Amrita K Cheema

Summary

Affiliation: Georgetown University
Country: USA

Publications

  1. doi request reprint Functional proteomics analysis to study ATM dependent signaling in response to ionizing radiation
    Amrita K Cheema
    Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA
    Radiat Res 179:674-83. 2013
  2. pmc Using a spike-in experiment to evaluate analysis of LC-MS data
    Leepika Tuli
    Lombardi Comprehensive Cancer Center, Georgetown University, 4000 Reservoir Rd, Washington, DC, USA
    Proteome Sci 10:13. 2012
  3. doi request reprint Integrated analysis of ATM mediated gene and protein expression impacting cellular metabolism
    Amrita K Cheema
    Department of Oncology, Lombardi Comprehensive Cancer Center at Georgetown University Medical Center, Washington, DC 20057, United States
    J Proteome Res 10:2651-7. 2011
  4. pmc LC-MS based serum metabolomics for identification of hepatocellular carcinoma biomarkers in Egyptian cohort
    Jun Feng Xiao
    Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, United States
    J Proteome Res 11:5914-23. 2012
  5. pmc Human fibroblasts for large-scale "omics" investigations of ATM gene function
    Mira Jung
    Department of Radiation Medicine, Georgetown University Medical Center, Washington, DC 20057, USA
    Adv Exp Med Biol 720:181-90. 2011
  6. doi request reprint Quantitative metabolomic and lipidomic profiling reveals aberrant amino acid metabolism in type 2 diabetes
    Prabhjit Kaur
    Department of Oncology, Lombardi Comprehensive Cancer Center at Georgetown University Medical Center, Washington, DC, USA
    Mol Biosyst 9:307-17. 2013
  7. pmc Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex
    Tushar B Deb
    Dept of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3970 Reservoir Road NW, Washington, DC 20057, USA
    Am J Physiol Cell Physiol 300:C1139-54. 2011
  8. pmc A new method for alignment of LC-MALDI-TOF data
    Zhiqun Tang
    Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA
    Proteome Sci 9:S10. 2011
  9. doi request reprint iTRAQ-based quantitative protein expression profiling and MRM verification of markers in type 2 diabetes
    Prabhjit Kaur
    Department of Oncology, Lombardi Comprehensive Cancer Center at Georgetown University Medical Center, Washington, D C, USA
    J Proteome Res 11:5527-39. 2012
  10. pmc Utilization of metabolomics to identify serum biomarkers for hepatocellular carcinoma in patients with liver cirrhosis
    Habtom W Ressom
    Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA
    Anal Chim Acta 743:90-100. 2012

Collaborators

Detail Information

Publications11

  1. doi request reprint Functional proteomics analysis to study ATM dependent signaling in response to ionizing radiation
    Amrita K Cheema
    Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA
    Radiat Res 179:674-83. 2013
    ..These molecular networks offer a hypothesis generating function for further investigations of cellular stress responses...
  2. pmc Using a spike-in experiment to evaluate analysis of LC-MS data
    Leepika Tuli
    Lombardi Comprehensive Cancer Center, Georgetown University, 4000 Reservoir Rd, Washington, DC, USA
    Proteome Sci 10:13. 2012
    ..abstract:..
  3. doi request reprint Integrated analysis of ATM mediated gene and protein expression impacting cellular metabolism
    Amrita K Cheema
    Department of Oncology, Lombardi Comprehensive Cancer Center at Georgetown University Medical Center, Washington, DC 20057, United States
    J Proteome Res 10:2651-7. 2011
    ..Furthermore, our results support the feasibility of applying a systems approach for identification of specific cellular networks and understanding of pathway perturbations underlying the complex A-T clinical syndrome...
  4. pmc LC-MS based serum metabolomics for identification of hepatocellular carcinoma biomarkers in Egyptian cohort
    Jun Feng Xiao
    Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, United States
    J Proteome Res 11:5914-23. 2012
    ..This is the first MS-based metabolic biomarker discovery study on Egyptian subjects that led to the identification of candidate metabolites that discriminate early stage HCC from patients with liver cirrhosis...
  5. pmc Human fibroblasts for large-scale "omics" investigations of ATM gene function
    Mira Jung
    Department of Radiation Medicine, Georgetown University Medical Center, Washington, DC 20057, USA
    Adv Exp Med Biol 720:181-90. 2011
    ..We present here a summary of the derivation and characterization of cells comprising this model cell system and review applications of this model to systems analysis of ATM functions...
  6. doi request reprint Quantitative metabolomic and lipidomic profiling reveals aberrant amino acid metabolism in type 2 diabetes
    Prabhjit Kaur
    Department of Oncology, Lombardi Comprehensive Cancer Center at Georgetown University Medical Center, Washington, DC, USA
    Mol Biosyst 9:307-17. 2013
    ..A systems approach offers promise towards identification of clinically relevant markers of T2DM and novel molecular targets to foster drug discovery for effective therapeutic development for diabetes...
  7. pmc Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex
    Tushar B Deb
    Dept of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3970 Reservoir Road NW, Washington, DC 20057, USA
    Am J Physiol Cell Physiol 300:C1139-54. 2011
    ....
  8. pmc A new method for alignment of LC-MALDI-TOF data
    Zhiqun Tang
    Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA
    Proteome Sci 9:S10. 2011
    ..Thus, label-free differential protein expression studies by LC-MS technology require alignment with respect to both RT and m/z to ensure that same proteins/peptides are compared from multiple runs...
  9. doi request reprint iTRAQ-based quantitative protein expression profiling and MRM verification of markers in type 2 diabetes
    Prabhjit Kaur
    Department of Oncology, Lombardi Comprehensive Cancer Center at Georgetown University Medical Center, Washington, D C, USA
    J Proteome Res 11:5527-39. 2012
    ..These putative biomarkers may be clinically useful for subset stratification of T2DM patients as well as for the development of novel therapeutics targeting the specific pathology...
  10. pmc Utilization of metabolomics to identify serum biomarkers for hepatocellular carcinoma in patients with liver cirrhosis
    Habtom W Ressom
    Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA
    Anal Chim Acta 743:90-100. 2012
    ..Our work shows that metabolomic profiling is a promising tool to identify candidate metabolic biomarkers for early detection of HCC cases in high risk population of cirrhotic patients...
  11. pmc STAT3 suppresses transcription of proapoptotic genes in cancer cells with the involvement of its N-terminal domain
    Olga A Timofeeva
    Department of Oncology and Radiation Medicine, and Drug Discovery Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA
    Proc Natl Acad Sci U S A 110:1267-72. 2013
    ..These data demonstrate a suppressive role for the STAT3 ND in the regulation of proapoptotic gene expression in cancer cells, providing further support for targeting STAT3 ND for cancer therapy...