Research Topics
| R H ReederSummaryAffiliation: Fred Hutchinson Cancer Research Center Country: USA Publications
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Detail Information
Publications
Saccharomyces cerevisiae RNA polymerase I terminates transcription at the Reb1 terminator in vivoR H Reeder
Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Mol Cell Biol 19:7369-76. 1999..In vivo assay of mutants of the Reb1p terminator shows that this site operates in vivo by the same mechanism as has previously been delineated through in vitro studies...
TATA binding protein can stimulate core-directed transcription by yeast RNA polymerase IP Aprikian
Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Mol Cell Biol 20:5269-75. 2000..This dual function of TBP, serving as a critical member of a core promoter complex as well as a contact point for upstream activators, appears similar to the dual roles that TBP also plays in transcription by RNA polII...
New model for the yeast RNA polymerase I transcription cycleP Aprikian
Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Mol Cell Biol 21:4847-55. 2001..This model accounts for previous observations that rRNA synthesis may be controlled by regulating both promoter accessibility and polymerase activity...
A novel 66-kilodalton protein complexes with Rrn6, Rrn7, and TATA-binding protein to promote polymerase I transcription initiation in Saccharomyces cerevisiaeC W Lin
Basic Sciences Division, Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Mol Cell Biol 16:6436-43. 1996..This assay also verified the previously described strong association between Rrn6 and Rrn7, independent of the Rrn6 leucine repeat...
RNA polymerase I transcription factor Rrn3 is functionally conserved between yeast and humanB Moorefield
Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA
Proc Natl Acad Sci U S A 97:4724-9. 2000..Rrn3 is the first RNA polymerase I-specific transcription factor shown to be functionally conserved between yeast and mammals, suggesting that at least one mechanism that regulates ribosomal RNA synthesis is conserved among eukaryotes...
The release element of the yeast polymerase I transcription terminator can function independently of Reb1pS W Jeong
Hutchinson Cancer Research Center, Seattle, Washington 98104, USA
Mol Cell Biol 15:5929-36. 1995..We discuss possible mechanisms whereby this polI release element might function...
Terminating transcription in eukaryotes: lessons learned from RNA polymerase IR H Reeder
Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Trends Biochem Sci 22:473-7. 1997..This has resulted in a burst of information concerning pol I termination mechanisms, which this review will attempt to summarize...
The mechanism of transcription termination by RNA polymerase IR H Reeder
Fred Hutchinson Cancer Research Center, Basic Sciences Division, Seattle, Washington 98104
Mol Microbiol 12:11-5. 1994....
Regulation of RNA polymerase I transcription in yeast and vertebratesR H Reeder
Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Prog Nucleic Acid Res Mol Biol 62:293-327. 1999..This suggests that multiple signaling pathways may also be involved. The involvement of ribosomal genes and their transcripts in events such as mitosis, cancer, and aging is discussed...
