Genomes and Genes
Affiliation: Genentech Inc
- WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumorsD Pennica
Department of Molecular Oncology, Genentech Inc, 1 DNA Way, South San Francisco, CA 94080, USA
Proc Natl Acad Sci U S A 95:14717-22. 1998..These results suggest that the WISP genes may be downstream of Wnt-1 signaling and that aberrant levels of WISP expression in colon cancer may play a role in colon tumorigenesis...
- Identification of Wnt responsive genes using a murine mammary epithelial cell line model systemLisa Taneyhill
Division of Biology, California Institute of Technology, Pasadena, CA, USA
BMC Dev Biol 4:6. 2004..Over the past years, several genes have been identified as Wnt responsive, including c-myc, siamois, and cyclin D1...
- Synergistic induction of tumor antigens by Wnt-1 signaling and retinoic acid revealed by gene expression profilingDavid A Tice
Department of Molecular Oncology, Genentech Inc, South San Francisco, California 94080, USA
J Biol Chem 277:14329-35. 2002..In principal, the therapeutic index of antibodies directed against these antigens should be enhanced by co-administration of retinoic acid...