Genomes and Genes

Species

Gerard Ahern

Summary

Affiliation: Georgetown University
Country: USA

Publications

  1. Ahern G. 5-HT and the immune system. Curr Opin Pharmacol. 2011;11:29-33 pubmed publisher
    ..Furthermore, a recent paper describing the immune phenotype of 5-HT deficient mice is discussed. ..
  2. Phan T, Ton H, Chen Y, Basha M, Ahern G. Sex-dependent expression of TRPV1 in bladder arterioles. Am J Physiol Renal Physiol. 2016;311:F1063-F1073 pubmed publisher
    ..TRPV1 may therefore play an important role in regulating the microcirculation of the female bladder, and this effect may be of significance during inflammatory conditions. ..
  3. Ton H, Phan T, Abramyan A, Shi L, Ahern G. Identification of a putative binding site critical for general anesthetic activation of TRPA1. Proc Natl Acad Sci U S A. 2017;114:3762-3767 pubmed publisher
    ..These data may provide a structural basis for designing drugs to counter the noxious and vasorelaxant properties of general anesthetics and may prove useful in understanding effects of anesthetics on related ion channels. ..
  4. request reprint
    Ahern G. Activation of TRPV1 by the satiety factor oleoylethanolamide. J Biol Chem. 2003;278:30429-34 pubmed
    ..Thus, TRPV1 represents a potential target for OEA and may contribute to the excitatory action of OEA on sensory nerves. ..

Detail Information

Publications4

  1. Ahern G. 5-HT and the immune system. Curr Opin Pharmacol. 2011;11:29-33 pubmed publisher
    ..Furthermore, a recent paper describing the immune phenotype of 5-HT deficient mice is discussed. ..
  2. Phan T, Ton H, Chen Y, Basha M, Ahern G. Sex-dependent expression of TRPV1 in bladder arterioles. Am J Physiol Renal Physiol. 2016;311:F1063-F1073 pubmed publisher
    ..TRPV1 may therefore play an important role in regulating the microcirculation of the female bladder, and this effect may be of significance during inflammatory conditions. ..
  3. Ton H, Phan T, Abramyan A, Shi L, Ahern G. Identification of a putative binding site critical for general anesthetic activation of TRPA1. Proc Natl Acad Sci U S A. 2017;114:3762-3767 pubmed publisher
    ..These data may provide a structural basis for designing drugs to counter the noxious and vasorelaxant properties of general anesthetics and may prove useful in understanding effects of anesthetics on related ion channels. ..
  4. request reprint
    Ahern G. Activation of TRPV1 by the satiety factor oleoylethanolamide. J Biol Chem. 2003;278:30429-34 pubmed
    ..Thus, TRPV1 represents a potential target for OEA and may contribute to the excitatory action of OEA on sensory nerves. ..