Serguei Popov

Summary

Affiliation: George Mason University
Country: USA

Publications

  1. ncbi Platelets, inflammatory cells, von Willebrand factor, syndecan-1, fibrin, fibronectin, and bacteria co-localize in the liver thrombi of Bacillus anthracis-infected mice
    Taissia G Popova
    National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, VA 20110, USA
    Microb Pathog 52:1-9. 2012
  2. ncbi Acceleration of epithelial cell syndecan-1 shedding by anthrax hemolytic virulence factors
    Taissia G Popova
    National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, VA 20110, USA
    BMC Microbiol 6:8. 2006
  3. ncbi Effective antiprotease-antibiotic treatment of experimental anthrax
    Serguei G Popov
    Advanced Biosystems, Inc, Manassas, VA, USA
    BMC Infect Dis 5:25. 2005
  4. ncbi Transcriptional and apoptotic responses of THP-1 cells to challenge with toxigenic, and non-toxigenic Bacillus anthracis
    Christopher Bradburne
    Center for Bio Molecular Science and Engineering Code 6900, US Naval Research Laboratory, Washington DC, USA
    BMC Immunol 9:67. 2008
  5. ncbi Bacillus anthracis protease InhA regulates BslA-mediated adhesion in human endothelial cells
    Jessica H Tonry
    Department of Biosciences and Biomedical Research Laboratory, George Mason University, 10650 Pyramid Place, Manassas, Virginia 20110, USA
    Cell Microbiol 14:1219-30. 2012
  6. ncbi Secreted Bacillus anthracis proteases target the host fibrinolytic system
    Myung Chul Chung
    National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, VA, USA
    FEMS Immunol Med Microbiol 62:173-81. 2011
  7. ncbi Bacillus anthracis protease InhA increases blood-brain barrier permeability and contributes to cerebral hemorrhages
    Dhritiman V Mukherjee
    National Center for Biodefense and Infectious Diseases, Department of Molecular and Microbiology, George Mason University, Manassas, Virginia, United States of America
    PLoS ONE 6:e17921. 2011
  8. ncbi Anthrax infection inhibits the AKT signaling involved in the E-cadherin-mediated adhesion of lung epithelial cells
    Taissia Popova
    National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, VA 20110, USA
    FEMS Immunol Med Microbiol 56:129-42. 2009

Collaborators

Detail Information

Publications8

  1. ncbi Platelets, inflammatory cells, von Willebrand factor, syndecan-1, fibrin, fibronectin, and bacteria co-localize in the liver thrombi of Bacillus anthracis-infected mice
    Taissia G Popova
    National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, VA 20110, USA
    Microb Pathog 52:1-9. 2012
    ....
  2. ncbi Acceleration of epithelial cell syndecan-1 shedding by anthrax hemolytic virulence factors
    Taissia G Popova
    National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, VA 20110, USA
    BMC Microbiol 6:8. 2006
    ..We tested if acceleration of Synd1 shedding takes place in vitro upon treatment of epithelial cells with B. anthracis hemolysins, as well as in vivo during anthrax infection in mice...
  3. ncbi Effective antiprotease-antibiotic treatment of experimental anthrax
    Serguei G Popov
    Advanced Biosystems, Inc, Manassas, VA, USA
    BMC Infect Dis 5:25. 2005
    ..anthracis distinct from lethal toxin...
  4. ncbi Transcriptional and apoptotic responses of THP-1 cells to challenge with toxigenic, and non-toxigenic Bacillus anthracis
    Christopher Bradburne
    Center for Bio Molecular Science and Engineering Code 6900, US Naval Research Laboratory, Washington DC, USA
    BMC Immunol 9:67. 2008
    ..In fact, responses brought about by the toxins may be different than each of their individual effects...
  5. ncbi Bacillus anthracis protease InhA regulates BslA-mediated adhesion in human endothelial cells
    Jessica H Tonry
    Department of Biosciences and Biomedical Research Laboratory, George Mason University, 10650 Pyramid Place, Manassas, Virginia 20110, USA
    Cell Microbiol 14:1219-30. 2012
    ..BslA was sensitive to purified InhA degradation in a concentration- and time-dependent manner. Taken together these data support the role of InhA regulation of BslA-mediated vegetative cell adhesion and invasion...
  6. ncbi Secreted Bacillus anthracis proteases target the host fibrinolytic system
    Myung Chul Chung
    National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, VA, USA
    FEMS Immunol Med Microbiol 62:173-81. 2011
    ..We propose that NprB and InhA may contribute to the activation of the fibrinolytic system in anthrax infection...
  7. ncbi Bacillus anthracis protease InhA increases blood-brain barrier permeability and contributes to cerebral hemorrhages
    Dhritiman V Mukherjee
    National Center for Biodefense and Infectious Diseases, Department of Molecular and Microbiology, George Mason University, Manassas, Virginia, United States of America
    PLoS ONE 6:e17921. 2011
    ..Cumulatively, these findings indicate that InhA contributes to BBB disruption associated with anthrax meningitis through proteolytic attack on the endothelial tight junctional protein zonula occluden (ZO)-1...
  8. ncbi Anthrax infection inhibits the AKT signaling involved in the E-cadherin-mediated adhesion of lung epithelial cells
    Taissia Popova
    National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, VA 20110, USA
    FEMS Immunol Med Microbiol 56:129-42. 2009
    ..We conclude that the PI3K/AKT pathway controlling the integrity of epithelium plays an important survival role in anthrax infection...