Minetta C Liu

Summary

Affiliation: Georgetown University
Country: USA

Publications

  1. ncbi Circulating tumor cells: a useful predictor of treatment efficacy in metastatic breast cancer
    Minetta C Liu
    Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007 2198, USA
    J Clin Oncol 27:5153-9. 2009
  2. ncbi Novel strategies in cancer therapeutics: targeting enzymes involved in cell cycle regulation and cellular proliferation
    M C Liu
    Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3800 Reservoir Rd NW, Washington, DC 20007, USA
    Curr Cancer Drug Targets 4:403-24. 2004
  3. ncbi Dose-escalation of filgrastim does not improve efficacy: clinical tolerability and long-term follow-up on CALGB study 9141 adjuvant chemotherapy for node-positive breast cancer patients using dose-intensified doxorubicin plus cyclophosphamide followed by
    Minetta C Liu
    Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3800 Reservoir Road NW, Washington, DC 20007 2198, USA
    Cancer Treat Rev 34:223-30. 2008
  4. ncbi Gene network signaling in hormone responsiveness modifies apoptosis and autophagy in breast cancer cells
    Robert Clarke
    Department of Oncology and Lombardi Comprehensive Cancer Center, Georgetown University School of Medicine, Washington, DC 20057, USA
    J Steroid Biochem Mol Biol 114:8-20. 2009
  5. ncbi Phase I/II study of sorafenib with anastrozole in patients with hormone receptor positive aromatase inhibitor resistant metastatic breast cancer
    Claudine Isaacs
    Lombardi Comprehensive Cancer Center, Georgetown University, 3800 Reservoir Road, Washington, DC 20057, USA
    Breast Cancer Res Treat 125:137-43. 2011
  6. ncbi Antiestrogens, aromatase inhibitors, and apoptosis in breast cancer
    Rebecca B Riggins
    Department of Oncology and Physiology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA
    Vitam Horm 71:201-37. 2005
  7. ncbi Estrogen receptor alpha positive breast tumors and breast cancer cell lines share similarities in their transcriptome data structures
    Yuelin Zhu
    Lombardi Comprehensive Cancer Center and Departments of Oncology, Georgetown University School of Medicine, Washington, DC, USA
    Int J Oncol 29:1581-9. 2006
  8. ncbi The properties of high-dimensional data spaces: implications for exploring gene and protein expression data
    Robert Clarke
    Department of Oncology and Lombardi Comprehensive Cancer Center, Georgetown University School of Medicine, 3970 Reservoir Road NW, Washington, DC 20057, USA
    Nat Rev Cancer 8:37-49. 2008
  9. ncbi Caveolin-1 tyrosine phosphorylation enhances paclitaxel-mediated cytotoxicity
    Ayesha N Shajahan
    Department of Oncology, Lombardi Comprehensive Cancer Center, and Departments of Physiology and Biophysics, Georgetown University, College of Medicine, Washington, D C 20057, USA
    J Biol Chem 282:5934-43. 2007
  10. ncbi P53 gene mutations: case study of a clinical marker for solid tumors
    Minetta C Liu
    Department of Oncology, Lombardi Cancer Center, Georgetown University School of Medicine, Washington, DC 20007, USA
    Semin Oncol 29:246-57. 2002

Detail Information

Publications13

  1. ncbi Circulating tumor cells: a useful predictor of treatment efficacy in metastatic breast cancer
    Minetta C Liu
    Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007 2198, USA
    J Clin Oncol 27:5153-9. 2009
    ..We conducted a prospective study to demonstrate that CTC results correlate strongly with radiographic disease progression at the time of and in advance of imaging...
  2. ncbi Novel strategies in cancer therapeutics: targeting enzymes involved in cell cycle regulation and cellular proliferation
    M C Liu
    Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3800 Reservoir Rd NW, Washington, DC 20007, USA
    Curr Cancer Drug Targets 4:403-24. 2004
    ....
  3. ncbi Dose-escalation of filgrastim does not improve efficacy: clinical tolerability and long-term follow-up on CALGB study 9141 adjuvant chemotherapy for node-positive breast cancer patients using dose-intensified doxorubicin plus cyclophosphamide followed by
    Minetta C Liu
    Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3800 Reservoir Road NW, Washington, DC 20007 2198, USA
    Cancer Treat Rev 34:223-30. 2008
    ..A secondary aim was to assess if a higher dose (10 mcg/kg/day) of G-CSF is more efficacious than the conventional dose (5 mcg/kg/day) in this setting...
  4. ncbi Gene network signaling in hormone responsiveness modifies apoptosis and autophagy in breast cancer cells
    Robert Clarke
    Department of Oncology and Lombardi Comprehensive Cancer Center, Georgetown University School of Medicine, Washington, DC 20057, USA
    J Steroid Biochem Mol Biol 114:8-20. 2009
    ..Signaling proceeds through BCL2 gene family members and BECN1 ultimately to regulate cell fate...
  5. ncbi Phase I/II study of sorafenib with anastrozole in patients with hormone receptor positive aromatase inhibitor resistant metastatic breast cancer
    Claudine Isaacs
    Lombardi Comprehensive Cancer Center, Georgetown University, 3800 Reservoir Road, Washington, DC 20057, USA
    Breast Cancer Res Treat 125:137-43. 2011
    ..Toxicities occurred frequently resulting in a high rate of discontinuation...
  6. ncbi Antiestrogens, aromatase inhibitors, and apoptosis in breast cancer
    Rebecca B Riggins
    Department of Oncology and Physiology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA
    Vitam Horm 71:201-37. 2005
    ..Finally, we discuss the evidence supporting a role for apoptotic defects in acquired and de novo antiestrogen resistance...
  7. ncbi Estrogen receptor alpha positive breast tumors and breast cancer cell lines share similarities in their transcriptome data structures
    Yuelin Zhu
    Lombardi Comprehensive Cancer Center and Departments of Oncology, Georgetown University School of Medicine, Washington, DC, USA
    Int J Oncol 29:1581-9. 2006
    ....
  8. ncbi The properties of high-dimensional data spaces: implications for exploring gene and protein expression data
    Robert Clarke
    Department of Oncology and Lombardi Comprehensive Cancer Center, Georgetown University School of Medicine, 3970 Reservoir Road NW, Washington, DC 20057, USA
    Nat Rev Cancer 8:37-49. 2008
    ..From the perspective of translational science, this Review discusses the properties of high-dimensional data spaces that arise in genomic and proteomic studies and the challenges they can pose for data analysis and interpretation...
  9. ncbi Caveolin-1 tyrosine phosphorylation enhances paclitaxel-mediated cytotoxicity
    Ayesha N Shajahan
    Department of Oncology, Lombardi Comprehensive Cancer Center, and Departments of Physiology and Biophysics, Georgetown University, College of Medicine, Washington, D C 20057, USA
    J Biol Chem 282:5934-43. 2007
    ..Collectively, our findings underscore the importance of CAV1 phosphorylation in apoptosis and suggest that events that negate CAV1 tyrosine phosphorylation may contribute to anti-microtubule drug resistance...
  10. ncbi P53 gene mutations: case study of a clinical marker for solid tumors
    Minetta C Liu
    Department of Oncology, Lombardi Cancer Center, Georgetown University School of Medicine, Washington, DC 20007, USA
    Semin Oncol 29:246-57. 2002
    ....
  11. ncbi Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling
    Robert Clarke
    Department of Oncology and Vincent T Lombardi Cancer Center, Georgetown University School of Medicine, 3970 Reservoir Road NW, Washington, DC 20057, USA
    Oncogene 22:7316-39. 2003
    ..The network also may involve signaling through ras and MAPK, implicating crosstalk with growth factors and cytokines. Ultimately, signaling affects the expression/function of the proliferation and/or apoptotic machineries...
  12. ncbi Real-time imaging and characterization of human breast tissue by reflectance confocal microscopy
    Maddalena T Tilli
    Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USA
    J Biomed Opt 12:051901. 2007
    ..RCM data are comparable to data from H and E sections. Epithelial cell nuclear size is measured on stored digital RCM images. We compare RCM and H and E images from 16 patients and 25 core needle biopsy samples...
  13. ncbi Phase II trial of lapatinib for brain metastases in patients with human epidermal growth factor receptor 2-positive breast cancer
    Nancy U Lin
    Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    J Clin Oncol 26:1993-9. 2008
    ..We evaluated the safety and efficacy of lapatinib, an oral inhibitor of epidermal growth factor receptor (EGFR) and HER-2, in patients with HER-2-positive brain metastases...