Research Topics
Species | Beth N PeshkinSummaryAffiliation: Georgetown University Country: USA Publications
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Publications
Utilization of breast cancer screening in a clinically based sample of women after BRCA1/2 testingBeth N Peshkin
Lombardi Cancer Center, Georgetown University, Washington, DC 20007, USA
Cancer Epidemiol Biomarkers Prev 11:1115-8. 2002..Noncarriers had very good adherence to general population screening guidelines...
On the development of a decision support intervention for mothers undergoing BRCA1/2 cancer genetic testing regarding communicating test results to their childrenBeth N Peshkin
Jess and Mildred Fisher Center for Familial Cancer Research, Cancer Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3300 Whitehaven Street, NW, Suite 4100, Washington, DC 20007 2401, USA
Fam Cancer 9:89-97. 2010....
Telephone genetic counseling for high-risk women undergoing BRCA1 and BRCA2 testing: rationale and development of a randomized controlled trialBeth N Peshkin
Lombardi Comprehensive Cancer Center, Jess and Mildred Fisher Center for Familial Cancer Research Georgetown University, Washington, District of Columbia 20007 2401, USA
Genet Test 12:37-52. 2008..In addition, procedural aspects of the genetic counseling intervention and the novel tools developed to facilitate this process and to ensure adequate counselor training and quality assurance are described...- BRCA1/2 mutations and triple negative breast cancersBeth N Peshkin
Fisher Center for Familial Cancer Research, Georgetown University, Lombardi Comprehensive Cancer Center, Washington, DC 20007 2401, USA
Breast Dis 32:25-33. 2010..Identifying women at increased risk is critical as knowledge of mutation status may impact surgical and systemic treatment in newly diagnosed patients, as well as recommendations for ovarian cancer risk management... - Tamoxifen as chemoprevention in BRCA1 and BRCA2 mutation carriers with breast cancer: a pilot survey of physiciansBeth N Peshkin
CGC, 2233 Wisconsin Ave, NW, Suite 317, Washington, DC 20007, USA
J Clin Oncol 21:4322-8. 2003..To assess physician recommendations about the use of tamoxifen in premenopausal BRCA1 and BRCA2 mutation carriers... - BRCA1/2 test results impact risk management attitudes, intentions, and uptakeSuzanne C O'Neill
Cancer Control Program and Fisher Center for Familial Cancer Research, Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA
Breast Cancer Res Treat 124:755-64. 2010..001). Receipt of BRCA1/2 mutation test results impacts how carriers see the positive aspects of RRO and RRM and their surgical intentions. Both the positive and negative aspects predict uptake of surgery... - Primary care providers' willingness to recommend BRCA1/2 testing to adolescentsSuzanne C O'Neill
Cancer Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3300 Whitehaven St, NW, Suite 4100, Washington, DC 20007, USA
Fam Cancer 9:43-50. 2010.... - Prevalence and correlates of mothers and fathers attending pretest cancer genetic counseling togetherTiffani A Demarco
Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3300 Whitehaven Street, NW, Suite 4100, Washington, DC, USA
Patient Educ Couns 78:29-33. 2010.... - Information needs of mothers regarding communicating BRCA1/2 cancer genetic test results to their childrenKenneth P Tercyak
Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007 2401, USA
Genet Test 11:249-55. 2007..In conjunction with enhanced genetic counseling focusing on family disclosure, educational literature, and psychosocial support may promote improved outcomes... - Randomized trial of a decision aid for BRCA1/BRCA2 mutation carriers: impact on measures of decision making and satisfactionMarc D Schwartz
Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA
Health Psychol 28:11-9. 2009..To help BRCA1/2 carriers make this decision, the authors developed a computer-based interactive decision aid that was tested against usual care in a randomized controlled trial... - Parenting through genetic uncertainty: themes in the disclosure of breast cancer risk information to childrenMcKane E Sharff
Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, District of Columbia, USA
Genet Test Mol Biomarkers 16:376-82. 2012..Among mothers undergoing BRCA1/2 testing and their spouses/partners, this study sought to examine decision support needs and motivations for family communication of genetic risk information to asymptomatic children... - Brief assessment of parents' attitudes toward testing minor children for hereditary breast/ovarian cancer genes: development and validation of the Pediatric BRCA1/2 Testing Attitudes Scale (P-TAS)Beth N Peshkin
Lombardi Comprehensive Cancer Center, USA
J Pediatr Psychol 34:627-38. 2009..The aim of this study was to develop and evaluate a new measure for use in genetic research and consultation, known as the Pediatric BRCA1/2 Testing Attitudes Scale (P-TAS)... - Long-term outcomes of BRCA1/BRCA2 testing: risk reduction and surveillanceMarc D Schwartz
Department of Oncology, Cancer Control Program, Jess and Mildred Fisher Center for Familial Cancer Research, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA
Cancer 118:510-7. 2012..We evaluated long-term uptake and predictors of risk-reducing mastectomy (RRM), risk-reducing bilateral salpingo-oophorectomy (RRBSO), chemoprevention, and cancer screening among women at a mean of 5.3 years after testing... - Longitudinal changes in patient distress following interactive decision aid use among BRCA1/2 carriers: a randomized trialGillian W Hooker
Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA
Med Decis Making 31:412-21. 2011..Individuals who are found to be carriers of a BRCA1 or BRCA2 mutation have a substantially elevated risk for breast cancer and are frequently faced with the decision of whether to undergo risk-reducing mastectomy... - Utilization of BRCA1/BRCA2 mutation testing in newly diagnosed breast cancer patientsMarc D Schwartz
Department of Oncology, Lombardi Comprehensive Cancer Center, Cancer Control Program, Georgetown University School of Medicine, Suite 317, 2233 Wisconsin Avenue, Northwest, Washington, DC 20007, USA
Cancer Epidemiol Biomarkers Prev 14:1003-7. 2005..In this study, we evaluated factors associated with the decision to undergo BRCA1/BRCA2 gene testing at the time of initial breast cancer diagnosis... - Quality of life after contralateral prophylactic mastectomy in newly diagnosed high-risk breast cancer patients who underwent BRCA1/2 gene testingKenneth P Tercyak
Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007 2401, USA
J Clin Oncol 25:285-91. 2007..In this study, we compared the impact of BRCA1/2 genetic test result and CPM on these outcomes among newly diagnosed breast cancer patients who opted for CPM at the time of their definitive surgical treatment versus patients who did not... - Predictors of participation in psychosocial telephone counseling following genetic testing for BRCA1 and BRCA2 mutationsChanita Hughes Halbert
Department of Psychiatry and Abramson Cancer Center, University of Pennsylvania, 3535 Market Street, Suite 4100, Philadelphia, PA 19104, USA
Cancer Epidemiol Biomarkers Prev 13:875-81. 2004.... - Impact of BRCA1/BRCA2 counseling and testing on newly diagnosed breast cancer patientsMarc D Schwartz
Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA
J Clin Oncol 22:1823-9. 2004..In the present study, we prospectively evaluated the impact on surgical decision-making of pretreatment genetic counseling and BRCA1/BRCA2 testing among breast cancer patients at high-risk for carrying a mutation... - Bilateral prophylactic oophorectomy and ovarian cancer screening following BRCA1/BRCA2 mutation testingMarc D Schwartz
Department of Oncology, Lombardi Cancer Center, Georgetown University, Washington, DC 20007, USA
J Clin Oncol 21:4034-41. 2003..In this study, we prospectively examined the impact of BRCA1/2 testing on the utilization of prophylactic oophorectomy and ovarian cancer screening. Participants and.. - Impact of BRCA1/BRCA2 mutation testing on psychologic distress in a clinic-based sampleMarc D Schwartz
Department of Oncology, Georgetown University, and Lombardi Cancer Center, Washington, DC 20007, USA
J Clin Oncol 20:514-20. 2002..The objective of this study was to examine the long-term psychologic impact of receiving BRCA1/2 test results within a clinic-based testing program... - Predictors and outcomes of contralateral prophylactic mastectomy among breast cancer survivorsKristi D Graves
Cancer Control Program, Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA
Breast Cancer Res Treat 104:321-9. 2007..To reduce the risk of contralateral breast cancer, some patients opt for prophylactic surgery of the unaffected breast (contralateral prophylactic mastectomy, CPM) in addition to mastectomy of the affected breast... - Randomized controlled trial of a psychosocial telephone counseling intervention in BRCA1 and BRCA2 mutation carriersKristi D Graves
Department of Oncology and The Fisher Centerfor Familial Cancer Research, Lombardi Comprehensive Cancer Center, Georgetown University, 3300 Whitehaven Street, Northwest, Suite 4100, Washington, DC 20007, USA
Cancer Epidemiol Biomarkers Prev 19:648-54. 2010..We examined the effect of the intervention on distress and the concerns related to genetic testing... - Decision making and decision support for hereditary breast-ovarian cancer susceptibilityMarc D Schwartz
Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA
Health Psychol 24:S78-84. 2005..In particular, the authors discuss the role of anxiety and worry in relation to testing and surgery decisions... - Outcomes of a systems-level intervention offering breast cancer risk assessments to low-income underserved womenDarren Mays
Division of Health Outcomes and Health Behaviors, Department of Oncology, Lombardi Comprehensive Cancer, Georgetown University Medical Center, 3300 Whitehaven Street, NW, Suite 4100, Washington, DC 20007, USA
Fam Cancer 11:493-502. 2012..More intensive patient navigation addressing the unique barriers encountered within this population may be required to enhance utilization... - Long-term psychosocial outcomes of BRCA1/BRCA2 testing: differences across affected status and risk-reducing surgery choiceKristi D Graves
Department of Oncology, Cancer Control Program, Breast Cancer Program, Jess and Mildred Fisher Center for Familial Cancer Research, Lombardi Comprehensive Cancer Center, Washington, District of Columbia 20007, USA
Cancer Epidemiol Biomarkers Prev 21:445-55. 2012..We conducted the first long-term prospective study of psychosocial outcomes in a U.S. sample of women who had BRCA1/2 testing... - Predictors of enrollment into a familial cancer registry by individuals at high risk for BRCA1/2Kristi D Graves
Cancer Control Program, Lombardi Comprehensive Cancer Center, Georgetown University, 3300 Whitehaven Street, Northwest, Suite 4100, Washington, DC 20007, USA
Cancer Epidemiol Biomarkers Prev 16:2763-7. 2007..We also sought to identify the factors associated with provision of a blood sample to the FCR... - Adolescent medical providers' willingness to recommend genetic susceptibility testing for nicotine addiction and lung cancer risk to adolescentsSuzanne C O'Neill
Cancer Control Program, Lombardi Comprehensive Cancer Center, Washington DC 20007, USA
J Pediatr Psychol 34:617-26. 2009..To examine the influences of disease, lifestyle, and other factors on adolescent medical providers' willingness to recommend genetic susceptibility testing (GST)... - Can a computer-based system be used to educate women on genetic testing for breast cancer susceptibility?Marc D Schwartz
Georgetown University School of Medicine, and Lombardi Comprehensive Cancer Center, Washington, DC 20007, USA
Nat Clin Pract Oncol 2:24-5. 2005 - Evaluation and management of women with BRCA1/2 mutationsBeth N Peshkin
Oncology and Medicine Department of Cancer Control, Georgetown University, Lombardi Comprehensive Cancer Center, Washington, DC, USA
Oncology (Williston Park) 19:1451-9; discussion 1459-68 1474. 2005..We conclude with a review and appraisal of the various options for breast and ovarian cancer risk reduction and screening options for women with a BRCA1 or BRCA2 mutation... - Breast and ovarian cancer screening practices in healthy women with a strong family history of breast or ovarian cancerClaudine Isaacs
Department of Medical Oncology, Lombardi Cancer Center, Georgetown University, Washington, DC 20007 2197, USA
Breast Cancer Res Treat 71:103-12. 2002..These findings indicate a need for better education about screening guidelines for high-risk women... - Women's satisfaction with genetic counseling for hereditary breast-ovarian cancer: psychological aspectsKenneth P Tercyak
Cancer Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, District of Columbia, USA
Am J Med Genet A 131:36-41. 2004..The implications for future research and clinical practice are discussed... - Practical aspects of delivering hereditary cancer risk counselingTiffani A Demarco
Jess and Mildred Fisher Center for Familial Cancer Research, Georgetown University, Lombardi Comprehensive Cancer Center, Washington, DC 20007, USA
Semin Oncol 34:369-78. 2007.... - Patterns and correlates of multiple risk factors for adult-onset cancer among adolescents(1)Darren Mays
Division of Health Outcomes and Health Behaviors, Department of Oncology, Georgetown University Medical Center, Washington, DC 20007, USA
J Child Health Care 16:250-62. 2012..05) associated with MCRFs. Multiple health behavior change interventions are needed to prevent accumulation of risk factors as youth mature. Self-efficacy may be an important target for prevention interventions... - Correlates of adherence to a telephone-based multiple health behavior change cancer preventive intervention for teens: the Healthy for Life Program (HELP)Darren Mays
Lombardi Comprehensive Cancer Center, Washington, DC, USA
Health Educ Behav 39:18-26. 2012..After adjusting for age, teens with poorer session engagement (e.g., less cooperative) completed fewer sessions (B = -1.97, p = .003, R (2) = .24). Implications for adolescent cancer prevention research are discussed... - Parent-child factors and their effect on communicating BRCA1/2 test results to childrenKenneth P Tercyak
Lombardi Cancer Center, Georgetown University Medical Center, 2233 Wisconsin Avenue, NW, Suite 317, Washington, DC 20007, USA
Patient Educ Couns 47:145-53. 2002.... - Role of parenting relationship quality in communicating about maternal BRCA1/2 genetic test results with childrenTiffani A Demarco
Cancer Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3300 Whitehaven Street, Washington, DC 20007, USA
J Genet Couns 17:283-7. 2008..Finally, this report addresses potential ways in which the genetic counselor may be able to facilitate parental communication regarding the evolving process of disclosure of genetic information to children and adolescents... - Interest in genetic counseling and testing for adolescent nicotine addiction susceptibility among a sample of adolescent medicine providers attending a scientific conference on adolescent healthKenneth P Tercyak
Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA
J Adolesc Health 41:42-50. 2007.... - Interest of adolescents in genetic testing for nicotine addiction susceptibilityKenneth P Tercyak
Cancer Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3300 Whitehaven Street, NW, Suite 4100, Washington, DC 20007 2401, USA
Prev Med 42:60-5. 2006..This paper examines adolescents' interest in, and reasons behind interest in, such testing and correlates of interest... - BRCA1/2 genetic testing uptake and psychosocial outcomes in menKristi D Graves
Cancer Control Program, Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, 3300 Whitehaven Street, Suite 4100, Washington, DC 20007, USA
Fam Cancer 10:213-23. 2011.... - Psychosocial and Quality of Life in Women Receiving the 21-Gene Recurrence Score Assay: The Impact of Decision Style in Women with Intermediate RSNadiyah Sulayman
Department of Oncology, The Fisher Center for Familial Cancer Research, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3300 Whitehaven Street, NW, Suite 4100, Washington, DC 20007, USA
J Cancer Epidemiol 2012:728290. 2012..These data should be confirmed in prospective samples, as these poorer outcomes could be amenable to intervention... - Providers' perceptions and practices regarding BRCA1/2 genetic counseling and testing in African American womenKristi D Graves
Lombardi Comprehensive Cancer Center, Cancer Control Program, Fisher Center for Familial Cancer Research, Georgetown University, Washington, DC 20007, USA
J Genet Couns 20:674-89. 2011..Results have implications for physician and patient education regarding appropriate referrals to and uptake of genetic services in at-risk African American women... - "Is it really worth it to get tested?": primary care patients' impressions of predictive SNP testing for colon cancerKara Grace Leventhal
Fisher Center for Familial Cancer Research, Lombardi Comprehensive Cancer Center, Georgetown University, 3300 Whitehaven Street, NW, Suite 4100, Washington, DC 20007, USA
J Genet Couns 22:138-51. 2013..These findings suggest that patients may look to genetic counselors, physicians or other healthcare professionals as gatekeepers of predictive genomic risk information... - Genetic discrimination in health insurance: current legal protections and industry practicesKaren Pollitz
Georgetown University Health Policy Institute, Washington, DC 20057, USA
Inquiry 44:350-68. 2007..In seven of these 92 applications, underwriters said they would deny coverage, place a surcharge on premiums,or limit covered benefits based on an applicant's genetic information... - All in the family: evaluation of the process and content of sisters' communication about BRCA1 and BRCA2 genetic test resultsChanita Hughes
Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Am J Med Genet 107:143-50. 2002.... - BRCAPRO validation, sensitivity of genetic testing of BRCA1/BRCA2, and prevalence of other breast cancer susceptibility genesDonald A Berry
Department of Biostatistics, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
J Clin Oncol 20:2701-12. 2002.... - Oophorectomy in carriers of BRCA mutationsBeth N Peshkin
N Engl J Med 347:1037-40; author reply 1037-40. 2002 - A brief assessment of concerns associated with genetic testing for cancer: the Multidimensional Impact of Cancer Risk Assessment (MICRA) questionnaireDavid Cella
Center on Outcomes Research and Education, Evanston Northwestern Healthcare, Illinois 60201, USA
Health Psychol 21:564-72. 2002..77), and Positive Experiences (4 items, alpha = .75). All 3 MICRA subscales differentiated participants who were BRCA1/2 positive from the other 3 groups. MICRA thus helps identify subgroups of vulnerable genetic testing participants... - Predictors of cognitive appraisals following genetic testing for BRCA1 and BRCA2 mutationsChanita Hughes Halbert
Department of Psychiatry and Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
J Behav Med 27:373-92. 2004..001). These results suggest that interventions designed to address perceptions of stress related to medical decision-making and familial concerns may need to be targeted to BRCA1/2 mutation carriers and individuals who are highly anxious... - Breast cancer risk assessment and genetic testing: complexities, conundrums, and communityBeth N Peshkin
Breast Dis 27:1-3. 2006 - Characterization of BRCA1 and BRCA2 mutations in a large United States sampleSining Chen
Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
J Clin Oncol 24:863-71. 2006..Existing studies have focused on Ashkenazi Jews (AJ) or on families from outside the United States. In this article, we consider the US population using the largest US-based cohort to date of both AJ and non-AJ families... - Genetic counseling about reproductive options for hereditary cancer: what is the standard of care?Beth N Peshkin
J Clin Oncol 25:911-2; author reply 913. 2007 - Validity of models for predicting BRCA1 and BRCA2 mutationsGiovanni Parmigiani
The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland 21205 2011, USA
Ann Intern Med 147:441-50. 2007..At least 7 models for estimating the probabilities of having a mutation are used widely in clinical and scientific activities; however, the merits and limitations of these models are not fully understood... - Tolerance for uncertainty and perceived risk among women receiving uninformative BRCA1/2 test resultsSuzanne C O'Neill
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Am J Med Genet C Semin Med Genet 142:251-9. 2006..The clinical and research implications of these results are discussed...
Research Grants
- BRCA1/2 Education for Mothers and Their Teen DaughtersBETH PESHKIN; Fiscal Year: 2006..It is expected that with respect to issues surrounding hereditary cancer susceptibility, the resource will result in improved knowledge, communication, and support among mothers and their teenage daughters. ..