Research Topics
| Judith HsiaSummaryAffiliation: George Washington University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Metabolic syndrome and coronary angiographic disease progression: the Women's Angiographic Vitamin & Estrogen trialJudith Hsia
Department of Medicine, George Washington University, Washington, DC, USA
Am Heart J 146:439-45. 2003....
Physical activity and diabetes risk in postmenopausal womenJudith Hsia
Department of Medicine, George Washington University, Washington, DC, USA
Am J Prev Med 28:19-25. 2005..To evaluate the hypothesis that physical activity independently predicts type 2 diabetes risk in postmenopausal African-American, Hispanic, Asian, and Caucasian women...
Conjugated equine estrogens and coronary heart disease: the Women's Health InitiativeJudith Hsia
Department of Medicine, George Washington University, Washington, DC, USA
Arch Intern Med 166:357-65. 2006..These trials did not address the role of unopposed estrogen for coronary protection...
Assessing drug risks and benefits: lessons from postmenopausal hormone therapy studiesJudith Hsia
Division of Cardiology, George Washington University, Washington, DC 20037, USA
Clin Breast Cancer 6:S65-70. 2006....
Predictors of angina pectoris versus myocardial infarction from the Women's Health Initiative Observational StudyJudith Hsia
George Washington University, Washington, DC 20037, USA
Am J Cardiol 93:673-8. 2004..Thus, specific risk factors strongly and independently predicted whether women with an acute coronary syndrome would present with angina or with MI...
Conjugated equine estrogens and peripheral arterial disease risk: the Women's Health InitiativeJudith Hsia
Department of Medicine, George Washington University, Washington, DC, USA
Am Heart J 152:170-6. 2006..Estradiol reduced progression of ultrasonographic carotid disease in a randomized trial. No trials of unopposed estrogen for prevention of lower extremity arterial disease or aortic aneurysm have been conducted...
Estrogen plus progestin and the risk of peripheral arterial disease: the Women's Health InitiativeJudith Hsia
Department of Medicine, George Washington University, Washington, DC, USA
Circulation 109:620-6. 2004..This analysis evaluates clinical peripheral arterial disease among generally healthy women in the Women's Health Initiative randomized trial of estrogen plus progestin...
Calcium/vitamin D supplementation and cardiovascular eventsJudith Hsia
Department of Medicine, George Washington University, Washington, DC, USA
Circulation 115:846-54. 2007..We evaluated the risk of coronary and cerebrovascular events in the Women's Health Initiative randomized trial of calcium plus vitamin D supplementation...
Progression of coronary calcification in healthy postmenopausal womenJudith Hsia
Department of Medicine, The George Washington University, Washington, DC 20037, USA
BMC Cardiovasc Disord 4:21. 2004..This study prospectively evaluated rates and determinants of progression of coronary artery calcium score in a group of healthy postmenopausal women...
Prehypertension and cardiovascular disease risk in the Women's Health InitiativeJudith Hsia
Department of Medicine, George Washington University, 2150 Pennsylvania Ave NW, Washington, DC 20037, USA
Circulation 115:855-60. 2007..Prehypertension is common and is associated with increased vascular mortality. The extent to which it increases risk of nonfatal myocardial infarction, stroke, and congestive heart failure is less clear...
Usefulness of prior hysterectomy as an independent predictor of Framingham risk score (The Women's Health Initiative)Judith Hsia
George Washington University, Washington, DC 20037, USA
Am J Cardiol 92:264-9. 2003..04). In multivariate analysis, hysterectomy with bilateral oophorectomy was an independent predictor of Framingham risk (p = 0.04), whereas hysterectomy with ovarian preservation was not...
PRO: Should aspirin be used in all women older than 65 years to prevent stroke?Judith Hsia
Lipid Research Clinic, Washington, DC 20037, USA
Prev Cardiol 10:6-11. 2007..Results of the Women's Health Study showed that although there is a risk of bleeding events with aspirin use, overall this risk is outweighed by the number of strokes prevented...
Compliance with National Cholesterol Education Program dietary and lifestyle guidelines among older women with self-reported hypercholesterolemia. The Women's Health InitiativeJudith Hsia
Department of Medicine, George Washington University, Washington, DC, USA
Am J Med 113:384-92. 2002..Dietary therapy remains the first line of treatment for patients with high blood cholesterol levels. Among free-living persons, compliance with National Cholesterol Education Program (NCEP) dietary recommendations is uncertain...
Women's angiographic vitamin and estrogen trial: design and methodsJudith Hsia
Department of Medicine, George Washington University, Washington, DC, USA
Control Clin Trials 23:708-27. 2002..Quantitative coronary angiography was performed at baseline and repeated after projected mean follow-up of 3 years...
Effects of hormone replacement therapy and antioxidant vitamin supplements on coronary atherosclerosis in postmenopausal women: a randomized controlled trialDavid D Waters
Division of Cardiology, Room 5G1, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA
JAMA 288:2432-40. 2002..Hormone replacement therapy (HRT) and antioxidant vitamins are widely used for secondary prevention in postmenopausal women with coronary disease, but no clinical trials have demonstrated benefit to support their use...
Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification TrialBarbara V Howard
MedStar Research Institute Howard University, Washington, DC, USA
JAMA 295:655-66. 2006..Multiple epidemiologic studies and some trials have linked diet with cardiovascular disease (CVD) prevention, but long-term intervention data are needed...
Postmenopausal hormone therapy is associated with atherosclerosis progression in women with abnormal glucose toleranceBarbara V Howard
MedStar Research Institute, 6495 New Hampshire Ave, Suite 201, Hyattsville, MD 20783, USA
Circulation 110:201-6. 2004..In this study, we hypothesized that PHT would have a worse effect on disease among women with AGT...
Evaluation of the American Heart Association cardiovascular disease prevention guideline for womenJudith Hsia
George Washington University, Washington, DC, USA
Circ Cardiovasc Qual Outcomes 3:128-34. 2010..We assigned Women's Health Initiative participants to risk categories as described in the guideline and evaluated clinical event rates within and between strata...
Lipoprotein particle concentrations may explain the absence of coronary protection in the women's health initiative hormone trialsJudith Hsia
Department of Medicine, George Washington University, Washington, DC, USA
Arterioscler Thromb Vasc Biol 28:1666-71. 2008..In an effort to explain this finding, we examined lipoprotein particle concentrations and their interactions with hormone therapy in a case-control substudy...
Coronary artery calcification in black women and white womenCharanjit Khurana
Division of Cardiology, The George Washington University, Washington, DC, USA
Am Heart J 145:724-9. 2003..Ethnicity was not an independent predictor of coronary calcification...
Sudden cardiac death in patients with stable coronary artery disease and preserved left ventricular systolic functionJudith Hsia
Department of Medicine, George Washington University, Washington, DC, USA
Am J Cardiol 101:457-61. 2008..Thus, among patients with stable CAD with preserved left ventricular systolic function receiving current standard-of-care including coronary revascularization, clinical characteristics can identify individuals at higher risk for SCD...
Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trialGarnet L Anderson
Fred Hutchinson Cancer Research Center, Seattle, Wash 98109 1024, USA
JAMA 291:1701-12. 2004..Despite decades of use and considerable research, the role of estrogen alone in preventing chronic diseases in postmenopausal women remains uncertain...
Prognostic significance of the Centers for Disease Control/American Heart Association high-sensitivity C-reactive protein cut points for cardiovascular and other outcomes in patients with stable coronary artery diseaseMarc S Sabatine
Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
Circulation 115:1528-36. 2007....
Estrogen therapy and coronary-artery calcificationJoAnn E Manson
Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
N Engl J Med 356:2591-602. 2007..We examined the relationship between estrogen therapy and coronary-artery calcium in the context of a randomized clinical trial...
Calcium plus vitamin D supplementation and the risk of fracturesRebecca D Jackson
Division of Endocrinology, Ohio State University, 485 McCampbell, 1581 Dodd Dr, Columbus, OH 43210, USA
N Engl J Med 354:669-83. 2006..The efficacy of calcium with vitamin D supplementation for preventing hip and other fractures in healthy postmenopausal women remains equivocal...
Relation of demographic factors, menstrual history, reproduction and medication use to sex hormone levels in postmenopausal womenAnne McTiernan
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Breast Cancer Res Treat 108:217-31. 2008..These results suggest that while age, oophorectomy status, and NSAID use may be associated with selected sex hormone concentrations, few menstrual or reproductive factors affect endogenous sex hormones in the postmenopausal period...
Resting heart rate as a low tech predictor of coronary events in women: prospective cohort studyJudith Hsia
George Washington University, Washington, DC 20037, USA
BMJ 338:b219. 2009..To evaluate resting heart rate as an independent predictor of cardiovascular risk in women...
Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II)Deborah Grady
Department of Epidemiology and Biostatistics, University of California, San Francisco, 74 New Montgomery St, Suite 600, San Francisco, CA 94105, USA
JAMA 288:49-57. 2002..However, in the hormone group, findings did suggest a higher risk of CHD events during the first year, and a decreased risk during years 3 to 5...
Remnant-like lipoproteins, hormone therapy, and angiographic and clinical outcomes: the Women's Angiographic Vitamin & Estrogen TrialVera Bittner
University of Alabama at Birmingham, 35294, USA
Am Heart J 148:293-9. 2004....
A prospective study of the effect of hypertension and baseline blood pressure on cognitive decline and dementia in postmenopausal women: the Women's Health Initiative Memory StudyKaren C Johnson
Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, Tennesse 38163, USA
J Am Geriatr Soc 56:1449-58. 2008..To examine the relationship between baseline hypertension, blood pressure, and the development of cognitive decline in participants in the Women's Health Initiative Memory Study (WHIMS)...
Prognostic value of B-Type natriuretic peptides in patients with stable coronary artery disease: the PEACE TrialTorbjørn Omland
Department of Medicine, Akershus University Hospital, Lorenskog, Norway
J Am Coll Cardiol 50:205-14. 2007....
Estrogen plus progestin and the risk of coronary heart diseaseJoAnn E Manson
Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
N Engl J Med 349:523-34. 2003..In this report, we provide the final results with regard to estrogen plus progestin and CHD from the Women's Health Initiative (WHI)...
Prevalence, clinical significance, and management of peripheral arterial disease in women: is there a role for postmenopausal hormone therapy?Ramesh Mazhari
Division of Cardiology, George Washington University, Washington, DC 20037, USA
Vasc Health Risk Manag 1:111-7. 2005..This review particularly focuses on the role, if any, of postmenopausal hormone therapy for prevention or treatment of PAD, which was a pre-specified secondary outcome for these three randomized trials...
Effects of estrogen with and without progestin and obesity on symptomatic gastroesophageal refluxZongli Zheng
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Gastroenterology 135:72-81. 2008..An association between female hormones and symptomatic gastroesophageal reflux disease (GERD) and may be modified by obesity is suggested but not proven. Factors affecting GERD progression, however, are largely unknown...
Calcium plus vitamin D supplementation and the risk of incident diabetes in the Women's Health InitiativeIan H De Boer
Division of Nephrology, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA
Diabetes Care 31:701-7. 2008..We examined the effect of calcium plus vitamin D supplementation on the incidence of drug-treated diabetes in postmenopausal women...
Calcium plus vitamin D supplementation and the risk of colorectal cancerJean Wactawski-Wende
Department of Social and Preventive Medicine, University at Buffalo, 270 Farber Hall, Buffalo, NY 14214, USA
N Engl J Med 354:684-96. 2006..However, randomized-trial evidence that calcium with vitamin D supplementation is beneficial in the primary prevention of colorectal cancer is lacking...
Oophorectomy, hormone therapy, and subclinical coronary artery disease in women with hysterectomy: the Women's Health Initiative coronary artery calcium studyMatthew A Allison
University of California San Diego, La Jolla, CA, USA
Menopause 15:639-47. 2008..In this study, we aimed to determine the associations between coronary artery calcium (CAC) and hysterectomy, oophorectomy, and hormone therapy use with a focus on the duration of menopause for which there was no hormone therapy use...
Renal insufficiency and the risk of lower extremity peripheral arterial disease: results from the Heart and Estrogen/Progestin Replacement Study (HERS)ANN M O'HARE
Department of Medicine, Box 111J, VA Medical Center San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA
J Am Soc Nephrol 15:1046-51. 2004..Future studies should determine whether this association is present in other populations and investigate its potential mechanisms...
Low-fat dietary pattern and risk of invasive breast cancer: the Women's Health Initiative Randomized Controlled Dietary Modification TrialRoss L Prentice
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Wash 98109, USA
JAMA 295:629-42. 2006..The hypothesis that a low-fat dietary pattern can reduce breast cancer risk has existed for decades but has never been tested in a controlled intervention trial...
Angiotensin-converting-enzyme inhibition in stable coronary artery diseaseEugene Braunwald
Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA
N Engl J Med 351:2058-68. 2004....
Hip bone density predicts breast cancer risk independently of Gail score: results from the Women's Health InitiativeZhao Chen
Division of Epidemiology and Biostatistics, University of Arizona College of Public Health, Tucson, Arizona 85724 5211, USA
Cancer 113:907-15. 2008..The objective of the current study was to investigate whether hip BMD predicts postmenopausal breast cancer risk independently of the Gail score...
Prognostic utility of lipoprotein-associated phospholipase A2 for cardiovascular outcomes in patients with stable coronary artery diseaseMarc S Sabatine
Cardiovascular Division, Brigham and Women s Hospital and Department of Medicine, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
Arterioscler Thromb Vasc Biol 27:2463-9. 2007....
Conjugated equine estrogens and global cognitive function in postmenopausal women: Women's Health Initiative Memory StudyMark A Espeland
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
JAMA 291:2959-68. 2004..The effect of estrogen-alone therapy, also evaluated in WHIMS, on cognition has not been established for this population...
Low-fat dietary pattern and risk of colorectal cancer: the Women's Health Initiative Randomized Controlled Dietary Modification TrialShirley A A Beresford
Department of Epidemiology, University of Washington, Seattle, WA 98195 7236, USA
JAMA 295:643-54. 2006..Observational studies and polyp recurrence trials are not conclusive regarding the effects of a low-fat dietary pattern on risk of colorectal cancer, necessitating a primary prevention trial...
Association between different measures of blood pressure and coronary artery calcium in postmenopausal womenMatthew A Allison
University of California San Diego, La Jolla, California, USA
Hypertension 52:833-40. 2008..03 to 2.90; P=0.04). In postmenopausal women, higher levels of pulse pressure and systolic blood pressure were strong determinants of CAC, whereas diastolic blood pressure was inversely related...
Coronary heart disease prevention in menopausal womenDaniel Schneider
George Washington University, 2150 Pennsylvania Ave NW, Washington, DC 20037, USA
Expert Opin Pharmacother 6:695-705. 2005..This paper discusses the impact of menopause on conventional risk factors and reviews gender-specific primordial, primary and secondary prevention strategies...
Depressive symptoms and heart rate variability in postmenopausal womenChin K Kim
Division of Cardiovascular Medicine, University of Florida, Gainesville 32610-0277, USA
Arch Intern Med 165:1239-44. 2005..These findings may contribute to the increased cardiac morbidity and mortality rates associated with depression in other studies...
Estrogen plus progestin and breast cancer detection by means of mammography and breast biopsyRowan T Chlebowski
Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA 90502, USA
Arch Intern Med 168:370-7; quiz 345. 2008..The effect of combined hormone therapy on breast cancer detection is not established...
Normal standards for QT and QT subintervals derived from a large ethnically diverse population of women aged 50 to 79 years (the Women's Health Initiative [WHI])Pentti M Rautaharju
Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
Am J Cardiol 97:730-7. 2006..Bazett's formula is inappropriate for testing new drugs or other applications...
Lipoprotein-associated phospholipase A2, hormone use, and the risk of ischemic stroke in postmenopausal womenSylvia Wassertheil-Smoller
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Hypertension 51:1115-22. 2008....
Women's Ischemic Syndrome Evaluation: current status and future research directions: report of the National Heart, Lung and Blood Institute workshop: October 2-4, 2002 : Section 4: lessons from hormone replacement trialsDavid D Waters
Circulation 109:e53-5. 2004
Effect of lowering LDL cholesterol substantially below currently recommended levels in patients with coronary heart disease and diabetes: the Treating to New Targets (TNT) studyJames Shepherd
Department of Vascular Biochemistry, Royal Infirmary, Glasgow G4 OSF, U K
Diabetes Care 29:1220-6. 2006..The objective of our study was to investigate whether similar benefits of high-dose intensive atorvastatin therapy can be achieved in patients with CHD and diabetes...
Calcium, vitamin D supplementation, and physical function in the Women's Health InitiativeRobert L Brunner
University of Nevada School of Medicine, PMB 251, MS 145, Reno, NV 89557, USA
J Am Diet Assoc 108:1472-9. 2008..Now we examine whether the treatment affected self-reported physical functioning and objective measures of physical functioning...
The Women's Health Initiative postmenopausal hormone trials: overview and baseline characteristics of participantsMarcia L Stefanick
Stanford Center for Research in Disease Prevention, Stanford University, Palo Alto, CA, USA
Ann Epidemiol 13:S78-86. 2003
Cystatin-C, renal function, and incidence of hip fracture in postmenopausal womenAndrea Z LaCroix
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
J Am Geriatr Soc 56:1434-41. 2008..To evaluate the association between chronic kidney disease and incident hip fracture using serum cystatin-C as a biomarker of renal function calculated without reference to muscle mass...
Low-fat dietary pattern and risk of treated diabetes mellitus in postmenopausal women: the Women's Health Initiative randomized controlled dietary modification trialLesley F Tinker
Women s Health Initiative, Fred Hutchinson Cancer Research Center, PO Box 19024, Mail Stop M3 A410, Seattle, WA 98109, USA
Arch Intern Med 168:1500-11. 2008..This study was undertaken to assess the effects of a low-fat dietary pattern on incidence of treated diabetes among generally healthy postmenopausal women...
Usefulness of baseline lipids and C-reactive protein in women receiving menopausal hormone therapy as predictors of treatment-related coronary eventsPaul F Bray
Cardeza Foundation for Hematologic Research and Jefferson Medical College, Philadelphia, Pennsylvania, USA
Am J Cardiol 101:1599-1605. 2008..However, women with favorable lipid levels, especially LDL/HDL cholesterol ratio <2.5, did not have increased risk of coronary heart disease with CEE with or without MPA irrespective of hs-CRP...
Statin use, clinical fracture, and bone density in postmenopausal women: results from the Women's Health Initiative Observational StudyAndrea Z LaCroix
Women's Health Initiative Clinical Coordinating Center, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, MP-1002, PO Box 19024, Seattle, Washington 98109-1024, USA
Ann Intern Med 139:97-104. 2003..CONCLUSION: Statin use did not improve fracture risk or bone density in the Women's Health Initiative Observational Study. The cumulative evidence does not warrant use of statins to prevent or treat osteoporosis...
Cigarette smoking and risk of benign proliferative epithelial disorders of the breast in the Women's Health InitiativeYan Cui
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Ave, Belfer 1301, Bronx, NY 10461, USA
Cancer Causes Control 18:431-8. 2007..To investigate the association between cigarette smoking and risk of benign proliferative epithelial disorders (BPED) of the breast...
Validation of self-report of rheumatoid arthritis and systemic lupus erythematosus: The Women's Health InitiativeBrian T Walitt
Georgetown University, Washington, DC, USA
J Rheumatol 35:811-8. 2008..Our objective was to determine the most effective and efficient means to validate self-reported rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) in the WHI...
Influence of albuminuria on cardiovascular risk in patients with stable coronary artery diseaseScott D Solomon
Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
Circulation 116:2687-93. 2007..We assessed the association between albuminuria and the risks for death and cardiovascular events among patients with stable coronary disease...
Panic attacks, daily life ischemia, and chest pain in postmenopausal womenJordan W Smoller
Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
Psychosom Med 68:824-32. 2006..Chest pain is a common symptom of panic attacks, but little is known about the relationship in older women among panic attacks, chest pain, and daily life ischemia...
Comparison of self-report, hospital discharge codes, and adjudication of cardiovascular events in the Women's Health InitiativeSusan R Heckbert
Department of Epidemiology, Cardiovascular Health Research Unit, University of Washington, 1730 Minor Avenue, Seattle, WA 98101 1448, USA
Am J Epidemiol 160:1152-8. 2004....
Associations between age-related nuclear cataract and lutein and zeaxanthin in the diet and serum in the Carotenoids in the Age-Related Eye Disease Study, an Ancillary Study of the Women's Health InitiativeSuzen M Moeller
Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, WI 53726 2336, USA
Arch Ophthalmol 126:354-64. 2008..To evaluate associations between nuclear cataract (determined from slitlamp photographs between May 2001 and January 2004) and lutein and zeaxanthin in the diet and serum in patients between 1994 and 1998 and macula between 2001 and 2004...
