P M Greenwood

Summary

Affiliation: George Mason University
Country: USA

Publications

  1. doi request reprint A cognitive phenotype for a polymorphism in the nicotinic receptor gene CHRNA4
    P M Greenwood
    Arch Lab, Psychology Department, George Mason University, Fairfax, VA 22030 4444, USA
    Neurosci Biobehav Rev 36:1331-41. 2012
  2. pmc Synergistic effects of genetic variation in nicotinic and muscarinic receptors on visual attention but not working memory
    P M Greenwood
    Department of Psychology, ARCH Laboratory, George Mason University, Fairfax, VA 22030, USA
    Proc Natl Acad Sci U S A 106:3633-8. 2009
  3. pmc Both a nicotinic single nucleotide polymorphism (SNP) and a noradrenergic SNP modulate working memory performance when attention is manipulated
    Pamela M Greenwood
    George Mason University, Fairfax, VA 22030 4444, USA
    J Cogn Neurosci 21:2139-53. 2009
  4. ncbi request reprint Functional plasticity in cognitive aging: review and hypothesis
    P M Greenwood
    George Mason University, Fairfax, VA 22030 4444, US
    Neuropsychology 21:657-73. 2007
  5. ncbi request reprint Scaling of visuospatial attention undergoes differential longitudinal change as a function of APOE genotype prior to old age: results from the NIMH BIOCARD study
    P M Greenwood
    Cognitive Science Laboratory, Catholic University of America, Washington, DC, and Geriatric Psychiatry Branch, National Institute of Mental Health, USA
    Neuropsychology 19:830-40. 2005
  6. pmc Specificity of the effect of a nicotinic receptor polymorphism on individual differences in visuospatial attention
    Pamela M Greenwood
    Catholic University, Washington, DC, USA
    J Cogn Neurosci 17:1611-20. 2005
  7. pmc Effects of apolipoprotein E genotype on spatial attention, working memory, and their interaction in healthy, middle-aged adults: results From the National Institute of Mental Health's BIOCARD study
    P M Greenwood
    Cognitive Science Laboratory, Catholic University of America, Washington, DC, USA
    Neuropsychology 19:199-211. 2005
  8. ncbi request reprint Alzheimer disease constricts the dynamic range of spatial attention in visual search
    R Parasuraman
    Cognitive Science Laboratory, The Catholic University of America, 250 O Boyle Hall, Washington, DC 20064, USA
    Neuropsychologia 38:1126-35. 2000
  9. ncbi request reprint Scale of attentional focus in visual search
    P M Greenwood
    Psychology Department, Catholic University of America, Washington, DC 20064, USA
    Percept Psychophys 61:837-59. 1999
  10. pmc The scaling of spatial attention in visual search and its modification in healthy aging
    P M Greenwood
    Cognitive Science Laboratory, Catholic University of America, Washington, DC 20064, USA
    Percept Psychophys 66:3-22. 2004

Detail Information

Publications22

  1. doi request reprint A cognitive phenotype for a polymorphism in the nicotinic receptor gene CHRNA4
    P M Greenwood
    Arch Lab, Psychology Department, George Mason University, Fairfax, VA 22030 4444, USA
    Neurosci Biobehav Rev 36:1331-41. 2012
    ..This hypothesis makes an important contribution to the development of cognitive phenomics by arguing for a cognitive phenotype of CHRNA4...
  2. pmc Synergistic effects of genetic variation in nicotinic and muscarinic receptors on visual attention but not working memory
    P M Greenwood
    Department of Psychology, ARCH Laboratory, George Mason University, Fairfax, VA 22030, USA
    Proc Natl Acad Sci U S A 106:3633-8. 2009
    ..Consistent with that, shifting and scaling after valid cues (tonic) were strongest in CHRNA4 C/C homozygotes who were also CHRM2 T/T homozygotes. This shows synergistic effects within the human cholinergic system...
  3. pmc Both a nicotinic single nucleotide polymorphism (SNP) and a noradrenergic SNP modulate working memory performance when attention is manipulated
    Pamela M Greenwood
    George Mason University, Fairfax, VA 22030 4444, USA
    J Cogn Neurosci 21:2139-53. 2009
    ..This evidence of an integrated cholinergic influence on working memory performance under attentional manipulation is consistent with the view that working memory and visuospatial attention are separate systems which can interact...
  4. ncbi request reprint Functional plasticity in cognitive aging: review and hypothesis
    P M Greenwood
    George Mason University, Fairfax, VA 22030 4444, US
    Neuropsychology 21:657-73. 2007
    ..The author advances the hypothesis that losses in regional brain integrity drive functional reorganization through changes in processing strategy and makes specific predictions from that hypothesis...
  5. ncbi request reprint Scaling of visuospatial attention undergoes differential longitudinal change as a function of APOE genotype prior to old age: results from the NIMH BIOCARD study
    P M Greenwood
    Cognitive Science Laboratory, Catholic University of America, Washington, DC, and Geriatric Psychiatry Branch, National Institute of Mental Health, USA
    Neuropsychology 19:830-40. 2005
    ..However, cognitive decline in midlife associated with a gene modulating neuronal response to insult argues that the concept of an AD prodrome includes factors that allow as well as cause AD...
  6. pmc Specificity of the effect of a nicotinic receptor polymorphism on individual differences in visuospatial attention
    Pamela M Greenwood
    Catholic University, Washington, DC, USA
    J Cogn Neurosci 17:1611-20. 2005
    ..The results show that normal variation in a gene controlling a nicotinic receptor makes a selective contribution to individual differences in visuospatial attention...
  7. pmc Effects of apolipoprotein E genotype on spatial attention, working memory, and their interaction in healthy, middle-aged adults: results From the National Institute of Mental Health's BIOCARD study
    P M Greenwood
    Cognitive Science Laboratory, Catholic University of America, Washington, DC, USA
    Neuropsychology 19:199-211. 2005
    ..Effects of APOE genotype on component processes of cognition in healthy, middle-aged adults is consistent with the emergence in adulthood of an APOE-epsilon4 cognitive phenotype...
  8. ncbi request reprint Alzheimer disease constricts the dynamic range of spatial attention in visual search
    R Parasuraman
    Cognitive Science Laboratory, The Catholic University of America, 250 O Boyle Hall, Washington, DC 20064, USA
    Neuropsychologia 38:1126-35. 2000
    ..The restriction in the dynamic range of spatial attention may represent an underlying component of the impairment in perceptual and memory functioning found in early-stage DAT...
  9. ncbi request reprint Scale of attentional focus in visual search
    P M Greenwood
    Psychology Department, Catholic University of America, Washington, DC 20064, USA
    Percept Psychophys 61:837-59. 1999
    ..These results go beyond current models in suggesting that visuospatial attention possesses two dynamic properties--shifting in space and varying in scale--that are deployed independently, depending on task demands...
  10. pmc The scaling of spatial attention in visual search and its modification in healthy aging
    P M Greenwood
    Cognitive Science Laboratory, Catholic University of America, Washington, DC 20064, USA
    Percept Psychophys 66:3-22. 2004
    ..The results also provided evidence that cue size effects are attentional, not strategic. This evidence is consistent with the proposed model of attentional scaling in visual search...
  11. pmc Normal genetic variation, cognition, and aging
    P M Greenwood
    Catholic University of America, USA
    Behav Cogn Neurosci Rev 2:278-306. 2003
    ....
  12. ncbi request reprint Acetylcholine affects the spatial scale of attention: evidence from Alzheimer's disease
    J A Levy
    Geriatric Psychiatry Branch, National Institute of Mental Health, USA
    Neuropsychology 14:288-98. 2000
    ..Results support a differential role for cholinergic mechanisms in the modulation of the spatial scale of visual attention...
  13. ncbi request reprint Dynamics of the spatial scale of visual attention revealed by brain event-related potentials
    Y J Luo
    Cognitive Science Laboratory, The Catholic University of America, 250 O'Boyle Hall, Washington, DC 20064, USA
    Brain Res Cogn Brain Res 12:371-81. 2001
    ....
  14. ncbi request reprint The frontal aging hypothesis evaluated
    P M Greenwood
    Cognitive Science Laboratory, Catholic University of America, Washington, DC 20064, USA
    J Int Neuropsychol Soc 6:705-26. 2000
    ..It is argued that a network-based theory of cognitive aging has advantages over the localizationist approach inherent in the frontal aging hypothesis...
  15. ncbi request reprint Age-related reduction in 3-D visual motion priming
    Y Jiang
    Cognitive Science Laboratory, Catholic University of America, USA
    Psychol Aging 14:619-26. 1999
    ..The results show that 3-D motion priming exhibits robust age-related decline. An age-related decrease in temporal persistence may account for the reduction in 3-D motion priming in older adults...
  16. pmc Beyond heritability: neurotransmitter genes differentially modulate visuospatial attention and working memory
    Raja Parasuraman
    Department of Psychology, George Mason University, 4400 University Drive, Fairfax, VA 22030 4444, USA
    Psychol Sci 16:200-7. 2005
    ..The results show that normal allelic variations in single neurotransmitter genes modulate individual differences in processing components of cognitive functions in healthy individuals...
  17. ncbi request reprint Brain mechanisms of involuntary visuospatial attention: an event-related potential study
    Shimin Fu
    Cognitive Science Laboratory, The Catholic University of America, Washington, D C, USA
    Hum Brain Mapp 25:378-90. 2005
    ..In addition, the possible feedback from higher visual cortex to the primary visual cortex is faster and occurs earlier in involuntary relative to voluntary attention task...
  18. pmc Perceptual load interacts with involuntary attention at early processing stages: event-related potential studies
    Shimin Fu
    ARCH Laboratory, Department of Psychology, George Mason University, Fairfax, VA 22030 4444, USA
    Neuroimage 48:191-9. 2009
    ....
  19. pmc Event-related potentials reveal dissociable mechanisms for orienting and focusing visuospatial attention
    Shimin Fu
    Cognitive Science Laboratory, The Catholic University of America, DC 20064, USA
    Brain Res Cogn Brain Res 23:341-53. 2005
    ..In addition, the results support the notion that voluntary and involuntary allocations of visuospatial attention are mediated by different underlying neural processes...
  20. pmc The apolipoprotein E gene, attention, and brain function
    Raja Parasuraman
    Cognitive Science Laboratory, Catholic University of America, Washington, DC 20064, USA
    Neuropsychology 16:254-74. 2002
    ....
  21. pmc Early interaction between perceptual load and involuntary attention: An event-related potential study
    Shimin Fu
    ARCH Laboratory, Department of Psychology, George Mason University, Fairfax, VA 22030 4444, USA
    Neurosci Lett 468:68-71. 2010
    ..Specifically, a high perceptual load is necessary for eliciting this earliest attentional effect on cortical processing...
  22. ncbi request reprint Interactive effects of APOE and CHRNA4 on attention and white matter volume in healthy middle-aged and older adults
    Thomas Espeseth
    University of Oslo, Oslo, Norway
    Cogn Affect Behav Neurosci 6:31-43. 2006
    ....