C Jiang

Summary

Affiliation: Genzyme Corporation
Country: USA

Publications

  1. ncbi request reprint Restoration of cyclic adenosine monophosphate-stimulated chloride channel activity in human cystic fibrosis tracheobronchial submucosal gland cells by adenovirus-mediated and cationic lipid-mediated gene transfer
    C Jiang
    Genzyme Corporation, Framingham, Massachusetts 01701 9322, USA
    Am J Respir Cell Mol Biol 20:1107-15. 1999
  2. ncbi request reprint Fas ligand/Fas-mediated apoptosis in human coronary artery smooth muscle cells: therapeutic implications of fratricidal mode of action
    A J Belanger
    Genzyme Corporation, 31 New York Avenue, Framingham, MA 01701, USA
    Cardiovasc Res 51:749-61. 2001
  3. pmc Adenovirus-mediated persistent cystic fibrosis transmembrane conductance regulator expression in mouse airway epithelium
    A Scaria
    Genzyme Corporation, Framingham, Massachusetts 01701, USA
    J Virol 72:7302-9. 1998
  4. ncbi request reprint Partial correction of defective Cl(-) secretion in cystic fibrosis epithelial cells by an analog of squalamine
    C Jiang
    Genzyme Corporation, Framingham, Massachusetts 01701-9322, USA
    Am J Physiol Lung Cell Mol Physiol 281:L1164-72. 2001
  5. ncbi request reprint Increased contact time improves adenovirus-mediated CFTR gene transfer to nasal epithelium of CF mice
    C Jiang
    Genzyme Corporation, Framingham, MA 01701 9322, USA
    Hum Gene Ther 8:671-80. 1997
  6. ncbi request reprint Enhancement of Fas ligand-induced inhibition of neointimal formation in rabbit femoral and iliac arteries by coexpression of p35
    Z Luo
    Genzyme Corporation, 31 New York Avenue, Framingham, MA 01701, USA
    Hum Gene Ther 12:2191-202. 2001
  7. ncbi request reprint Gene therapy progress and prospects: therapeutic angiogenesis for ischemic cardiovascular disease
    K A Vincent
    Genzyme Corporation, Framingham, MA 01701 9322, USA
    Gene Ther 14:781-9. 2007

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Restoration of cyclic adenosine monophosphate-stimulated chloride channel activity in human cystic fibrosis tracheobronchial submucosal gland cells by adenovirus-mediated and cationic lipid-mediated gene transfer
    C Jiang
    Genzyme Corporation, Framingham, Massachusetts 01701 9322, USA
    Am J Respir Cell Mol Biol 20:1107-15. 1999
    ..These data show that although the mechanisms of transfection may be different between the two cell types, 6CFSMEO cells are as susceptible as CFT1 cells to transfection by adenoviral and cationic-lipid gene transfer vectors...
  2. ncbi request reprint Fas ligand/Fas-mediated apoptosis in human coronary artery smooth muscle cells: therapeutic implications of fratricidal mode of action
    A J Belanger
    Genzyme Corporation, 31 New York Avenue, Framingham, MA 01701, USA
    Cardiovasc Res 51:749-61. 2001
    ....
  3. pmc Adenovirus-mediated persistent cystic fibrosis transmembrane conductance regulator expression in mouse airway epithelium
    A Scaria
    Genzyme Corporation, Framingham, Massachusetts 01701, USA
    J Virol 72:7302-9. 1998
    ..These results suggest that long-term expression of hCFTR is possible in the airway epithelia of immunocompetent mice without radical modification of Ad vector and in spite of the presence of CTLs...
  4. ncbi request reprint Partial correction of defective Cl(-) secretion in cystic fibrosis epithelial cells by an analog of squalamine
    C Jiang
    Genzyme Corporation, Framingham, Massachusetts 01701-9322, USA
    Am J Physiol Lung Cell Mol Physiol 281:L1164-72. 2001
    ..Together, these results demonstrate that in CF airway epithelial cells, administration of GL-172 is capable of partially correcting the defective Cl(-) secretion...
  5. ncbi request reprint Increased contact time improves adenovirus-mediated CFTR gene transfer to nasal epithelium of CF mice
    C Jiang
    Genzyme Corporation, Framingham, MA 01701 9322, USA
    Hum Gene Ther 8:671-80. 1997
    ..Therefore, strategies that improve internalization of viral vectors and that prolong their contact time with target cells may result in the improved clinical efficacy of such vectors...
  6. ncbi request reprint Enhancement of Fas ligand-induced inhibition of neointimal formation in rabbit femoral and iliac arteries by coexpression of p35
    Z Luo
    Genzyme Corporation, 31 New York Avenue, Framingham, MA 01701, USA
    Hum Gene Ther 12:2191-202. 2001
    ..These data suggest that coexpression of p35 in FasL-transduced VSM cells is more potent at inhibiting neointimal formation and as such represents an improved gene therapy approach for restenosis...
  7. ncbi request reprint Gene therapy progress and prospects: therapeutic angiogenesis for ischemic cardiovascular disease
    K A Vincent
    Genzyme Corporation, Framingham, MA 01701 9322, USA
    Gene Ther 14:781-9. 2007
    ..These agents are now beginning to be evaluated in clinical trials for patients with advanced ischemic cardiac and peripheral vascular disease...