. This novel approach may be applied to imaging other nuclear RNAs and pre-mRNAs in living cells...
  42. pmc MicroRNA Expression Profile in CAD Patients and the Impact of ACEI/ARB
    Martina Weber
    Division of Cardiology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Cardiol Res Pract 2011:532915. 2011
    ..Importantly, medication use may significantly alter miRNA expression. These findings may have significant implications for identifying and managing individuals that either have CAD or are at risk of developing the disease...
  43. pmc CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences
    Yanni Lin
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Nucleic Acids Res 42:7473-85. 2014
    ..Our results strongly indicate the need to perform comprehensive off-target analysis related to DNA and sgRNA bulges in addition to base mismatches, and suggest specific guidelines for reducing potential off-target cleavage. ..
  44. doi request reprint Identification of off-target cleavage sites of zinc finger nucleases and TAL effector nucleases using predictive models
    Eli J Fine
    Wallace H Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA
    Methods Mol Biol 1114:371-83. 2014
    ..Here, we describe a method to test for nuclease cleavage at potential off-target sites predicted by bioinformatics models. ..
  45. doi request reprint High-throughput cellular screening of engineered nuclease activity using the single-strand annealing assay and luciferase reporter
    Thomas J Cradick
    Wallace H Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA
    Methods Mol Biol 1114:339-52. 2014
    ..We have used this robust process to investigate the activity of zinc finger nucleases (ZFNs) and transcription activated-like effector nucleases (TALENs)...
  46. ncbi request reprint Shedding light on health and disease using molecular beacons
    Andrew Tsourkas
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA
    Brief Funct Genomic Proteomic 1:372-84. 2003
    ..The aim of this paper is to foster the development of new molecular beacon-based assays and to stimulate the application of this technology in laboratory and clinical studies of health and disease...
  47. doi request reprint Designing and testing the activities of TAL effector nucleases
    Yanni Lin
    Wallace H Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA
    Methods Mol Biol 1114:203-19. 2014
    ..Here we describe a procedure to design active TALENs using a scoring system named Scoring Algorithm for Predicted TALEN Activity (SAPTA) and a method to test the activity of individual and pairs of TALENs. ..
  48. pmc Receptor-mediated delivery of engineered nucleases for genome modification
    Zhong Chen
    Department of Anesthesiology and Perioperative Medicine, Georgia Regents University, 1120 15th Street, Augusta, GA 30912, USA, Department of Radiation Oncology, Emory University School of Medicine, 4121 Rollins Research Center, 1510 Clifton Rd NE, Atlanta, GA 30322, USA, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA, Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30322, USA, Department of Pediatrics Divisions of Hematology Oncology and Human Gene Therapy, Stanford University School of Medicine, Stanford, CA 94305, USA and Department of Biochemistry, Emory University School of Medicine, 4121 Rollins Research Center, 1510 Clifton Rd NE, Atlanta, GA 30322, USA
    Nucleic Acids Res 41:e182. 2013
    ..The approach is flexible and general, with the potential for extension to other targeting ligands and nuclease architectures. ..
  49. doi request reprint Magnetic targeting of human mesenchymal stem cells with internalized superparamagnetic iron oxide nanoparticles
    Natalia Landazuri
    Division of Cardiology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Small 9:4017-26. 2013
    ..The results suggest that, by loading SPIOs into hMSCs and applying appropriate magnetic field gradients, it is possible to target hMSCs to particular vascular networks. ..
  50. ncbi request reprint Coating thickness of magnetic iron oxide nanoparticles affects R2 relaxivity
    Leslie E W LaConte
    Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, USA
    J Magn Reson Imaging 26:1634-41. 2007
    ..To evaluate the effect of coating thickness on the relaxivity of iron oxide nanoparticles...
  51. ncbi request reprint An in vitro uniaxial stretch model for axonal injury
    Bryan J Pfister
    Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA
    Ann Biomed Eng 31:589-98. 2003
    ..This device can be used to investigate a wide range of biomechanical issues involved in diffuse axonal injury...
  52. ncbi request reprint DNA functionalized single-walled carbon nanotubes for electrochemical detection
    Chenguo Hu
    Department of Applied Physics, Chongqing University, Chongqing 400044, China
    J Phys Chem B 109:20072-6. 2005
    ..This was demonstrated by highly selective and sensitive detection of a low concentration of dopamine in the presence of excess ascorbic acid...

Research Grants7

  1. Nanomachines for RNA Synthesis and DNA Repair (RMI)
    Gang Bao; Fiscal Year: 2004
    ..The detailed plan for the GNC will be developed from results of this workshop and also through further preliminary studies that couple nanotechnology tools and models with the selected biological phenomena. ..
  2. In vivo gene detection for cancer analysis
    Gang Bao; Fiscal Year: 2007
    ....
  3. Nanotechnology: Detection & Analysis of Plaque Formation
    Gang Bao; Fiscal Year: 2007
    ..In additional to basic knowledge on cardiology, this PEN is expected to yield methodologies that can direct impact on clinical practice of early detection, diagnosis and treatment of atherosclerosis. ..
  4. Nanomedicine Center for Nucleoprotein Machines
    Gang Bao; Fiscal Year: 2007
    ..Our long-term vision is to provide genetic cures for common human diseases based on the ability to manipulate the somatic human genome using Nanomedicine. ..