A J McVie Wylie

Summary

Affiliation: Genzyme Corporation
Country: USA

Publications

  1. pmc Biochemical and pharmacological characterization of different recombinant acid alpha-glucosidase preparations evaluated for the treatment of Pompe disease
    A J McVie-Wylie
    Biologics Research and Development, Genzyme Corporation, One Mountain Road, Framingham, MA 01701, USA
    Mol Genet Metab 94:448-55. 2008
  2. ncbi request reprint Long-term efficacy after [E1-, polymerase-] adenovirus-mediated transfer of human acid-alpha-glucosidase gene into glycogen storage disease type II knockout mice
    E Y Ding
    Division of Medical Genetics, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
    Hum Gene Ther 12:955-65. 2001
  3. ncbi request reprint Multiple muscles in the AMD quail can be "cross-corrected" of pathologic glycogen accumulation after intravenous injection of an [E1-, polymerase-] adenovirus vector encoding human acid-alpha-glucosidase
    A J McVie-Wylie
    Division of Medical Genetics, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
    J Gene Med 5:399-406. 2003

Collaborators

  • C Rogers
  • Nina Raben
  • A J McVie-Wylie
  • E Y Ding
  • D Pressley
  • A Amalfitano
  • F K Migone
  • Y T Chen
  • D Serra
  • B L Thurberg
  • M O'Callaghan
  • X Jin
  • H Do
  • L Andrews
  • H Qiu
  • W Canfield
  • J M McPherson
  • R Gotschall
  • R J Mattaliano
  • K L Lee
  • T Kikuchi
  • T Lawson
  • M Mizutani
  • B L Hodges
  • H Hu

Detail Information

Publications3

  1. pmc Biochemical and pharmacological characterization of different recombinant acid alpha-glucosidase preparations evaluated for the treatment of Pompe disease
    A J McVie-Wylie
    Biologics Research and Development, Genzyme Corporation, One Mountain Road, Framingham, MA 01701, USA
    Mol Genet Metab 94:448-55. 2008
    ....
  2. ncbi request reprint Long-term efficacy after [E1-, polymerase-] adenovirus-mediated transfer of human acid-alpha-glucosidase gene into glycogen storage disease type II knockout mice
    E Y Ding
    Division of Medical Genetics, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
    Hum Gene Ther 12:955-65. 2001
    ..The results suggest that gene therapy strategies may have the potential to significantly improve the clinical course for GSD-II patients...
  3. ncbi request reprint Multiple muscles in the AMD quail can be "cross-corrected" of pathologic glycogen accumulation after intravenous injection of an [E1-, polymerase-] adenovirus vector encoding human acid-alpha-glucosidase
    A J McVie-Wylie
    Division of Medical Genetics, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
    J Gene Med 5:399-406. 2003
    ..We next wished to demonstrate whether this approach could be generalized across divergent species. To accomplish this goal, we determined whether a similar approach would also result in efficacy, but in a quail model of AMD...