X Kate Zhang
Affiliation: Genzyme Corporation
- Multiplex enzyme assay screening of dried blood spots for lysosomal storage disorders by using tandem mass spectrometryX Kate Zhang
Genzyme Corporation, Framingham, MA 01701, USA
Clin Chem 54:1725-8. 2008..We modified the assay for high-throughput use in screening laboratories...
- The effect of preparation, storage and shipping of dried blood spots on the activity of five lysosomal enzymesCarole S Elbin
Genzyme Corporation, P O Box 9322, Framingham, MA 01701, United States
Clin Chim Acta 412:1207-12. 2011..The effect of DBS preparation, storage and shipping was evaluated on the activities of acid α-glucosidase, acid α-galactosidase, acid β-glucocerebrosidase, acid sphingomyelinase, and galactocerebrosidase...
- Multiplex lysosomal enzyme activity assay on dried blood spots using tandem mass spectrometryX Kate Zhang
Genzyme Corporation, Framingham, MA, USA
Methods Mol Biol 603:339-50. 2010..The mixtures of the reaction products are prepared using liquid-liquid and solid-phase extractions and quantified simultaneously using selected ion monitoring on LC-MS-MS system...
- Newborn screening for Pompe disease by measuring acid alpha-glucosidase activity using tandem mass spectrometryAngéla Dajnoki
Division of Biochemical and Paediatric Genetics, University Children s Hospital Vienna, Austria
Clin Chem 54:1624-9. 2008..We evaluated a tandem mass spectrometry (MS/MS) method to measure GAA activity for newborn screening for Pompe disease...