A Z LaCroix

Summary

Affiliation: Fred Hutchinson Cancer Research Center
Country: USA

Publications

  1. pmc OPG and sRANKL serum levels and incident hip fracture in postmenopausal Caucasian women in the Women's Health Initiative Observational Study
    Andrea Z LaCroix
    Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M3 A410, POB 19024, Seattle, WA 98109 1024, USA
    Bone 56:474-81. 2013
  2. pmc Effects of escitalopram on menopause-specific quality of life and pain in healthy menopausal women with hot flashes: a randomized controlled trial
    Andrea Z LaCroix
    Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Maturitas 73:361-8. 2012
  3. pmc Health outcomes after stopping conjugated equine estrogens among postmenopausal women with prior hysterectomy: a randomized controlled trial
    Andrea Z LaCroix
    Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M3 A410, PO 19024, Seattle, WA 98109
    JAMA 305:1305-14. 2011
  4. doi request reprint Breast cancer incidence in the randomized PEARL trial of lasofoxifene in postmenopausal osteoporotic women
    Andrea Z LaCroix
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Natl Cancer Inst 102:1706-15. 2010
  5. pmc Hip structural geometry and incidence of hip fracture in postmenopausal women: what does it add to conventional bone mineral density?
    A Z LaCroix
    WHI Clinical Coordinating Center, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Osteoporos Int 21:919-29. 2010
  6. pmc Calcium plus vitamin D supplementation and mortality in postmenopausal women: the Women's Health Initiative calcium-vitamin D randomized controlled trial
    Andrea Z LaCroix
    WHI Clinical Coordinating Center, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M3 A410, PO Box 19024, Seattle, WA 98109 1024, USA
    J Gerontol A Biol Sci Med Sci 64:559-67. 2009
  7. pmc Cystatin-C, renal function, and incidence of hip fracture in postmenopausal women
    Andrea Z LaCroix
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    J Am Geriatr Soc 56:1434-41. 2008
  8. ncbi request reprint Statin use and incident frailty in women aged 65 years or older: prospective findings from the Women's Health Initiative Observational Study
    Andrea Z LaCroix
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Gerontol A Biol Sci Med Sci 63:369-75. 2008
  9. ncbi request reprint Estrogen with and without progestin: benefits and risks of short-term use
    Andrea Z LaCroix
    Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Am J Med 118:79-87. 2005
  10. ncbi request reprint Bone mineral density and endogenous hormones and risk of breast cancer in postmenopausal women (United States)
    D S Buist
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Cancer Causes Control 12:213-22. 2001

Detail Information

Publications94

  1. pmc OPG and sRANKL serum levels and incident hip fracture in postmenopausal Caucasian women in the Women's Health Initiative Observational Study
    Andrea Z LaCroix
    Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M3 A410, POB 19024, Seattle, WA 98109 1024, USA
    Bone 56:474-81. 2013
    ..This study investigated associations between serum levels of OPG, soluble RANKL (sRANKL), and the ratio of OPG/sRANKL to risk of incident hip fracture...
  2. pmc Effects of escitalopram on menopause-specific quality of life and pain in healthy menopausal women with hot flashes: a randomized controlled trial
    Andrea Z LaCroix
    Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Maturitas 73:361-8. 2012
    ..To evaluate the effects of escitalopram 10-20 mg/day on menopause-related quality of life and pain in healthy menopausal women with hot flashes...
  3. pmc Health outcomes after stopping conjugated equine estrogens among postmenopausal women with prior hysterectomy: a randomized controlled trial
    Andrea Z LaCroix
    Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M3 A410, PO 19024, Seattle, WA 98109
    JAMA 305:1305-14. 2011
    ..1 years of follow-up because of an increased risk of stroke and little likelihood of altering the balance of risk to benefit by the planned trial termination date. Postintervention health outcomes have not been reported...
  4. doi request reprint Breast cancer incidence in the randomized PEARL trial of lasofoxifene in postmenopausal osteoporotic women
    Andrea Z LaCroix
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Natl Cancer Inst 102:1706-15. 2010
    ....
  5. pmc Hip structural geometry and incidence of hip fracture in postmenopausal women: what does it add to conventional bone mineral density?
    A Z LaCroix
    WHI Clinical Coordinating Center, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Osteoporos Int 21:919-29. 2010
    ....
  6. pmc Calcium plus vitamin D supplementation and mortality in postmenopausal women: the Women's Health Initiative calcium-vitamin D randomized controlled trial
    Andrea Z LaCroix
    WHI Clinical Coordinating Center, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M3 A410, PO Box 19024, Seattle, WA 98109 1024, USA
    J Gerontol A Biol Sci Med Sci 64:559-67. 2009
    ..This report examines intervention effects on total and cause-specific mortality by age and adherence...
  7. pmc Cystatin-C, renal function, and incidence of hip fracture in postmenopausal women
    Andrea Z LaCroix
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    J Am Geriatr Soc 56:1434-41. 2008
    ..To evaluate the association between chronic kidney disease and incident hip fracture using serum cystatin-C as a biomarker of renal function calculated without reference to muscle mass...
  8. ncbi request reprint Statin use and incident frailty in women aged 65 years or older: prospective findings from the Women's Health Initiative Observational Study
    Andrea Z LaCroix
    Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Gerontol A Biol Sci Med Sci 63:369-75. 2008
    ..This study examines associations between current use, duration, and potency of statin medications and incident frailty in initially nonfrail women 65 years old or older...
  9. ncbi request reprint Estrogen with and without progestin: benefits and risks of short-term use
    Andrea Z LaCroix
    Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Am J Med 118:79-87. 2005
    ..This pattern of risks and benefits is generally similar for women with vasomotor symptoms, women in their 50s, and women, with and without > or =1 intact ovary, who have had a hysterectomy...
  10. ncbi request reprint Bone mineral density and endogenous hormones and risk of breast cancer in postmenopausal women (United States)
    D S Buist
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Cancer Causes Control 12:213-22. 2001
    ....
  11. ncbi request reprint Bone mineral density in women using depot medroxyprogesterone acetate for contraception
    D Scholes
    Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, Washington 98101, USA
    Obstet Gynecol 93:233-8. 1999
    ..To evaluate the possible effects of depot medroxyprogesterone acetate injectable contraception on bone mineral density in reproductive-age women...
  12. ncbi request reprint Depressive symptoms in users and non-users of depot medroxyprogesterone acetate
    D Civic
    Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, Washington 98101, USA
    Contraception 61:385-90. 2000
    ..Our prospective analyses found an association between DMPA use and depressive symptoms but further research is needed to determine whether the relationship is causal...
  13. doi request reprint Effects of three years of low-dose thiazides on mineral metabolism in healthy elderly persons
    S M Ott
    University of Washington, 1959 NE Pacific Street, P O Box 356426, Seattle, WA 98195 6426, USA
    Osteoporos Int 19:1315-22. 2008
    ..Serum bicarbonate was consistently greater in the thiazide than in the placebo groups throughout the three years. These effects could be beneficial to the skeleton...
  14. ncbi request reprint Effects of contraceptive use on bone biochemical markers in young women
    S M Ott
    Departments of Medicine, University of Washington, and the Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, Washington 98195-6426, USA
    J Clin Endocrinol Metab 86:179-85. 2001
    ..086 +/- 0.085 g/cm(2) in the DMPA group, 1.103 +/- 0.095 g/cm(2) in the oral contraceptive group, and 1.093 +/- 0.090 g/cm(2) in nonusers (P = 0.051). The results suggest that in women using DMPA bone resorption exceeded bone formation...
  15. ncbi request reprint Hormone replacement therapy, prothrombotic mutations, and the risk of incident nonfatal myocardial infarction in postmenopausal women
    B M Psaty
    Cardiovascular Health Research Unit, 1730 Minor Ave, Suite 1360, Seattle, WA 98101, USA
    JAMA 285:906-13. 2001
    ....
  16. ncbi request reprint Understanding attitudes of older women toward hormone replacement therapy
    E A Phelan
    Department of Medicine, University of Washington, Seattle, Washington, USA
    Prev Med 32:49-56. 2001
    ..Little is known about factors that may explain different attitudes...
  17. ncbi request reprint Risk of recurrent coronary events in relation to use and recent initiation of postmenopausal hormone therapy
    S R Heckbert
    Cardiovascular Health Research Unit, University of Washington, 1730 Minor Ave, Suite 1360, Seattle, WA 98101 1448, USA
    Arch Intern Med 161:1709-13. 2001
    ..We assessed the risk of recurrent myocardial infarction or coronary heart disease death associated with the use and recent initiation of hormone therapy in women who survived a first myocardial infarction...
  18. ncbi request reprint Low-fat dietary pattern and risk of colorectal cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial
    Shirley A A Beresford
    Department of Epidemiology, University of Washington, Seattle, WA 98195 7236, USA
    JAMA 295:643-54. 2006
    ..Observational studies and polyp recurrence trials are not conclusive regarding the effects of a low-fat dietary pattern on risk of colorectal cancer, necessitating a primary prevention trial...
  19. pmc Inflammation and thrombosis biomarkers and incident frailty in postmenopausal women
    Alexander P Reiner
    Women s Health Initiative Clinical Coordinating Center, Fred Hutchinson Cancer Research Center, Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98195, USA
    Am J Med 122:947-54. 2009
    ....
  20. ncbi request reprint Bone mineral density and breast cancer risk in postmenopausal women
    D S Buist
    Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, WA 98101, USA
    J Clin Epidemiol 54:417-22. 2001
    ..9 (1.1, 3.2), 1.5 (0.8, 2.6), and 1.5 (0.8, 2.7), respectively. An examination of other factors important in determining BMD may help explain the positive association between BMD and breast cancer...
  21. pmc Delivery of primary care to women. Do women's health centers do it better?
    E A Phelan
    Department of Medicine, University of Washington, Seattle, USA
    J Gen Intern Med 15:8-15. 2000
    ..Women's health centers have been increasing in number but remain relatively unstudied. We examined patient expectations and quality of care at a hospital-based women's health center compared with those at a general medicine clinic...
  22. ncbi request reprint The physician's role in women's decision making about hormone replacement therapy
    K M Newton
    Center for Health Studies, Group Health Cooperative of Puget Sound, Seattle, Washington 98101, USA
    Obstet Gynecol 92:580-4. 1998
    ..To ascertain the sources of information women use when making decisions about hormone replacement therapy (HRT)...
  23. ncbi request reprint What factors account for hormone replacement therapy prescribing frequency?
    K M Newton
    Center for Health Studies, Group Health Cooperative, 1730 Minor Ave Suite 1600, Seattle, WA 98101, USA
    Maturitas 39:1-10. 2001
    ..The purpose of this study was to compare hormone replacement therapy (HRT) prescribing frequency to provider characteristics, attitudes and beliefs about menopause and HRT...
  24. ncbi request reprint Statin use, clinical fracture, and bone density in postmenopausal women: results from the Women's Health Initiative Observational Study
    Andrea Z LaCroix
    Women s Health Initiative Clinical Coordinating Center, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, MP 1002, PO Box 19024, Seattle, Washington 98109 1024, USA
    Ann Intern Med 139:97-104. 2003
    ..While early epidemiologic studies showed lower risk for hip fracture among statin users than nonusers, subsequent studies have produced mixed results...
  25. pmc Health risks and benefits from calcium and vitamin D supplementation: Women's Health Initiative clinical trial and cohort study
    R L Prentice
    Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Osteoporos Int 24:567-80. 2013
    ..0 years. The trial was designed to test whether calcium plus vitamin D supplementation in a population in which the use of these supplements was widespread would reduce hip fracture, and secondarily, total fracture and colorectal cancer...
  26. ncbi request reprint Colorectal cancer screening participation by older women
    M T Mandelson
    Center for Health Studies, Group Health Cooperative, Seattle, Washington, USA
    Am J Prev Med 19:149-54. 2000
    ..Systematic efforts to increase awareness of colorectal cancer (CRC) and to promote screening participation are needed to meet national objectives for CRC control...
  27. ncbi request reprint The relationship between breast density and bone mineral density in postmenopausal women
    Diana S M Buist
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Cancer 101:1968-76. 2004
    ..The authors examined the relationship between bone mineral density (BMD; a marker of lifetime estrogen exposure) and breast density...
  28. pmc Protein intake and incident frailty in the Women's Health Initiative observational study
    Jeannette M Beasley
    Clinical Coordinating Center, Women s Health Initiative, Fred Hutchinson Cancer Research Center, Seattle, Washington 98101, USA
    J Am Geriatr Soc 58:1063-71. 2010
    ..To evaluate the association between protein intake and incident frailty...
  29. ncbi request reprint Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial
    Garnet L Anderson
    Fred Hutchinson Cancer Research Center, Seattle, Wash 98109 1024, USA
    JAMA 291:1701-12. 2004
    ..Despite decades of use and considerable research, the role of estrogen alone in preventing chronic diseases in postmenopausal women remains uncertain...
  30. ncbi request reprint Low-fat dietary pattern and risk of invasive breast cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial
    Ross L Prentice
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Wash 98109, USA
    JAMA 295:629-42. 2006
    ..The hypothesis that a low-fat dietary pattern can reduce breast cancer risk has existed for decades but has never been tested in a controlled intervention trial...
  31. ncbi request reprint Dietary soy isoflavone intake in older Japanese American women
    M M Rice
    Department of Epidemiology, University of Washington, Seattle, WA 98195, USA
    Public Health Nutr 4:943-52. 2001
    ....
  32. ncbi request reprint Association between caffeine intake and bone mass among young women: potential effect modification by depot medroxyprogesterone acetate use
    C M Wetmore
    Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98195, USA
    Osteoporos Int 19:519-27. 2008
    ....
  33. ncbi request reprint Women's responses to a mailed hormone replacement therapy workbook
    K M Newton
    Center for Health Studies, Group Health Cooperative, Seattle, Washington 98101, USA
    Menopause 8:361-7. 2001
    ..Although numerous decision-making tools exist, few have been evaluated. The objective of this study was to examine women's use of a workbook designed to promote informed HRT decision-making...
  34. pmc Depressive symptoms and menopausal burden in the midlife
    Susan D Reed
    Group Health Center for Health Studies, Seattle, WA, USA
    Maturitas 62:306-10. 2009
    ..The goal of this study was to assess whether menopausal symptoms were more common and/or more severe among women with depressive symptoms...
  35. pmc Is protein intake associated with bone mineral density in young women?
    Jeannette M Beasley
    Group Health Research Institute, 1730 Minor Avenue, Suite 1600, Seattle, WA 98101, USA
    Am J Clin Nutr 91:1311-6. 2010
    ..The range of protein intakes for optimizing bone health among premenopausal women is unclear. Protein is a major constituent of bone, but acidic amino acids may promote bone resorption...
  36. pmc Depressive symptoms, bone loss, and fractures in postmenopausal women
    Leslie Spangler
    Group Health Center for Health Studies, Seattle, WA, USA
    J Gen Intern Med 23:567-74. 2008
    ..Osteoporosis and depression may be associated through common physiologic systems or risk factors...
  37. ncbi request reprint Indications for hormone therapy: the post-Women's Health Initiative era
    Susan D Reed
    Department of Obstetrics and Gynecology, University of Washington Harborview Medical Center, 325 9th Avenue, Box 359865, Seattle, WA 98115, USA
    Endocrinol Metab Clin North Am 33:691-715. 2004
    ....
  38. ncbi request reprint Biomechanical properties of shoes and risk of falls in older adults
    Allan F Tencer
    Harborview Injury Prevention and Research Center, Orthopedic Sciences Laboratory, Harborview Medical Center, MS 359798, 325 Ninth Avenue, Seattle, WA 98104, USA
    J Am Geriatr Soc 52:1840-6. 2004
    ..To determine the relationships between the biomechanical properties of shoes worn in a cohort of healthy older adults and the risk of falling...
  39. doi request reprint Proton pump inhibitor use, hip fracture, and change in bone mineral density in postmenopausal women: results from the Women's Health Initiative
    Shelly L Gray
    School of Pharmacy, University of Washington, Box 357630, Seattle, WA 98195, USA
    Arch Intern Med 170:765-71. 2010
    ..Proton pump inhibitor (PPI) medications have been inconsistently shown to be associated with osteoporotic fractures. We examined the association of PPI use with bone outcomes (fracture, bone mineral density [BMD])...
  40. ncbi request reprint A population-based osteoporosis screening program: who does not participate, and what are the consequences?
    Diana S M Buist
    Center for Health Studies, Group Health Cooperative, Seattle, Washington 98101, USA
    J Am Geriatr Soc 52:1130-7. 2004
    ..To describe differences in osteoporosis risk factors and rates of fracture and antiresorptive therapy use in women who did and did not participate in an osteoporosis screening program...
  41. ncbi request reprint Vaginal, endometrial, and reproductive hormone findings: randomized, placebo-controlled trial of black cohosh, multibotanical herbs, and dietary soy for vasomotor symptoms: the Herbal Alternatives for Menopause (HALT) Study
    Susan D Reed
    Group Health Center for Health Studies, Seattle, WA, USA
    Menopause 15:51-8. 2008
    ..To evaluate vaginal, endometrial, and reproductive hormone effects of three herbal regimens compared with placebo and hormone therapy (HT)...
  42. ncbi request reprint Frailty: emergence and consequences in women aged 65 and older in the Women's Health Initiative Observational Study
    Nancy Fugate Woods
    Seattle Clinical Center, Seattle, Washington 98195, USA
    J Am Geriatr Soc 53:1321-30. 2005
    ....
  43. ncbi request reprint Estrogen therapy and risk of cardiovascular events among women with type 2 diabetes
    Katherine M Newton
    Center for Health Studies, Group Health Cooperative, Seattle, Washington, USA
    Diabetes Care 26:2810-6. 2003
    ..To evaluate the association between estrogen therapy and cardiovascular disease risk among women with type 2 diabetes...
  44. ncbi request reprint The effects of black cohosh therapies on lipids, fibrinogen, glucose and insulin
    Leslie Spangler
    Center for Health Studies, Group Health, Seattle, WA 98101, USA
    Maturitas 57:195-204. 2007
    ..Little is known about its effect on other physiologic parameters that could result in untoward events. This study examines the effect of black cohosh on lipids, fibrinogen, glucose and insulin...
  45. ncbi request reprint Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo: a randomized trial
    Katherine M Newton
    Group Health Center for Health Studies, The University of Washington, and Fred Hutchinson Cancer Research Center, Seattle, Washington 98101, USA
    Ann Intern Med 145:869-79. 2006
    ..Herbal supplements are widely used for vasomotor symptoms...
  46. ncbi request reprint Evaluation of three population-based strategies for fracture prevention: results of the osteoporosis population-based risk assessment (OPRA) trial
    Andrea Z LaCroix
    Center for Health Studies, Group Health Cooperative, Seattle, Washington, USA
    Med Care 43:293-302. 2005
    ..The integration of bone density testing into well-designed fracture prevention programs that can be applied in populations has not been studied...
  47. ncbi request reprint Identifying postmenopausal women at high risk of fracture in populations: a comparison of three strategies
    Diana S M Buist
    Center for Health Studies, Group Health Cooperative of Puget Sound, 1730 Minor Avenue, Suite 1600, Seattle, WA 98101, USA
    J Am Geriatr Soc 50:1031-8. 2002
    ..A key study objective was to compare the proportion of postmenopausal women at high risk of fracture in a managed care population using several different definitions of who is at high risk...
  48. ncbi request reprint Implementation and effectiveness of a community-based health promotion program for older adults
    J I Wallace
    Department of Medicine, University of Washington, Seattle, USA
    J Gerontol A Biol Sci Med Sci 53:M301-6. 1998
    ....
  49. ncbi request reprint Soy protein and bone mineral density in older men and women: a randomized trial
    K M Newton
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Maturitas 55:270-7. 2006
    ..Test the hypothesis that soy isoflavone supplementation preserves bone mineral density (BMD) in men and women...
  50. doi request reprint Intentional weight loss and risk of lymphohematopoietic cancers
    Anneclaire J De Roos
    Epidemiology Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Cancer Causes Control 21:223-36. 2010
    ..We hypothesized that intentional weight loss may be associated with development of lymphohematopoietic cancers, based on observations of immune suppression following weight loss in short-term studies...
  51. ncbi request reprint Use of alternative therapies for menopause symptoms: results of a population-based survey
    Katherine M Newton
    Center for Health Studies, Group Health Cooperative, Seattle, Washington 98101, USA
    Obstet Gynecol 100:18-25. 2002
    ..To describe self-reported prevalence of the use of alternative therapies for menopause symptoms and subject characteristics associated with their use...
  52. pmc Night sweats, sleep disturbance, and depression associated with diminished libido in late menopausal transition and early postmenopause: baseline data from the Herbal Alternatives for Menopause Trial (HALT)
    Susan D Reed
    Center for Health Studies, Group Health Cooperative, University of Washington School of Medicine, Seattle, WA, USA
    Am J Obstet Gynecol 196:593.e1-7; discussion 593.e7. 2007
    ..The objective of the study was to evaluate the association of depression, sleep disturbance, and menopausal symptoms with diminished libido...
  53. ncbi request reprint The association between depot medroxyprogesterone acetate contraception and bone mineral density in adolescent women
    Delia Scholes
    The Center for Health Studies, Group Health Cooperative, 1730 Minor Avenue, 16th Floor, Seattle, WA, USA
    Contraception 69:99-104. 2004
    ..06). This study did not find a strong association between DMPA use and bone density. Further prospective evaluation of bone density changes with DMPA use and after DMPA discontinuation are needed in this age group...
  54. ncbi request reprint Older adults' views of "successful aging"--how do they compare with researchers' definitions?
    Elizabeth A Phelan
    Department of Medicine, Division of Gerontology and Geriatric Medicine, School of Public Health and Community Medicine, University of Washington, Seattle, Washington 98104, USA
    J Am Geriatr Soc 52:211-6. 2004
    ..To determine whether older adults have thought about aging and aging successfully and to compare their perceptions of successful aging with attributes of successful aging identified in the published literature...
  55. ncbi request reprint Longitudinal changes in bone density in relation to oral contraceptive use
    Susan D Reed
    Group Health Cooperative, Seattle, WA, USA
    Contraception 68:177-82. 2003
    ..All p-values for between-group differences were >0.55. In conclusion, within the limitations of this study, OCs did not appear to impact bone density over time in this cohort of reproductive-age women...
  56. pmc Oral contraceptive use and bone density in adolescent and young adult women
    Delia Scholes
    Group Health Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Contraception 81:35-40. 2010
    ..Most of the millions of oral contraceptive (OC) users are under 30 years of age and in the critical period for bone mass accrual...
  57. ncbi request reprint Change in bone mineral density among adolescent women using and discontinuing depot medroxyprogesterone acetate contraception
    Delia Scholes
    Center for Health Studies, Group Health Cooperative, Seattle, Wash 98101, USA
    Arch Pediatr Adolesc Med 159:139-44. 2005
    ..Adolescents, who are still gaining bone, may be particularly affected, but there has been little study of the association in adolescent users and none following discontinuation...
  58. ncbi request reprint Benzodiazepine use and physical performance in community-dwelling older women
    Shelly L Gray
    School of Pharmacy, University of Washington, Seattle, Washington 98195, USA
    J Am Geriatr Soc 51:1563-70. 2003
    ..To determine whether benzodiazepine use in older women increased the risk of decline in physical function...
  59. ncbi request reprint Risks for frequent antimicrobial-treated infections in postmenopausal women
    Denise M Boudreau
    School of Pharmacy, University of Washington, Seattle, Washington, USA
    Aging Clin Exp Res 15:12-8. 2003
    ..This study in postmenopausal women examines health-related conditions and behavioral factors that may increase the risk of frequent infections, defined as having, on average, one or more infections per year...
  60. doi request reprint Mortality risk associated with physical and verbal abuse in women aged 50 to 79
    Margaret W Baker
    School of Nursing, University of Washington, Seattle, Washington 98195, USA
    J Am Geriatr Soc 57:1799-809. 2009
    ..To investigate whether midlife and older women who reported prior-year physical abuse, verbal abuse, or both abuse types had higher mortality risk than peers who did not report prior-year abuse...
  61. ncbi request reprint The Herbal Alternatives for Menopause (HALT) Study: background and study design
    Katherine M Newton
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Maturitas 52:134-46. 2005
    ..Despite inherent challenges, the study of alternative therapies for menopause symptoms is a rewarding and important area deserving of further inquiry...
  62. ncbi request reprint Benzodiazepine use in older adults enrolled in a health maintenance organization
    Shelly L Gray
    University of Washington, School of Pharmacy, Seattle, Washington, USA
    Am J Geriatr Psychiatry 11:568-76. 2003
    ....
  63. ncbi request reprint Depression predicts revascularization procedures for 5 years after coronary angiography
    Mark D Sullivan
    Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington 98195, USA
    Psychosom Med 65:229-36. 2003
    ..Depression has been reported to increase cardiac event rates and functional impairment in patients with coronary disease. This article describes the impact of depression on subsequent healthcare utilization for such patients...
  64. pmc How the Women's Health Initiative (WHI) influenced physicians' practice and attitudes
    Terry M Bush
    Group Health Center for Health Studies, Seattle, WA 98101, USA
    J Gen Intern Med 22:1311-6. 2007
    ....
  65. ncbi request reprint Injectable hormone contraception and bone density: results from a prospective study
    Delia Scholes
    Center for Health Studies, Group Health Cooperative, Seattle, WA 98101, USA
    Epidemiology 13:581-7. 2002
    ..Depot medroxyprogesterone acetate (DMPA) injectable contraception may decrease bone density and increase the risk for osteoporosis in later life. Prospective data are scarce, especially of the effects of DMPA discontinuation on bone...
  66. pmc Navel jewelry artifacts and intravertebral variation in spine bone densitometry in adolescents and young women
    Susan M Ott
    Department of Medicine, School of Medicine, University of Washington, Seattle, WA 98195 6426, USA
    J Clin Densitom 12:84-8. 2009
    ..35 at L1 but -0.26 at L4. Thus, we found significant errors due to intravertebral variability. We suggest the optimal method of correcting for small artifacts is to erase the area under the artifact...
  67. pmc Angiotensin-converting enzyme inhibitor use and incident frailty in women aged 65 and older: prospective findings from the Women's Health Initiative Observational Study
    Shelly L Gray
    University of Washington, Seattle, 98195, USA
    J Am Geriatr Soc 57:297-303. 2009
    ..To examine the associations between current use, duration, and potency of angiotensin-converting enzyme (ACE) inhibitors and incident frailty in women aged 65 and older who were not frail at baseline...
  68. pmc Benzodiazepine use and physical disability in community-dwelling older adults
    Shelly L Gray
    School of Pharmacy, University of Washington, Seattle, Washington 98195, USA
    J Am Geriatr Soc 54:224-30. 2006
    ..To determine whether benzodiazepine use is associated with incident disability in mobility and activities of daily living (ADLs) in older individuals...
  69. pmc Usefulness of baseline lipids and C-reactive protein in women receiving menopausal hormone therapy as predictors of treatment-related coronary events
    Paul F Bray
    Cardeza Foundation for Hematologic Research and Jefferson Medical College, Philadelphia, Pennsylvania, USA
    Am J Cardiol 101:1599-1605. 2008
    ..However, women with favorable lipid levels, especially LDL/HDL cholesterol ratio <2.5, did not have increased risk of coronary heart disease with CEE with or without MPA irrespective of hs-CRP...
  70. ncbi request reprint Predictors of angina pectoris versus myocardial infarction from the Women's Health Initiative Observational Study
    Judith Hsia
    George Washington University, Washington, DC 20037, USA
    Am J Cardiol 93:673-8. 2004
    ..Thus, specific risk factors strongly and independently predicted whether women with an acute coronary syndrome would present with angina or with MI...
  71. pmc Serum 25-hydroxyvitamin D concentrations and risk for hip fractures
    Jane A Cauley
    University of Pittsburgh, Department of Epidemiology, 130 DeSoto Street, Crabtree A524, Pittsburgh, PA 15261, USA
    Ann Intern Med 149:242-50. 2008
    ..The relationship between serum 25-hydroxyvitamin D [25(OH) vitamin D] concentration and hip fractures is unclear...
  72. ncbi request reprint Calcium plus vitamin D supplementation and the risk of colorectal cancer
    Jean Wactawski-Wende
    Department of Social and Preventive Medicine, University at Buffalo, 270 Farber Hall, Buffalo, NY 14214, USA
    N Engl J Med 354:684-96. 2006
    ..However, randomized-trial evidence that calcium with vitamin D supplementation is beneficial in the primary prevention of colorectal cancer is lacking...
  73. ncbi request reprint Tissue plasminogen activator antigen and D-dimer as markers for atherothrombotic risk among healthy postmenopausal women
    Aruna D Pradhan
    Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Ave East, Boston, Mass 02215, USA
    Circulation 110:292-300. 2004
    ..Few studies have evaluated this relationship in women. In addition, although menopausal hormone therapy (HT) may alter markers of fibrinolytic function, the relevance of this effect for coronary risk assessment has not been studied...
  74. ncbi request reprint Effects of estrogen plus progestin on health-related quality of life
    Jennifer Hays
    Center for Women s Health, Department of Medicine, Baylor College of Medicine, Houston 77025, USA
    N Engl J Med 348:1839-54. 2003
    ..The Women's Health Initiative (WHI) and other clinical trials indicate that significant health risks are associated with combination hormone use. Less is known about the effect of hormone therapy on health-related quality of life...
  75. ncbi request reprint Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women's Health Initiative randomized trial
    Jane A Cauley
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA
    JAMA 290:1729-38. 2003
    ..In the Women's Health Initiative trial of estrogen-plus-progestin therapy, women assigned to active treatment had fewer fractures...
  76. ncbi request reprint Footwear style and risk of falls in older adults
    Thomas D Koepsell
    Department of Epidemiology, University of Washington, Seattle 98195, USA
    J Am Geriatr Soc 52:1495-501. 2004
    ..To determine how the risk of a fall in an older adult varies in relation to style of footwear worn...
  77. ncbi request reprint Effect of estrogen therapy on gallbladder disease
    Dominic J Cirillo
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, USA
    JAMA 293:330-9. 2005
    ..Estrogen therapy is thought to promote gallstone formation and cholecystitis but most data derive from observational studies rather than randomized trials...
  78. ncbi request reprint Walking compared with vigorous exercise for the prevention of cardiovascular events in women
    JoAnn E Manson
    Division of Preventive Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston 02215, USA
    N Engl J Med 347:716-25. 2002
    ..The role of walking, as compared with vigorous exercise, in the prevention of cardiovascular disease remains controversial. Data for women who are members of minority racial or ethnic groups are particularly sparse...
  79. ncbi request reprint Baseline associations between postmenopausal hormone therapy and inflammatory, haemostatic, and lipid biomarkers of coronary heart disease. The Women's Health Initiative Observational Study
    Robert D Langer
    Department of Family and Preventive Medicine, University of California, San Diego, 9500 Gilman Drive, MC 0978, La Jolla, CA 92093 0978, USA
    Thromb Haemost 93:1108-16. 2005
    ..Some associations differed between women with and without incident CHD, especially for EP, where inflammatory and thrombotic markers were higher in cases. These associations remain speculative pending confirmation in randomized trials...
  80. ncbi request reprint Postmenopausal hormone therapy and body composition--a substudy of the estrogen plus progestin trial of the Women's Health Initiative
    Zhao Chen
    Division of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ 85724, USA
    Am J Clin Nutr 82:651-6. 2005
    ..It has been suggested that hormone therapy may help counter undesirable changes in body composition in older women...
  81. ncbi request reprint Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial
    Jacques E Rossouw
    Division of Women s Health Initiative, National Heart, Lung, and Blood Institute, 6705 Rockledge Dr, One Rockledge Ctr, Suite 300, Bethesda, MD 20817
    JAMA 288:321-33. 2002
    ..Despite decades of accumulated observational evidence, the balance of risks and benefits for hormone use in healthy postmenopausal women remains uncertain...
  82. ncbi request reprint Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial
    Barbara V Howard
    MedStar Research Institute Howard University, Washington, DC, USA
    JAMA 295:655-66. 2006
    ..Multiple epidemiologic studies and some trials have linked diet with cardiovascular disease (CVD) prevention, but long-term intervention data are needed...
  83. ncbi request reprint Calcium plus vitamin D supplementation and the risk of fractures
    Rebecca D Jackson
    Division of Endocrinology, Ohio State University, 485 McCampbell, 1581 Dodd Dr, Columbus, OH 43210, USA
    N Engl J Med 354:669-83. 2006
    ..The efficacy of calcium with vitamin D supplementation for preventing hip and other fractures in healthy postmenopausal women remains equivocal...
  84. ncbi request reprint Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause
    Jacques E Rossouw
    Women s Health Initiative Branch, National Heart, Lung, and Blood Institute, Bethesda, MD 20892, USA
    JAMA 297:1465-77. 2007
    ..The timing of initiation of hormone therapy may influence its effect on cardiovascular disease...
  85. pmc Associations of serum sex hormone-binding globulin and sex hormone concentrations with hip fracture risk in postmenopausal women
    Jennifer S Lee
    Division of Endocrinology, Clinical Nutrition, and Vascular Medicine, Department of Internal Medicine, University of California Davis, Sacramento, CA 95817, USA
    J Clin Endocrinol Metab 93:1796-803. 2008
    ..Endogenous estradiol, testosterone, and SHBG may influence the risk of hip fracture...
  86. ncbi request reprint Validation of diagnoses of peptic ulcers and bleeding from administrative databases: a multi-health maintenance organization study
    Susan E Andrade
    Meyers Primary Care Institute Fallon Healthcare System and University of Massachusetts Medical School, Worcester, MA 01605, USA
    J Clin Epidemiol 55:310-3. 2002
    ..This study, using data from a large number of health plans located in different geographical regions, underscores the importance of evaluating the accuracy of the diagnoses from automated health plan databases...
  87. ncbi request reprint Gastric and duodenal safety of daily alendronate
    James G Donahue
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    Arch Intern Med 162:936-42. 2002
    ..This study was conducted to estimate the excess risk of hospitalizations for gastric or duodenal perforations, ulcers, and bleeding associated with alendronate use...
  88. ncbi request reprint Prehypertension and cardiovascular disease risk in the Women's Health Initiative
    Judith Hsia
    Department of Medicine, George Washington University, 2150 Pennsylvania Ave NW, Washington, DC 20037, USA
    Circulation 115:855-60. 2007
    ..Prehypertension is common and is associated with increased vascular mortality. The extent to which it increases risk of nonfatal myocardial infarction, stroke, and congestive heart failure is less clear...
  89. ncbi request reprint The Women's Health Initiative calcium-vitamin D trial: overview and baseline characteristics of participants
    Rebecca D Jackson
    College of Medicine and Public Health, Ohio State University, Columbus, OH, USA
    Ann Epidemiol 13:S98-106. 2003
  90. ncbi request reprint Validity of self-report for fractures among a multiethnic cohort of postmenopausal women: results from the Women's Health Initiative observational study and clinical trials
    Zhao Chen
    University of Arizona, Tucson, AZ, USA
    Menopause 11:264-74. 2004
    ..The purpose of this study is to examine the validity of, and factors associated with, the accuracy of self-report (participant-report and proxy-report) for fractures...
  91. ncbi request reprint Effect of low-dose thiazide diuretics on plasma lipids: results from a double-blind, randomized clinical trial in older men and women
    Susan M Ott
    University of Washington and Group Health Cooperative of Puget Sound, 1959 NE Pacific Street, Room BB 545, Seattle, WA 98195
    J Am Geriatr Soc 51:340-7. 2003
    ..To determine the effects of low doses of hydrochlorothiazide (HCTZ) on plasma lipids in healthy older men and women...
  92. ncbi request reprint Effects of conjugated equine estrogen on risk of fractures and BMD in postmenopausal women with hysterectomy: results from the women's health initiative randomized trial
    Rebecca D Jackson
    Division of Endocrinology, Diabetes, and Metabolism, The Ohio State University, Columbus, OH 43210, USA
    J Bone Miner Res 21:817-28. 2006
    ..The fracture reduction at the hip did not differ appreciably among risk strata. These data do not support overall benefit over risk, even in women at highest risk for fracture...
  93. ncbi request reprint Evaluation of decision rules to identify postmenopausal women for intervention related to osteoporosis
    Susan K Brenneman
    Outcomes Research and Management, Merck and Co, Inc, West Point, Pennsylvania 19486, USA
    Dis Manag 6:159-68. 2003
    ..The appropriate selection of a screening tool depends upon the objective for intervention and trade-off between not identifying women for BMD testing who are at high risk and identifying more women for BMD testing who are at low risk...
  94. ncbi request reprint Improvement in spine bone density and reduction in risk of vertebral fractures during treatment with antiresorptive drugs
    Steven R Cummings
    Department of Medicine, University of California, San Francisco, California, USA
    Am J Med 112:281-9. 2002
    ..To estimate how much the improvement in bone mass accounts for the reduction in risk of vertebral fracture that has been observed in randomized trials of antiresorptive treatments for osteoporosis...