Research Topics
| Zhang Zhi HuSummaryAffiliation: Georgetown University Country: USA Publications
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Detail Information
Publications
Literature mining and database annotation of protein phosphorylation using a rule-based systemZ Z Hu
Department of Biochemistry and Molecular Biology, Georgetown University Medical Center, Washington, DC 20057, USA
Bioinformatics 21:2759-65. 2005..9 and 88.0% for extraction of substrates and sites. Coupling the high recall for paper retrieval and high precision for information extraction, RLIMS-P facilitates literature mining and database annotation of protein phosphorylation...
Omics-based molecular target and biomarker identificationZhang Zhi Hu
Lombardi Cancer Center, Georgetown University, Washington, DC, USA
Methods Mol Biol 719:547-71. 2011..We describe a downstream workflow and procedures for functional analysis that focus on biological pathways, from which molecular targets can be derived and proposed for experimental validation...
Framework for a protein ontologyDarren A Natale
Department of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, 3300 Whitehaven St, NW, Washington, DC 20007, USA
BMC Bioinformatics 8:S1. 2007..Here we describe the initial development of PRO, illustrated using human and mouse proteins involved in the transforming growth factor-beta and bone morphogenetic protein signaling pathways...
DynGO: a tool for visualizing and mining of Gene Ontology and its associationsHongfang Liu
Department of Information Systems, University of Maryland, Baltimore County, 1000 Hilltop Circle, MD 21050, USA
BMC Bioinformatics 6:201. 2005..e., genes and gene products annotated with GO terms). Tools that allow users to directly search and inspect relations among all GO terms and their associated genes and gene products from multiple databases are needed...
PIRSF: family classification system at the Protein Information ResourceCathy H Wu
Department of Biochemistry and Molecular Biology, Georgetown University Medical Center, 3900 Reservoir Road, NW, Box 571414, Washington, DC 20057 1414, USA
Nucleic Acids Res 32:D112-4. 2004..PIRSF can be utilized to analyze phylogenetic profiles, to reveal functional convergence and divergence, and to identify interesting relationships between homeomorphic families, domains and structural classes...
The Protein Information Resource: an integrated public resource of functional annotation of proteinsCathy H Wu
National Biomedical Research Foundation, Georgetown University Medical Center, 3900 Reservoir Road, NW, Washington, DC 20007, USA
Nucleic Acids Res 30:35-7. 2002..The PIR databases and other files are also available by FTP (ftp://nbrfa.georgetown.edu/pir_databases)...
A comparison study on algorithms of detecting long forms for short forms in biomedical textManabu Torii
Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University Medical Center, 4000 Resevoir Rd, NW, Washington, DC 20057, USA
BMC Bioinformatics 8:S5. 2007....
dbOGAP - an integrated bioinformatics resource for protein O-GlcNAcylationJinlian Wang
Department of Oncology, Georgetown University Medical Center, NW, Washington, DC 20007, USA
BMC Bioinformatics 12:91. 2011..Furthermore, a bioinformatics resource for O-GlcNAcylation is lacking, and an O-GlcNAcylation site prediction tool is much needed...
Quantitative assessment of dictionary-based protein named entity taggingHongfang Liu
Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University Medical Center, Washington, DC 20007, USA
J Am Med Inform Assoc 13:497-507. 2006....
Integration of bioinformatics resources for functional analysis of gene expression and proteomic dataHongzhan Huang
Protein Information Resource PIR, Department of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, Washington, DC 20007, USA
Front Biosci 12:5071-88. 2007....
Proteomic analysis of pathways involved in estrogen-induced growth and apoptosis of breast cancer cellsZhang Zhi Hu
Lombardi Cancer Center, Georgetown University, Washington, DC, United States of America
PLoS ONE 6:e20410. 2011..Paradoxically, in breast cancer cells that have been chronically deprived of estrogen stimulation, re-introduction of the hormone can induce apoptosis...
Computational analysis and identification of amino acid sites in dengue E proteins relevant to development of diagnostics and vaccinesRaja Mazumder
Department of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, Washington, DC 20007, USA
Virus Genes 35:175-86. 2007....
