Research Topics
Genomes and Genes | Luciane R CavalliSummaryAffiliation: Georgetown University Country: USA Publications
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Publications
Amplification of the BP1 homeobox gene in breast cancerLuciane R Cavalli
Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, 3800 Reservoir Rd, Room S165A LL Lombardi Building, Washington, DC 20007, USA
Cancer Genet Cytogenet 187:19-24. 2008..Considering that BP1 expression was observed in cases with both increased and normal BP1 copy number, we conclude that other mechanisms in addition to gene amplification play a role in BP1 protein expression...- Molecular markers of breast axillary lymph node metastasisLuciane R Cavalli
Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3800 Reservoir Rd, NW, LCCC LL Room S165A, Washington, DC 20007, USA
Expert Rev Mol Diagn 9:441-54. 2009.... 
Loss of heterozygosity in normal breast epithelial tissue and benign breast lesions in BRCA1/2 carriers with breast cancerLuciane R Cavalli
Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA
Cancer Genet Cytogenet 149:38-43. 2004..Our results suggest that there is a field effect of early genetic events preceding morphologic changes in the mammary glands of BRCA mutation carriers...- Lack of DNA copy number alterations revealed with comparative genomic hybridization in fibroadenomas of the breastLuciane R Cavalli
Institute for Molecular and Human Genetics, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3800 Reservoir Road NW, Main 4000, Washington, DC 20007, USA
Cancer Genet Cytogenet 153:173-6. 2004..We discuss our results and compare them to other reports on fibroadenomas... - Genetic and epigenetic alterations in sentinel lymph nodes metastatic lesions compared to their corresponding primary breast tumorsLuciane R Cavalli
Lombardi Cancer Center, Georgetown University Medical Center, 3800 Reservoir Road, Washington, DC 20007, USA
Cancer Genet Cytogenet 146:33-40. 2003..Characterization of such alterations may lead to identification of initial events associated with the metastatic dissemination process... 
Frequent loss of heterozygosity at the interferon regulatory factor-1 gene locus in breast cancerLuciane R Cavalli
Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University School of Medicine, Washington, DC 20057, USA
Breast Cancer Res Treat 121:227-31. 2010..00; P = 0.003; n = 273 cases) and risk of death (OR = 4.18; P = 0.004; n = 191 cases). Our findings strongly imply a tumor suppressor role for the IRF1 gene in breast cancer...- Deletion, methylation, and expression of the NKX3.1 suppressor gene in primary human prostate cancerEkatherine Asatiani
Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA
Cancer Res 65:1164-73. 2005..Samples with protein expression below the median level in cancer cells had both NKX3.1 deletion and selective CpG methylation... - Molecular cloning, genomic organization, chromosomal mapping and subcellular localization of mouse PAP7: a PBR and PKA-RIalpha associated proteinJun Liu
Division of Hormone Research, Department of Cell Biology, Georgetown University Medical Center, 3900 Reservoir Road, NW, Washington, DC 20057, USA
Gene 308:1-10. 2003..e. mitochondria, where phosphorylation of specific protein substrates mediates the hormone-induced steroid formation... - Peripheral-type benzodiazepine receptor (PBR) gene amplification in MDA-MB-231 aggressive breast cancer cellsMatthew Hardwick
Division of Hormone Research, Department of Cell Biology, Georgetown University Medical Center, Georgetown, Washington DC 20007, USA
Cancer Genet Cytogenet 139:48-51. 2002..These data suggest that PBR gene amplification may be an important indicator of breast cancer progression... - ERRgamma mediates tamoxifen resistance in novel models of invasive lobular breast cancerRebecca B Riggins
Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University School of Medicine, Washington, District of Columbia 20057, USA
Cancer Res 68:8908-17. 2008..These data support a role for ERRgamma/AP1 signaling in the development of TAM resistance and suggest that expression of ERRgamma may be a marker of poor TAM response... - Detection of LOH and mitochondrial DNA alterations in ductal lavage and nipple aspirate fluids from hngh-risk patientsClaudine Isaacs
Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA
Breast Cancer Res Treat 84:99-105. 2004..One NAF sample from a BRCA1 patient showed a mtDNA mutation. Our data demonstrates the feasibility of performing molecular studies using the free DNA present in the ductal fluid, while the intact cells can be used for cytologic studies... - Evaluation of adult papillary thyroid carcinomas by comparative genomic hybridization and microsatellite instability analysisAndrew J Bauer
Department of Pediatrics, Walter Reed Army Medical Center, USA, Washington, DC, USA
Cancer Genet Cytogenet 135:182-6. 2002..026). We conclude that although chromosomal and microsatellite instability are uncommon in PTC, tumors with chromosomal aberrations are more likely to be associated with invasion... - Radiation-generated short DNA fragments may perturb non-homologous end-joining and induce genomic instabilityDalong Pang
Department of Radiation Medicine, Georgetown University Medical Center, USA
J Radiat Res 52:309-19. 2011.... - Haploinsufficiency of cytochrome P450 17alpha-hydroxylase/17,20 lyase (CYP17) causes infertility in male miceYing Liu
Department of Biochemistry and Molecular Biology, Georgetown University Medical Center, Washington, DC 20057, USA
Mol Endocrinol 19:2380-9. 2005....