- Increasing parvovirus filter throughput of monoclonal antibodies using ion exchange membrane adsorptive pre-filtrationArick Brown
Process Research and Development, Genentech, 1 DNA Way, South San Francisco, California 94080, USA
Biotechnol Bioeng 106:627-37. 2010..This study's significance lies in a previously undiscovered application of membrane chromatography, leading to a more cost effective and robust approach to parvovirus filtration for the production of monoclonal antibodies...
- Overloading ion-exchange membranes as a purification step for monoclonal antibodiesArick Brown
Process Technical Development, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA
Biotechnol Appl Biochem 56:59-70. 2010..The importance of the present study lies in our demonstration of an alternative use of ion-exchange membranes for fast, effective and high yielding purification of mAbs...