Kerry J Laing

Summary

Affiliation: Fred Hutchinson Cancer Research Center
Country: USA

Publications

  1. pmc A genomic view of the NOD-like receptor family in teleost fish: identification of a novel NLR subfamily in zebrafish
    Kerry J Laing
    Department of Pathobiology, University of Washington, Seattle, Washington 98195, USA
    BMC Evol Biol 8:42. 2008
  2. pmc In situ detection of Gag-specific CD8+ cells in the GI tract of SIV infected Rhesus macaques
    Annelie Tjernlund
    Vaccine and Infectious Disease Institute, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Retrovirology 7:12. 2010
  3. pmc Immunity to fish rhabdoviruses
    Maureen K Purcell
    Western Fisheries Research Center, United States Geological Survey, 6505 NE 65th St, Seattle, WA 98115, USA
    Viruses 4:140-66. 2012
  4. doi request reprint Fish T cells: recent advances through genomics
    Kerry J Laing
    Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer, Research Center, Seattle, WA 98109, USA
    Dev Comp Immunol 35:1282-95. 2011
  5. doi request reprint Characterization of the interferon genes in homozygous rainbow trout reveals two novel genes, alternate splicing and differential regulation of duplicated genes
    Maureen K Purcell
    US Geological Survey, Western Fisheries Research Center, 6505 NE 65th St, Seattle, WA 98034, USA
    Fish Shellfish Immunol 26:293-304. 2009
  6. doi request reprint Description of an elasmobranch TCR coreceptor: CD8α from Rhinobatos productus
    John D Hansen
    U S Geological Survey, Western Fisheries Research Center, Seattle, WA 98115, USA
    Dev Comp Immunol 35:452-60. 2011
  7. ncbi request reprint Molecular and biochemical analysis of rainbow trout LCK suggests a conserved mechanism for T-cell signaling in gnathostomes
    Kerry J Laing
    Department of Pathobiology, University of Washington, Seattle, WA 98195, USA
    Mol Immunol 44:2737-48. 2007
  8. pmc Peripheral blood CD4 T-cell and plasmacytoid dendritic cell (pDC) reactivity to herpes simplex virus 2 and pDC number do not correlate with the clinical or virologic severity of recurrent genital herpes
    Nicholas J Moss
    Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, USA
    J Virol 86:9952-63. 2012
  9. ncbi request reprint Evolution of the CD4 family: teleost fish possess two divergent forms of CD4 in addition to lymphocyte activation gene-3
    Kerry J Laing
    Department of Pathobiology, University of Washington, Seattle WA 98195, USA
    J Immunol 177:3939-51. 2006
  10. pmc Protective HIV-specific CD8+ T cells evade Treg cell suppression
    Shokrollah Elahi
    Viral Vaccine Program, Seattle Biomedical Research Institute Seattle Biomed, Seattle, Washington, USA
    Nat Med 17:989-95. 2011

Collaborators

Detail Information

Publications14

  1. pmc A genomic view of the NOD-like receptor family in teleost fish: identification of a novel NLR subfamily in zebrafish
    Kerry J Laing
    Department of Pathobiology, University of Washington, Seattle, Washington 98195, USA
    BMC Evol Biol 8:42. 2008
    ....
  2. pmc In situ detection of Gag-specific CD8+ cells in the GI tract of SIV infected Rhesus macaques
    Annelie Tjernlund
    Vaccine and Infectious Disease Institute, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Retrovirology 7:12. 2010
    ..SIV and HIV predominantly replicate in lymphoid tissue, but the study of virus specific CD8+ T cells in intact lymphoid tissue is difficult, as traditional in situ tetramer staining requires fresh tissue...
  3. pmc Immunity to fish rhabdoviruses
    Maureen K Purcell
    Western Fisheries Research Center, United States Geological Survey, 6505 NE 65th St, Seattle, WA 98115, USA
    Viruses 4:140-66. 2012
    ....
  4. doi request reprint Fish T cells: recent advances through genomics
    Kerry J Laing
    Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer, Research Center, Seattle, WA 98109, USA
    Dev Comp Immunol 35:1282-95. 2011
    ..Although there is still a long way to go, major advances have occurred in recent years for investigating T cell responses, thus phenotypic and functional characterization is on the near horizon...
  5. doi request reprint Characterization of the interferon genes in homozygous rainbow trout reveals two novel genes, alternate splicing and differential regulation of duplicated genes
    Maureen K Purcell
    US Geological Survey, Western Fisheries Research Center, 6505 NE 65th St, Seattle, WA 98034, USA
    Fish Shellfish Immunol 26:293-304. 2009
    ..The specificity of the qRT-PCR assays reported here will be useful for future studies aimed at identifying which cells produce IFNs at early time points after infection...
  6. doi request reprint Description of an elasmobranch TCR coreceptor: CD8α from Rhinobatos productus
    John D Hansen
    U S Geological Survey, Western Fisheries Research Center, Seattle, WA 98115, USA
    Dev Comp Immunol 35:452-60. 2011
    ....
  7. ncbi request reprint Molecular and biochemical analysis of rainbow trout LCK suggests a conserved mechanism for T-cell signaling in gnathostomes
    Kerry J Laing
    Department of Pathobiology, University of Washington, Seattle, WA 98195, USA
    Mol Immunol 44:2737-48. 2007
    ....
  8. pmc Peripheral blood CD4 T-cell and plasmacytoid dendritic cell (pDC) reactivity to herpes simplex virus 2 and pDC number do not correlate with the clinical or virologic severity of recurrent genital herpes
    Nicholas J Moss
    Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, USA
    J Virol 86:9952-63. 2012
    ..These data suggest that other immune cell subsets with alternate phenotypes or anatomical locations may be responsible for genital herpes control in chronically infected individuals...
  9. ncbi request reprint Evolution of the CD4 family: teleost fish possess two divergent forms of CD4 in addition to lymphocyte activation gene-3
    Kerry J Laing
    Department of Pathobiology, University of Washington, Seattle WA 98195, USA
    J Immunol 177:3939-51. 2006
    ....
  10. pmc Protective HIV-specific CD8+ T cells evade Treg cell suppression
    Shokrollah Elahi
    Viral Vaccine Program, Seattle Biomedical Research Institute Seattle Biomed, Seattle, Washington, USA
    Nat Med 17:989-95. 2011
    ..This study uncovers a previously unknown explanation for why HLA-B*27 and HLA-B*57 allele groups are associated with delayed HIV-1 disease progression...
  11. ncbi request reprint Trout CC chemokines: comparison of their sequences and expression patterns
    Kerry J Laing
    Scottish Fish Immunology Research Centre, Zoology Building, School of Biological Sciences, University of Aberdeen, Tillydrone Avenue, Aberdeen AB24 2TZ, Scotland, UK
    Mol Immunol 41:793-808. 2004
    ..However, induction of some of the chemokines structurally related to 'inducible' CC chemokines was observed in a trout macrophage-like cell line (RTS-11) in response to stimulation with recombinant TNFalpha...
  12. ncbi request reprint Chemokines
    Kerry J Laing
    Scottish Fish Immunology Research Centre, School of Biological Sciences, University of Aberdeen, Zoology Building, Tillydrone Avenue, Aberdeen AB24 2TZ, UK
    Dev Comp Immunol 28:443-60. 2004
    ..This review aims to bring together the current information concerning identified chemokines throughout vertebrates and microorganisms...
  13. ncbi request reprint A CXC chemokine sequence isolated from the rainbow trout Oncorhynchus mykiss resembles the closely related interferon-gamma-inducible chemokines CXCL9, CXCL10 and CXCL11
    Kerry J Laing
    Dept of Zoology, University of Aberdeen, Scotland
    Eur Cytokine Netw 13:462-73. 2002
    ..Intraperitoneal injection of recombinant trout TNF-alpha caused elevation in gammaIP mRNA levels in trout head kidney...
  14. ncbi request reprint Identification and analysis of an interleukin 8-like molecule in rainbow trout Oncorhynchus mykiss
    Kerry J Laing
    Department of Zoology, University of Aberdeen, Tillydrone Avenue, Aberdeen, Scotland AB24 2TZ, UK
    Dev Comp Immunol 26:433-44. 2002
    ....