Wendy W Yang

Summary

Affiliation: Genzyme Corporation
Country: USA

Publications

  1. doi request reprint Relationship between neuropathology and disease progression in the SOD1(G93A) ALS mouse
    Wendy W Yang
    Genzyme Corporation, 49 New York Ave, Framingham, MA 01701 9322, USA
    Exp Neurol 227:287-95. 2011
  2. ncbi request reprint Intraparenchymal injections of acid sphingomyelinase results in regional correction of lysosomal storage pathology in the Niemann-Pick A mouse
    Wendy W Yang
    Genzyme Corporation, One Mountain Road, Framingham, MA 01701 9322, USA
    Exp Neurol 207:258-66. 2007
  3. pmc Combination brain and systemic injections of AAV provide maximal functional and survival benefits in the Niemann-Pick mouse
    Marco A Passini
    Genzyme Corporation, Framingham, MA 01701, USA
    Proc Natl Acad Sci U S A 104:9505-10. 2007

Detail Information

Publications3

  1. doi request reprint Relationship between neuropathology and disease progression in the SOD1(G93A) ALS mouse
    Wendy W Yang
    Genzyme Corporation, 49 New York Ave, Framingham, MA 01701 9322, USA
    Exp Neurol 227:287-95. 2011
    ..Hence, our findings support a role for astrocytes in modulating the progression of non-cell autonomous degeneration of motor neurons, with microglia playing a role in clearing degenerating neurons...
  2. ncbi request reprint Intraparenchymal injections of acid sphingomyelinase results in regional correction of lysosomal storage pathology in the Niemann-Pick A mouse
    Wendy W Yang
    Genzyme Corporation, One Mountain Road, Framingham, MA 01701 9322, USA
    Exp Neurol 207:258-66. 2007
    ..These results indicate that intraparenchymal injection of hASM is associated with minimal toxicity and can lead to regional reductions in storage pathology in the ASMKO mouse...
  3. pmc Combination brain and systemic injections of AAV provide maximal functional and survival benefits in the Niemann-Pick mouse
    Marco A Passini
    Genzyme Corporation, Framingham, MA 01701, USA
    Proc Natl Acad Sci U S A 104:9505-10. 2007
    ..These data demonstrate that combination therapy is a promising therapeutic modality for treating NPD and suggest a potential strategy for treating disease indications that cause both visceral and CNS pathologies...