Viatcheslav R Akmaev

Summary

Affiliation: Genzyme Corporation
Country: USA

Publications

  1. ncbi request reprint Correction of sequence-based artifacts in serial analysis of gene expression
    Viatcheslav R Akmaev
    Genzyme Corporation, Framingham, MA 01701 9322, USA
    Bioinformatics 20:1254-63. 2004
  2. ncbi request reprint Correction of technology-related artifacts in serial analysis of gene expression
    Viatcheslav R Akmaev
    Bioinformatics, Genzyme Corporation, Framingham, MA, USA
    Methods Mol Biol 387:133-42. 2008
  3. ncbi request reprint Identification of genes potentially involved in the acquisition of androgen-independent and metastatic tumor growth in an autochthonous genetically engineered mouse prostate cancer model
    Sharon D Morgenbesser
    Department of Oncology Research, Genzyme Corporation, Framingham, MA 01701 9322, USA
    Prostate 67:83-106. 2007
  4. pmc Vascular gene expression in nonneoplastic and malignant brain
    Stephen L Madden
    Genetics and Genomics, 5 Mountain Rd, Framingham, MA 01701, USA
    Am J Pathol 165:601-8. 2004
  5. ncbi request reprint New insights into ADPKD molecular pathways using combination of SAGE and microarray technologies
    Herve Husson
    Functional Genomics, Genzyme Corporation, Framingham, MA 01701 9322, USA
    Genomics 84:497-510. 2004

Collaborators

Detail Information

Publications5

  1. ncbi request reprint Correction of sequence-based artifacts in serial analysis of gene expression
    Viatcheslav R Akmaev
    Genzyme Corporation, Framingham, MA 01701 9322, USA
    Bioinformatics 20:1254-63. 2004
    ..By virtue of their low-random incidence, such tag errors have minimal impact on differential expression analysis. However, to fully exploit the value of large SAGE tag datasets, it is desirable to account for and correct tag artifacts...
  2. ncbi request reprint Correction of technology-related artifacts in serial analysis of gene expression
    Viatcheslav R Akmaev
    Bioinformatics, Genzyme Corporation, Framingham, MA, USA
    Methods Mol Biol 387:133-42. 2008
    ..The ditag processing step is essential for calculation of unbiased tag numbers, and the tag processing step allows for filtration of tag sequence artifacts and adjustment of tag numbers...
  3. ncbi request reprint Identification of genes potentially involved in the acquisition of androgen-independent and metastatic tumor growth in an autochthonous genetically engineered mouse prostate cancer model
    Sharon D Morgenbesser
    Department of Oncology Research, Genzyme Corporation, Framingham, MA 01701 9322, USA
    Prostate 67:83-106. 2007
    ..A major focus of prostate cancer research has been to identify genes that are deregulated during tumor progression, potentially providing diagnostic markers and therapeutic targets...
  4. pmc Vascular gene expression in nonneoplastic and malignant brain
    Stephen L Madden
    Genetics and Genomics, 5 Mountain Rd, Framingham, MA 01701, USA
    Am J Pathol 165:601-8. 2004
    ..Additional characterization of this extensive brain endothelial cell gene expression database will provide unique molecular insights into vascular gene expression...
  5. ncbi request reprint New insights into ADPKD molecular pathways using combination of SAGE and microarray technologies
    Herve Husson
    Functional Genomics, Genzyme Corporation, Framingham, MA 01701 9322, USA
    Genomics 84:497-510. 2004
    ..01. This study may provide valuable insights into the pathophysiology of ADPKD and suggest potential therapeutic targets...