Research Topics
| Chunlei WuSummaryAffiliation: Genomics Institute of the Novartis Research Foundation Country: USA Publications
| Collaborators
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Detail Information
Publications
BioGPS: an extensible and customizable portal for querying and organizing gene annotation resourcesChunlei Wu
Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Dr, San Diego, CA 92121, USA
Genome Biol 10:R130. 2009..gnf.org, a centralized gene portal for aggregating distributed gene annotation resources. Moreover, BioGPS embraces the principle of community intelligence, enabling any user to easily and directly contribute to the BioGPS platform...
Gene set enrichment in eQTL data identifies novel annotations and pathway regulatorsChunlei Wu
Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America
PLoS Genet 4:e1000070. 2008..We believe that the specific molecular hypotheses generated in this study will reveal many additional pathway members and regulators, and that the analysis approaches described herein will be broadly applicable to other eQTL data sets...
A gene wiki for community annotation of gene functionJon W Huss
San Diego State University, Bioinformatics and Medical Informatics Graduate Program, San Diego, California, USA
PLoS Biol 6:e175. 2008
TCLUST: a fast method for clustering genome-scale expression dataBanu Dost
Department of Computer Science and Engineering, University of California, San Diego, CA 92093, USA
IEEE/ACM Trans Comput Biol Bioinform 8:808-18. 2011..Source code for TCLUST is downloadable at http://www.cse.ucsd.edu/~bdost/tclust.)..
CAFET algorithm reveals Wnt/PCP signature in lung squamous cell carcinomaYue Hu
Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America
PLoS ONE 6:e25807. 2011..Our results suggest that SCC and AC utilize different branches of the Wnt pathway during oncogenesis...
Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAPEric Miller
Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, USA
Chem Biol 19:955-62. 2012..These results revealed potent small molecule regulators of YAP and suggest that S1P and LPA might modulate cell proliferation and tumorigenesis through YAP activation...
Genomewide association analysis in diverse inbred mice: power and population structurePhillip McClurg
Genomics Institute of the Novartis Research Foundation, San Diego, California 92121, USA
Genetics 176:675-83. 2007..These eQTL data confirmed that the MDP is a suitable mapping population for QTL discovery and that eQTL results can serve as a gold standard for relative measures of statistical power...
Short oligonucleotide probes containing G-stacks display abnormal binding affinity on Affymetrix microarraysChunlei Wu
Genomic Institute of Novartis Research Foundation, 10675 John Jay Hopkins Dr, San Diego, CA 92121, USA
Bioinformatics 23:2566-72. 2007..Our findings are expected to be useful in microarray design and data analysis...
