John G Monroe

Summary

Affiliation: Genentech Inc
Country: USA

Publications

  1. ncbi Bridging Toll-like- and B cell-receptor signaling: meet me at the autophagosome
    John G Monroe
    Genentech, Inc, 1 DNA Way, MS 93b, South San Francisco, CA 94080, USA
    Immunity 28:729-31. 2008
  2. ncbi Incomplete activation of CD4 T cells by antigen-presenting transitional immature B cells: implications for peripheral B and T cell responsiveness
    James B Chung
    Division of Rheumatology, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Immunol 171:1758-67. 2003
  3. ncbi Basal B-cell receptor signaling in B lymphocytes: mechanisms of regulation and role in positive selection, differentiation, and peripheral survival
    Ezequiel M Fuentes-Panana
    Department of Pathology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Immunol Rev 197:26-40. 2004
  4. ncbi Ligand-independent tonic signaling in B-cell receptor function
    John G Monroe
    University of Pennsylvania School of Medicine, 421 Curie Boulevard, Philadelphia, Pennsylvania 191104, USA
    Curr Opin Immunol 16:288-95. 2004
  5. ncbi B cell activator PAX5 promotes lymphomagenesis through stimulation of B cell receptor signaling
    Diana Cozma
    Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6051, USA
    J Clin Invest 117:2602-10. 2007

Collaborators

  • Diana Cozma
  • Ezequiel M Fuentes-Panana
  • James B Chung
  • Suchita Hodawadekar
  • Michael L Atchison
  • Michele H Metzgar
  • Duonan Yu
  • Shannon Grande
  • Anna Azvolinsky
  • Andrei Thomas-Tikhonenko
  • Jan Erikson
  • John W Tobias
  • Jennifer Paterson
  • Teresa Marafioti
  • Gregory Bannish
  • Scott Adler
  • Anand Jacob
  • Andrew D Wells
  • Laurence A Turka

Detail Information

Publications5

  1. ncbi Bridging Toll-like- and B cell-receptor signaling: meet me at the autophagosome
    John G Monroe
    Genentech, Inc, 1 DNA Way, MS 93b, South San Francisco, CA 94080, USA
    Immunity 28:729-31. 2008
    ..In their model, B cell-receptor signaling induces the fusion of Toll-like receptor 9 (TLR9)-containing endosomes with internalized signaling-competent BCR into autophagosomes...
  2. ncbi Incomplete activation of CD4 T cells by antigen-presenting transitional immature B cells: implications for peripheral B and T cell responsiveness
    James B Chung
    Division of Rheumatology, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Immunol 171:1758-67. 2003
    ....
  3. ncbi Basal B-cell receptor signaling in B lymphocytes: mechanisms of regulation and role in positive selection, differentiation, and peripheral survival
    Ezequiel M Fuentes-Panana
    Department of Pathology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Immunol Rev 197:26-40. 2004
    ..However, long-term survival and formation of specific mature B-cell populations may be dependent on ligand-receptor interactions...
  4. ncbi Ligand-independent tonic signaling in B-cell receptor function
    John G Monroe
    University of Pennsylvania School of Medicine, 421 Curie Boulevard, Philadelphia, Pennsylvania 191104, USA
    Curr Opin Immunol 16:288-95. 2004
    ..The potential co-existence of tonic and induced signaling suggests a unique aspect of BCR complexes, or at least an aspect of receptors that has previously been under-appreciated...
  5. ncbi B cell activator PAX5 promotes lymphomagenesis through stimulation of B cell receptor signaling
    Diana Cozma
    Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6051, USA
    J Clin Invest 117:2602-10. 2007
    ..Thus, stimulation of neoplastic growth by Pax5 occurs through BCR and is sensitive to genetic and pharmacological inhibitors of this pathway...