D Armentano

Summary

Affiliation: Genzyme Corporation
Country: USA

Publications

  1. pmc E4ORF3 requirement for achieving long-term transgene expression from the cytomegalovirus promoter in adenovirus vectors
    D Armentano
    Genzyme Corporation, Framingham, Massachusetts 01701 9322, USA
    J Virol 73:7031-4. 1999
  2. ncbi request reprint Characterization of an adenovirus gene transfer vector containing an E4 deletion
    D Armentano
    Genzyme Corporation, Framingham, MA 01701, USA
    Hum Gene Ther 6:1343-53. 1995
  3. ncbi request reprint Increased duration of transgene expression in the lung with plasmid DNA vectors harboring adenovirus E4 open reading frame 3
    N S Yew
    Genzyme Corporation, Framingham, MA 01701 9322, USA
    Hum Gene Ther 10:1833-43. 1999
  4. pmc Novel role for E4 region genes in protection of adenovirus vectors from lysis by cytotoxic T lymphocytes
    J M Kaplan
    Genzyme Corporation, Framingham, Massachusetts 01701 9322, USA
    J Virol 73:4489-92. 1999
  5. ncbi request reprint Ectopic expression of glucagon-like peptide 1 for gene therapy of type II diabetes
    G B Parsons
    Department of Molecular Biology, Genzyme Corporation, Framingham, MA 01701, USA
    Gene Ther 14:38-48. 2007
  6. ncbi request reprint Adenovirus-mediated gene transfer to orthotopic hepatocellular carcinomas in athymic nude mice
    S K Yoon
    Molecular Hepatology Laboratory, Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts, USA
    Cancer Gene Ther 8:573-9. 2001
  7. doi request reprint Direct comparison of hepatocyte-specific expression cassettes following adenoviral and nonviral hydrodynamic gene transfer
    F Jacobs
    Molecular and Cardiovascular Medicine, Center for Molecular and Vascular Biology, University of Leuven, Leuven, Belgium
    Gene Ther 15:594-603. 2008

Collaborators

Detail Information

Publications7

  1. pmc E4ORF3 requirement for achieving long-term transgene expression from the cytomegalovirus promoter in adenovirus vectors
    D Armentano
    Genzyme Corporation, Framingham, Massachusetts 01701 9322, USA
    J Virol 73:7031-4. 1999
    ..CMV promoter truncation led to the persistence of expression in the absence of E4, thus eliminating the ORF3 requirement...
  2. ncbi request reprint Characterization of an adenovirus gene transfer vector containing an E4 deletion
    D Armentano
    Genzyme Corporation, Framingham, MA 01701, USA
    Hum Gene Ther 6:1343-53. 1995
    ..We describe the inclusion of the A2E4ORF6 modification in a recombinant adenovirus vector, Ad2/CFTR-2, for gene transfer of the human cystic fibrosis transmembrane regulator (CFTR)...
  3. ncbi request reprint Increased duration of transgene expression in the lung with plasmid DNA vectors harboring adenovirus E4 open reading frame 3
    N S Yew
    Genzyme Corporation, Framingham, MA 01701 9322, USA
    Hum Gene Ther 10:1833-43. 1999
    ....
  4. pmc Novel role for E4 region genes in protection of adenovirus vectors from lysis by cytotoxic T lymphocytes
    J M Kaplan
    Genzyme Corporation, Framingham, Massachusetts 01701 9322, USA
    J Virol 73:4489-92. 1999
    ..Elements from both the E3 and the E4 regions were required for this effect, leading to the identification of a previously undescribed role for E4 gene products in resistance to cytolysis...
  5. ncbi request reprint Ectopic expression of glucagon-like peptide 1 for gene therapy of type II diabetes
    G B Parsons
    Department of Molecular Biology, Genzyme Corporation, Framingham, MA 01701, USA
    Gene Ther 14:38-48. 2007
    ..These results demonstrate the feasibility of gene therapy for type II diabetes using GLP-1 expression vectors...
  6. ncbi request reprint Adenovirus-mediated gene transfer to orthotopic hepatocellular carcinomas in athymic nude mice
    S K Yoon
    Molecular Hepatology Laboratory, Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts, USA
    Cancer Gene Ther 8:573-9. 2001
    ..However, due to the observed transduction of disseminated hepatocytes following intratumoral administration, additional HCC-specific targeting to further enhance the safety of adenoviral vectors may be required...
  7. doi request reprint Direct comparison of hepatocyte-specific expression cassettes following adenoviral and nonviral hydrodynamic gene transfer
    F Jacobs
    Molecular and Cardiovascular Medicine, Center for Molecular and Vascular Biology, University of Leuven, Leuven, Belgium
    Gene Ther 15:594-603. 2008
    ....