Christopher Li

Summary

Affiliation: Fred Hutchinson Cancer Research Center
Country: USA

Publications

  1. ncbi request reprint Use of menopausal hormone therapy and risk of ductal and lobular breast cancer among women 55-74 years of age
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Breast Cancer Res Treat 145:481-9. 2014
  2. pmc Reproductive factors and risk of estrogen receptor positive, triple-negative, and HER2-neu overexpressing breast cancer among women 20-44 years of age
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M4 C 308, P O Box 19024, Seattle, WA 98109 1024, USA
    Breast Cancer Res Treat 137:579-87. 2013
  3. pmc Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Breast Cancer Res Treat 135:611-8. 2012
  4. pmc Effect of depo-medroxyprogesterone acetate on breast cancer risk among women 20 to 44 years of age
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Cancer Res 72:2028-35. 2012
  5. pmc Hormone receptor status, tumor characteristics, and prognosis: a prospective cohort of breast cancer patients
    Lisa K Dunnwald
    Department of Epidemiology, University of Washington, Box 356113, 1959 NE Pacific St, Seattle, WA 98195, USA
    Breast Cancer Res 9:R6. 2007
  6. ncbi request reprint Risk of invasive breast carcinoma among women diagnosed with ductal carcinoma in situ and lobular carcinoma in situ, 1988-2001
    Christopher I Li
    Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Epidemiology Program, Seattle, Washington, USA
    Cancer 106:2104-12. 2006
  7. ncbi request reprint Interactions between body mass index and hormone therapy and postmenopausal breast cancer risk (United States)
    Christopher I Li
    Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, 1100 Fairview Avenue North, M4 C308, 19024, Seattle, Washington 98109 1024, USA
    Cancer Causes Control 17:695-703. 2006
  8. ncbi request reprint Relationship between established breast cancer risk factors and risk of seven different histologic types of invasive breast cancer
    Christopher I Li
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 15:946-54. 2006
  9. pmc Discovery and validation of breast cancer early detection biomarkers in preclinical samples
    Christopher I Li
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Horm Cancer 2:125-31. 2011
  10. pmc Relationship between radiation exposure and risk of second primary cancers among atomic bomb survivors
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Departments of Epidemiology and Biostatistics, University of Washington, Seattle, WA 98109 1024, USA
    Cancer Res 70:7187-98. 2010

Detail Information

Publications72

  1. ncbi request reprint Use of menopausal hormone therapy and risk of ductal and lobular breast cancer among women 55-74 years of age
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Breast Cancer Res Treat 145:481-9. 2014
    ....
  2. pmc Reproductive factors and risk of estrogen receptor positive, triple-negative, and HER2-neu overexpressing breast cancer among women 20-44 years of age
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M4 C 308, P O Box 19024, Seattle, WA 98109 1024, USA
    Breast Cancer Res Treat 137:579-87. 2013
    ..Further studies clarifying the biological mechanisms underlying this relationship and confirming our results with respect to age at first birth and the interval between age at menarche and age at first birth are needed...
  3. pmc Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Breast Cancer Res Treat 135:611-8. 2012
    ..Further research is required to followup on promising candidates in larger sample sizes and to better understand their potential biologic importance as our understanding of the etiology of triple-negative breast cancer continues to grow...
  4. pmc Effect of depo-medroxyprogesterone acetate on breast cancer risk among women 20 to 44 years of age
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Cancer Res 72:2028-35. 2012
    ....
  5. pmc Hormone receptor status, tumor characteristics, and prognosis: a prospective cohort of breast cancer patients
    Lisa K Dunnwald
    Department of Epidemiology, University of Washington, Box 356113, 1959 NE Pacific St, Seattle, WA 98195, USA
    Breast Cancer Res 9:R6. 2007
    ..However, few studies have evaluated variations in the risks of breast cancer-specific mortality across ER/PR status by either demographic or clinical characteristics...
  6. ncbi request reprint Risk of invasive breast carcinoma among women diagnosed with ductal carcinoma in situ and lobular carcinoma in situ, 1988-2001
    Christopher I Li
    Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Epidemiology Program, Seattle, Washington, USA
    Cancer 106:2104-12. 2006
    ..Incidence rates of ductal carcinoma in situ (DCIS) and lobular carcinoma in situ (LCIS) have been rising, but little is known about which patients will develop invasive breast cancer or what types of tumors these patients may develop...
  7. ncbi request reprint Interactions between body mass index and hormone therapy and postmenopausal breast cancer risk (United States)
    Christopher I Li
    Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, 1100 Fairview Avenue North, M4 C308, 19024, Seattle, Washington 98109 1024, USA
    Cancer Causes Control 17:695-703. 2006
    ..To assess interactions between use of estrogen plus progestin hormone therapy (EPHT) and body mass index (BMI) in relation to risks of different types of breast cancer, based on histology and hormone receptor status...
  8. ncbi request reprint Relationship between established breast cancer risk factors and risk of seven different histologic types of invasive breast cancer
    Christopher I Li
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 15:946-54. 2006
    ....
  9. pmc Discovery and validation of breast cancer early detection biomarkers in preclinical samples
    Christopher I Li
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Horm Cancer 2:125-31. 2011
    ....
  10. pmc Relationship between radiation exposure and risk of second primary cancers among atomic bomb survivors
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Departments of Epidemiology and Biostatistics, University of Washington, Seattle, WA 98109 1024, USA
    Cancer Res 70:7187-98. 2010
    ..Radiation is a potent carcinogen and those with substantial exposures who are diagnosed with a first primary cancer should be carefully screened for second primary cancers, particularly for cancers that are radiation-sensitive...
  11. pmc Alcohol consumption and risk of postmenopausal breast cancer by subtype: the women's health initiative observational study
    Christopher I Li
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Natl Cancer Inst 102:1422-31. 2010
    ..This association is thought to be largely hormonally driven, so alcohol use may be more strongly associated with hormonally sensitive breast cancers. Few studies have evaluated how alcohol-related risk varies by breast cancer subtype...
  12. pmc Relationship between migraine history and breast cancer risk among premenopausal and postmenopausal women
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 18:2030-4. 2009
    ..It extends the prior report in observing that this relationship holds for both premenopausal and postmenopausal women and is independent of exposure to common migraine triggers...
  13. pmc Adjuvant hormonal therapy for breast cancer and risk of hormone receptor-specific subtypes of contralateral breast cancer
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Cancer Res 69:6865-70. 2009
    ..This is of clinical concern given the poorer prognosis of ER- compared with ER+ tumors...
  14. pmc Relationship between potentially modifiable lifestyle factors and risk of second primary contralateral breast cancer among women diagnosed with estrogen receptor-positive invasive breast cancer
    Christopher I Li
    Divisions of Public Health Sciences and Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Clin Oncol 27:5312-8. 2009
    ..We evaluated the relationships between obesity, alcohol consumption, and smoking on risk of second primary invasive contralateral breast cancer among breast cancer survivors...
  15. doi request reprint Relationship between menopausal hormone therapy and risk of ductal, lobular, and ductal-lobular breast carcinomas
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 17:43-50. 2008
    ..Further studies focusing on the etiology of lobular carcinomas are needed...
  16. pmc Migraine history and breast cancer risk among postmenopausal women
    Christopher I Li
    Fred Hutchinson Cancer Research Center, 1100 N Fairview Ave, M4 C308, Seattle, WA 98109 1024, USA
    J Clin Oncol 28:1005-10. 2010
    ..06). CONCLUSION This study supports the hypothesis that a history of migraine is associated with a lower risk of breast cancer and that this relationship is independent of recent NSAID use...
  17. ncbi request reprint Changes in breast cancer incidence rates in the United States by histologic subtype and race/ethnicity, 1995 to 2004
    Christopher I Li
    Division of Public Health Science, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 16:2773-80. 2007
    ..The declines observed thus far are likely attributable to saturation of screening, although further declines related to the widespread cessation of hormone use may follow...
  18. pmc Timing of menarche and first full-term birth in relation to breast cancer risk
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Am J Epidemiol 167:230-9. 2008
    ..The authors conclude that the interval between age at menarche and age at first birth is associated with the risk of hormonally sensitive types of breast cancer, particularly among White women...
  19. ncbi request reprint Relationship between age maximum height is attained, age at menarche, and age at first full-term birth and breast cancer risk
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 16:2144-9. 2007
    ....
  20. pmc Relationship between diabetes and risk of second primary contralateral breast cancer
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109 1024, USA
    Breast Cancer Res Treat 125:545-51. 2011
    ..This is the first study to report this relationship, but if confirmed efforts to insure that diabetic breast cancer survivors are carefully screened for second breast cancers may be warranted...
  21. pmc Clinical characteristics of different histologic types of breast cancer
    C I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M4 C308, PO Box 19024, Seattle, WA 98109 1024, USA
    Br J Cancer 93:1046-52. 2005
    ..The histologic types of breast cancer studied here differ greatly in their clinical presentations, and the differences in their hormone receptor profiles and grades point to their likely different aetiologies...
  22. ncbi request reprint The relationship between various measures of cigarette smoking and risk of breast cancer among older women 65-79 years of age (United States)
    Christopher I Li
    Division of Public Health Sciences, Epidemiology Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Cancer Causes Control 16:975-85. 2005
    ..A further understanding of the timing of smoking, and its interaction with other factors, may enhance our knowledge of whether and by what mechanisms smoking alters breast cancer risk...
  23. doi request reprint Risk of mortality by histologic type of breast cancer in the United States
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Horm Cancer 1:156-65. 2010
    ..Though many of these histologic subtypes are quite rare, consideration of the mortality risk associated with a given subtype may be clinically useful when making decisions regarding treatment and follow-up...
  24. ncbi request reprint Tamoxifen therapy for primary breast cancer and risk of contralateral breast cancer
    C I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Natl Cancer Inst 93:1008-13. 2001
    ..Tamoxifen therapy reduces this risk, but it is unclear if this benefit exists for both estrogen receptor (ER)-positive and ER-negative contralateral tumors...
  25. ncbi request reprint Differences in breast cancer hormone receptor status and histology by race and ethnicity among women 50 years of age and older
    Christopher I Li
    Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, Washington 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 11:601-7. 2002
    ..Understanding the factors underlying these differences may provide further insight into breast cancer etiology in different populations...
  26. ncbi request reprint Changing incidence of lobular carcinoma in situ of the breast
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Breast Cancer Res Treat 75:259-68. 2002
    ..48/100,000 person-years). LCIS incidence rates have steadily increased from 1978 to 1998 only among postmenopausal women. Further research is required to assess what factors are contributing to these trends...
  27. ncbi request reprint Incidence of invasive breast cancer by hormone receptor status from 1992 to 1998
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Clin Oncol 21:28-34. 2003
    ..This is because hormone receptor status may reflect different etiologic pathways and is useful in predicting response to adjuvant therapy and prognosis...
  28. ncbi request reprint Differences in breast cancer stage, treatment, and survival by race and ethnicity
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, MP 381, PO Box 19024, Seattle, WA 98109 1024, USA
    Arch Intern Med 163:49-56. 2003
    ..However, Asians and Pacific Islanders and Hispanic whites are heterogeneous populations, and few studies have evaluated breast cancer stage, treatments, and mortality rates for subgroups of these populations...
  29. ncbi request reprint Trends in incidence rates of invasive lobular and ductal breast carcinoma
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, MP 381, PO Box 19024, Seattle, Wash 98109 1024, USA
    JAMA 289:1421-4. 2003
    ..Lobular carcinoma is less common than ductal carcinoma but can be more difficult to diagnose because of its subtle elusive infiltrative pattern...
  30. ncbi request reprint Birthweight and risk of overall and cause-specific childhood mortality
    Christopher I Li
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Paediatr Perinat Epidemiol 17:164-70. 2003
    ..Our results suggest that birthweight exerts important influences on children's risk of age-specific and cause-specific mortalities, particularly those with a strong biological component...
  31. ncbi request reprint Relationship between long durations and different regimens of hormone therapy and risk of breast cancer
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    JAMA 289:3254-63. 2003
    ..Women using combined estrogen and progestin hormone replacement therapy (CHRT) have an increased risk of breast cancer; however, data on use for long durations and on risk associated with patterns of use are lacking...
  32. pmc Epidemiologic and molecular risk factors for contralateral breast cancer among young women
    C I Li
    Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, 1100 Fairview Avenue North, MP 381, PO Box 19024, Seattle, WA 98109 1024, USA
    Br J Cancer 89:513-8. 2003
    ..Further observational studies are needed to confirm these findings and to evaluate whether testing for c-erbB-2 in this population may help identify those at high risk for CBC...
  33. ncbi request reprint Relation between use of antihypertensive medications and risk of breast carcinoma among women ages 65-79 years
    Christopher I Li
    Public Health Sciences Division, Epidemiology Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Cancer 98:1504-13. 2003
    ....
  34. ncbi request reprint Age-specific incidence rates of in situ breast carcinomas by histologic type, 1980 to 2001
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 14:1008-11. 2005
    ..These trends present important public health and clinical challenges...
  35. ncbi request reprint Racial and ethnic disparities in breast cancer stage, treatment, and survival in the United States
    Christopher I Li
    Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
    Ethn Dis 15:S5-9. 2005
    ....
  36. ncbi request reprint Postmenopausal hormone therapy and the risk of breast cancer: the view of an epidemiologist
    Christopher I Li
    Fred Hutchinson Cancer Research Center, University of Washington, 1100 Fairview Avenue North, M4 C308, Seattle, WA 98109 1024, USA
    Maturitas 49:44-50. 2004
    ..Numerous studies have evaluated the relationship between PMH and breast cancer risk because steroid hormones have been implicated in breast cancer etiology...
  37. ncbi request reprint The relationship between alcohol use and risk of breast cancer by histology and hormone receptor status among women 65-79 years of age
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 12:1061-6. 2003
    ..These results are consistent with there being an underlying hormonal basis for the known association between alcohol use and breast cancer incidence...
  38. ncbi request reprint Risk of mortality by histologic type of breast cancer among women aged 50 to 79 years
    Christopher I Li
    Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, Wash 98109, USA
    Arch Intern Med 163:2149-53. 2003
    ..Differences in survival rates by histologic types of tumor have been reported, but few of the published studies were population based or had adequate power to address this issue...
  39. ncbi request reprint Reproductive and anthropometric factors in relation to the risk of lobular and ductal breast carcinoma among women 65-79 years of age
    Christopher I Li
    Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, WA 98109, USA
    Int J Cancer 107:647-51. 2003
    ....
  40. ncbi request reprint Multiple primary breast and thyroid cancers: role of age at diagnosis and cancer treatments (United States)
    C I Li
    Fred Hutchinson Cancer Research Center, Program in Epidemiology, Division of Public Health Sciences, Seattle, Washington 98104, USA
    Cancer Causes Control 11:805-11. 2000
    ..The study presented herein focuses on the effects of age at diagnosis and treatment for the first cancer on the development of the second cancer...
  41. pmc Detection of elevated plasma levels of epidermal growth factor receptor before breast cancer diagnosis among hormone therapy users
    Sharon J Pitteri
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Cancer Res 70:8598-606. 2010
    ..Further studies are warranted to examine the role of EGFR and to discover and validate other proteins that could potentially be used for early detection of breast cancer...
  42. pmc Genetic variation in the progesterone receptor and metabolism pathways and hormone therapy in relation to breast cancer risk
    Kerryn W Reding
    Department of Epidemiology, School of Public Health, University of Washington, Seattle, Washington 98109, USA
    Am J Epidemiol 170:1241-9. 2009
    ..1, 2.2) but not in never users (P(heterogeneity) = 0.02). Interpretation of these subgroup associations must await the results of similar studies conducted in other populations...
  43. doi request reprint Timing of menarche and first birth in relation to risk of breast cancer in A-bomb survivors
    Jean A McDougall
    Department of Epidemiology, University of Washington, Health Sciences F 263, Box 357236, Seattle, WA 98195 7236, USA
    Cancer Epidemiol Biomarkers Prev 19:1746-54. 2010
    ....
  44. pmc Migraine in postmenopausal women and the risk of invasive breast cancer
    Robert W Mathes
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 17:3116-22. 2008
    ..Given the strong relationship between endogenous estrogen levels and breast cancer risk, migraine sufferers may experience a reduced risk of breast cancer...
  45. ncbi request reprint Survival differences by race in nasopharyngeal carcinoma
    Li Min Sun
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Am J Epidemiol 165:271-8. 2007
    ..Despite having higher incidence rates of NPC compared with other groups, Chinese NPC patients in the United States have better overall survival and the same risks of NPC-related mortality compared with other racial/ethnic groups...
  46. pmc Genetic polymorphisms in the catechol estrogen metabolism pathway and breast cancer risk
    Kerryn W Reding
    University of Washington, Seattle, WA 98109, USA
    Cancer Epidemiol Biomarkers Prev 18:1461-7. 2009
    ....
  47. pmc Factors affecting risk of mortality in women with vaginal cancer
    Chirag A Shah
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Washington, Seattle, Washington 98195 6460, USA
    Obstet Gynecol 113:1038-45. 2009
    ..To estimate the current effect of demographics, pathology, and treatment on mortality among women with vaginal cancer...
  48. ncbi request reprint Racial and ethnic disparities in cervical cancer incidence rates in the United States, 1992-2003
    Jean A McDougall
    Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Cancer Epidemiology Research Cooperative Studies M4 C308, Seattle, WA 98109 1024, USA
    Cancer Causes Control 18:1175-86. 2007
    ..Differences in cervical cancer incidence rates by race/ethnicity persist in the United States. We examined these differences by histologic type and by various patient and socioeconomic characteristics...
  49. pmc Body size, physical activity, and risk of triple-negative and estrogen receptor-positive breast cancer
    Amanda I Phipps
    Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M4 B402, P O Box 19024, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 20:454-63. 2011
    ..Focusing on potentially modifiable breast cancer risk factors, we examined the relationship between body size, physical activity, and triple-negative disease risk...
  50. pmc Family history of breast cancer in first-degree relatives and triple-negative breast cancer risk
    Amanda I Phipps
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, M4 B402, PO Box 19024, Seattle, WA 98109 1024, USA
    Breast Cancer Res Treat 126:671-8. 2011
    ..Having a first-degree family history of breast cancer was associated with an increased risk of triple-negative breast cancer with a magnitude of association similar to that for the predominant ER+ subtype and ER-/PR-/HER2+ breast cancer...
  51. pmc Reproductive history and oral contraceptive use in relation to risk of triple-negative breast cancer
    Amanda I Phipps
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Natl Cancer Inst 103:470-7. 2011
    ..Hormonally mediated risk factors may be differentially related to risk of triple-negative and ER+ breast cancers...
  52. ncbi request reprint Differences in colorectal carcinoma stage and survival by race and ethnicity
    Chloe Chien
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA
    Cancer 104:629-39. 2005
    ..Data regarding other races/ethnicities were limited, especially for Asian/Pacific Islander and Hispanic white subgroups...
  53. ncbi request reprint Antidepressant use and breast cancer risk
    Chloe Chien
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Breast Cancer Res Treat 95:131-40. 2006
    ..However, human studies evaluating use of antidepressants in relation to breast cancer risk have yielded inconsistent results...
  54. ncbi request reprint Trends in the incidence rates of nasopharyngeal carcinoma among Chinese Americans living in Los Angeles County and the San Francisco metropolitan area, 1992-2002
    Li Min Sun
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Am J Epidemiol 162:1174-8. 2005
    ..While the reasons underlying the observed patterns of incidence remain to be determined, changes in lifestyle and environment are likely to be contributory factors...
  55. pmc Reproductive history and risk of three breast cancer subtypes defined by three biomarkers
    Amanda I Phipps
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M4 B402, Seattle, WA 98109 1024, USA
    Cancer Causes Control 22:399-405. 2011
    ..31-2.56). Neither parity nor age at first birth was associated with triple-negative breast cancer. In contrast to ER+ and ER-/PR-/HER2+ subtypes, reproductive history does not appear to be a risk factor for triple-negative breast cancer...
  56. pmc Feasibility of including cellular telephone numbers in random digit dialing for epidemiologic case-control studies
    Lynda F Voigt
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer ResearchCenter, Seattle, Washington, USA
    Am J Epidemiol 173:118-26. 2011
    ....
  57. pmc Reproductive factors, age at maximum height, and risk of three histologic types of breast cancer
    Elisabeth F Beaber
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 17:3427-34. 2008
    ..5-0.9) but not lobular or ductal-lobular carcinoma. Further exploration of breast cancer risk by histology is merited to understand differences in the etiology of ductal, lobular, and ductal-lobular carcinoma...
  58. pmc Risk factors for ductal, lobular, and mixed ductal-lobular breast cancer in a screening population
    Amanda I Phipps
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 19:1643-54. 2010
    ..We compared associations between several factors and risk of ductal, lobular, and mixed ductal-lobular breast cancers...
  59. doi request reprint Relationship between histamine2-receptor antagonist medications and risk of invasive breast cancer
    Robert W Mathes
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 17:67-72. 2008
    ..The few previous studies evaluating this association have been null but have been limited by small sample sizes, and none have evaluated risk by either histologic type or estrogen receptor/progesterone receptor status...
  60. pmc Population-based estimates of the relation between breast cancer risk, tumor subtype, and family history
    Megan L Welsh
    Department of Epidemiology, University of Washington, Seattle, WA, USA
    Breast Cancer Res Treat 114:549-58. 2009
    ..We provide population-based estimates of breast cancer risk and different tumor subtypes in relation to the degree, number, and age at diagnosis of affected relatives...
  61. pmc Body size and risk of luminal, HER2-overexpressing, and triple-negative breast cancer in postmenopausal women
    Amanda I Phipps
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 17:2078-86. 2008
    ..Given the expanding obesity epidemic, the widespread cessation of hormone therapy use, and the poor prognosis of triple-negative tumors, this novel finding merits confirmation...
  62. pmc Reproductive and hormonal risk factors for postmenopausal luminal, HER-2-overexpressing, and triple-negative breast cancer
    Amanda I Phipps
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Cancer 113:1521-6. 2008
    ..Reproductive factors may plausibly be differentially correlated with the risk of different breast cancer subtypes because these factors are presumed to impact exposure to endogenous sex hormones...
  63. ncbi request reprint Neonatal encephalopathy and socioeconomic status: population-based case-control study
    Heidi K Blume
    Division of Pediatric Neurology, Children s Hospital and Regional Medical Center, University of Washington, Seattle, WA 98105, USA
    Arch Pediatr Adolesc Med 161:663-8. 2007
    ..To investigate the association between maternal socioeconomic status and the risk of encephalopathy in full-term newborns...
  64. ncbi request reprint Autoantibody signatures involving glycolysis and splicesome proteins precede a diagnosis of breast cancer among postmenopausal women
    Jon J Ladd
    Fred Hutchinson Cancer Research Center and Tumor Vaccine Group, University of Washington, Seattle, WA 98109, USA
    Cancer Res 73:1502-13. 2013
    ..We provide evidence for dynamic changes in autoantibody reactivity with tumor development and progression that may depend, in part, on the extent of antigen-antibody interactions...
  65. pmc Biases introduced by choosing controls to match risk factors of cases in biomarker research
    Margaret Sullivan Pepe
    Biostatistics and Biomathematics Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Clin Chem 58:1242-51. 2012
    ..Such matching, however, biases estimates of biomarker prediction performance. The magnitudes of these biases are unknown...
  66. ncbi request reprint Array comparative genomic hybridization analysis of genomic alterations in breast cancer subtypes
    Lenora W M Loo
    Division of Human Biology, Division of Public Health Sciences, and Genomics Shared Resource, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Cancer Res 64:8541-9. 2004
    ..These results indicate that array comparative genomic hybridization can identify significant differences in the genomic alterations between subtypes of breast cancer...
  67. ncbi request reprint Differences in survival by histologic type of pancreatic cancer
    Megan Dann Fesinmeyer
    Department of Epidemiology and Institute for Public Health Genetics, School of Public Health and Community Medicine, University of Washington, HSB F 363, Box 357236, 1959 Northeast Pacific Avenue, Seattle, WA 98195 7236, USA
    Cancer Epidemiol Biomarkers Prev 14:1766-73. 2005
    ..We examined median survival and risk of mortality for endocrine pancreatic tumors and two types of exocrine tumors, adenocarcinomas, and mucinous tumors...
  68. ncbi request reprint Differences in survival among patients with urachal and nonurachal adenocarcinomas of the bladder
    Jonathan L Wright
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Cancer 107:721-8. 2006
    ..The current study compares disease-specific characteristics and survival associated with urachal and nonurachal primary bladder adenocarcinomas...
  69. doi request reprint Intrapartum fever and chorioamnionitis as risks for encephalopathy in term newborns: a case-control study
    Heidi K Blume
    Division of Pediatric Neurology, Children s Hospital and Regional Medical Center, Seattle, WA 98105, USA
    Dev Med Child Neurol 50:19-24. 2008
    ..Infants born to women with signs of chorioamnionitis other than isolated intrapartum fever may be at higher risk of encephalopathy than those exposed only to isolated intrapartum fever...
  70. pmc C-reactive protein, interleukin-6, and prostate cancer risk in men aged 65 years and older
    Brandon L Pierce
    Institute for Public Health Genetics, University of Washington, Seattle, WA, USA
    Cancer Causes Control 20:1193-203. 2009
    ..21). Our results suggest that circulating CRP and IL-6 do not influence PCa risk. SNPs at the CRP locus are not associated with PCa risk in this cohort, while the association between rs1800795 and PCa risk warrants further investigation...
  71. pmc Relationship between menopausal symptoms and risk of postmenopausal breast cancer
    Yi Huang
    Department of Epidemiology, University of Washington, Seattle, Washington, USA
    Cancer Epidemiol Biomarkers Prev 20:379-88. 2011
    ..However, no prior studies have evaluated the association between menopausal symptoms and breast cancer risk...
  72. ncbi request reprint Re: "studies with low response proportions may be less biased than studies with high response proportions"
    Lynda F Voigt
    Am J Epidemiol 161:401-2; author reply 402-3. 2005

Research Grants15

  1. Tamoxifen & Second Breast Cancer: Epidemiology/Pathology
    Christopher Li; Fiscal Year: 2005
    ..which women have increased or decreased risks of developing CBC if they use tamoxifen? (4) Among the CBC cases, how does tamoxifen alter the expression of these tumor markers in first compared to contralateral cancers? ..
  2. Risk Factors for Second Primary Breast Cancer Among DCIS Survivors
    Christopher I Li; Fiscal Year: 2010
    ....
  3. Depo-Provera and Breast Cancer: Epidemiology/Pathology
    Christopher Li; Fiscal Year: 2009
    ..such as parity and body mass index, modify this association?; and (3) Does the association between DMPA and breast cancer risk vary by histologic type or by the expression of steroid receptors including ERq, ERft, and PR? ..
  4. c-erbB-2 and Risk of Contralateral Breast Cancer
    Christopher Li; Fiscal Year: 2007
    ....
  5. Depo-Provera and Breast Cancer: Epidemiology/Pathology
    Christopher Li; Fiscal Year: 2007
    ..such as parity and body mass index, modify this association?; and (3) Does the association between DMPA and breast cancer risk vary by histologic type or by the expression of steroid receptors including ERq, ERft, and PR? ..
  6. Protein Biomarkers of Cancer Risk in Older Persons
    Christopher Li; Fiscal Year: 2007
    ....
  7. Tamoxifen & Second Breast Cancer: Epidemiology/Pathology
    Christopher Li; Fiscal Year: 2007
    ..which women have increased or decreased risks of developing CBC if they use tamoxifen? (4) Among the CBC cases, how does tamoxifen alter the expression of these tumor markers in first compared to contralateral cancers? ..
  8. Depo-Provera and Breast Cancer: Epidemiology/Pathology
    Christopher Li; Fiscal Year: 2006
    ..such as parity and body mass index, modify this association?; and (3) Does the association between DMPA and breast cancer risk vary by histologic type or by the expression of steroid receptors including ERq, ERft, and PR? ..
  9. Protein Biomarkers of Cancer Risk in Older Persons
    Christopher Li; Fiscal Year: 2006
    ....
  10. Tamoxifen & Second Breast Cancer: Epidemiology/Pathology
    Christopher Li; Fiscal Year: 2006
    ..which women have increased or decreased risks of developing CBC if they use tamoxifen? (4) Among the CBC cases, how does tamoxifen alter the expression of these tumor markers in first compared to contralateral cancers? ..
  11. Protein Biomarkers of Cancer Risk in Older Persons
    Christopher Li; Fiscal Year: 2005
    ....
  12. Depo-Provera and Breast Cancer: Epidemiology/Pathology
    Christopher Li; Fiscal Year: 2005
    ..such as parity and body mass index, modify this association?; and (3) Does the association between DMPA and breast cancer risk vary by histologic type or by the expression of steroid receptors including ERq, ERft, and PR? ..
  13. Depo-Provera and Breast Cancer: Epidemiology/Pathology
    Christopher Li; Fiscal Year: 2009
    ..such as parity and body mass index, modify this association?; and (3) Does the association between DMPA and breast cancer risk vary by histologic type or by the expression of steroid receptors including ERq, ERft, and PR? ..