Research Topics
Species | D B ThomasSummaryAffiliation: Fred Hutchinson Cancer Research Center Country: USA Publications
Research Grants
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Publications
Alternatives to a national system of population-based state cancer registriesDavid B Thomas
Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Am J Public Health 92:1064-6. 2002....
Human papillomaviruses and cervical cancer in Bangkok. I. Risk factors for invasive cervical carcinomas with human papillomavirus types 16 and 18 DNAD B Thomas
Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Am J Epidemiol 153:723-31. 2001....- Human papillomaviruses and cervical cancer in Bangkok. II. Risk factors for in situ and invasive squamous cell cervical carcinomasD B Thomas
Program in Epidemlogy, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Am J Epidemiol 153:732-9. 2001..Two indices of socioeconomic status were associated with a reduced risk of only invasive disease, suggesting the existence of unknown protective factors that operate after intraepithelial lesions develop... - Human papillomaviruses and cervical cancer in Bangkok. III. The role of husbands and commercial sex workersD B Thomas
Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Am J Epidemiol 153:740-8. 2001..Commercial sex workers in Bangkok are reservoirs of oncogenic HPV, and cervical cancer in monogamous Thai women develops in part as a result of transmission of these viruses to them by their husbands from prostitutes... - Risk of subsequent breast cancer in relation to characteristics of screening mammograms from women less than 50 years of ageDavid B Thomas
Program in Epidemiology, The Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 11:565-71. 2002..Women <50 years of age with class 1 or 2 calcifications or mammographically dense breasts, or both, should receive high priority for further evaluation and regular breast cancer screening... - Randomized trial of breast self-examination in Shanghai: final resultsDavid B Thomas
Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
J Natl Cancer Inst 94:1445-57. 2002..This study was conducted to determine whether an intensive program of BSE instruction will reduce the number of women dying of breast cancer... - Dust and chemical exposures, and miscarriage risk among women textile workers in Shanghai, ChinaE Y Wong
Department of Environmental and Occupational Health Sciences, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98195 7234, USA
Occup Environ Med 66:161-8. 2009..To investigate possible associations between miscarriage and occupational exposures in the Shanghai textile industry... - Lung cancer and occupational exposures other than cotton dust and endotoxin among women textile workers in Shanghai, ChinaH Checkoway
Department of Environmental and Occupational Health Sciences, University of Washington, Box 357234, Seattle, WA 98195 7234, USA
Occup Environ Med 68:425-9. 2011.... - Occupational risk factors for pancreatic cancer among female textile workers in Shanghai, ChinaW Li
Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Occup Environ Med 63:788-93. 2006..To investigate whether occupational exposures to dusts and chemicals in the Shanghai textile industry are associated with risk of pancreatic cancer... - Occupational risk factors for nasopharyngeal cancer among female textile workers in Shanghai, ChinaW Li
Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Occup Environ Med 63:39-44. 2006..6-fold excess risk of NPC (95% CI 1.0 to 12.1). CONCLUSIONS: Occupational exposure to cotton dust, acids, and caustics, and work in dyeing and printing jobs in the textile industry may have increased risk of NPC in this cohort... - Lung cancer risk among female textile workers exposed to endotoxinGeorge Astrakianakis
Departments of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA
J Natl Cancer Inst 99:357-64. 2007..We examine the association between endotoxin exposure and lung cancer risk in a cohort of female textile workers... - Reproductive history, occupational exposures, and thyroid cancer risk among women textile workers in Shanghai, ChinaE Y Wong
Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA, USA
Int Arch Occup Environ Health 79:251-8. 2006..CONCLUSIONS: Despite statistically imprecise risk estimates, the findings suggest potential associations with some occupational chemical exposures in this cohort of textile workers... - Development of a cancer research study in the Shanghai textile industryJanice E Camp
Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington 98195, USA
Int J Occup Environ Health 9:347-56. 2003..This project is an example of the unique research opportunities to be found in China, and illustrates how these data sources may be lost due to ongoing changes in the Chinese economy... - Risks of biliary tract cancer and occupational exposures among Shanghai women textile workers: a case-cohort studyChin Kuo Chang
Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, Washington, USA
Am J Ind Med 49:690-8. 2006..Biliary tract cancer (BTC) is a relatively rare malignancy worldwide. Little is known about potential etiologic contributions of occupational exposures... - Breast cancer in relation to induced abortions in a cohort of Chinese womenZ Ye
Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, PO Box 19024, MP 474, Seattle, Washington, WA 98109 1024, USA
Br J Cancer 87:977-81. 2002..Although increases in risk were observed in such women, they were not statistically significant and could have been due to recall bias. Abortions as they have been performed in China are not an important cause of breast cancer... - Glutathione S-transferase M1 and P1 polymorphisms and risk of breast cancer and fibrocystic breast conditions in Chinese womenLori C Sakoda
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Department of Epidemiology, University of Washington, Mailstop M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
Breast Cancer Res Treat 109:143-55. 2008..The observed increased risk of breast cancer associated with joint carriage of the GSTM1 null genotype and GSTP1 105-Val allele needs confirmation in other studies... - Polymorphisms in steroid hormone biosynthesis genes and risk of breast cancer and fibrocystic breast conditions in Chinese womenLori C Sakoda
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 17:1066-73. 2008..Our findings support the possibility that common allelic variation at the CYP11A1 D15S520 locus alters breast cancer risk in Chinese women... - Risk factors for fibroadenoma in a cohort of female textile workers in Shanghai, ChinaZakia Coriaty Nelson
Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Am J Epidemiol 156:599-605. 2002..The practice of breast self-examination detects some fibroadenomas that would otherwise not be detected... - Colorectal cancer incidence among female textile workers in Shanghai, China: a case-cohort analysis of occupational exposuresA J De Roos
Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98109 1024, USA
Cancer Causes Control 16:1177-88. 2005..7; 95% CI: 0.5-0.9), and a trend of decreasing rectum cancer incidence was observed by category of cumulative quantitative cotton dust or endotoxin exposures, when exposures were lagged by 20 years... - Physical activity, physical exertion, and miscarriage risk in women textile workers in Shanghai, ChinaEva Y Wong
Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, Washington, USA
Am J Ind Med 53:497-505. 2010..Strenuous occupational physical activity and physical demands may be risk factors for adverse reproductive outcomes... - Occupational exposures and risks of liver cancer among Shanghai female textile workers--a case-cohort studyChin Kuo Chang
Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA, USA
Int J Epidemiol 35:361-9. 2006..We investigated associations of occupational exposures to dusts and chemicals in a cohort of female textile workers... - Cancer among women textile workers in Shanghai, China: overall incidence patterns, 1989-1998Karen J Wernli
Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA
Am J Ind Med 44:595-9. 2003..Further research on this cohort will examine associations between site-specific cancers and occupational exposures to dusts and chemicals... - BRCA1 and BRCA2 mutations in women from Shanghai ChinaNicola M Suter
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Cancer Epidemiol Biomarkers Prev 13:181-9. 2004..Most alterations observed appear unique to the Chinese population, suggesting a resource that will be useful for assessing risk among both Chinese women and United States women of Chinese descent... - Dietary and other risk factors in women having fibrocystic breast conditions with and without concurrent breast cancer: a nested case-control study in Shanghai, ChinaWenjin Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Int J Cancer 115:981-93. 2005.... - Modeling, estimation and validation of cotton dust and endotoxin exposures in Chinese textile operationsGeorge Astrakianakis
Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA
Ann Occup Hyg 50:573-82. 2006.... - Genetic variation in CYP19A1 and risk of breast cancer and fibrocystic breast conditions among women in Shanghai, ChinaChu Chen
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Mailstop M5 C800, P O Box 19024, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 17:3457-66. 2008..Our findings suggest that CYP19A1 variation may enhance breast cancer development in some women, but further confirmation is warranted... - Antiperspirant use and the risk of breast cancerDana K Mirick
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
J Natl Cancer Inst 94:1578-80. 2002..9 and P =.40; for deodorant, OR = 1.2 and P =.16). These findings do not support the hypothesis that antiperspirant use increases the risk for breast cancer... - Development of a job exposure matrix (JEM) for the textile industry in Shanghai, ChinaKaren J Wernli
Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
J Occup Environ Hyg 3:521-9. 2006..This JEM could be applicable for epidemiologic research in other textile industries... - Risk factors for progression of squamous cell cervical carcinoma in-situ to invasive cervical cancer: results of a multinational studyDavid B Thomas
Fred Hutchinson Cancer Research Center, Program in Epidemiology, Seattle, WA 98109, USA
Cancer Causes Control 13:683-90. 2002..Women with a history of this condition need not avoid use of steroid contraceptives... - Menstrual and reproductive factors in relation to risk of endometrial cancer in Chinese womenKaren J Wernli
Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Cancer Causes Control 17:949-55. 2006..50, 95% CI 0.23-1.07). This prospective study confirms findings from previous case-control studies relating menstrual, reproductive, and contraceptive factors and endometrial carcinoma... - Occupational exposures and breast cancer among women textile workers in ShanghaiRoberta M Ray
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Epidemiology 18:383-92. 2007..Breast cancer incidence rates have been increasing in China over the past 2 decades. Most studies have focused on reproductive, dietary, and genetic risk factors. Little is known about the contribution of occupational exposures... - Occupational risk factors for esophageal and stomach cancers among female textile workers in Shanghai, ChinaKaren J Wernli
Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Am J Epidemiol 163:717-25. 2006..01) and stomach cancer (p-trend < 0.001) when exposures were lagged 20 years. Endotoxin has not been previously reported to be a protective factor for either stomach cancer or esophageal cancer and therefore warrants further study... - Plasma isoflavones and fibrocystic breast conditions and breast cancer among women in Shanghai, ChinaJohanna W Lampe
Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Cancer Epidemiol Biomarkers Prev 16:2579-86. 2007..Soy isoflavone exposure may influence breast cancer risk, but little is known of its association with benign conditions... 
Occupational exposures and ovarian cancer in textile workersKaren J Wernli
Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Epidemiology 19:244-50. 2008..Occupational risk factors for ovarian cancer have been investigated only to a limited extent. We conducted a case-cohort study to examine associations between occupational exposures and ovarian cancer in the textile industry...- Insulin-like growth factor-I, insulin-like growth factor binding protein-3 and the risk of fibrocystic breast conditions among Chinese womenChu Chen
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Int J Cancer 118:2303-9. 2006..13 (1.50-6.53), 4.57 (2.22-9.39) and 6.30 (3.08-12.89), compared with the lowest fourth. Our results suggest that elevated levels of IGF-I may contribute to the development of FBC... - A case-control study of risk factors for fibrocystic breast conditions: Shanghai Nutrition and Breast Disease Study, China, 1995-2000Chunyuan Wu
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Am J Epidemiol 160:945-60. 2004..A diet rich in fruits and vegetables may reduce cellular proliferation in the mammary epithelium; this is one mechanism by which such a diet could reduce risk of breast cancer... - Occupational risk factors for endometrial cancer among textile workers in Shanghai, ChinaKaren J Wernli
Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, Washington 9810, USA
Am J Ind Med 51:673-9. 2008..A case-cohort study was conducted to investigate associations between occupational exposures and endometrial cancer nested within a large cohort of textile workers in Shanghai, China... - Frequency of soy food consumption and serum isoflavone concentrations among Chinese women in ShanghaiCara L Frankenfeld
Department of Epidemiology, University of Washington, Seattle, WA 98109, USA
Public Health Nutr 7:765-72. 2004..CONCLUSIONS: The results suggest that the FFQ provides a useful marker of soy food consumption and isoflavone exposure in this population... - Early detection of breast cancer in countries with limited resourcesBenjamin O Anderson
Department of Surgery, University of Washington, Seattle, Washington 98195, USA
Breast J 9:S51-9. 2003..There are tremendous differences among and within countries, and a program to promote early detection must be tailored to each country's unique situation... - Monthly injectable steroid contraceptives and cervical carcinomaD B Thomas
Fred Hutchinson Cancer Research Center, Seattle, WA 98104
Am J Epidemiol 130:237-47. 1989..The original finding was probably due to chance, but a causal interpretation cannot be confidently ruled out, and additional studies are warranted... - Breast cancer and specific types of combined oral contraceptives. The WHO Collaborative Study of Neoplasia and Steroid ContraceptivesD B Thomas
Fred Hutchinson Cancer Research Center, Seattle, WA 98104
Br J Cancer 65:108-13. 1992..This study provides no evidence that risk of breast cancer in users of oral contraceptives varies by the type of oestrogen or progestin consumed... - Biomarkers of dietary exposure are associated with lower risk of breast fibroadenomas in Chinese womenS Coosje Dijkstra
Public Health Sciences Division, Fred Hutchinson Research Center, Seattle, WA 98109, USA
J Nutr 140:1302-10. 2010..The inverse associations between plasma isoflavone concentrations and RBC EPA and DPA and fibroadenoma risk suggest that higher intakes of soy foods and fatty fish may lower the risk of fibroadenomas... - Modelling the effect of screening for cervical cancer on the populationRuth Etzioni
Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Lancet 364:224-6. 2004 - Induced abortions and the risk of all cancers combined and site-specific cancers in ShanghaiKarin A Rosenblatt
Department of Kinesiology and Community Health, University of Illinois at Urbana Champaign, 127 Huff Hall, Champaign, IL 61820, USA
Cancer Causes Control 17:1275-80. 2006..No convincing associations with other cancers were observed. Women who have induced abortions after a live birth are not at increased risk of cancer and induced abortions may reduce risk of cancer of the corpus uteri... - Extra-tumoral breast tissue in breast cancer patients: variations with steroid contraceptive useTone B Aaman Vamre
Institute of Medical Biology, University of Tromsø, Norway
Int J Cancer 118:2827-31. 2006..The increased prevalence of extra-tumoral ductal carcinoma in situ in breast cancer patients who started OC use at high age may possibly be explained by a longer preinvasive phase in these patients... - [Randomized trial of breast self-examination in 266,064 women in Shanghai]Dao Li Gao
Department of Epidemiology, Zhongshan Hospital, Fudan University, Shanghai 200052, China
Zhonghua Zhong Liu Za Zhi 27:350-4. 2005..A randomized trial of breast self-examination (BSE) program was carried out to evaluate whether the intensive BSE can reduce the death number of women from breast cancer... - Erythrocyte fatty acids and breast cancer risk: a case-control study in Shanghai, ChinaJackilen Shannon
Center for Research on Occupational and Environmental Toxicology, Oregon Health and Science University, Portland, OR, USA
Am J Clin Nutr 85:1090-7. 2007..The SI reflects the activity of several genes involved in lipid metabolism, including fatty acid synthase and steroyl coenzyme-A desaturase, that have been shown to be overexpressed in breast cancer... - Monthly injectable contraceptives and the risk of all cancers combined and site-specific cancers in ShanghaiKarin A Rosenblatt
Department of Kinesiology and Community Health, University of Illinois at Urbana Champaign, Champaign, IL 61820, USA
Contraception 76:40-4. 2007..The risk of 12 types of cancer in relation to use of monthly injectable contraceptives was assessed in a prospective study in Shanghai, China... - Dietary risk factors for invasive and in-situ cervical carcinomas in Bangkok, ThailandJackilen Shannon
Portland VA Research Foundation, Oregon 97201, USA
Cancer Causes Control 13:691-9. 2002..This study was conducted to evaluate the possible effects of specific dietary factors on cervical carcinogenesis... - Differential risk of remission and ESRD in childhood FSGSDebbie S Gipson
UNC Kidney Center, University of North Carolina, Chapel Hill, USA
Pediatr Nephrol 21:344-9. 2006..10, 95% CI 0.01-0.79, p =0.03). In summary, proteinuria remission status is a valid predictor of long-term renal survival in children with FSGS... - Molecular analysis of an immature ovarian teratoma with gliomatosis peritonei and recurrence suggests genetic independence of multiple tumorsD Hunter Best
Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
Int J Oncol 25:17-25. 2004....
Research Grants
- RANDOMIZED TRIAL OF BREAST SELF EXAMINATION IN SHANGHAIDavid Thomas; Fiscal Year: 2001..No further intervention activities are proposed. After 10 years of follow-up, over 2.6 million woman-years will have accrued, and this trial will have 80% power to detect a reduction in breast cancer mortality of 30%. ..
- RANDOMIZED TRIAL OF BREAST SELF EXAMINATION IN SHANGHAIDavid Thomas; Fiscal Year: 1993....
- RANDOMIZED TRIAL OF BREAST SELF EXAMINATION IN SHANGHAIDavid Thomas; Fiscal Year: 1991..This study could be classified as Phase 4 cancer control research in a defined population...
- DIET, CELL PROLIFERATION AND BREAST CANCER IN SHANGHAIDavid Thomas; Fiscal Year: 2001..Also unlike prior epidemiologic studies of diet and breast cancer, in the proposed investigation the primary end points are various indices of cell proliferation. ..