E R Nemecek

Summary

Affiliation: Fred Hutchinson Cancer Research Center
Country: USA

Publications

  1. ncbi Antibody-based therapy of human leukemia
    Eneida R Nemecek
    Pediatric Hematology Oncology Fellow, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Curr Opin Hematol 9:316-21. 2002
  2. ncbi Treatment of neuroblastoma in patients with neurocristopathy syndromes
    Eneida R Nemecek
    Pediatric Hematology Oncology, Fred Hutchinson Cancer Research Center, University of Washington, Seattle 98109, USA
    J Pediatr Hematol Oncol 25:159-62. 2003
  3. ncbi Use of radiolabeled antibodies in the treatment of childhood acute leukemia
    Eneida R Nemecek
    Divisions of Clinical Research and Pediatric Hematology Oncology, Fred Hutchinson Cancer Research Center and University of Washington, PO Box 19024, Seattle, WA 98109 1024, USA
    Pediatr Transplant 7:89-94. 2003
  4. ncbi Outcome of allogeneic bone marrow transplantation for children with advanced acute myeloid leukemia
    E R Nemecek
    Department of Pediatrics, Clinical Research Division, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109, USA
    Bone Marrow Transplant 34:799-806. 2004
  5. ncbi Biodistribution of yttrium-90-labeled anti-CD45 antibody in a nonhuman primate model
    Eneida R Nemecek
    Division of Clinical Research, Fred Hutchinson Cancer Research Center, University of Washington, 1100 Fairview Avenue North, Seattle, WA 98109, USA
    Clin Cancer Res 11:787-94. 2005
  6. ncbi Pretargeting CD45 enhances the selective delivery of radiation to hematolymphoid tissues in nonhuman primates
    Damian J Green
    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Blood 114:1226-35. 2009
  7. ncbi A prospective study of G-CSF primed bone marrow as a stem-cell source for allogeneic bone marrow transplantation in children: a Pediatric Blood and Marrow Transplant Consortium (PBMTC) study
    Haydar Frangoul
    Department of Pediatrics, Vanderbilt University, Nashville, TN 37232 2573, USA
    Blood 110:4584-7. 2007
  8. ncbi Extracorporeal adsorption therapy: a method to improve targeted radiation delivered by radiometal-labeled monoclonal antibodies
    Eneida R Nemecek
    Department of Pediatrics, Oregon Health and Science University, Portland, OR, USA
    Cancer Biother Radiopharm 23:181-91. 2008

Research Grants

  1. Radioimmunotherapy of Acute Leukemia
    Eneida Nemecek; Fiscal Year: 2007

Detail Information

Publications8

  1. ncbi Antibody-based therapy of human leukemia
    Eneida R Nemecek
    Pediatric Hematology Oncology Fellow, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Curr Opin Hematol 9:316-21. 2002
    ..Antibodies reactive with CD52 and CD20 antigens have been studied for the management of B-cell leukemia. This article reviews the most current clinical trials using monoclonal antibodies in the management of leukemia...
  2. ncbi Treatment of neuroblastoma in patients with neurocristopathy syndromes
    Eneida R Nemecek
    Pediatric Hematology Oncology, Fred Hutchinson Cancer Research Center, University of Washington, Seattle 98109, USA
    J Pediatr Hematol Oncol 25:159-62. 2003
    ..They represent two of only three long-term disease-free survivors of neurocristopathy-associated neuroblastoma reported in the literature...
  3. ncbi Use of radiolabeled antibodies in the treatment of childhood acute leukemia
    Eneida R Nemecek
    Divisions of Clinical Research and Pediatric Hematology Oncology, Fred Hutchinson Cancer Research Center and University of Washington, PO Box 19024, Seattle, WA 98109 1024, USA
    Pediatr Transplant 7:89-94. 2003
    ..This paper will review the rationale for using this approach, our current experience with radiolabeled anti-CD45 antibody, and the potential challenges encountered in treating children with radiolabeled antibodies...
  4. ncbi Outcome of allogeneic bone marrow transplantation for children with advanced acute myeloid leukemia
    E R Nemecek
    Department of Pediatrics, Clinical Research Division, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109, USA
    Bone Marrow Transplant 34:799-806. 2004
    ..Survival for children transplanted in CR2 or untreated first relapse is higher than that previously reported, but relapse remains the major cause of treatment failure regardless of disease stage...
  5. ncbi Biodistribution of yttrium-90-labeled anti-CD45 antibody in a nonhuman primate model
    Eneida R Nemecek
    Division of Clinical Research, Fred Hutchinson Cancer Research Center, University of Washington, 1100 Fairview Avenue North, Seattle, WA 98109, USA
    Clin Cancer Res 11:787-94. 2005
    ..We evaluated the organ localization of yttrium-90-labeled anti-CD45 ((90)Y-anti-CD45) antibody in macaques, a model that had previously predicted iodine-131-labeled anti-CD45 ((131)I-anti-CD45) antibody biodistribution in humans...
  6. ncbi Pretargeting CD45 enhances the selective delivery of radiation to hematolymphoid tissues in nonhuman primates
    Damian J Green
    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Blood 114:1226-35. 2009
    ..These results support proceeding to anti-CD45 PRIT clinical trials for patients with both leukemia and lymphoma...
  7. ncbi A prospective study of G-CSF primed bone marrow as a stem-cell source for allogeneic bone marrow transplantation in children: a Pediatric Blood and Marrow Transplant Consortium (PBMTC) study
    Haydar Frangoul
    Department of Pediatrics, Vanderbilt University, Nashville, TN 37232 2573, USA
    Blood 110:4584-7. 2007
    ..Collection of G-BM from pediatric donors is safe, and can result in high NC and CD34 cell doses that facilitate engraftment after myeloablative BMT without a discernable increase in the risk of GVHD...
  8. ncbi Extracorporeal adsorption therapy: a method to improve targeted radiation delivered by radiometal-labeled monoclonal antibodies
    Eneida R Nemecek
    Department of Pediatrics, Oregon Health and Science University, Portland, OR, USA
    Cancer Biother Radiopharm 23:181-91. 2008
    ..We examined an "extracorporeal adsorption therapy" (ECAT) method to remove circulating unbound radioimmunoconjugate and improve the ratios of radiation delivered to B-cells in a macaque model...

Research Grants1

  1. Radioimmunotherapy of Acute Leukemia
    Eneida Nemecek; Fiscal Year: 2007
    ....