Mikell Paige

Summary

Affiliation: Georgetown University
Country: USA

Publications

  1. pmc Pilot analysis of the plasma metabolite profiles associated with emphysematous Chronic Obstructive Pulmonary Disease phenotype
    Mikell Paige
    Georgetown University, Drug Discovery Program, Lombardi Comprehensive Cancer Center, 3970 Reservoir Road, NW, NRB EP15, Washington, DC 20057, USA
    Biochem Biophys Res Commun 413:588-93. 2011
  2. pmc ApoE mimetic peptide decreases Abeta production in vitro and in vivo
    S Sakura Minami
    Department of Neuroscience, Georgetown University, 3970 Reservoir Rd, NW, Washington, DC 20057, USA
    Mol Neurodegener 5:16. 2010
  3. pmc Effect of the leukotriene A4 hydrolase aminopeptidase augmentor 4-methoxydiphenylmethane in a pre-clinical model of pulmonary emphysema
    Eliseu O De Oliveira
    Georgetown University Medical Center, Lombardi Comprehensive Cancer Center, Washington, DC 20057, USA
    Bioorg Med Chem Lett 21:6746-50. 2011
  4. doi request reprint Design, synthesis and biological evaluation of ezrin inhibitors targeting metastatic osteosarcoma
    Mikell Paige
    George Mason University, Department of Chemistry and Biochemistry, 10900 University Blvd, MS 1A9, Manassas, VA 20110, USA Georgetown University Medical Center, Center for Drug Discovery, 3970 Reservoir Road, NW, The Research Building, Room EP07, Washington, DC 20057, USA Electronic address
    Bioorg Med Chem 22:478-87. 2014

Collaborators

  • Robert J Snelgrove
  • Eliseu O De Oliveira
  • S Sakura Minami
  • Kan Wang
  • Y Michael Shim
  • Hye Sik Kong
  • Suhyon Kim
  • Matthew Miessau
  • Sivanesan Dakshanamurthy
  • Joseph A Tesoriero
  • Antoinette Cordova
  • G William Rebeck
  • Gary C Davis
  • HYANG SOOK HOE
  • Daniel Ts Pak
  • Lenard W Babus
  • John R Cirrito
  • R Scott Turner

Detail Information

Publications4

  1. pmc Pilot analysis of the plasma metabolite profiles associated with emphysematous Chronic Obstructive Pulmonary Disease phenotype
    Mikell Paige
    Georgetown University, Drug Discovery Program, Lombardi Comprehensive Cancer Center, 3970 Reservoir Road, NW, NRB EP15, Washington, DC 20057, USA
    Biochem Biophys Res Commun 413:588-93. 2011
    ..These results also suggest that the metabolomics profiling could potentially guide the characterization of relevant metabolites that leads to an emphysematous COPD phenotype...
  2. pmc ApoE mimetic peptide decreases Abeta production in vitro and in vivo
    S Sakura Minami
    Department of Neuroscience, Georgetown University, 3970 Reservoir Rd, NW, Washington, DC 20057, USA
    Mol Neurodegener 5:16. 2010
    ..Here, we further examined whether peptides containing tandem repeats of the apoE receptor-binding region (amino acids 141-149) affected APP trafficking, APP processing, and Abeta production...
  3. pmc Effect of the leukotriene A4 hydrolase aminopeptidase augmentor 4-methoxydiphenylmethane in a pre-clinical model of pulmonary emphysema
    Eliseu O De Oliveira
    Georgetown University Medical Center, Lombardi Comprehensive Cancer Center, Washington, DC 20057, USA
    Bioorg Med Chem Lett 21:6746-50. 2011
    ..Pre-clinical evaluation of our drug showed protection against intranasal elastase-induced pulmonary emphysema in murine models...
  4. doi request reprint Design, synthesis and biological evaluation of ezrin inhibitors targeting metastatic osteosarcoma
    Mikell Paige
    George Mason University, Department of Chemistry and Biochemistry, 10900 University Blvd, MS 1A9, Manassas, VA 20110, USA Georgetown University Medical Center, Center for Drug Discovery, 3970 Reservoir Road, NW, The Research Building, Room EP07, Washington, DC 20057, USA Electronic address
    Bioorg Med Chem 22:478-87. 2014
    ..Optimization of a series of heterocyclic-dione analogues led to the discovery of compounds 21k and 21m as potential novel antimetastatic agents. ..