Research Topics
| Steve ShoptawSummaryAffiliation: Friends Research Institute Country: USA Publications
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Publications
A random-effects Markov transition model for Poisson-distributed repeated measures with non-ignorable missing valuesJinhui Li
UCLA Department of Statistics, PO Box 951554, Los Angeles, CA 90095 1554, USA
Stat Med 26:2519-32. 2007..The method is demonstrated using both simulated data sets and a practical data set from a smoking cessation clinical trial...
Smoking cessation in methadone maintenanceSteve Shoptaw
Friends Research Institute, Los Angeles, CA, UCLA, Department of Psychiatry, Los Angeles, CA 90025, USA
Addiction 97:1317-28; discussion 1325. 2002..To evaluate relapse prevention (relapse prevention) and contingency management (contingency management) for optimizing smoking cessation outcomes using nicotine replacement therapy for methadone-maintained tobacco smokers...
Randomized placebo-controlled trial of baclofen for cocaine dependence: preliminary effects for individuals with chronic patterns of cocaine useSteven Shoptaw
UCLA Integrated Substance Abuse Program, Los Angeles, Calif 90025, USA
J Clin Psychiatry 64:1440-8. 2003..This screening trial evaluated whether the GABAB agonist baclofen demonstrated sufficient clinical efficacy to recommend an adequately powered trial of the medication as a pharmacotherapy for cocaine dependence...
Participants receiving dehydroepiandrosterone during treatment for cocaine dependence show high rates of cocaine use in a placebo-controlled pilot studySteve Shoptaw
Friends Research Institute, Los Angeles, CA, USA
Exp Clin Psychopharmacol 12:126-35. 2004..No differences were detected between conditions for cocaine craving or adverse experiences. High levels of medication compliance were documented. Results argue against using high doses of DHEA as a pharmacotherapy for cocaine dependence...
Evaluation of the cardiovascular and subjective effects of rivastigmine in combination with methamphetamine in methamphetamine-dependent human volunteersRichard De La Garza
David Geffen School of Medicine, University of California, Los Angeles, CA, USA
Int J Neuropsychopharmacol 11:729-41. 2008..05). Taken together, the findings in the current report suggest that pharmacological manipulations that enhance brain ACh warrant continued investigation as potential treatments for Meth addiction...
HIV-associated medical, behavioral, and psychiatric characteristics of treatment-seeking, methamphetamine-dependent men who have sex with menJames A Peck
Friends Research Institute, Los Angeles, CA, USA
J Addict Dis 24:115-32. 2005....
Behavioral treatment approaches for methamphetamine dependence and HIV-related sexual risk behaviors among urban gay and bisexual menSteven Shoptaw
Friends Research Institute, Los Angeles, CA 90025, USA
Drug Alcohol Depend 78:125-34. 2005..This project evaluated the efficacy of four behavioral drug abuse treatments for reducing methamphetamine use and sexual risk behaviors among this population...
Bupropion hydrochloride versus placebo, in combination with cognitive behavioral therapy, for the treatment of cocaine abuse/dependenceSteve Shoptaw
S David Geffen School of Medicine at UCLA, Department of Family Medicine, 10880 Wilshire Boulevard, Suite 540, Los Angeles, CA 90095, USA
J Addict Dis 27:13-23. 2008..The failure to find an effect for bupropion relative to placebo, when combined with standard cognitive behavioral therapy, dampens enthusiasm for future development of bupropion as a cocaine pharmacotherapy...
Subjective and cardiovascular effects of cocaine during treatment with amantadine and baclofen in combinationErin Rotheram-Fuller
UCLA Department of Family Medicine, 10880 Wilshire Blvd Suite 1800, Los Angeles, CA 90024, USA
Psychiatry Res 152:205-10. 2007..Study findings support the safety of the amantadine-baclofen combination treatment for cocaine dependence...
Methamphetamine use and other club drug use differ in relation to HIV status and risk behavior among gay and bisexual menEllen T Rudy
Department of Public Health, Los Angeles County, STD Program, Los Angeles, California 90007, USA
Sex Transm Dis 36:693-5. 2009..Of 6435 participants, newly recognized HIV status (OR: 3.02 95% CI: 2.30, 3.99) was associated with methamphetamine use compared with nondrug users, an association not found among other club drug users...
Psychiatric and substance dependence comorbidities, sexually transmitted diseases, and risk behaviors among methamphetamine-dependent gay and bisexual men seeking outpatient drug abuse treatmentSteven Shoptaw
Friends Research Institute, Inc, Los Angeles, California, USA
J Psychoactive Drugs 35:161-8. 2003..Findings indicate that gay and bisexual men seeking outpatient treatment for methamphetamine dependence are likely to experience psychiatric comorbidity and to have high rates of infectious disease, including HIV, syphilis and gonorrhea...
Outcomes using two tailored behavioral treatments for substance abuse in urban gay and bisexual menSteven Shoptaw
Department of Family Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024, USA
J Subst Abuse Treat 35:285-93. 2008..Findings replicate prior work and indicate that GCBT produces reliable, significant, and sustained reductions in stimulant use and sexual risk behaviors, particularly in methamphetamine-abusing gay and bisexual men...
Patient characteristics, HIV serostatus, and risk behaviors among gay and bisexual males seeking treatment for methamphetamine abuse and dependence in Los AngelesSteven Shoptaw
Friends Research Institute, Inc, Los Angeles, CA 90025, USA
J Addict Dis 21:91-105. 2002..Findings provide information that may prove helpful in tailoring culturally relevant treatment and prevention messages...
Depression ratings, reported sexual risk behaviors, and methamphetamine use: latent growth curve models of positive change among gay and bisexual men in an outpatient treatment programAdi Jaffe
Department of Psychology, University of California, Los Angeles, CA, USA
Exp Clin Psychopharmacol 15:301-7. 2007..This suggests that some users who respond well to treatment may show improvement in these co-occurring problems without a need for more intensive targeted interventions...
Associations between methamphetamine use and HIV among men who have sex with men: a model for guiding public policySteven Shoptaw
Department of Family Medicine, University of California, 10880 Wilshire Blvd, Suite 1800, Los Angeles, CA 90024, USA
J Urban Health 83:1151-7. 2006....
Changes in the meaning of sexual risk behaviors among gay and bisexual male methamphetamine abusers before and after drug treatmentCathy J Reback
Friends Research Institute, Inc, Los Angeles, California, USA
AIDS Behav 8:87-98. 2004..This study further demonstrates the value of coupling quantitative with qualitative data in understanding the meanings behind reductions in high-risk behaviors...
Randomized, placebo-controlled trial of baclofen and gabapentin for the treatment of methamphetamine dependenceKeith G Heinzerling
Integrated Substance Abuse Programs, Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024, USA
Drug Alcohol Depend 85:177-84. 2006..Future studies evaluating the effectiveness of baclofen and other GABAergic agents for treatment of methamphetamine may be warranted...
Methamphetamine use trends among street-recruited gay and bisexual males, from 1999 to 2007Cathy J Reback
Friends Research Institute, Inc, 1419 N La Brea Avenue, Los Angeles, CA 90028, USA
J Urban Health 85:874-9. 2008..These data also indicate the need for ongoing methamphetamine abuse and HIV-prevention interventions in this particular high-risk population...
Methamphetamine use in urban gay and bisexual populationsSteven Shoptaw
Department of Family Medicine, University of California Los Angeles, Los Angeles, CA, USA
Top HIV Med 14:84-7. 2006..Behavioral therapies, notably the approach of contingency management, are being investigated for reducing methamphetamine use and risk behaviors in the urban gay population...
Sustained reductions in drug use and depression symptoms from treatment for drug abuse in methamphetamine-dependent gay and bisexual menJames A Peck
UCLA Integrated Substance Abuse Programs, 11075 Santa Monica Boulevard, Suite 200, Los Angeles, CA 90025, USA
J Urban Health 82:i100-8. 2005..Findings show that behavioral methamphetamine abuse treatment yields reductions in methamphetamine use and concomitant depressive symptom ratings that are sustained to 1 year after treatment entry...
Methamphetamine use and infectious disease-related behaviors in men who have sex with men: implications for interventionsSteven Shoptaw
UCLA Department of Family Medicine and Integrated Substance Abuse Programs, David Geffen School of Medicine, Los Angeles, USA
Addiction 102:130-5. 2007....
Management of methamphetamine abuse and dependenceWalter Ling
Integrated Substance Abuse Programs, David Geffen School of Medicine at UCLA, University of California Los Angeles, 11075 Santa Monica Boulevard, Suite 200, Los Angeles, CA 90025, USA
Curr Psychiatry Rep 8:345-54. 2006..Clinicians and researchers must interact to efficiently address the problems of methamphetamine dependence, a major drug problem in the United States and the world...
A screening trial of amantadine as a medication for cocaine dependenceSteve Shoptaw
Friends Research Institute, Inc, 11075 Santa Monica Blvd, Suite 350, Los Angeles, CA 90025, USA
Drug Alcohol Depend 66:217-24. 2002..There were no significant differences in frequency or severity of reported adverse events by treatment condition. These results provide moderate support for further study of amantadine for the treatment of cocaine dependence...
Profile of lifetime methamphetamine use among homeless adults in Los AngelesAdeline Nyamathi
University of California, Los Angeles, School of Nursing, Room 2 250, Factor Building, Los Angeles, CA 90095 1702, USA
Drug Alcohol Depend 92:277-81. 2008....
Bridging sexual boundaries: men who have sex with men and women in a street-based sample in Los AngelesPamina M Gorbach
Department of Epidemiology, UCLA School of Public Health, University of California Los Angeles, 10880 Wilshire Blvd, Los Angeles, CA 90095 7353, USA
J Urban Health 86:63-76. 2009....
Impaired performance in a test of decision-making by opiate-dependent tobacco smokersErin Rotheram-Fuller
Friends Research Institute Inc, Los Angeles, CA 90025, USA
Drug Alcohol Depend 73:79-86. 2004..The findings suggest that among opiate-dependent individuals, tobacco smoking may be a marker for a more severe form of substance abuse disorder, reflecting impaired decision-making, as modeled by GT...
Status of methamphetamine users 2-5 years after outpatient treatmentRichard A Rawson
Matrix Institute on Addictions, Los Angeles, CA 90025, USA
J Addict Dis 21:107-19. 2002..In general, the follow up status of the sample was much improved as compared to before treatment. However, headaches and depression were reported at a similar rate at follow up as had been reported at treatment admission...
Homonegativity, substance use, sexual risk behaviors, and HIV status in poor and ethnic men who have sex with men in Los AngelesSteven Shoptaw
David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
J Urban Health 86:77-92. 2009....
Randomized, double-blind, placebo-controlled trial of modafinil for the treatment of methamphetamine dependenceKeith G Heinzerling
Department of Family Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
Drug Alcohol Depend 109:20-9. 2010..To compare modafinil to placebo for reducing methamphetamine (MA) use, improving retention, and reducing depressive symptoms and MA cravings. Rates of adverse events and cigarette smoking with modafinil versus placebo were also compared...
A comparison of contingency management and cognitive-behavioral approaches during methadone maintenance treatment for cocaine dependenceRichard A Rawson
University of California, Los Angeles, Integrated Substance Abuse Programs, 11075 Santa Monica Blvd, Suite 200, Los Angeles, CA 90025, USA
Arch Gen Psychiatry 59:817-24. 2002..This study compared 2 psychosocial approaches for the treatment of cocaine dependence: contingency management (CM) and cognitive-behavioral therapy (CBT)...
Randomized, placebo-controlled trial of bupropion for the treatment of methamphetamine dependenceSteven Shoptaw
Department of Family Medicine, David Geffen School of Medicine at UCLA, 10880 Wilshire Boulevard, Suite 540, Los Angeles, CA 90095, USA
Drug Alcohol Depend 96:222-32. 2008..A secondary objective compared bupropion to placebo for reducing cigarette smoking among MA dependent participants...
A public health response to the methamphetamine epidemic: the implementation of contingency management to treat methamphetamine dependenceSteven Shoptaw
David Geffen School of Medicine at UCLA, Department of Family Medicine, Los Angeles, CA, USA
BMC Public Health 6:214. 2006....
A comparison of contingency management and cognitive-behavioral approaches for stimulant-dependent individualsRichard A Rawson
UCLA Integrated Substance Abuse Programs, Los Angeles, CA 90025, USA
Addiction 101:267-74. 2006..The present study sought to directly compare the effectiveness of (CM) and (CBT) alone and in combination in reducing stimulant use...
Randomized, placebo-controlled trial of sertraline and contingency management for the treatment of methamphetamine dependenceSteven Shoptaw
Center for Health Promotion and Disease Prevention, Department of Family Medicine, David Geffen School of Medicine at UCLA, 10880 Wilshire Blvd, Suite 1800, Los Angeles, CA 90024, USA
Drug Alcohol Depend 85:12-8. 2006..This project evaluated the efficacy of sertraline (50mg bid) and contingency management (CM) for the treatment of methamphetamine dependence...
Hepatitis C virus infection among methamphetamine-dependent individuals in outpatient treatmentRachel Gonzales
UCLA Integrated Substance Abuse Programs, Los Angeles, CA 90025 7535, USA
J Subst Abuse Treat 31:195-202. 2006..Findings suggest a need for targeted education and prevention efforts about hepatitis C among high-risk MA users, including HCV testing coupled with referrals to HCV treatments...
Alcohol use reduction program in methadone maintained individuals with hepatitis C virus infectionAdeline Nyamathi
University of California, Los Angeles, School of Nursing, Los Angeles, California, USA
J Addict Dis 27:27-33. 2008..The findings suggest that healthcare providers' strategies designed to boost motivation, combined with various types of support, may prove successful in alcohol reduction among methadone-maintained clients...
Poor response to sertraline in methamphetamine dependence is associated with sustained craving for methamphetamineTodd Zorick
Department of Psychiatry, Greater Los Angeles Veterans Administration Healthcare System, Los Angeles, CA 90073, USA
Drug Alcohol Depend 118:500-3. 2011..However, clinical trials of serotonergic agents for MA addiction have been unsuccessful...
A multi-center randomized trial of buprenorphine-naloxone versus clonidine for opioid detoxification: findings from the National Institute on Drug Abuse Clinical Trials NetworkWalter Ling
David Geffen School of Medicine, NPI Integrated Substance Abuse Programs, University of California, Los Angeles, CA 90025, USA
Addiction 100:1090-100. 2005....
Hepatitis C virus infection, substance use and mental illness among homeless youth: a reviewAdeline M Nyamathi
UCLA School of Nursing, UCLA, Los Angeles, CA 90095 1702, USA
AIDS 19:S34-40. 2005..In this paper, we review the implications of these conditions, discuss the unique challenges faced by homeless youth, and explore potential strategies for harm reduction and intervention in this vulnerable population...
Effects of a nurse-managed program on hepatitis A and B vaccine completion among homeless adultsAdeline Nyamathi
School of Nursing, University of California Los Angeles, Los Angeles, CA 90095 1702, USA
Nurs Res 58:13-22. 2009..Ability to complete an HBV vaccination series is complicated by the need to prioritize competing needs, such as addiction issues, safe places to sleep, and food, over health concerns...
Predicting adherence to treatment for methamphetamine dependence from neuropsychological and drug use variablesAndy C Dean
Department of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute, 760 Westwood Plaza, Box 951759, Los Angeles, CA 90095, USA
Drug Alcohol Depend 105:48-55. 2009..On the basis of these findings, we recommend that research groups seeking to identify new predictors of treatment outcome compare the predictors to methamphetamine usage variables to assure that unique predictive power is attained...
Structural-level factors affecting implementation of the methadone maintenance therapy program in ChinaChunqing Lin
Department of Epidemiology, School of Public Health, University of California at Los Angeles, Los Angeles, CA 90024, USA
J Subst Abuse Treat 38:119-27. 2010..Comprehensive services should be incorporated into the MMT program. Extended operating hours and incentives for compliant clients should be implemented...
Randomized controlled pilot trial of cabergoline, hydergine and levodopa/carbidopa: Los Angeles Cocaine Rapid Efficacy Screening Trial (CREST)Steven Shoptaw
UCLA Integrated Substance Abuse Programs, Los Angeles, CA 90025, USA
Addiction 100:78-90. 2005..5 mg per week (n = 15); and placebo three times daily (n = 15) as potential pharmacotherapies for cocaine dependence...
Assessing missing data assumptions in longitudinal studies: an example using a smoking cessation trialXiaowei Yang
BayesSoft Inc, 11075 Santa Monica Blud, Suite 200, Los Angeles, CA 90025, USA
Drug Alcohol Depend 77:213-25. 2005..A carbon monoxide longitudinal data set in a smoking cessation study is used for illustration...
Smoking-induced change in intrasynaptic dopamine concentration: effect of treatment for Tobacco DependenceArthur L Brody
Department of Psychiatry, UCLA, Los Angeles, CA 90095, USA
Psychiatry Res 183:218-24. 2010..These data indicate that smoking-induced DA release is dose-dependent, and is not significantly affected by reductions in daily smoking levels or treatment type...
Challenges in providing services in methadone maintenance therapy clinics in China: service providers' perceptionsChunqing Lin
School of Public Health, University of California at Los Angeles, Los Angeles, CA 90024, USA
Int J Drug Policy 21:173-8. 2010..As of the end of November, 2008, 558 MMT clinics had been established countrywide. The objective of this study was to elucidate the difficulties and challenges as perceived by service providers working in MMT clinics...
Correlates of hospitalization for alcohol-using methadone-maintained persons with physical health problemsAdeline Nyamathi
University of California, Los Angeles, CA, USA
West J Nurs Res 31:525-43. 2009..Identification of hospitalization risk factors among alcohol-abusing MMT clients is a first step to developing risk-reducing interventions designed to lower hospitalization rates in this population...
Correlates of alcohol use among methadone-maintained adultsAdeline Nyamathi
University of California, Los Angeles, School of Nursing, 2 250 Factor, Box 951702, Los Angeles, CA 90095 1702, USA
Drug Alcohol Depend 101:124-7. 2009..In addition, promoting attention to general physical and mental health problems within MMT programs may be beneficial in enhancing health outcomes of this population...
Response: getting tough with smokingLirio S Covey
Sci Pract Perspect 2:40-2. 2003
Markov transition models for binary repeated measures with ignorable and nonignorable missing values- Xiaowei Yang
Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, CA 95616, USA
Stat Methods Med Res 16:347-64. 2007..Markov transition models provide a novel reconceptualization of treatment outcomes, offering both intuitive statistical values and relevant clinical insights...
Recruiting drug-using men who have sex with men into behavioral interventions: a two-stage approachDavid E Kanouse
THE RAND CORPORATION, 1776 Main Street, Santa Monica, CA 90407 2138, USA
J Urban Health 82:i109-19. 2005....
Functional regression analysis using an F test for longitudinal data with large numbers of repeated measuresXiaowei Yang
Department of Public Health Sciences, Division of Biostatistics, University of California, Davis, CA 95616, USA
Stat Med 26:1552-66. 2007..A simulation study is also conducted under the condition of the smoking data to investigate the statistical power for the F test, Wilks' likelihood ratio test, and the linear mixed-effects model using AIC...
Correlates of "non-problematic" and "problematic" substance use among depressed adolescents in primary careRise B Goldstein
Department of Psychiatry and Behavioral Science, University of California at Los Angeles, USA
J Addict Dis 26:39-52. 2007....
Imputation-based strategies for clinical trial longitudinal data with nonignorable missing valuesXiaowei Yang
Division of Biostatistics, School of Medicine, University of California, Med Sci 1 C, Suite 200, Davis, CA 95616, USA
Stat Med 27:2826-49. 2008..For illustration, the strategies were applied to a data set with continuous repeated measures from a smoking cessation clinical trial...
