Sonia de Assis
Affiliation: Georgetown University
- High-fat or ethinyl-oestradiol intake during pregnancy increases mammary cancer risk in several generations of offspringSonia de Assis
Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, 3970 Reservoir Road NW, The Research Building, Room E407, Washington, District of Columbia 20057, USA
Nat Commun 3:1053. 2012..We conclude that dietary and oestrogenic exposures in pregnancy increase breast cancer risk in multiple generations of offspring, possibly through epigenetic means...
- Dietary fat intake and gestational weight gain in relation to estradiol and progesterone plasma levels during pregnancy: a longitudinal study in Swedish womenMarie Lof
Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Box 281, SE 171 77 Stockholm, Sweden
BMC Womens Health 9:10. 2009....
- Exposures to synthetic estrogens at different times during the life, and their effect on breast cancer riskLeena Hilakivi-Clarke
Department of Oncology, Georgetown University, Washington, DC 20057, USA
J Mammary Gland Biol Neoplasia 18:25-42. 2013..New data suggest that these exposures induce epigenetic modifications in the mammary gland and germ cells, thereby causing an inheritable increase in breast cancer risk for multiple generations...
- Timing of dietary estrogenic exposures and breast cancer riskSonia de Assis
Department of Oncology, Georgetown University, Research Building E407, 3970 Reservoir Road NW, Washington, DC 20057, USA
Ann N Y Acad Sci 1089:14-35. 2006..Thus, dietary exposures during pregnancy and puberty may play an important role in determining later risk by inducing epigenetic changes that modify vulnerability to breast cancer...
- Protective effects of prepubertal genistein exposure on mammary tumorigenesis are dependent on BRCA1 expressionSonia de Assis
Lombardi Comprehensive Cancer Center and Department of Oncology, Georgetown University, Washington, District of Columbia, USA
Cancer Prev Res (Phila) 4:1436-48. 2011....
- Genetic and epigenetic alterations in sentinel lymph nodes metastatic lesions compared to their corresponding primary breast tumorsLuciane R Cavalli
Lombardi Cancer Center, Georgetown University Medical Center, 3800 Reservoir Road, Washington, DC 20007, USA
Cancer Genet Cytogenet 146:33-40. 2003..Characterization of such alterations may lead to identification of initial events associated with the metastatic dissemination process...
- Fetal origins of breast cancerLeena Hilakivi-Clarke
Georgetown University, Washington DC 20057, USA
Trends Endocrinol Metab 17:340-8. 2006..Identifying the epigenetically altered target genes and their ligands might lead to strategies to prevent this disease in some women...