Yun Ling Zheng

Summary

Affiliation: Georgetown University
Country: USA

Publications

  1. pmc Telomere attrition in cancer cells and telomere length in tumor stroma cells predict chromosome instability in esophageal squamous cell carcinoma: a genome-wide analysis
    Yun Ling Zheng
    Cancer Genetics and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia 20057, USA
    Cancer Res 69:1604-14. 2009
  2. pmc Chromosome 9 arm-specific telomere length and breast cancer risk
    Yun Ling Zheng
    Cancer Genetics and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA
    Carcinogenesis 30:1380-6. 2009
  3. pmc Telomere length in blood cells and breast cancer risk: investigations in two case-control studies
    Yun Ling Zheng
    Cancer Genetics and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA
    Breast Cancer Res Treat 120:769-75. 2010
  4. pmc Phytohemagglutinin-induced mitotic index in blood lymphocytes: a potential biomarker for breast cancer risk
    Ourania Kosti
    Carcinogenesis, Biomarkers and Epidemiology Program, Department of Oncology, Lombardi Comprehensive Cancer Center, Washington DC, USA
    Breast Cancer (Auckl) 4:73-83. 2010
  5. pmc MicroRNA-9 as potential biomarker for breast cancer local recurrence and tumor estrogen receptor status
    Xin Zhou
    Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA
    PLoS ONE 7:e39011. 2012
  6. pmc Telomere deficiencies on chromosomes 9p, 15p, 15q and Xp: potential biomarkers for breast cancer risk
    Yun Ling Zheng
    Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA
    Hum Mol Genet 20:378-86. 2011
  7. pmc Mutagen sensitivity, tobacco smoking and breast cancer risk: a case-control study
    Ourania Kosti
    Department of Oncology, Carcinogenesis, Biomarkers and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA
    Carcinogenesis 31:654-9. 2010
  8. pmc Genetic polymorphisms in NQO1 and SOD2: interactions with smoking, schistosoma infection, and bladder cancer risk in Egypt
    David Goerlitz
    Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC
    Urol Oncol 32:47.e15-20. 2014
  9. pmc Telomere length variation in normal epithelial cells adjacent to tumor: potential biomarker for breast cancer local recurrence
    Xin Zhou
    Carcinogenesis, Biomarkers and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA
    Carcinogenesis 33:113-8. 2012
  10. pmc GSTM1, GSTT1 null variants, and GPX1 single nucleotide polymorphism are not associated with bladder cancer risk in Egypt
    David Goerlitz
    Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA
    Cancer Epidemiol Biomarkers Prev 20:1552-4. 2011

Collaborators

Detail Information

Publications15

  1. pmc Telomere attrition in cancer cells and telomere length in tumor stroma cells predict chromosome instability in esophageal squamous cell carcinoma: a genome-wide analysis
    Yun Ling Zheng
    Cancer Genetics and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia 20057, USA
    Cancer Res 69:1604-14. 2009
    ..This study provides evidence that telomere shortening is a common genetic alteration in ESCC and that chromosome arm instability is related to both telomere attrition in cancer cells and telomere length in tumor stroma cells...
  2. pmc Chromosome 9 arm-specific telomere length and breast cancer risk
    Yun Ling Zheng
    Cancer Genetics and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA
    Carcinogenesis 30:1380-6. 2009
    ..However, the influence of telomere lengths of specific chromosomal arms on the breast cancer risk is unknown...
  3. pmc Telomere length in blood cells and breast cancer risk: investigations in two case-control studies
    Yun Ling Zheng
    Cancer Genetics and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA
    Breast Cancer Res Treat 120:769-75. 2010
    ..Overall telomere length in blood leukocytes was not significantly associated with the risk of breast cancer...
  4. pmc Phytohemagglutinin-induced mitotic index in blood lymphocytes: a potential biomarker for breast cancer risk
    Ourania Kosti
    Carcinogenesis, Biomarkers and Epidemiology Program, Department of Oncology, Lombardi Comprehensive Cancer Center, Washington DC, USA
    Breast Cancer (Auckl) 4:73-83. 2010
    ..However, biomarkers of cell proliferation in response to environmental stimuli have not been adequately explored for breast cancer risk...
  5. pmc MicroRNA-9 as potential biomarker for breast cancer local recurrence and tumor estrogen receptor status
    Xin Zhou
    Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA
    PLoS ONE 7:e39011. 2012
    ..02). Expression levels of miR-9 and another miR candidate, miR-375, were also strongly associated with ER status (p<0.001 for both). The potential of miR-9 as a biomarker for LR warrants further investigation with larger sample size...
  6. pmc Telomere deficiencies on chromosomes 9p, 15p, 15q and Xp: potential biomarkers for breast cancer risk
    Yun Ling Zheng
    Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA
    Hum Mol Genet 20:378-86. 2011
    ..If confirmed in future studies, chromosomal arm-specific telomeres are likely to be a useful panel of blood-based biomarkers for breast cancer risk assessment, given their strong associations with breast cancer risk...
  7. pmc Mutagen sensitivity, tobacco smoking and breast cancer risk: a case-control study
    Ourania Kosti
    Department of Oncology, Carcinogenesis, Biomarkers and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA
    Carcinogenesis 31:654-9. 2010
    ..The mutagen sensitivity assay (MSA), a phenotypic marker of DNA damage response and repair capacity, has been consistently shown to associate with the risk of tobacco-related cancers...
  8. pmc Genetic polymorphisms in NQO1 and SOD2: interactions with smoking, schistosoma infection, and bladder cancer risk in Egypt
    David Goerlitz
    Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC
    Urol Oncol 32:47.e15-20. 2014
    ..Bladder cancer is the most prevalent form of cancer in men among Egyptians, for whom tobacco smoke exposure and Schistosoma haematobium (SH) infection are the major risk factors. We hypothesized that functional polymorphisms in..
  9. pmc Telomere length variation in normal epithelial cells adjacent to tumor: potential biomarker for breast cancer local recurrence
    Xin Zhou
    Carcinogenesis, Biomarkers and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA
    Carcinogenesis 33:113-8. 2012
    ..If confirmed by future studies, TLV in normal epithelial cells adjacent to tumor has the potential to become a promising biomarker for predicting breast cancer LR after breast conserving surgery...
  10. pmc GSTM1, GSTT1 null variants, and GPX1 single nucleotide polymorphism are not associated with bladder cancer risk in Egypt
    David Goerlitz
    Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA
    Cancer Epidemiol Biomarkers Prev 20:1552-4. 2011
    ....
  11. pmc Elevated lung cancer risk is associated with deficiencies in cell cycle checkpoints: genotype and phenotype analyses from a case-control study
    Yun Ling Zheng
    Cancer Genetics and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC, USA
    Int J Cancer 126:2199-210. 2010
    ..The data also suggested that the function of G(2)/M checkpoint is modulated by genetic polymorphisms in genes involved in DNA repair and cell cycle control...
  12. pmc Urinary bladder cancer risk factors in Egypt: a multicenter case-control study
    Yun Ling Zheng
    Carcinogenesis, Biomarkers and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia 20057, USA
    Cancer Epidemiol Biomarkers Prev 21:537-46. 2012
    ..We investigated associations between tobacco exposure, history of schistosomiasis, and bladder cancer risk in Egypt...
  13. ncbi request reprint Simultaneous quantification of alternatively spliced transcripts in a single droplet digital PCR reaction
    Bing Sun
    Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC
    Biotechniques 56:319-25. 2014
    ....
  14. pmc Metabolism of isothiocyanates in individuals with positive and null GSTT1 and M1 genotypes after drinking watercress juice
    Marcin Dyba
    Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, District of Columbia, Washington, DC 20057, USA
    Clin Nutr 29:813-8. 2010
    ..In this study, we examined one possible mechanism: whether subjects with null genotypes excrete ITCs at a slower rate than those with positive genotypes after drinking watercress juice, a rich source of ITCs...
  15. pmc Serum concentrations of cytokines and lung cancer survival in African Americans and Caucasians
    Lindsey Enewold
    Lombardi Cancer Center, Georgetown University, Washington, District of Columbia, USA
    Cancer Epidemiol Biomarkers Prev 18:215-22. 2009
    ....

Research Grants2

  1. Telomere dysfunction, chromosome 9 instability and bladder cancer risk
    Yun Ling Zheng; Fiscal Year: 2009
    ..The new knowledge to be generated will provide insights in understanding the etiology of bladder carcinogenesis and pave the way for the development of new and better clinical tools for early detection and diagnosis. ..
  2. Telomere dysfunction, chromosome 9 instability and bladder cancer risk
    Yun Ling Zheng; Fiscal Year: 2010
    ..The new knowledge to be generated will provide insights in understanding the etiology of bladder carcinogenesis and pave the way for the development of new and better clinical tools for early detection and diagnosis. ..