Research Topics
Species | Christopher LiSummaryAffiliation: Fred Hutchinson Cancer Research Center Country: USA Publications
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Publications
Reproductive factors and risk of estrogen receptor positive, triple-negative, and HER2-neu overexpressing breast cancer among women 20-44 years of ageChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M4 C 308, P O Box 19024, Seattle, WA 98109 1024, USA
Breast Cancer Res Treat 137:579-87. 2013..Further studies clarifying the biological mechanisms underlying this relationship and confirming our results with respect to age at first birth and the interval between age at menarche and age at first birth are needed...
Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational studyChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Breast Cancer Res Treat 135:611-8. 2012..Further research is required to followup on promising candidates in larger sample sizes and to better understand their potential biologic importance as our understanding of the etiology of triple-negative breast cancer continues to grow...
Effect of depo-medroxyprogesterone acetate on breast cancer risk among women 20 to 44 years of ageChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Cancer Res 72:2028-35. 2012....
Hormone receptor status, tumor characteristics, and prognosis: a prospective cohort of breast cancer patientsLisa K Dunnwald
Department of Epidemiology, University of Washington, Box 356113, 1959 NE Pacific St, Seattle, WA 98195, USA
Breast Cancer Res 9:R6. 2007..However, few studies have evaluated variations in the risks of breast cancer-specific mortality across ER/PR status by either demographic or clinical characteristics...
Changes in breast cancer incidence rates in the United States by histologic subtype and race/ethnicity, 1995 to 2004Christopher I Li
Division of Public Health Science, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 16:2773-80. 2007..The declines observed thus far are likely attributable to saturation of screening, although further declines related to the widespread cessation of hormone use may follow...
Timing of menarche and first full-term birth in relation to breast cancer riskChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Am J Epidemiol 167:230-9. 2008..The authors conclude that the interval between age at menarche and age at first birth is associated with the risk of hormonally sensitive types of breast cancer, particularly among White women...
Relationship between age maximum height is attained, age at menarche, and age at first full-term birth and breast cancer riskChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 16:2144-9. 2007....
Relationship between established breast cancer risk factors and risk of seven different histologic types of invasive breast cancerChristopher I Li
Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 15:946-54. 2006....
Interactions between body mass index and hormone therapy and postmenopausal breast cancer risk (United States)Christopher I Li
Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, 1100 Fairview Avenue North, M4 C308, 19024, Seattle, Washington 98109 1024, USA
Cancer Causes Control 17:695-703. 2006..To assess interactions between use of estrogen plus progestin hormone therapy (EPHT) and body mass index (BMI) in relation to risks of different types of breast cancer, based on histology and hormone receptor status...
Risk of invasive breast carcinoma among women diagnosed with ductal carcinoma in situ and lobular carcinoma in situ, 1988-2001Christopher I Li
Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Epidemiology Program, Seattle, Washington, USA
Cancer 106:2104-12. 2006..Incidence rates of ductal carcinoma in situ (DCIS) and lobular carcinoma in situ (LCIS) have been rising, but little is known about which patients will develop invasive breast cancer or what types of tumors these patients may develop...
Relationship between menopausal hormone therapy and risk of ductal, lobular, and ductal-lobular breast carcinomasChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 17:43-50. 2008..Further studies focusing on the etiology of lobular carcinomas are needed...
Relationship between migraine history and breast cancer risk among premenopausal and postmenopausal womenChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 18:2030-4. 2009..It extends the prior report in observing that this relationship holds for both premenopausal and postmenopausal women and is independent of exposure to common migraine triggers...
Adjuvant hormonal therapy for breast cancer and risk of hormone receptor-specific subtypes of contralateral breast cancerChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Cancer Res 69:6865-70. 2009..This is of clinical concern given the poorer prognosis of ER- compared with ER+ tumors...
Relationship between potentially modifiable lifestyle factors and risk of second primary contralateral breast cancer among women diagnosed with estrogen receptor-positive invasive breast cancerChristopher I Li
Divisions of Public Health Sciences and Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
J Clin Oncol 27:5312-8. 2009..We evaluated the relationships between obesity, alcohol consumption, and smoking on risk of second primary invasive contralateral breast cancer among breast cancer survivors...
Migraine history and breast cancer risk among postmenopausal womenChristopher I Li
Fred Hutchinson Cancer Research Center, 1100 N Fairview Ave, M4 C308, Seattle, WA 98109 1024, USA
J Clin Oncol 28:1005-10. 2010..06). CONCLUSION This study supports the hypothesis that a history of migraine is associated with a lower risk of breast cancer and that this relationship is independent of recent NSAID use...
Relationship between diabetes and risk of second primary contralateral breast cancerChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109 1024, USA
Breast Cancer Res Treat 125:545-51. 2011..This is the first study to report this relationship, but if confirmed efforts to insure that diabetic breast cancer survivors are carefully screened for second breast cancers may be warranted...
Alcohol consumption and risk of postmenopausal breast cancer by subtype: the women's health initiative observational studyChristopher I Li
Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
J Natl Cancer Inst 102:1422-31. 2010..This association is thought to be largely hormonally driven, so alcohol use may be more strongly associated with hormonally sensitive breast cancers. Few studies have evaluated how alcohol-related risk varies by breast cancer subtype...
Relationship between radiation exposure and risk of second primary cancers among atomic bomb survivorsChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Departments of Epidemiology and Biostatistics, University of Washington, Seattle, WA 98109 1024, USA
Cancer Res 70:7187-98. 2010..Radiation is a potent carcinogen and those with substantial exposures who are diagnosed with a first primary cancer should be carefully screened for second primary cancers, particularly for cancers that are radiation-sensitive...
Discovery and validation of breast cancer early detection biomarkers in preclinical samplesChristopher I Li
Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Horm Cancer 2:125-31. 2011....
Risk of mortality by histologic type of breast cancer in the United StatesChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Horm Cancer 1:156-65. 2010..Though many of these histologic subtypes are quite rare, consideration of the mortality risk associated with a given subtype may be clinically useful when making decisions regarding treatment and follow-up...
Clinical characteristics of different histologic types of breast cancerC I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M4 C308, PO Box 19024, Seattle, WA 98109 1024, USA
Br J Cancer 93:1046-52. 2005..The histologic types of breast cancer studied here differ greatly in their clinical presentations, and the differences in their hormone receptor profiles and grades point to their likely different aetiologies...
The relationship between various measures of cigarette smoking and risk of breast cancer among older women 65-79 years of age (United States)Christopher I Li
Division of Public Health Sciences, Epidemiology Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Cancer Causes Control 16:975-85. 2005..A further understanding of the timing of smoking, and its interaction with other factors, may enhance our knowledge of whether and by what mechanisms smoking alters breast cancer risk...
Postmenopausal hormone therapy and the risk of breast cancer: the view of an epidemiologistChristopher I Li
Fred Hutchinson Cancer Research Center, University of Washington, 1100 Fairview Avenue North, M4 C308, Seattle, WA 98109 1024, USA
Maturitas 49:44-50. 2004..Numerous studies have evaluated the relationship between PMH and breast cancer risk because steroid hormones have been implicated in breast cancer etiology...
Risk of mortality by histologic type of breast cancer among women aged 50 to 79 yearsChristopher I Li
Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, Wash 98109, USA
Arch Intern Med 163:2149-53. 2003..Differences in survival rates by histologic types of tumor have been reported, but few of the published studies were population based or had adequate power to address this issue...
Incidence of invasive breast cancer by hormone receptor status from 1992 to 1998Christopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
J Clin Oncol 21:28-34. 2003..This is because hormone receptor status may reflect different etiologic pathways and is useful in predicting response to adjuvant therapy and prognosis...
Differences in breast cancer stage, treatment, and survival by race and ethnicityChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, MP 381, PO Box 19024, Seattle, WA 98109 1024, USA
Arch Intern Med 163:49-56. 2003..However, Asians and Pacific Islanders and Hispanic whites are heterogeneous populations, and few studies have evaluated breast cancer stage, treatments, and mortality rates for subgroups of these populations...
Trends in incidence rates of invasive lobular and ductal breast carcinomaChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, MP 381, PO Box 19024, Seattle, Wash 98109 1024, USA
JAMA 289:1421-4. 2003..Lobular carcinoma is less common than ductal carcinoma but can be more difficult to diagnose because of its subtle elusive infiltrative pattern...
Birthweight and risk of overall and cause-specific childhood mortalityChristopher I Li
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Paediatr Perinat Epidemiol 17:164-70. 2003..Our results suggest that birthweight exerts important influences on children's risk of age-specific and cause-specific mortalities, particularly those with a strong biological component...
Reproductive and anthropometric factors in relation to the risk of lobular and ductal breast carcinoma among women 65-79 years of ageChristopher I Li
Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, WA 98109, USA
Int J Cancer 107:647-51. 2003....
Relation between use of antihypertensive medications and risk of breast carcinoma among women ages 65-79 yearsChristopher I Li
Public Health Sciences Division, Epidemiology Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
Cancer 98:1504-13. 2003....
Epidemiologic and molecular risk factors for contralateral breast cancer among young womenC I Li
Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, 1100 Fairview Avenue North, MP 381, PO Box 19024, Seattle, WA 98109 1024, USA
Br J Cancer 89:513-8. 2003..Further observational studies are needed to confirm these findings and to evaluate whether testing for c-erbB-2 in this population may help identify those at high risk for CBC...
The relationship between alcohol use and risk of breast cancer by histology and hormone receptor status among women 65-79 years of ageChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 12:1061-6. 2003..These results are consistent with there being an underlying hormonal basis for the known association between alcohol use and breast cancer incidence...
Relationship between long durations and different regimens of hormone therapy and risk of breast cancerChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
JAMA 289:3254-63. 2003..Women using combined estrogen and progestin hormone replacement therapy (CHRT) have an increased risk of breast cancer; however, data on use for long durations and on risk associated with patterns of use are lacking...
Age-specific incidence rates of in situ breast carcinomas by histologic type, 1980 to 2001Christopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 14:1008-11. 2005..These trends present important public health and clinical challenges...
Changing incidence of lobular carcinoma in situ of the breastChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Breast Cancer Res Treat 75:259-68. 2002..48/100,000 person-years). LCIS incidence rates have steadily increased from 1978 to 1998 only among postmenopausal women. Further research is required to assess what factors are contributing to these trends...
Differences in breast cancer hormone receptor status and histology by race and ethnicity among women 50 years of age and olderChristopher I Li
Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, Washington 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 11:601-7. 2002..Understanding the factors underlying these differences may provide further insight into breast cancer etiology in different populations...
Tamoxifen therapy for primary breast cancer and risk of contralateral breast cancerC I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
J Natl Cancer Inst 93:1008-13. 2001..Tamoxifen therapy reduces this risk, but it is unclear if this benefit exists for both estrogen receptor (ER)-positive and ER-negative contralateral tumors...
Multiple primary breast and thyroid cancers: role of age at diagnosis and cancer treatments (United States)C I Li
Fred Hutchinson Cancer Research Center, Program in Epidemiology, Division of Public Health Sciences, Seattle, Washington 98104, USA
Cancer Causes Control 11:805-11. 2000..The study presented herein focuses on the effects of age at diagnosis and treatment for the first cancer on the development of the second cancer...
Racial and ethnic disparities in breast cancer stage, treatment, and survival in the United StatesChristopher I Li
Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
Ethn Dis 15:S5-9. 2005....
Detection of elevated plasma levels of epidermal growth factor receptor before breast cancer diagnosis among hormone therapy usersSharon J Pitteri
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
Cancer Res 70:8598-606. 2010..Further studies are warranted to examine the role of EGFR and to discover and validate other proteins that could potentially be used for early detection of breast cancer...
Genetic variation in the progesterone receptor and metabolism pathways and hormone therapy in relation to breast cancer riskKerryn W Reding
Department of Epidemiology, School of Public Health, University of Washington, Seattle, Washington 98109, USA
Am J Epidemiol 170:1241-9. 2009..1, 2.2) but not in never users (P(heterogeneity) = 0.02). Interpretation of these subgroup associations must await the results of similar studies conducted in other populations...
Timing of menarche and first birth in relation to risk of breast cancer in A-bomb survivorsJean A McDougall
Department of Epidemiology, University of Washington, Health Sciences F 263, Box 357236, Seattle, WA 98195 7236, USA
Cancer Epidemiol Biomarkers Prev 19:1746-54. 2010....
Migraine in postmenopausal women and the risk of invasive breast cancerRobert W Mathes
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 17:3116-22. 2008..Given the strong relationship between endogenous estrogen levels and breast cancer risk, migraine sufferers may experience a reduced risk of breast cancer...
Survival differences by race in nasopharyngeal carcinomaLi Min Sun
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Am J Epidemiol 165:271-8. 2007..Despite having higher incidence rates of NPC compared with other groups, Chinese NPC patients in the United States have better overall survival and the same risks of NPC-related mortality compared with other racial/ethnic groups...
Genetic polymorphisms in the catechol estrogen metabolism pathway and breast cancer riskKerryn W Reding
University of Washington, Seattle, WA 98109, USA
Cancer Epidemiol Biomarkers Prev 18:1461-7. 2009....
Factors affecting risk of mortality in women with vaginal cancerChirag A Shah
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Washington, Seattle, Washington 98195 6460, USA
Obstet Gynecol 113:1038-45. 2009..To estimate the current effect of demographics, pathology, and treatment on mortality among women with vaginal cancer...
Racial and ethnic disparities in cervical cancer incidence rates in the United States, 1992-2003Jean A McDougall
Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Cancer Epidemiology Research Cooperative Studies M4 C308, Seattle, WA 98109 1024, USA
Cancer Causes Control 18:1175-86. 2007..Differences in cervical cancer incidence rates by race/ethnicity persist in the United States. We examined these differences by histologic type and by various patient and socioeconomic characteristics...
Family history of breast cancer in first-degree relatives and triple-negative breast cancer riskAmanda I Phipps
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, M4 B402, PO Box 19024, Seattle, WA 98109 1024, USA
Breast Cancer Res Treat 126:671-8. 2011..Having a first-degree family history of breast cancer was associated with an increased risk of triple-negative breast cancer with a magnitude of association similar to that for the predominant ER+ subtype and ER-/PR-/HER2+ breast cancer...
Feasibility of including cellular telephone numbers in random digit dialing for epidemiologic case-control studiesLynda F Voigt
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer ResearchCenter, Seattle, Washington, USA
Am J Epidemiol 173:118-26. 2011....
Body size, physical activity, and risk of triple-negative and estrogen receptor-positive breast cancerAmanda I Phipps
Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M4 B402, P O Box 19024, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 20:454-63. 2011..Focusing on potentially modifiable breast cancer risk factors, we examined the relationship between body size, physical activity, and triple-negative disease risk...
Reproductive history and risk of three breast cancer subtypes defined by three biomarkersAmanda I Phipps
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M4 B402, Seattle, WA 98109 1024, USA
Cancer Causes Control 22:399-405. 2011..31-2.56). Neither parity nor age at first birth was associated with triple-negative breast cancer. In contrast to ER+ and ER-/PR-/HER2+ subtypes, reproductive history does not appear to be a risk factor for triple-negative breast cancer...
Reproductive history and oral contraceptive use in relation to risk of triple-negative breast cancerAmanda I Phipps
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
J Natl Cancer Inst 103:470-7. 2011..Hormonally mediated risk factors may be differentially related to risk of triple-negative and ER+ breast cancers...
Risk factors for ductal, lobular, and mixed ductal-lobular breast cancer in a screening populationAmanda I Phipps
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 19:1643-54. 2010..We compared associations between several factors and risk of ductal, lobular, and mixed ductal-lobular breast cancers...
Body size and risk of luminal, HER2-overexpressing, and triple-negative breast cancer in postmenopausal womenAmanda I Phipps
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 17:2078-86. 2008..Given the expanding obesity epidemic, the widespread cessation of hormone therapy use, and the poor prognosis of triple-negative tumors, this novel finding merits confirmation...
Trends in the incidence rates of nasopharyngeal carcinoma among Chinese Americans living in Los Angeles County and the San Francisco metropolitan area, 1992-2002Li Min Sun
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Am J Epidemiol 162:1174-8. 2005..While the reasons underlying the observed patterns of incidence remain to be determined, changes in lifestyle and environment are likely to be contributory factors...
Reproductive factors, age at maximum height, and risk of three histologic types of breast cancerElisabeth F Beaber
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 17:3427-34. 2008..5-0.9) but not lobular or ductal-lobular carcinoma. Further exploration of breast cancer risk by histology is merited to understand differences in the etiology of ductal, lobular, and ductal-lobular carcinoma...
Reproductive and hormonal risk factors for postmenopausal luminal, HER-2-overexpressing, and triple-negative breast cancerAmanda I Phipps
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
Cancer 113:1521-6. 2008..Reproductive factors may plausibly be differentially correlated with the risk of different breast cancer subtypes because these factors are presumed to impact exposure to endogenous sex hormones...
Population-based estimates of the relation between breast cancer risk, tumor subtype, and family historyMegan L Welsh
Department of Epidemiology, University of Washington, Seattle, WA, USA
Breast Cancer Res Treat 114:549-58. 2009..We provide population-based estimates of breast cancer risk and different tumor subtypes in relation to the degree, number, and age at diagnosis of affected relatives...
Relationship between histamine2-receptor antagonist medications and risk of invasive breast cancerRobert W Mathes
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 17:67-72. 2008..The few previous studies evaluating this association have been null but have been limited by small sample sizes, and none have evaluated risk by either histologic type or estrogen receptor/progesterone receptor status...
Antidepressant use and breast cancer riskChloe Chien
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Breast Cancer Res Treat 95:131-40. 2006..However, human studies evaluating use of antidepressants in relation to breast cancer risk have yielded inconsistent results...
Differences in colorectal carcinoma stage and survival by race and ethnicityChloe Chien
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA
Cancer 104:629-39. 2005..Data regarding other races/ethnicities were limited, especially for Asian/Pacific Islander and Hispanic white subgroups...
Neonatal encephalopathy and socioeconomic status: population-based case-control studyHeidi K Blume
Division of Pediatric Neurology, Children s Hospital and Regional Medical Center, University of Washington, Seattle, WA 98105, USA
Arch Pediatr Adolesc Med 161:663-8. 2007..To investigate the association between maternal socioeconomic status and the risk of encephalopathy in full-term newborns...
Autoantibody signatures involving glycolysis and splicesome proteins precede a diagnosis of breast cancer among postmenopausal womenJon J Ladd
Fred Hutchinson Cancer Research Center and Tumor Vaccine Group, University of Washington, Seattle, WA 98109, USA
Cancer Res 73:1502-13. 2013..We provide evidence for dynamic changes in autoantibody reactivity with tumor development and progression that may depend, in part, on the extent of antigen-antibody interactions...
Biases introduced by choosing controls to match risk factors of cases in biomarker researchMargaret Sullivan Pepe
Biostatistics and Biomathematics Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Clin Chem 58:1242-51. 2012..Such matching, however, biases estimates of biomarker prediction performance. The magnitudes of these biases are unknown...
Differences in survival among patients with urachal and nonurachal adenocarcinomas of the bladderJonathan L Wright
Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
Cancer 107:721-8. 2006..The current study compares disease-specific characteristics and survival associated with urachal and nonurachal primary bladder adenocarcinomas...
Differences in survival by histologic type of pancreatic cancerMegan Dann Fesinmeyer
Department of Epidemiology and Institute for Public Health Genetics, School of Public Health and Community Medicine, University of Washington, HSB F-363, Box 357236, 1959 Northeast Pacific Avenue, Seattle, WA 98195-7236, USA
Cancer Epidemiol Biomarkers Prev 14:1766-73. 2005..A better understanding of these differences could contribute to identifying the underlying causes of pancreatic cancer and to improving survival rates across all histologic types...
Intrapartum fever and chorioamnionitis as risks for encephalopathy in term newborns: a case-control studyHeidi K Blume
Division of Pediatric Neurology, Children s Hospital and Regional Medical Center, Seattle, WA 98105, USA
Dev Med Child Neurol 50:19-24. 2008..Infants born to women with signs of chorioamnionitis other than isolated intrapartum fever may be at higher risk of encephalopathy than those exposed only to isolated intrapartum fever...
Array comparative genomic hybridization analysis of genomic alterations in breast cancer subtypesLenora W M Loo
Division of Human Biology, Division of Public Health Sciences, and Genomics Shared Resource, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Cancer Res 64:8541-9. 2004..These results indicate that array comparative genomic hybridization can identify significant differences in the genomic alterations between subtypes of breast cancer...
C-reactive protein, interleukin-6, and prostate cancer risk in men aged 65 years and olderBrandon L Pierce
Institute for Public Health Genetics, University of Washington, Seattle, WA, USA
Cancer Causes Control 20:1193-203. 2009..21). Our results suggest that circulating CRP and IL-6 do not influence PCa risk. SNPs at the CRP locus are not associated with PCa risk in this cohort, while the association between rs1800795 and PCa risk warrants further investigation...
Relationship between menopausal symptoms and risk of postmenopausal breast cancerYi Huang
Department of Epidemiology, University of Washington, Seattle, Washington, USA
Cancer Epidemiol Biomarkers Prev 20:379-88. 2011..However, no prior studies have evaluated the association between menopausal symptoms and breast cancer risk...
Re: "studies with low response proportions may be less biased than studies with high response proportions"Lynda F Voigt
Am J Epidemiol 161:401-2; author reply 402-3. 2005
Research Grants
- Risk Factors for Second Primary Breast Cancer Among DCIS SurvivorsChristopher I Li; Fiscal Year: 2010....
- c-erbB-2 and Risk of Contralateral Breast CancerChristopher Li; Fiscal Year: 2007....
- Depo-Provera and Breast Cancer: Epidemiology/PathologyChristopher Li; Fiscal Year: 2007..such as parity and body mass index, modify this association?; and (3) Does the association between DMPA and breast cancer risk vary by histologic type or by the expression of steroid receptors including ERq, ERft, and PR? ..
- Protein Biomarkers of Cancer Risk in Older PersonsChristopher Li; Fiscal Year: 2007....
- Tamoxifen & Second Breast Cancer: Epidemiology/PathologyChristopher Li; Fiscal Year: 2007..which women have increased or decreased risks of developing CBC if they use tamoxifen? (4) Among the CBC cases, how does tamoxifen alter the expression of these tumor markers in first compared to contralateral cancers? ..
- Depo-Provera and Breast Cancer: Epidemiology/PathologyChristopher Li; Fiscal Year: 2009..such as parity and body mass index, modify this association?; and (3) Does the association between DMPA and breast cancer risk vary by histologic type or by the expression of steroid receptors including ERq, ERft, and PR? ..
