Pedro Aza Blanc

Summary

Affiliation: Genomics Institute of the Novartis Research Foundation
Country: USA

Publications

  1. ncbi request reprint RNAi and HTS: exploring cancer by systematic loss-of-function
    Aarron T Willingham
    Department of Chemistry, Scripps Research Institute, 10550 N Torrey Pines Road, La Jolla, CA 92093, USA
    Oncogene 23:8392-400. 2004
  2. ncbi request reprint Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening
    Pedro Aza-Blanc
    Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA
    Mol Cell 12:627-37. 2003
  3. ncbi request reprint Exposing oncogenic dependencies for cancer drug target discovery and validation using RNAi
    Quinn L Deveraux
    The Genomics Institute of Novartis Research Institute Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA
    Semin Cancer Biol 13:293-300. 2003
  4. pmc Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle
    Yan Guo Ren
    Department of Cancer Biology, Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, USA
    Mol Biol Cell 15:5064-74. 2004
  5. ncbi request reprint PTPome-wide functional RNA interference screening methods
    Amanda M Opaluch
    Burnham Institute for Medical Research, 10901 N Torrey Pines Road, La Jolla, CA 92037, USA
    Methods 42:306-12. 2007

Collaborators

  • Quinn L Deveraux
  • Garret M Hampton
  • Lutz Tautz
  • Pedro Aza-Blanc
  • Amanda M Opaluch
  • Aarron T Willingham
  • Yan Guo Ren
  • Loribelle Milan
  • Torkel Vang
  • Tomas Mustelin
  • Scott Williams
  • Deborah A Knee
  • Marc Nasoff
  • Klaus W Wagner
  • Christopher L Cooper
  • Michael P Cooke
  • Klaus Wagner
  • Serge Batalov

Detail Information

Publications5

  1. ncbi request reprint RNAi and HTS: exploring cancer by systematic loss-of-function
    Aarron T Willingham
    Department of Chemistry, Scripps Research Institute, 10550 N Torrey Pines Road, La Jolla, CA 92093, USA
    Oncogene 23:8392-400. 2004
    ....
  2. ncbi request reprint Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening
    Pedro Aza-Blanc
    Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA
    Mol Cell 12:627-37. 2003
    ..Collectively, these observations offer several insights on how TRAIL mediates the selective killing of tumor cells and demonstrate the utility of large-scale RNAi screens in mammalian cells...
  3. ncbi request reprint Exposing oncogenic dependencies for cancer drug target discovery and validation using RNAi
    Quinn L Deveraux
    The Genomics Institute of Novartis Research Institute Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA
    Semin Cancer Biol 13:293-300. 2003
    ....
  4. pmc Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle
    Yan Guo Ren
    Department of Cancer Biology, Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, USA
    Mol Biol Cell 15:5064-74. 2004
    ....
  5. ncbi request reprint PTPome-wide functional RNA interference screening methods
    Amanda M Opaluch
    Burnham Institute for Medical Research, 10901 N Torrey Pines Road, La Jolla, CA 92037, USA
    Methods 42:306-12. 2007
    ..We also discuss the suitability of this technology for further assay development and application to other functional read-outs and signaling pathways...