Michael S Lipkowitz

Summary

Affiliation: Georgetown University
Country: USA

Publications

  1. pmc Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans
    Michael S Lipkowitz
    Division of Nephrology and Hypertension, Department of Medicine, Georgetown University School of Medicine, Washington, DC, USA
    Kidney Int 83:114-20. 2013
  2. doi Regulation of uric acid excretion by the kidney
    Michael S Lipkowitz
    Nephrology and Hypertension, Georgetown University Medical Center, Washington, DC 20007, USA
    Curr Rheumatol Rep 14:179-88. 2012
  3. pmc Common charge-shift mutation Glu65Lys in K+ channel β₁-Subunit KCNMB1: pleiotropic consequences for glomerular filtration rate and progressive renal disease
    Yuqing Chen
    Department of Medicine, University of California at San Diego, Calif, USA
    Am J Nephrol 32:414-24. 2010
  4. pmc Methylenetetrahydrofolate reductase (MTHFR) polymorphism A1298C (Glu429Ala) predicts decline in renal function over time in the African-American Study of Kidney Disease and Hypertension (AASK) Trial and Veterans Affairs Hypertension Cohort (VAHC)
    Maple M Fung
    Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA
    Nephrol Dial Transplant 27:197-205. 2012
  5. ncbi Galectin 9 is the sugar-regulated urate transporter/channel UAT
    Michael S Lipkowitz
    Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Glycoconj J 19:491-8. 2004
  6. ncbi Uric acid transport
    Mohammed A Rafey
    Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Curr Opin Nephrol Hypertens 12:511-6. 2003
  7. pmc Adrenergic beta-1 receptor genetic variation predicts longitudinal rate of GFR decline in hypertensive nephrosclerosis
    Maple M Fung
    Department of Medicine, University of California, San Diego, and San Diego Veterans Affairs Healthcare System, La Jolla, CA, USA
    Nephrol Dial Transplant 24:3677-86. 2009
  8. doi Association of phosphodiesterase 4 polymorphism (rs702553) with blood pressure in the African American Study of Kidney Disease and Hypertension Genomics Study
    Ericha G Anthony
    Graduate School of Public Health, San Diego State University, San Diego, California, USA
    Pharmacogenet Genomics 23:442-4. 2013
  9. ncbi Functional analysis and molecular model of the human urate transporter/channel, hUAT
    Edgar Leal-Pinto
    Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, New York, 10029, USA
    Am J Physiol Renal Physiol 283:F150-63. 2002

Collaborators

Detail Information

Publications9

  1. pmc Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans
    Michael S Lipkowitz
    Division of Nephrology and Hypertension, Department of Medicine, Georgetown University School of Medicine, Washington, DC, USA
    Kidney Int 83:114-20. 2013
    ..APOL1 risk variants were consistently associated with renal disease progression across medication classes and blood pressure targets. Thus, kidney disease in AASK participants was strongly associated with APOL1 renal risk variants...
  2. doi Regulation of uric acid excretion by the kidney
    Michael S Lipkowitz
    Nephrology and Hypertension, Georgetown University Medical Center, Washington, DC 20007, USA
    Curr Rheumatol Rep 14:179-88. 2012
    ..In the end, several of these clinical findings are explained, and the remaining gaps in our knowledge will become evident...
  3. pmc Common charge-shift mutation Glu65Lys in K+ channel β₁-Subunit KCNMB1: pleiotropic consequences for glomerular filtration rate and progressive renal disease
    Yuqing Chen
    Department of Medicine, University of California at San Diego, Calif, USA
    Am J Nephrol 32:414-24. 2010
    ..Here we asked whether the Glu65Lys variant influences GFR, in the basal state or during progressive renal decline...
  4. pmc Methylenetetrahydrofolate reductase (MTHFR) polymorphism A1298C (Glu429Ala) predicts decline in renal function over time in the African-American Study of Kidney Disease and Hypertension (AASK) Trial and Veterans Affairs Hypertension Cohort (VAHC)
    Maple M Fung
    Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA
    Nephrol Dial Transplant 27:197-205. 2012
    ..Here, we evaluated the influence of MTHFR variants on progressive loss of kidney function...
  5. ncbi Galectin 9 is the sugar-regulated urate transporter/channel UAT
    Michael S Lipkowitz
    Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Glycoconj J 19:491-8. 2004
    ..Finally, the presence and possible functions of at least 4 isoforms of UAT and a closely related gene hUAT2 are discussed...
  6. ncbi Uric acid transport
    Mohammed A Rafey
    Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Curr Opin Nephrol Hypertens 12:511-6. 2003
    ..The goal of this article is to review the physiology and describe newly defined molecular mechanisms that are responsible for renal urate transport...
  7. pmc Adrenergic beta-1 receptor genetic variation predicts longitudinal rate of GFR decline in hypertensive nephrosclerosis
    Maple M Fung
    Department of Medicine, University of California, San Diego, and San Diego Veterans Affairs Healthcare System, La Jolla, CA, USA
    Nephrol Dial Transplant 24:3677-86. 2009
    ..End-stage renal disease (ESRD) due to hypertension is common and displays familial aggregation in African Americans, suggesting genetic risk factors, including adrenergic activity alterations which are noted in both hypertension and ESRD...
  8. doi Association of phosphodiesterase 4 polymorphism (rs702553) with blood pressure in the African American Study of Kidney Disease and Hypertension Genomics Study
    Ericha G Anthony
    Graduate School of Public Health, San Diego State University, San Diego, California, USA
    Pharmacogenet Genomics 23:442-4. 2013
    ..Additional clinical and in-vitro studies are needed to better understand the biological mechanisms from gene expression to enzyme translation that affect blood pressure. ..
  9. ncbi Functional analysis and molecular model of the human urate transporter/channel, hUAT
    Edgar Leal-Pinto
    Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, New York, 10029, USA
    Am J Physiol Renal Physiol 283:F150-63. 2002
    ..These differences suggest that evolutionary changes in specific amino acids in these highly homologous proteins are functionally relevant in defining these biophysical properties...