Research Topics
Genomes and Genes | Michael A ChernousovSummaryAffiliation: Geisinger Medical Center Country: USA Publications
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Publications
alphaVbeta8 integrin is a Schwann cell receptor for fibrinMichael A Chernousov
Weis Center for Research, Geisinger Clinic, 100 North Academy Ave, Danville, PA 17822, USA
Exp Cell Res 291:514-24. 2003..Taken together, these results strongly suggest that alphaVbeta8 integrin is a Schwann cell receptor for fibrin...
Alpha7beta1 integrin is a receptor for laminin-2 on Schwann cellsMichael A Chernousov
Weis Center for Research, Geisinger Clinic, Danville, Pennsylvania, USA
Glia 55:1134-44. 2007..These findings strongly suggest that alpha7beta1 integrin is a Schwann cell receptor for laminin-2 that provides transmembrane linkage between the Schwann cell basal lamina and cytoskeleton...
Fibrillin-2 is dispensable for peripheral nerve development, myelination and regenerationMichael A Chernousov
Weis Center for Research, Geisinger Clinic, 100 North Academy Avenue, Danville, PA 17822 2613, USA
Matrix Biol 29:357-68. 2010..Based on the data obtained we can conclude that peripheral neuropathy should be excluded as the cause of the impairment of locomotory function and joint contractures observed in fibrillin-2 deficient animals...
Glypican-1 and alpha4(V) collagen are required for Schwann cell myelinationMichael A Chernousov
Weis Center for Research, Geisinger Clinic, Danville, Pennsylvania 17822 2601, USA
J Neurosci 26:508-17. 2006..Suppression of glypican-1 or alpha4(V) collagen expression significantly inhibited myelination. These results demonstrate an important role for these proteins in peripheral nerve terminal differentiation...
Regulation of Schwann cell function by the extracellular matrixMichael A Chernousov
Weis Center for Research, Geisinger Clinic, Danville, Pennsylvania, USA
Glia 56:1498-507. 2008..In this article, we will review the recent advances in the studies of laminin and collagen function in Schwann cell development...
Schwann cell adhesion to a novel heparan sulfate binding site in the N-terminal domain of alpha 4 type V collagen is mediated by syndecan-3Robert Erdman
Sigfried and Janet Weis Center for Research, Geisinger Clinic, 100 North Academy Avenue, Danville, PA 17822, USA
J Biol Chem 277:7619-25. 2002..Together, these results suggest that Schwann cells bind to collagen type V via syndecan-3-dependent binding to a novel high affinity heparin binding site in the alpha4(V)-NTD...
Fibronectin fibrillogenesis regulates three-dimensional neovessel formationXiaoming Zhou
The Division of Molecular Medicine and Genetics, Department of Internal Medicine, The Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, USA
Genes Dev 22:1231-43. 2008..These results advance a new model wherein Fn polymerization serves as a structural scaffolding that displays adhesive ligands on a mechanically ideal substratum for promoting neovessel development...
