L Malkova

Summary

Affiliation: Georgetown University
Country: USA

Publications

  1. ncbi request reprint MRI-Based evaluation of locus and extent of neurotoxic lesions in monkeys
    L Malkova
    Department of Pharmacology, Georgetown University Medical Center, Washington, DC, USA
    Hippocampus 11:361-70. 2001
  2. ncbi request reprint One-trial memory for object-place associations after separate lesions of hippocampus and posterior parahippocampal region in the monkey
    Ludise Malkova
    Department of Pharmacology, Georgetown University Medical Center, Washington, DC 20007, USA
    J Neurosci 23:1956-65. 2003
  3. ncbi request reprint Longitudinal magnetic resonance imaging study of rhesus monkey brain development
    L Malkova
    Department of Pharmacology, Georgetown University, 900 Reservoir Road, Washington, DC 20007, USA
    Eur J Neurosci 24:3204-12. 2006
  4. pmc Long-term effects of neonatal medial temporal ablations on socioemotional behavior in monkeys (Macaca mulatta)
    Ludise Malkova
    National Institute of Mental Health, Bethesda, Maryland, USA
    Behav Neurosci 124:742-60. 2010
  5. pmc The effects of huperzine A and IDRA 21 on visual recognition memory in young macaques
    Ludise Malkova
    Department of Pharmacology and the Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, 3900 Reservoir Rd NW, Washington, DC 20007, USA
    Neuropharmacology 60:1262-8. 2011
  6. ncbi request reprint Neurotoxic lesions of perirhinal cortex impair visual recognition memory in rhesus monkeys
    L Malkova
    Department of Pharmacology, Georgetown University Medical Center, W217 TRB 3950 Reservoir Rd NW, Washington, DC 20007, USA
    Neuroreport 12:1913-7. 2001
  7. ncbi request reprint Effects of aspiration versus neurotoxic lesions of the amygdala on emotional responses in monkeys
    M Meunier
    Laboratory of Neuropsychology, National Institute of Mental Health, Bethesda, MD, USA
    Eur J Neurosci 11:4403-18. 1999
  8. pmc A visual, position-independent instrumental reinforcer devaluation task for rats
    Elizabeth A West
    Interdisciplinary Program in Neuroscience, Georgetown University, 3970 Reservoir Rd NW, Washington, DC 20007, United States
    J Neurosci Methods 194:297-304. 2011
  9. ncbi request reprint Effects of hippocampal lesions on the monkey's ability to learn large sets of object-place associations
    Annabelle M Belcher
    Laboratory of Neuropsychology, NIMH, NIH, Bethesda, Maryland 20892, USA
    Hippocampus 16:361-7. 2006

Research Grants

Collaborators

Detail Information

Publications9

  1. ncbi request reprint MRI-Based evaluation of locus and extent of neurotoxic lesions in monkeys
    L Malkova
    Department of Pharmacology, Georgetown University Medical Center, Washington, DC, USA
    Hippocampus 11:361-70. 2001
    ..These MRI-based methods thus provide an accurate in vivo evaluation of the locus and extent of neurotoxic lesions. Application of these methods can ensure that each animal in the experiment is used effectively...
  2. ncbi request reprint One-trial memory for object-place associations after separate lesions of hippocampus and posterior parahippocampal region in the monkey
    Ludise Malkova
    Department of Pharmacology, Georgetown University Medical Center, Washington, DC 20007, USA
    J Neurosci 23:1956-65. 2003
    ....
  3. ncbi request reprint Longitudinal magnetic resonance imaging study of rhesus monkey brain development
    L Malkova
    Department of Pharmacology, Georgetown University, 900 Reservoir Road, Washington, DC 20007, USA
    Eur J Neurosci 24:3204-12. 2006
    ..The most rapid growth in both total brain volume and white matter from birth to approximately 4 months is consistent with the emergence of various cognitive abilities in macaques at that age...
  4. pmc Long-term effects of neonatal medial temporal ablations on socioemotional behavior in monkeys (Macaca mulatta)
    Ludise Malkova
    National Institute of Mental Health, Bethesda, Maryland, USA
    Behav Neurosci 124:742-60. 2010
    ..The finding that neonatal AH lesions produce more severe socioemotional disturbances than the same lesion in adulthood is the reverse of the effect commonly reported for other cognitive functions after cerebral damage...
  5. pmc The effects of huperzine A and IDRA 21 on visual recognition memory in young macaques
    Ludise Malkova
    Department of Pharmacology and the Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, 3900 Reservoir Rd NW, Washington, DC 20007, USA
    Neuropharmacology 60:1262-8. 2011
    ..This finding supports the potential use of this drug in treatment of cognitive and memory disorders. This article is part of a Special Issue entitled 'Trends in neuropharmacology: in memory of Erminio Costa'...
  6. ncbi request reprint Neurotoxic lesions of perirhinal cortex impair visual recognition memory in rhesus monkeys
    L Malkova
    Department of Pharmacology, Georgetown University Medical Center, W217 TRB 3950 Reservoir Rd NW, Washington, DC 20007, USA
    Neuroreport 12:1913-7. 2001
    ..The finding demonstrates that damage limited to perirhinal neurons is sufficient to impair visual memory and that damage to fibers of passage neither caused nor exacerbated the effect described initially...
  7. ncbi request reprint Effects of aspiration versus neurotoxic lesions of the amygdala on emotional responses in monkeys
    M Meunier
    Laboratory of Neuropsychology, National Institute of Mental Health, Bethesda, MD, USA
    Eur J Neurosci 11:4403-18. 1999
    ....
  8. pmc A visual, position-independent instrumental reinforcer devaluation task for rats
    Elizabeth A West
    Interdisciplinary Program in Neuroscience, Georgetown University, 3970 Reservoir Rd NW, Washington, DC 20007, United States
    J Neurosci Methods 194:297-304. 2011
    ..Discrimination of the visual cues is not aided by spatial cues, thereby eliminating a major difference between the instrumental tasks used in rats and the task used in monkeys...
  9. ncbi request reprint Effects of hippocampal lesions on the monkey's ability to learn large sets of object-place associations
    Annabelle M Belcher
    Laboratory of Neuropsychology, NIMH, NIH, Bethesda, Maryland 20892, USA
    Hippocampus 16:361-7. 2006
    ....

Research Grants6

  1. Neural Substrates /Socioemotional Disturbances /Develop.
    Ludise Malkova; Fiscal Year: 2003
    ..This information will provide a rationale basis for the design of therapeutic interventions directed at correcting the underlying biological dysfunctions that give rise to autism and related socioemotional disorders. ..
  2. Neural Substrates of Socioemotional Development
    Ludise Malkova; Fiscal Year: 2007
    ..Structured activities and short courses will guide the development of expertise in these areas necessary for the proposed studies as well as for the long-term career advancement of the candidate as a versatile neuroscientist. ..
  3. Seizures & Amydala-Based Socioemotional Dysfunction
    Ludise Malkova; Fiscal Year: 2007
    ..The team is ideally suited to approach the analysis of comorbidity of seizures and autistic-like symptoms evoked from amygdala and to permit a translationally meaningful analysis of the animal data. ..
  4. Socioemotional Behavior and Amygdala-Based Circuitry in Primates
    Ludise Malkova; Fiscal Year: 2010
    ..abstract_text> ..