Martin Prlic

Summary

Affiliation: Fred Hutchinson Cancer Research Center
Country: USA

Publications

  1. pmc iNKTs foil fungi
    Martin Prlic
    Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Cell Host Microbe 10:421-2. 2011
  2. pmc Dissociating markers of senescence and protective ability in memory T cells
    Martin Prlic
    Department of Immunology and Howard Hughes Medical Institute, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 7:e32576. 2012
  3. pmc Cutting edge: β-catenin is dispensable for T cell effector differentiation, memory formation, and recall responses
    Martin Prlic
    Department of Immunology and Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA
    J Immunol 187:1542-6. 2011
  4. pmc Duration of the initial TCR stimulus controls the magnitude but not functionality of the CD8+ T cell response
    Martin Prlic
    Department of Immunology and Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA
    J Exp Med 203:2135-43. 2006
  5. pmc Rapid generation of a functional NK-cell compartment
    Martin Prlic
    Department of Immunology and Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195 7370, USA
    Blood 110:2024-6. 2007
  6. pmc Exploring regulatory mechanisms of CD8+ T cell contraction
    Martin Prlic
    Department of Immunology and Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195
    Proc Natl Acad Sci U S A 105:16689-94. 2008
  7. ncbi request reprint Requirements for CD8 T-cell priming, memory generation and maintenance
    Martin Prlic
    Department of Immunology and Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA
    Curr Opin Immunol 19:315-9. 2007
  8. pmc Bystander-activated memory CD8 T cells control early pathogen load in an innate-like, NKG2D-dependent manner
    Talyn Chu
    Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Cell Rep 3:701-8. 2013
  9. ncbi request reprint Immunology. An antibody paradox, resolved
    Martin Prlic
    Department of Immunology and the Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195 7370, USA
    Science 311:1875-6. 2006

Collaborators

Detail Information

Publications9

  1. pmc iNKTs foil fungi
    Martin Prlic
    Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Cell Host Microbe 10:421-2. 2011
    ....
  2. pmc Dissociating markers of senescence and protective ability in memory T cells
    Martin Prlic
    Department of Immunology and Howard Hughes Medical Institute, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 7:e32576. 2012
    ..However, we report here that these currently used biomarkers to measure senescence do not predict proliferative potential or protective ability, but merely reflect initial priming conditions...
  3. pmc Cutting edge: β-catenin is dispensable for T cell effector differentiation, memory formation, and recall responses
    Martin Prlic
    Department of Immunology and Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA
    J Immunol 187:1542-6. 2011
    ..Together, our data suggest that self-renewal and differentiation are regulated differently in memory T cells compared with epithelial and hematopoietic stem cells...
  4. pmc Duration of the initial TCR stimulus controls the magnitude but not functionality of the CD8+ T cell response
    Martin Prlic
    Department of Immunology and Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA
    J Exp Med 203:2135-43. 2006
    ..These results indicate that the duration of initial antigen encounter influences the magnitude of the primary response, but does not program responsiveness during the secondary challenge...
  5. pmc Rapid generation of a functional NK-cell compartment
    Martin Prlic
    Department of Immunology and Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195 7370, USA
    Blood 110:2024-6. 2007
    ..Finally, we show that NK cells rapidly generated by IL-2 complexes kill MHC class I-deficient cells effectively in vivo. These data underline the unique therapeutic potential of IL-2 complexes...
  6. pmc Exploring regulatory mechanisms of CD8+ T cell contraction
    Martin Prlic
    Department of Immunology and Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195
    Proc Natl Acad Sci U S A 105:16689-94. 2008
    ..We propose that the fate of a CD8 effector cell is predetermined before the onset of contraction and discuss possible mechanisms of regulation...
  7. ncbi request reprint Requirements for CD8 T-cell priming, memory generation and maintenance
    Martin Prlic
    Department of Immunology and Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA
    Curr Opin Immunol 19:315-9. 2007
    ..Recent advances shed light on the relative roles of TCR signals and environmental cues in guiding the development of CD8(+) effector T cells into CD8(+) memory T cells and supporting CD8(+) memory T-cell maintenance...
  8. pmc Bystander-activated memory CD8 T cells control early pathogen load in an innate-like, NKG2D-dependent manner
    Talyn Chu
    Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Cell Rep 3:701-8. 2013
    ..Together, these data suggest an innate role for memory CD8 T cells in the early immune response before the onset of a de novo generated, antigen-specific CD8 T cell response...
  9. ncbi request reprint Immunology. An antibody paradox, resolved
    Martin Prlic
    Department of Immunology and the Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195 7370, USA
    Science 311:1875-6. 2006