Zhang Zhi Hu

Summary

Affiliation: Georgetown University
Country: USA

Publications

  1. ncbi request reprint Literature mining and database annotation of protein phosphorylation using a rule-based system
    Z Z Hu
    Department of Biochemistry and Molecular Biology, Georgetown University Medical Center, Washington, DC 20057, USA
    Bioinformatics 21:2759-65. 2005
  2. pmc Omics-based molecular target and biomarker identification
    Zhang Zhi Hu
    Lombardi Cancer Center, Georgetown University, Washington, DC, USA
    Methods Mol Biol 719:547-71. 2011
  3. pmc Framework for a protein ontology
    Darren A Natale
    Department of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, 3300 Whitehaven St, NW, Washington, DC 20007, USA
    BMC Bioinformatics 8:S1. 2007
  4. pmc DynGO: a tool for visualizing and mining of Gene Ontology and its associations
    Hongfang Liu
    Department of Information Systems, University of Maryland, Baltimore County, 1000 Hilltop Circle, MD 21050, USA
    BMC Bioinformatics 6:201. 2005
  5. pmc PIRSF: family classification system at the Protein Information Resource
    Cathy H Wu
    Department of Biochemistry and Molecular Biology, Georgetown University Medical Center, 3900 Reservoir Road, NW, Box 571414, Washington, DC 20057 1414, USA
    Nucleic Acids Res 32:D112-4. 2004
  6. pmc The Protein Information Resource: an integrated public resource of functional annotation of proteins
    Cathy H Wu
    National Biomedical Research Foundation, Georgetown University Medical Center, 3900 Reservoir Road, NW, Washington, DC 20007, USA
    Nucleic Acids Res 30:35-7. 2002
  7. pmc A comparison study on algorithms of detecting long forms for short forms in biomedical text
    Manabu Torii
    Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University Medical Center, 4000 Resevoir Rd, NW, Washington, DC 20057, USA
    BMC Bioinformatics 8:S5. 2007
  8. pmc dbOGAP - an integrated bioinformatics resource for protein O-GlcNAcylation
    Jinlian Wang
    Department of Oncology, Georgetown University Medical Center, NW, Washington, DC 20007, USA
    BMC Bioinformatics 12:91. 2011
  9. pmc Quantitative assessment of dictionary-based protein named entity tagging
    Hongfang Liu
    Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University Medical Center, Washington, DC 20007, USA
    J Am Med Inform Assoc 13:497-507. 2006
  10. ncbi request reprint Integration of bioinformatics resources for functional analysis of gene expression and proteomic data
    Hongzhan Huang
    Protein Information Resource PIR, Department of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, Washington, DC 20007, USA
    Front Biosci 12:5071-88. 2007

Detail Information

Publications12

  1. ncbi request reprint Literature mining and database annotation of protein phosphorylation using a rule-based system
    Z Z Hu
    Department of Biochemistry and Molecular Biology, Georgetown University Medical Center, Washington, DC 20057, USA
    Bioinformatics 21:2759-65. 2005
    ..While of great value, such information is limited in databases owing to the laborious process of literature-based curation. Computational literature mining holds promise to facilitate database curation...
  2. pmc Omics-based molecular target and biomarker identification
    Zhang Zhi Hu
    Lombardi Cancer Center, Georgetown University, Washington, DC, USA
    Methods Mol Biol 719:547-71. 2011
    ..We describe a downstream workflow and procedures for functional analysis that focus on biological pathways, from which molecular targets can be derived and proposed for experimental validation...
  3. pmc Framework for a protein ontology
    Darren A Natale
    Department of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, 3300 Whitehaven St, NW, Washington, DC 20007, USA
    BMC Bioinformatics 8:S1. 2007
    ..Here we describe the initial development of PRO, illustrated using human and mouse proteins involved in the transforming growth factor-beta and bone morphogenetic protein signaling pathways...
  4. pmc DynGO: a tool for visualizing and mining of Gene Ontology and its associations
    Hongfang Liu
    Department of Information Systems, University of Maryland, Baltimore County, 1000 Hilltop Circle, MD 21050, USA
    BMC Bioinformatics 6:201. 2005
    ..e., genes and gene products annotated with GO terms). Tools that allow users to directly search and inspect relations among all GO terms and their associated genes and gene products from multiple databases are needed...
  5. pmc PIRSF: family classification system at the Protein Information Resource
    Cathy H Wu
    Department of Biochemistry and Molecular Biology, Georgetown University Medical Center, 3900 Reservoir Road, NW, Box 571414, Washington, DC 20057 1414, USA
    Nucleic Acids Res 32:D112-4. 2004
    ..PIRSF can be utilized to analyze phylogenetic profiles, to reveal functional convergence and divergence, and to identify interesting relationships between homeomorphic families, domains and structural classes...
  6. pmc The Protein Information Resource: an integrated public resource of functional annotation of proteins
    Cathy H Wu
    National Biomedical Research Foundation, Georgetown University Medical Center, 3900 Reservoir Road, NW, Washington, DC 20007, USA
    Nucleic Acids Res 30:35-7. 2002
    ..The PIR databases and other files are also available by FTP (ftp://nbrfa.georgetown.edu/pir_databases)...
  7. pmc A comparison study on algorithms of detecting long forms for short forms in biomedical text
    Manabu Torii
    Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University Medical Center, 4000 Resevoir Rd, NW, Washington, DC 20057, USA
    BMC Bioinformatics 8:S5. 2007
    ....
  8. pmc dbOGAP - an integrated bioinformatics resource for protein O-GlcNAcylation
    Jinlian Wang
    Department of Oncology, Georgetown University Medical Center, NW, Washington, DC 20007, USA
    BMC Bioinformatics 12:91. 2011
    ..Furthermore, a bioinformatics resource for O-GlcNAcylation is lacking, and an O-GlcNAcylation site prediction tool is much needed...
  9. pmc Quantitative assessment of dictionary-based protein named entity tagging
    Hongfang Liu
    Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University Medical Center, Washington, DC 20007, USA
    J Am Med Inform Assoc 13:497-507. 2006
    ....
  10. ncbi request reprint Integration of bioinformatics resources for functional analysis of gene expression and proteomic data
    Hongzhan Huang
    Protein Information Resource PIR, Department of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, Washington, DC 20007, USA
    Front Biosci 12:5071-88. 2007
    ....
  11. pmc Proteomic analysis of pathways involved in estrogen-induced growth and apoptosis of breast cancer cells
    Zhang Zhi Hu
    Lombardi Cancer Center, Georgetown University, Washington, DC, United States of America
    PLoS ONE 6:e20410. 2011
    ..Paradoxically, in breast cancer cells that have been chronically deprived of estrogen stimulation, re-introduction of the hormone can induce apoptosis...
  12. ncbi request reprint Computational analysis and identification of amino acid sites in dengue E proteins relevant to development of diagnostics and vaccines
    Raja Mazumder
    Department of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, Washington, DC 20007, USA
    Virus Genes 35:175-86. 2007
    ....