Bruce A Knutson

Summary

Affiliation: Fred Hutchinson Cancer Research Center
Country: USA

Publications

  1. pmc Emergence and expansion of TFIIB-like factors in the plant kingdom
    Bruce A Knutson
    Fred Hutchinson Cancer Research Center, Division of Basic Sciences, 1100 Fairview Ave N, PO Box 19024, Mailstop A1 162, Seattle, WA 98109, USA Electronic address
    Gene 526:30-8. 2013
  2. pmc TFIIB-related factors in RNA polymerase I transcription
    Bruce A Knutson
    Fred Hutchinson Cancer Research Center, Division of Basic Sciences, 1100 Fairview Ave N, P O Box 19024, Mailstop A1 162, Seattle, WA 98109, USA
    Biochim Biophys Acta 1829:265-73. 2013
  3. pmc Insights into the domain and repeat architecture of target of rapamycin
    Bruce A Knutson
    Fred Hutchinson Cancer Research Center, Basic Sciences Division, 1100 Fairview Ave N, P O Box 19024, Mailstop A1 162, Seattle, WA 98109, USA
    J Struct Biol 170:354-63. 2010
  4. doi request reprint Expansion of poxvirus RNA polymerase subunits sharing homology with corresponding subunits of RNA polymerase II
    Bruce A Knutson
    Department of Biochemistry, Purdue University, West Lafayette, IN 47906, USA
    Virus Genes 36:307-11. 2008
  5. doi request reprint Downregulation of vaccinia virus intermediate and late promoters by host transcription factor YY1
    Bruce A Knutson
    Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA
    J Gen Virol 90:1592-9. 2009
  6. pmc Domains of Tra1 important for activator recruitment and transcription coactivator functions of SAGA and NuA4 complexes
    Bruce A Knutson
    Fred Hutchinson Cancer Research Center, Division of Basic Sciences, Seattle, WA 98109, USA
    Mol Cell Biol 31:818-31. 2011
  7. doi request reprint Bidirectional transcriptional promoters in the vaccinia virus genome
    Bruce A Knutson
    Department of Biochemistry, Purdue University, West Lafayatte, IN 47907, USA
    Virology 385:198-203. 2009
  8. pmc Vaccinia virus intermediate and late promoter elements are targeted by the TATA-binding protein
    Bruce A Knutson
    Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA
    J Virol 80:6784-93. 2006
  9. pmc Yeast Rrn7 and human TAF1B are TFIIB-related RNA polymerase I general transcription factors
    Bruce A Knutson
    Fred Hutchinson Cancer Research Center, Division of Basic Sciences, 1100 Fairview Avenue N, Post Office Box 19024, Mailstop A1 162, Seattle, WA 98109, USA
    Science 333:1637-40. 2011
  10. pmc Mechanism of Mediator recruitment by tandem Gcn4 activation domains and three Gal11 activator-binding domains
    Eric Herbig
    Fred Hutchinson Cancer Research Center, P O Box 19024, 1100 Fairview Ave N, Mailstop A1 162, Seattle, WA 98109, USA
    Mol Cell Biol 30:2376-90. 2010

Collaborators

Detail Information

Publications11

  1. pmc Emergence and expansion of TFIIB-like factors in the plant kingdom
    Bruce A Knutson
    Fred Hutchinson Cancer Research Center, Division of Basic Sciences, 1100 Fairview Ave N, PO Box 19024, Mailstop A1 162, Seattle, WA 98109, USA Electronic address
    Gene 526:30-8. 2013
    ..Together, these findings were used to generate a model for the evolutionary history of TFIIB-like proteins in eukaryotes. ..
  2. pmc TFIIB-related factors in RNA polymerase I transcription
    Bruce A Knutson
    Fred Hutchinson Cancer Research Center, Division of Basic Sciences, 1100 Fairview Ave N, P O Box 19024, Mailstop A1 162, Seattle, WA 98109, USA
    Biochim Biophys Acta 1829:265-73. 2013
    ..Models for Pol I transcription initiation are reexamined in light of these recent findings. This article is part of a Special Issue entitled: Transcription by Odd Pols...
  3. pmc Insights into the domain and repeat architecture of target of rapamycin
    Bruce A Knutson
    Fred Hutchinson Cancer Research Center, Basic Sciences Division, 1100 Fairview Ave N, P O Box 19024, Mailstop A1 162, Seattle, WA 98109, USA
    J Struct Biol 170:354-63. 2010
    ..These findings were used to assemble a 3D atomic model for the TOR protein...
  4. doi request reprint Expansion of poxvirus RNA polymerase subunits sharing homology with corresponding subunits of RNA polymerase II
    Bruce A Knutson
    Department of Biochemistry, Purdue University, West Lafayette, IN 47906, USA
    Virus Genes 36:307-11. 2008
    ..These results strengthen the concept that poxviral RNA polymerases likely evolved from cellular RNA polymerases...
  5. doi request reprint Downregulation of vaccinia virus intermediate and late promoters by host transcription factor YY1
    Bruce A Knutson
    Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA
    J Gen Virol 90:1592-9. 2009
    ..These results indicate that YY1 functions to negatively regulate these vaccinia virus promoters by binding to their initiator elements...
  6. pmc Domains of Tra1 important for activator recruitment and transcription coactivator functions of SAGA and NuA4 complexes
    Bruce A Knutson
    Fred Hutchinson Cancer Research Center, Division of Basic Sciences, Seattle, WA 98109, USA
    Mol Cell Biol 31:818-31. 2011
    ..Our results show that Tra1 recruitment at Gcn4-dependent and Rap1-dependent promoters requires the same regions of Tra1 and that separate regions of Tra1 contribute to the HAT activity and stability of the SAGA and NuA4 HAT modules...
  7. doi request reprint Bidirectional transcriptional promoters in the vaccinia virus genome
    Bruce A Knutson
    Department of Biochemistry, Purdue University, West Lafayatte, IN 47907, USA
    Virology 385:198-203. 2009
    ..Nucleotide replacements in the initiator element of a bidirectional promoter lead to activation of the other, suggesting that bidirectional promoter arrangement is a mechanism of attenuating promoter strength...
  8. pmc Vaccinia virus intermediate and late promoter elements are targeted by the TATA-binding protein
    Bruce A Knutson
    Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA
    J Virol 80:6784-93. 2006
    ....
  9. pmc Yeast Rrn7 and human TAF1B are TFIIB-related RNA polymerase I general transcription factors
    Bruce A Knutson
    Fred Hutchinson Cancer Research Center, Division of Basic Sciences, 1100 Fairview Avenue N, Post Office Box 19024, Mailstop A1 162, Seattle, WA 98109, USA
    Science 333:1637-40. 2011
    ..Our results point to the conservation of initiation mechanisms among multisubunit Pols and reveal a key function of yeast core factor/human SL1 in Pol I transcription...
  10. pmc Mechanism of Mediator recruitment by tandem Gcn4 activation domains and three Gal11 activator-binding domains
    Eric Herbig
    Fred Hutchinson Cancer Research Center, P O Box 19024, 1100 Fairview Ave N, Mailstop A1 162, Seattle, WA 98109, USA
    Mol Cell Biol 30:2376-90. 2010
    ..Our combined results show gene-specific coactivator requirements, a surprising redundancy in activator-target interactions, and an activator-coactivator interaction mediated by multiple low-affinity protein-protein interactions...
  11. pmc Antiviral activity of distamycin A against vaccinia virus is the result of inhibition of postreplicative mRNA synthesis
    Steven S Broyles
    Department of Biochemistry, Purdue University, West Lafayette, Indiana 47907 1153, USA
    J Virol 78:2137-41. 2004
    ....