Research Topics
Genomes and GenesSpecies | E PetersdorfSummaryAffiliation: Fred Hutchinson Cancer Research Center Country: USA Publications
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Publications
Clinical significance of donor-recipient HLA matching on survival after myeloablative hematopoietic cell transplantation from unrelated donorsE W Petersdorf
Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA98109, USA
Tissue Antigens 69:25-30. 2007..The permissibility of a given HLA mismatch is in part defined by the locus and by disease risk...- 14thInternational HLA and Immunogenetics Workshop: report on hematopoietic cell transplantationE Petersdorf
Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Tissue Antigens 69:17-24. 2007.... - HLA matching in hematopoietic cell transplantationE M Mickelson
Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Hum Immunol 61:92-100. 2000..The use of these methods to optimize donor selection will improve both donor identification and the success of unrelated donor transplants... - Hematopoietic stem cell transplants from unrelated donorsJ A Hansen
Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Immunol Rev 157:141-51. 1997..In order to provide transplants for all patients, improved methods for GVHD prophylaxis are needed that will make it possible to safely perform transplants even across limited degrees of HLA disparity... - The role of HLA matching in hematopoietic cell transplantationJ A Hansen
Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Rev Immunogenet 1:359-73. 1999..There remain, however, important unanswered questions about the relative importance of different HLA loci in matching strategies, as well as incomplete information about permissible limits of mismatching in different patient populations... - Genomics of unrelated-donor hematopoietic cell transplantationE Petersdorf
University of Washington, School of Medicine, 1959 NE Pacific Street, Seattle, Washington 98105, USA
Curr Opin Immunol 13:582-9. 2001..Delineation of the function of these markers as transplantation determinants may provide alternative means for optimizing the results of hematopoietic cell transplantation... - MHC microsatellite diversity and linkage disequilibrium among common HLA-A, HLA-B, DRB1 haplotypes: implications for unrelated donor hematopoietic transplantation and disease association studiesM Malkki
The Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Tissue Antigens 66:114-24. 2005..Markers with high HSH values will be most informative in studies investigating MHC region disease-susceptibility genes where HLA haplotypic effects are known to exist... - Immune response gene polymorphisms in unrelated donor hematopoietic cell transplantationM Malkki
Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Tissue Antigens 69:50-3. 2007..The International Histocompatibility Working Group (IHWG) in hematopoietic cell transplantation took a candidate gene approach to define the risks associated with genetic variation for a panel of well-characterized IRG... - Effect of HLA-A2 allele disparity on clinical outcome in hematopoietic cell transplantation from unrelated donorsY Morishima
Aichi Cancer Center, Nagoya, Japan
Tissue Antigens 69:31-5. 2007.... - Clinical importance of HLA-DPB1 in haematopoietic cell transplantationB E Shaw
Department of Haematology, Nottingham City Hospital, Nottingham, UK
Tissue Antigens 69:36-41. 2007..33; P-value = <0.0001], while protecting against disease relapse (HR: 0.82, P-value = 0.01). These data support an immunogenic role for HLA-DPB1 in HCT and the need for pretransplant tissue typing at this locus... - Hematopoietic stem cell transplantation: killer immunoglobulin-like receptor componentK C Hsu
Adult Allogeneic Blood and Marrow Transplantation Service, Memorial Hospital, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Tissue Antigens 69:42-5. 2007..KIR genotyping for unrelated donors and recipients will clarify the role of these receptors in transplant outcome... - MHC class I, II, and III microsatellite marker matching and survival in unrelated donor hematopoietic cell transplantationM Malkki
Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Tissue Antigens 69:46-9. 2007..Retrospective analysis of human leukocyte antigen-identical unrelated donor transplants provided a homogeneous population to measure Msat-associated risks of mortality... - Tissue typing in support of unrelated hematopoietic cell transplantationE W Petersdorf
Division of Clinical Research, Fred Hutchinson Cancer Research Ctr, Division of Clinical Research, and Department of Medicine, University of Washington, Seattle 98109 1024, USA
Tissue Antigens 61:1-11. 2003.... - Busulfan concentration and graft rejection in pediatric patients undergoing hematopoietic stem cell transplantationJ S McCune
Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Bone Marrow Transplant 30:167-73. 2002..It may be possible to improve the outcome of HSCT in pediatric patients receiving the BU/CY regimen through optimization of busulfan C(SS) and better definition of the contribution of activated cyclophosphamide metabolites to toxicity... - Identification of a novel HLA-B*07 allele--HLA-B*0726B Herbut
Tissue Typing Laboratory, Calgary Laboratory Services, Foothills Medical Centre, Calgary, Canada
Tissue Antigens 59:60-2. 2002..This results in an amino acid substitution from arginine to leucine at residue 156 in exon 3... - Seven new DPB1 alleles and their population distributionP V Moonsamy
Department of Human Genetics, Roche Molecular Systems, Alameda, CA
Tissue Antigens 43:249-52. 1994 - Population study of allelic diversity in the human MHC class I-related MIC-A geneE W Petersdorf
Fred Hutchinson Cancer Research Center, 1100 Fairview Ave North, Seattle, WA 98109 1024, USA
Immunogenetics 49:605-12. 1999..These results confirm and extend previous knowledge on the polymorphism of MIC-A. The strong positive linkage of certain MIC-A and HLA-B alleles may have implications for studies related to MHC-associated diseases and transplantation... - The biological significance of HLA-DP gene variation in haematopoietic cell transplantationE W Petersdorf
Division of Clinical Research, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, D4 100, Seattle, WA 98109 1024, USA
Br J Haematol 112:988-94. 2001..1; P = 0.01). HLA-DP plays an important role in the alloimmune response. A threshold effect of multiple HLA-DP disparities is evident in determining the risk of acute GVHD after haematopoietic cell transplantation from unrelated donors... - Generation of HLA-C-specific cytotoxic T cells in association with marrow graft rejection: analysis of alloimmunity by T-cell cloning and testing of T-cell-receptor rearrangementsJ Pei
Fred Hutchinson Cancer Research Center and the Department of Medicine, University of Washington, Seattle 98109-1024, USA
Biol Blood Marrow Transplant 7:378-83. 2001.... - Effect of HLA class II gene disparity on clinical outcome in unrelated donor hematopoietic cell transplantation for chronic myeloid leukemia: the US National Marrow Donor Program ExperienceE W Petersdorf
Fred Hutchinson Cancer Research Center, the U.S. National Marrow Donor Program, Georgetown University, Memorial Sloan Kettering Cancer Center, USA
Blood 98:2922-9. 2001..Furthermore, a good-risk population of patients whose transplantations were performed in the first CP of disease from HLA-A, B, DRB1 matched unrelated donors can be shown to have superior survival... - Nomenclature for factors of the HLA system, 2004S G E Marsh
Tissue Antigens 65:301-69. 2005 - Nomenclature for factors of the HLA system, 1998J G Bodmer
ICRF Cancer and Immunogenetics Laboratory, Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford, United Kingdom
Tissue Antigens 53:407-46. 1999 - Nomenclature for factors of the HLA system, 2004S G E Marsh
Int J Immunogenet 32:107-59. 2005 - Unique sequences for two HLA-DRB1 genes expressed on distinct DRw6 haplotypesE W Petersdorf
Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington 98104
Immunogenetics 32:96-103. 1990.... - HLA-DRB1 first domain sequence for a novel DR4 allele designated DRB1*0413E W Petersdorf
Fred Hutchinson Cancer Research Center, Seattle, Washington
Tissue Antigens 40:267-8. 1992..DRB1*0413 is a DRB1*0401-variant differing from DRB1*0401 only at codon 86 where valine is present instead of glycine...