Yun Ling Zheng

Summary

Affiliation: Georgetown University
Country: USA

Publications

  1. ncbi Telomere attrition in cancer cells and telomere length in tumor stroma cells predict chromosome instability in esophageal squamous cell carcinoma: a genome-wide analysis
    Yun Ling Zheng
    Cancer Genetics and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia 20057, USA
    Cancer Res 69:1604-14. 2009
  2. ncbi Chromosome 9 arm-specific telomere length and breast cancer risk
    Yun Ling Zheng
    Cancer Genetics and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA
    Carcinogenesis 30:1380-6. 2009
  3. ncbi Telomere length in blood cells and breast cancer risk: investigations in two case-control studies
    Yun Ling Zheng
    Cancer Genetics and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA
    Breast Cancer Res Treat 120:769-75. 2010
  4. ncbi Telomere deficiencies on chromosomes 9p, 15p, 15q and Xp: potential biomarkers for breast cancer risk
    Yun Ling Zheng
    Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA
    Hum Mol Genet 20:378-86. 2011
  5. ncbi Mutagen sensitivity, tobacco smoking and breast cancer risk: a case-control study
    Ourania Kosti
    Department of Oncology, Carcinogenesis, Biomarkers and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA
    Carcinogenesis 31:654-9. 2010
  6. ncbi MicroRNA-9 as potential biomarker for breast cancer local recurrence and tumor estrogen receptor status
    Xin Zhou
    Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA
    PLoS ONE 7:e39011. 2012
  7. ncbi Telomere length variation in normal epithelial cells adjacent to tumor: potential biomarker for breast cancer local recurrence
    Xin Zhou
    Carcinogenesis, Biomarkers and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA
    Carcinogenesis 33:113-8. 2012
  8. ncbi GSTM1, GSTT1 null variants, and GPX1 single nucleotide polymorphism are not associated with bladder cancer risk in Egypt
    David Goerlitz
    Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA
    Cancer Epidemiol Biomarkers Prev 20:1552-4. 2011
  9. ncbi Urinary bladder cancer risk factors in Egypt: a multicenter case-control study
    Yun Ling Zheng
    Carcinogenesis, Biomarkers and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia 20057, USA
    Cancer Epidemiol Biomarkers Prev 21:537-46. 2012
  10. ncbi Phytohemagglutinin-induced mitotic index in blood lymphocytes: a potential biomarker for breast cancer risk
    Ourania Kosti
    Carcinogenesis, Biomarkers and Epidemiology Program, Department of Oncology, Lombardi Comprehensive Cancer Center, Washington DC, USA
    Breast Cancer (Auckl) 4:73-83. 2010

Research Grants

  1. Telomere dysfunction, chromosome 9 instability and bladder cancer risk
    Yun Ling Zheng; Fiscal Year: 2009
  2. Telomere dysfunction, chromosome 9 instability and bladder cancer risk
    Yun Ling Zheng; Fiscal Year: 2010

Collaborators

Detail Information

Publications13

  1. ncbi Telomere attrition in cancer cells and telomere length in tumor stroma cells predict chromosome instability in esophageal squamous cell carcinoma: a genome-wide analysis
    Yun Ling Zheng
    Cancer Genetics and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia 20057, USA
    Cancer Res 69:1604-14. 2009
    ..This study provides evidence that telomere shortening is a common genetic alteration in ESCC and that chromosome arm instability is related to both telomere attrition in cancer cells and telomere length in tumor stroma cells...
  2. ncbi Chromosome 9 arm-specific telomere length and breast cancer risk
    Yun Ling Zheng
    Cancer Genetics and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA
    Carcinogenesis 30:1380-6. 2009
    ..However, the influence of telomere lengths of specific chromosomal arms on the breast cancer risk is unknown...
  3. ncbi Telomere length in blood cells and breast cancer risk: investigations in two case-control studies
    Yun Ling Zheng
    Cancer Genetics and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA
    Breast Cancer Res Treat 120:769-75. 2010
    ..Overall telomere length in blood leukocytes was not significantly associated with the risk of breast cancer...
  4. ncbi Telomere deficiencies on chromosomes 9p, 15p, 15q and Xp: potential biomarkers for breast cancer risk
    Yun Ling Zheng
    Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA
    Hum Mol Genet 20:378-86. 2011
    ..If confirmed in future studies, chromosomal arm-specific telomeres are likely to be a useful panel of blood-based biomarkers for breast cancer risk assessment, given their strong associations with breast cancer risk...
  5. ncbi Mutagen sensitivity, tobacco smoking and breast cancer risk: a case-control study
    Ourania Kosti
    Department of Oncology, Carcinogenesis, Biomarkers and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA
    Carcinogenesis 31:654-9. 2010
    ..Our observation that the effect of tobacco smoking on breast cancer risk may differ based on mutagen sensitivity status warrants further investigation...
  6. ncbi MicroRNA-9 as potential biomarker for breast cancer local recurrence and tumor estrogen receptor status
    Xin Zhou
    Cancer Prevention and Control Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA
    PLoS ONE 7:e39011. 2012
    ..02). Expression levels of miR-9 and another miR candidate, miR-375, were also strongly associated with ER status (p<0.001 for both). The potential of miR-9 as a biomarker for LR warrants further investigation with larger sample size...
  7. ncbi Telomere length variation in normal epithelial cells adjacent to tumor: potential biomarker for breast cancer local recurrence
    Xin Zhou
    Carcinogenesis, Biomarkers and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA
    Carcinogenesis 33:113-8. 2012
    ..If confirmed by future studies, TLV in normal epithelial cells adjacent to tumor has the potential to become a promising biomarker for predicting breast cancer LR after breast conserving surgery...
  8. ncbi GSTM1, GSTT1 null variants, and GPX1 single nucleotide polymorphism are not associated with bladder cancer risk in Egypt
    David Goerlitz
    Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA
    Cancer Epidemiol Biomarkers Prev 20:1552-4. 2011
    ....
  9. ncbi Urinary bladder cancer risk factors in Egypt: a multicenter case-control study
    Yun Ling Zheng
    Carcinogenesis, Biomarkers and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia 20057, USA
    Cancer Epidemiol Biomarkers Prev 21:537-46. 2012
    ..We investigated associations between tobacco exposure, history of schistosomiasis, and bladder cancer risk in Egypt...
  10. ncbi Phytohemagglutinin-induced mitotic index in blood lymphocytes: a potential biomarker for breast cancer risk
    Ourania Kosti
    Carcinogenesis, Biomarkers and Epidemiology Program, Department of Oncology, Lombardi Comprehensive Cancer Center, Washington DC, USA
    Breast Cancer (Auckl) 4:73-83. 2010
    ..However, biomarkers of cell proliferation in response to environmental stimuli have not been adequately explored for breast cancer risk...
  11. ncbi Elevated lung cancer risk is associated with deficiencies in cell cycle checkpoints: genotype and phenotype analyses from a case-control study
    Yun Ling Zheng
    Cancer Genetics and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC, USA
    Int J Cancer 126:2199-210. 2010
    ..The data also suggested that the function of G(2)/M checkpoint is modulated by genetic polymorphisms in genes involved in DNA repair and cell cycle control...
  12. ncbi Metabolism of isothiocyanates in individuals with positive and null GSTT1 and M1 genotypes after drinking watercress juice
    Marcin Dyba
    Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, District of Columbia, Washington, DC 20057, USA
    Clin Nutr 29:813-8. 2010
    ..In this study, we examined one possible mechanism: whether subjects with null genotypes excrete ITCs at a slower rate than those with positive genotypes after drinking watercress juice, a rich source of ITCs...
  13. ncbi Serum concentrations of cytokines and lung cancer survival in African Americans and Caucasians
    Lindsey Enewold
    Lombardi Cancer Center, Georgetown University, Washington, District of Columbia, USA
    Cancer Epidemiol Biomarkers Prev 18:215-22. 2009
    ....

Research Grants2

  1. Telomere dysfunction, chromosome 9 instability and bladder cancer risk
    Yun Ling Zheng; Fiscal Year: 2009
    ..The new knowledge to be generated will provide insights in understanding the etiology of bladder carcinogenesis and pave the way for the development of new and better clinical tools for early detection and diagnosis. ..
  2. Telomere dysfunction, chromosome 9 instability and bladder cancer risk
    Yun Ling Zheng; Fiscal Year: 2010
    ..The new knowledge to be generated will provide insights in understanding the etiology of bladder carcinogenesis and pave the way for the development of new and better clinical tools for early detection and diagnosis. ..