Research TopicsSpecies | Amrita K CheemaSummaryAffiliation: Georgetown University Country: USA Publications
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Detail Information
Publications
Quantitative metabolomic and lipidomic profiling reveals aberrant amino acid metabolism in type 2 diabetesPrabhjit Kaur
Department of Oncology, Lombardi Comprehensive Cancer Center at Georgetown University Medical Center, Washington, DC, USA
Mol Biosyst 9:307-17. 2013..A systems approach offers promise towards identification of clinically relevant markers of T2DM and novel molecular targets to foster drug discovery for effective therapeutic development for diabetes...
Using a spike-in experiment to evaluate analysis of LC-MS dataLeepika Tuli
Lombardi Comprehensive Cancer Center, Georgetown University, 4000 Reservoir Rd, Washington, DC, USA
Proteome Sci 10:13. 2012..abstract:..
A new method for alignment of LC-MALDI-TOF dataZhiqun Tang
Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA
Proteome Sci 9:S10. 2011..Thus, label-free differential protein expression studies by LC-MS technology require alignment with respect to both RT and m/z to ensure that same proteins/peptides are compared from multiple runs...
Integrated analysis of ATM mediated gene and protein expression impacting cellular metabolismAmrita K Cheema
Department of Oncology, Lombardi Comprehensive Cancer Center at Georgetown University Medical Center, Washington, DC 20057, United States
J Proteome Res 10:2651-7. 2011..Furthermore, our results support the feasibility of applying a systems approach for identification of specific cellular networks and understanding of pathway perturbations underlying the complex A-T clinical syndrome...
Human fibroblasts for large-scale "omics" investigations of ATM gene functionMira Jung
Department of Radiation Medicine, Georgetown University Medical Center, Washington, DC 20057, USA
Adv Exp Med Biol 720:181-90. 2011..We present here a summary of the derivation and characterization of cells comprising this model cell system and review applications of this model to systems analysis of ATM functions...
iTRAQ-based quantitative protein expression profiling and MRM verification of markers in type 2 diabetesPrabhjit Kaur
Department of Oncology, Lombardi Comprehensive Cancer Center at Georgetown University Medical Center, Washington, D C, USA
J Proteome Res 11:5527-39. 2012..These putative biomarkers may be clinically useful for subset stratification of T2DM patients as well as for the development of novel therapeutics targeting the specific pathology...
Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complexTushar B Deb
Dept of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3970 Reservoir Road NW, Washington, DC 20057, USA
Am J Physiol Cell Physiol 300:C1139-54. 2011....
