M D Schwartz

..The goal of the current study was to examine whether a brief educational booklet regarding BRCA1/BRCA2 testing would influence knowledge, attitudes, and interest in testing among Ashkenazi Jewish women from the general population...

..The purpose of the trial was to determine the effect of the interventions on knowledge, decisional conflict, satisfaction with the screening decision, and self-reported screening...

..We describe the development of two DAs, a booklet and an interactive website, each with a values clarification component and designed for use in diverse settings...

..Here, we explore the relationships between the MSA and the Rad51 gene, which encodes a DNA repair enzyme that interacts with BRCA1 and BRCA2, in BRCA1 mutation carriers and women with sporadic breast cancer...

..In particular, the authors discuss the role of anxiety and worry in relation to testing and surgery decisions...

..In this study, we evaluated factors associated with the decision to undergo BRCA1/BRCA2 gene testing at the time of initial breast cancer diagnosis...

..In the present study, we prospectively evaluated the impact on surgical decision-making of pretreatment genetic counseling and BRCA1/BRCA2 testing among breast cancer patients at high-risk for carrying a mutation...

..In this study, we prospectively examined the impact of BRCA1/2 testing on the utilization of prophylactic oophorectomy and ovarian cancer screening. Participants and..

..Additional research is needed to determine the prospective association between distress and adherence and to identify potential mechanisms for such an association...

..To help BRCA1/2 carriers make this decision, the authors developed a computer-based interactive decision aid that was tested against usual care in a randomized controlled trial...

..The objective of this study was to examine the long-term psychologic impact of receiving BRCA1/2 test results within a clinic-based testing program...

..We evaluated long-term uptake and predictors of risk-reducing mastectomy (RRM), risk-reducing bilateral salpingo-oophorectomy (RRBSO), chemoprevention, and cancer screening among women at a mean of 5.3 years after testing...

..Finally, participants were significantly less willing to participate in research that examined stereotypical or potentially stigmatizing traits as opposed to research that examined medical or mental illnesses...

..2; 95% CIs, 0.4 and 3.0). These results highlight the role that spirituality may play in the decision-making process about genetic testing...

..After test results were disclosed, greater distress was associated with testing positive for a mutation. The implications of the findings for breast and ovarian cancer patients are discussed...

..In this study, we compared the impact of BRCA1/2 genetic test result and CPM on these outcomes among newly diagnosed breast cancer patients who opted for CPM at the time of their definitive surgical treatment versus patients who did not...

..The results are discussed in terms of their implications regarding interventions designed to increase mammography utilization in this population...

..We evaluated the impact of individualized breast cancer risk counseling on mammography use among women at risk for breast cancer...

..The project represented a collaboration between the Most Worshipful Prince Hall Grand Lodge of the District of Columbia and the Lombardi Cancer Center of Georgetown University...

..The aim of this study was to develop and evaluate a new measure for use in genetic research and consultation, known as the Pediatric BRCA1/2 Testing Attitudes Scale (P-TAS)...

..We assessed the extent to which a sample of AA men wished to engage in SDM regarding PCS and the demographic and psychological characteristics associated with SDM preferences...

..These results also highlight the unique opportunities for studying food aversion formation in the oncology setting...

..To describe breast cancer risk perceptions, determine risk comprehension, and evaluate mammography adherence among Latinas...

..In addition, procedural aspects of the genetic counseling intervention and the novel tools developed to facilitate this process and to ensure adequate counselor training and quality assurance are described...

..This electronic educational tool was well-accepted by patients and may be particularly useful for patients who desire less control over their treatment decisions and who are less proactive in seeking information on their own...

..Noncarriers had very good adherence to general population screening guidelines...

..This study examined whether ethnic differences in the use of Pap screening were associated with differences in cultural views, controlling for demographic and access factors...

..001). Receipt of BRCA1/2 mutation test results impacts how carriers see the positive aspects of RRO and RRM and their surgical intentions. Both the positive and negative aspects predict uptake of surgery...

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..This study examined the collective impact of knowledge, cultural views, and health beliefs on intentions to obtain mammography among Chinese women who had not had a mammogram in the previous year...

..To reduce the risk of contralateral breast cancer, some patients opt for prophylactic surgery of the unaffected breast (contralateral prophylactic mastectomy, CPM) in addition to mastectomy of the affected breast...

..To assess physician recommendations about the use of tamoxifen in premenopausal BRCA1 and BRCA2 mutation carriers...

..We also sought to identify the factors associated with provision of a blood sample to the FCR...

..In conjunction with enhanced genetic counseling focusing on family disclosure, educational literature, and psychosocial support may promote improved outcomes...

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..The objective of this article is to systematically review existing research on short-term effects of prevention, genetic counseling and testing, and screening activities on quality of life...

..This video might have the potential to increase adherence to mammography screening in Chinese women...

..Chinese cultural views consist of at least seven domains and may influence older women's breast, cervical, and CRC screening...

..This study investigated the hypothesis that adherence to colon cancer screening guidelines among Chinese women was associated with Eastern cultural views and anxiety about developing colon cancer...

..We examined the effect of the intervention on distress and the concerns related to genetic testing...

..We explored interest in genetic testing for genes related to modest changes in breast cancer risk in women at moderate to high risk for breast cancer...

..Although the use of multiple items may provide more information than when only a single method is used, different conclusions may be reached depending on the context in which an item is assessed...

..Our observation that the effect of tobacco smoking on breast cancer risk may differ based on mutagen sensitivity status warrants further investigation...

..77), and Positive Experiences (4 items, alpha = .75). All 3 MICRA subscales differentiated participants who were BRCA1/2 positive from the other 3 groups. MICRA thus helps identify subgroups of vulnerable genetic testing participants...

..001). These results suggest that interventions designed to address perceptions of stress related to medical decision-making and familial concerns may need to be targeted to BRCA1/2 mutation carriers and individuals who are highly anxious...

..The clinical and research implications of these results are discussed...

..abstract_text> ..

..UC on quality of life and psychosocial well-being; 3) To identify baseline factors that predict who is most and least likely to benefit from RGC; and 4) to evaluate the cost effectiveness of the RGC intervention. ..

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..The proposed cost-effectiveness analysis will incorporate prospective data on patient preferences and outcomes together with secondary data from the literature, into a decision-analytic model. ..

..If effective, the IDA can easily be disseminated to BRCA1/2 carriers across the country and adapted for use with other populations with inherited risk for cancer. ..

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