A Joseph

Summary

Affiliation: Genzyme Corporation
Country: USA

Publications

  1. ncbi Transient low-dose methotrexate induces tolerance to murine anti-thymocyte globulin and together they promote long-term allograft survival
    Alexandra Joseph
    Investigative Clinical Immunology, Genzyme, Framingham, MA 01701, USA
    J Immunol 189:732-43. 2012
  2. ncbi Immune tolerance induction to enzyme-replacement therapy by co-administration of short-term, low-dose methotrexate in a murine Pompe disease model
    A Joseph
    Immunology Laboratory, Biologics R and D, Genzyme Corporation, Framingham, MA 01701, USA
    Clin Exp Immunol 152:138-46. 2008
  3. ncbi Identification of a cDNA for a human high-molecular-weight B-cell growth factor
    J L Ambrus
    Department of Medicine, Washington University School of Medicine, St Louis, MO 63110
    Proc Natl Acad Sci U S A 90:6330-4. 1993
  4. ncbi Antibody response to a single tetanus toxoid booster in young women in rural south India
    K Aruldas
    Department of Community Health and Development, Christian Medical College and Hospital, Vellore 632004, Tamil Nadu, India
    Natl Med J India 14:22-3. 2001
  5. ncbi The efficacy of sirolimus in the treatment of patients with refractory uveitis
    V A Shanmuganathan
    Division of Ophthalmology and Visual Science, B Floor, Eye and ENT Centre, Queens Medical Centre, Nottingham NG7 2UH, UK
    Br J Ophthalmol 89:666-9. 2005
  6. ncbi Tacrolimus immunosuppression in high-risk corneal grafts
    A Joseph
    Department of Ophthalmology, Queen s Medical Centre, Nottingham University Hospitals NHS Trust, University of Nottingham, Nottingham, UK
    Br J Ophthalmol 91:51-5. 2007
  7. ncbi Characterization and in vivo performance of dextran-spermine polyplexes and DOTAP/cholesterol lipoplexes administered locally and systemically
    H Eliyahu
    Laboratory of Membrane and Liposome Research, Department of Biochemistry, The Hebrew University, Hadassah Medical School, P O Box 12272, Jerusalem 91120, Israel
    Biomaterials 28:2339-49. 2007

Collaborators

  • Chengpei Xu
  • H Eliyahu
  • V A Shanmuganathan
  • K Aruldas
  • J P Schillemans
  • Y Barenholz
  • T Azzam
  • A J Domb
  • D Raj
  • R J Powell
  • W M Amoaku
  • H S Dua
  • E M Casely
  • E Mathai
  • V Aruldas
  • J P Muliyil
  • S Abraham
  • U Inbamalar
  • J L Ambrus
  • D Blumenthal
  • J Pippin
  • D McCourt
  • A Tamayo
  • R J Ford
  • A Srikiatchatochorn
  • K Claypool

Detail Information

Publications7

  1. ncbi Transient low-dose methotrexate induces tolerance to murine anti-thymocyte globulin and together they promote long-term allograft survival
    Alexandra Joseph
    Investigative Clinical Immunology, Genzyme, Framingham, MA 01701, USA
    J Immunol 189:732-43. 2012
    ..These data suggest that mATG and methotrexate together can provide long-term allograft survival potentially through the induction of immune tolerance...
  2. ncbi Immune tolerance induction to enzyme-replacement therapy by co-administration of short-term, low-dose methotrexate in a murine Pompe disease model
    A Joseph
    Immunology Laboratory, Biologics R and D, Genzyme Corporation, Framingham, MA 01701, USA
    Clin Exp Immunol 152:138-46. 2008
    ..A consistent expansion of peritoneal B1 B cells was observed. Control over this B1 B cell response may be part of the complex mechanism of action of methotrexate-induced immune tolerance...
  3. ncbi Identification of a cDNA for a human high-molecular-weight B-cell growth factor
    J L Ambrus
    Department of Medicine, Washington University School of Medicine, St Louis, MO 63110
    Proc Natl Acad Sci U S A 90:6330-4. 1993
    ..The identification of this cDNA will allow further studies examining physiologic roles of this cytokine. We propose to call it interleukin 14...
  4. ncbi Antibody response to a single tetanus toxoid booster in young women in rural south India
    K Aruldas
    Department of Community Health and Development, Christian Medical College and Hospital, Vellore 632004, Tamil Nadu, India
    Natl Med J India 14:22-3. 2001
    ..CONCLUSION: In areas with good maternal and child health services, a single booster dose of tetanus toxoid can be considered adequate for primigravidae with a history of childhood immunization...
  5. ncbi The efficacy of sirolimus in the treatment of patients with refractory uveitis
    V A Shanmuganathan
    Division of Ophthalmology and Visual Science, B Floor, Eye and ENT Centre, Queens Medical Centre, Nottingham NG7 2UH, UK
    Br J Ophthalmol 89:666-9. 2005
    ..Further studies are required to establish the long term efficacy and safety of sirolimus alone or in combination with other steroid sparing immunosuppressants...
  6. ncbi Tacrolimus immunosuppression in high-risk corneal grafts
    A Joseph
    Department of Ophthalmology, Queen s Medical Centre, Nottingham University Hospitals NHS Trust, University of Nottingham, Nottingham, UK
    Br J Ophthalmol 91:51-5. 2007
    ..Systemic immunosuppression reduces the risk of rejection in high-risk corneal grafts...
  7. ncbi Characterization and in vivo performance of dextran-spermine polyplexes and DOTAP/cholesterol lipoplexes administered locally and systemically
    H Eliyahu
    Laboratory of Membrane and Liposome Research, Department of Biochemistry, The Hebrew University, Hadassah Medical School, P O Box 12272, Jerusalem 91120, Israel
    Biomaterials 28:2339-49. 2007
    ..Using chemically modified D-SPM, we demonstrated the importance of high density of positive charges and a sufficient level of secondary amines for achieving efficient transgene expression in vivo...