DONALD JOHN MASSARO

Summary

Affiliation: Georgetown University
Country: USA

Publications

  1. ncbi request reprint Invited Review: pulmonary alveoli: formation, the "call for oxygen," and other regulators
    Donald Massaro
    Lung Biology Laboratory, Department of Medicine, Georgetown University School of Medicine, Washington, District of Columbia 20007 2197, USA
    Am J Physiol Lung Cell Mol Physiol 282:L345-58. 2002
  2. doi request reprint Apoetm1Unc mice have impaired alveologenesis, low lung function, and rapid loss of lung function
    Donald Massaro
    Department of Medicine, Lung Regeneration Laboratory, Georgetown Univ School of Medicine, 3900 Reservoir Rd NW, Washington, DC 20057 1481, USA
    Am J Physiol Lung Cell Mol Physiol 294:L991-7. 2008
  3. ncbi request reprint Estrogen receptor-alpha regulates pulmonary alveolar loss and regeneration in female mice: morphometric and gene expression studies
    Donald Massaro
    Lung Regeneration Laboratory, Department of Medicine, Georgetown University School of Medicine, Washington, District of Columbia 20057 1481, USA
    Am J Physiol Lung Cell Mol Physiol 293:L222-8. 2007
  4. ncbi request reprint Rapid onset of gene expression in lung, supportive of formation of alveolar septa, induced by refeeding mice after calorie restriction
    Donald Massaro
    Lung Regeneration Laboratory, Department of 1Medicine, Georgetown University School of Medicine, Children s National Medical Center, Washington, District of Columbia 20057 1481, USA
    Am J Physiol Lung Cell Mol Physiol 292:L1313-26. 2007
  5. pmc Toward therapeutic pulmonary alveolar regeneration in humans
    Donald Massaro
    Lung Biology Laboratory, Box 571481, Georgetown University School of Medicine, 3900 Reservoir Road, NW, Washington, DC 20057 1481, USA
    Proc Am Thorac Soc 3:709-12. 2006
  6. ncbi request reprint Estrogen receptor regulation of pulmonary alveolar dimensions: alveolar sexual dimorphism in mice
    Donald Massaro
    Lung Biology Laboratory, Preclinical Science Building GM 12, Georgetown University School of Medicine, 3900 Reservoir Road NW, Washington, DC 20057 1481, USA
    Am J Physiol Lung Cell Mol Physiol 290:L866-70. 2006
  7. ncbi request reprint Estrogen regulates pulmonary alveolar formation, loss, and regeneration in mice
    Donald Massaro
    Lung Biology Laboratory, Department of Medicine, Georgetown University School of Medicine, 3900 Reservoir Road, NW, Washington, DC 20057 1481, USA
    Am J Physiol Lung Cell Mol Physiol 287:L1154-9. 2004
  8. ncbi request reprint Noninvasive delivery of small inhibitory RNA and other reagents to pulmonary alveoli in mice
    Donald Massaro
    Lung Biology Laboratory, Department of Medicine, Georgetown University School of Medicine, Washington, District of Columbia 20057 1481, USA
    Am J Physiol Lung Cell Mol Physiol 287:L1066-70. 2004
  9. ncbi request reprint Calorie-related rapid onset of alveolar loss, regeneration, and changes in mouse lung gene expression
    Donald Massaro
    Lung Biology Laboratory, Box 571481, Preclinical Science Bldg, GM 12, Georgetown Univ School of Medicine, 3900 Reservoir Road, NW, Washington, DC 20057 1481
    Am J Physiol Lung Cell Mol Physiol 286:L896-906. 2004
  10. ncbi request reprint Retinoids, alveolus formation, and alveolar deficiency: clinical implications
    Donald Massaro
    Department of Medicine, Lung Biology Laboratory, Georgetown University School of Medicine, Washington, District of Columbia 20057, USA
    Am J Respir Cell Mol Biol 28:271-4. 2003

Research Grants

  1. ALVEOLUS FORMATION--MORPHOMETRIC AND MOLECULAR STUDIES
    Donald Massaro; Fiscal Year: 2003
  2. Alveolar turnover:formation and loss
    Donald Massaro; Fiscal Year: 2007
  3. Experimental COPD: remediation, mitigation
    DONALD JOHN MASSARO; Fiscal Year: 2010
  4. Alveolar Biology: Sex, Age, and Alveolar Turnover
    Donald Massaro; Fiscal Year: 2007
  5. REMEDIATION OF EMPHYSEMA--MECHANISMS, CHARACTERISTICS
    Donald Massaro; Fiscal Year: 2001
  6. EXPERIMENTAL EMPHYSEMA--STUDIES ON REMEDIATION
    Donald Massaro; Fiscal Year: 2001

Detail Information

Publications11

  1. ncbi request reprint Invited Review: pulmonary alveoli: formation, the "call for oxygen," and other regulators
    Donald Massaro
    Lung Biology Laboratory, Department of Medicine, Georgetown University School of Medicine, Washington, District of Columbia 20007 2197, USA
    Am J Physiol Lung Cell Mol Physiol 282:L345-58. 2002
    ..Thus there is a complex, fascinating, but poorly understood, signaling relationship among VO(2), the neural regulation of breathing, and lung architecture, composition, and mechanics...
  2. doi request reprint Apoetm1Unc mice have impaired alveologenesis, low lung function, and rapid loss of lung function
    Donald Massaro
    Department of Medicine, Lung Regeneration Laboratory, Georgetown Univ School of Medicine, 3900 Reservoir Rd NW, Washington, DC 20057 1481, USA
    Am J Physiol Lung Cell Mol Physiol 294:L991-7. 2008
    ....
  3. ncbi request reprint Estrogen receptor-alpha regulates pulmonary alveolar loss and regeneration in female mice: morphometric and gene expression studies
    Donald Massaro
    Lung Regeneration Laboratory, Department of Medicine, Georgetown University School of Medicine, Washington, District of Columbia 20057 1481, USA
    Am J Physiol Lung Cell Mol Physiol 293:L222-8. 2007
    ....
  4. ncbi request reprint Rapid onset of gene expression in lung, supportive of formation of alveolar septa, induced by refeeding mice after calorie restriction
    Donald Massaro
    Lung Regeneration Laboratory, Department of 1Medicine, Georgetown University School of Medicine, Children s National Medical Center, Washington, District of Columbia 20057 1481, USA
    Am J Physiol Lung Cell Mol Physiol 292:L1313-26. 2007
    ..These findings identify the first hour after providing calorie-restricted mice ad libitum access to food as the onset of gene expression in this model that supports processes needed for alveolar regeneration...
  5. pmc Toward therapeutic pulmonary alveolar regeneration in humans
    Donald Massaro
    Lung Biology Laboratory, Box 571481, Georgetown University School of Medicine, 3900 Reservoir Road, NW, Washington, DC 20057 1481, USA
    Proc Am Thorac Soc 3:709-12. 2006
    ..We review animal models of alveolar loss and regeneration and their conservation during evolution, and hence their relevance to humans...
  6. ncbi request reprint Estrogen receptor regulation of pulmonary alveolar dimensions: alveolar sexual dimorphism in mice
    Donald Massaro
    Lung Biology Laboratory, Preclinical Science Building GM 12, Georgetown University School of Medicine, 3900 Reservoir Road NW, Washington, DC 20057 1481, USA
    Am J Physiol Lung Cell Mol Physiol 290:L866-70. 2006
    ....
  7. ncbi request reprint Estrogen regulates pulmonary alveolar formation, loss, and regeneration in mice
    Donald Massaro
    Lung Biology Laboratory, Department of Medicine, Georgetown University School of Medicine, 3900 Reservoir Road, NW, Washington, DC 20057 1481, USA
    Am J Physiol Lung Cell Mol Physiol 287:L1154-9. 2004
    ....
  8. ncbi request reprint Noninvasive delivery of small inhibitory RNA and other reagents to pulmonary alveoli in mice
    Donald Massaro
    Lung Biology Laboratory, Department of Medicine, Georgetown University School of Medicine, Washington, District of Columbia 20057 1481, USA
    Am J Physiol Lung Cell Mol Physiol 287:L1066-70. 2004
    ..This simple noninvasive technique allows regulation of specific proteins in the lung and lung-specific delivery of reagents of experimental and potentially therapeutic importance...
  9. ncbi request reprint Calorie-related rapid onset of alveolar loss, regeneration, and changes in mouse lung gene expression
    Donald Massaro
    Lung Biology Laboratory, Box 571481, Preclinical Science Bldg, GM 12, Georgetown Univ School of Medicine, 3900 Reservoir Road, NW, Washington, DC 20057 1481
    Am J Physiol Lung Cell Mol Physiol 286:L896-906. 2004
    ..The evidence of involvement of CTLs and NK cells and the absence of necrosis are similar to alveolar destruction in chronic obstructive pulmonary disease...
  10. ncbi request reprint Retinoids, alveolus formation, and alveolar deficiency: clinical implications
    Donald Massaro
    Department of Medicine, Lung Biology Laboratory, Georgetown University School of Medicine, Washington, District of Columbia 20057, USA
    Am J Respir Cell Mol Biol 28:271-4. 2003
  11. doi request reprint Developmental alveologenesis: new roles for ApoE and LDL receptor
    Donald Massaro
    Department of Medicine, Georgetown University School of Medicine, Washington, District of Columbia 20057, USA
    Pediatr Res 70:458-61. 2011
    ....

Research Grants26

  1. ALVEOLUS FORMATION--MORPHOMETRIC AND MOLECULAR STUDIES
    Donald Massaro; Fiscal Year: 2003
    ..abstract_text> ..
  2. Alveolar turnover:formation and loss
    Donald Massaro; Fiscal Year: 2007
    ..abstract_text> ..
  3. Experimental COPD: remediation, mitigation
    DONALD JOHN MASSARO; Fiscal Year: 2010
    ..There is not treatment that slows the relentless progression of the disease or that reverses it. In this application, we use an animal model to investigate methods to slow progression and reverse the disease. ..
  4. Alveolar Biology: Sex, Age, and Alveolar Turnover
    Donald Massaro; Fiscal Year: 2007
    ..abstract_text> ..
  5. REMEDIATION OF EMPHYSEMA--MECHANISMS, CHARACTERISTICS
    Donald Massaro; Fiscal Year: 2001
    ....
  6. EXPERIMENTAL EMPHYSEMA--STUDIES ON REMEDIATION
    Donald Massaro; Fiscal Year: 2001
    ....