Amitabha Chaudhuri

Summary

Affiliation: Genentech Inc
Country: USA

Publications

  1. ncbi Protein-interaction mapping in search of effective drug targets
    Amitabha Chaudhuri
    Department of Molecular Biology, Genentech Inc, South San Francisco, CA 94080, USA
    Bioessays 27:958-69. 2005
  2. pmc Distinct involvement of the Gab1 and Grb2 adaptor proteins in signal transduction by the related receptor tyrosine kinases RON and MET
    Amitabha Chaudhuri
    Department of Molecular Oncology, Genentech, Inc, South San Francisco, California 94080, USA
    J Biol Chem 286:32762-74. 2011
  3. doi Proteolytic activation of pro-macrophage-stimulating protein by hepsin
    Rajkumar Ganesan
    Department of Early Discovery Biochemistry, Genentech, Inc, 1 DNA Way, MS 27, South San Francisco, CA 94080, USA
    Mol Cancer Res 9:1175-86. 2011
  4. pmc Host genetic background impacts modulation of the TLR4 pathway by RON in tissue-associated macrophages
    Amitabha Chaudhuri
    Department of Molecular Oncology, Genentech Inc, South San Francisco, CA 94080, USA
    Immunol Cell Biol 91:451-60. 2013
  5. ncbi Gaining confidence in high-throughput protein interaction networks
    Joel S Bader
    Department of Biomedical Engineering, 201C Clark Hall, Johns Hopkins University, 3400 N Charles St, Baltimore, Maryland 21218, USA
    Nat Biotechnol 22:78-85. 2004

Collaborators

  • Joel S Bader
  • Rajkumar Ganesan
  • S Jack Lin
  • Robert A Lazarus
  • Lydia Santell
  • Ming Hong Xie
  • Ganesh A Kolumam
  • Thomas D Wu
  • Daniel Kirchhofer

Detail Information

Publications5

  1. ncbi Protein-interaction mapping in search of effective drug targets
    Amitabha Chaudhuri
    Department of Molecular Biology, Genentech Inc, South San Francisco, CA 94080, USA
    Bioessays 27:958-69. 2005
    ..The review discusses challenges and breakthroughs in this new and evolving area and its impact on medicine...
  2. pmc Distinct involvement of the Gab1 and Grb2 adaptor proteins in signal transduction by the related receptor tyrosine kinases RON and MET
    Amitabha Chaudhuri
    Department of Molecular Oncology, Genentech, Inc, South San Francisco, California 94080, USA
    J Biol Chem 286:32762-74. 2011
    ..Hence, RON and MET differ in their adaptor interactions; furthermore, Grb2 performs a novel antagonistic role in the context of RON signaling...
  3. doi Proteolytic activation of pro-macrophage-stimulating protein by hepsin
    Rajkumar Ganesan
    Department of Early Discovery Biochemistry, Genentech, Inc, 1 DNA Way, MS 27, South San Francisco, CA 94080, USA
    Mol Cancer Res 9:1175-86. 2011
    ..These findings suggest that the MSP/RON signaling pathway may be regulated by hepsin in tissue homeostasis and in disease pathologies, such as in cancer and immune disorders...
  4. pmc Host genetic background impacts modulation of the TLR4 pathway by RON in tissue-associated macrophages
    Amitabha Chaudhuri
    Department of Molecular Oncology, Genentech Inc, South San Francisco, CA 94080, USA
    Immunol Cell Biol 91:451-60. 2013
    ..These findings provide novel insight into the complex interplay between genetic context and immune function. ..
  5. ncbi Gaining confidence in high-throughput protein interaction networks
    Joel S Bader
    Department of Biomedical Engineering, 201C Clark Hall, Johns Hopkins University, 3400 N Charles St, Baltimore, Maryland 21218, USA
    Nat Biotechnol 22:78-85. 2004
    ..The type of analysis presented will be essential for analyzing the growing amount of genomic and proteomics data in model organisms and humans...