Research TopicsGenomes and GenesSpecies | Shuo JiaoSummaryAffiliation: Fred Hutchinson Cancer Research Center Country: USA Publications
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Detail Information
Publications
Genome-wide search for gene-gene interactions in colorectal cancerShuo Jiao
Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
PLoS ONE 7:e52535. 2012..1) (nominal combined p = 2.51×10(-6); Bonferroni adjusted p = 0.03). Our study represents the first comprehensive search for GxG in CRC, and our results may provide new insight into the genetic etiology of CRC...
Probabilistic peak calling and controlling false discovery rate estimations in transcription factor binding site mapping from ChIP-seqShuo Jiao
Fred Hutchinson Cancer Institute, Seattle, WA, USA
Methods Mol Biol 674:161-77. 2010..s Quantitative Enrichment of Sequence Tags (QuEST) software tool. We demonstrate the prediction of the human growth-associated binding protein (GABPalpha) based on ChIP-seq observations...
The use of imputed values in the meta-analysis of genome-wide association studiesShuo Jiao
Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Genet Epidemiol 35:597-605. 2011..Our results show that the performance of the inverse variance weight is always indistinguishable from the optimal weight and similar to or better than the other two methods...
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysisUlrike Peters
Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Gastroenterology 144:799-807.e24. 2013..Heritable factors contribute to the development of colorectal cancer. Identifying the genetic loci associated with colorectal tumor formation could elucidate the mechanisms of pathogenesis...
Meta-analysis of new genome-wide association studies of colorectal cancer riskUlrike Peters
Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, USA
Hum Genet 131:217-34. 2012..03; combined p value 1.9 × 10(-4)). Our study suggests a complex nature of the contribution of common genetic variants to risk for colorectal cancer...
A pooled analysis of smoking and colorectal cancer: timing of exposure and interactions with environmental factorsJian Gong
Public Health Sciences Division, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109, USA
Cancer Epidemiol Biomarkers Prev 21:1974-85. 2012..What is unclear, however, is the impact of quitting smoking on risk attenuation and whether other risk factors for CRC modify this association...
Characterization of gene-environment interactions for colorectal cancer susceptibility lociCarolyn M Hutter
Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Cancer Res 72:2036-44. 2012....
A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) studyUlrike Peters
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
PLoS Genet 9:e1003171. 2013..Importantly our study demonstrated that comprehensive fine-mapping in AA provides a powerful approach to narrow in on the functional candidate(s) underlying the initial GWAS findings in European populations...
Powerful cocktail methods for detecting genome-wide gene-environment interactionLi Hsu
Biostatistics and Biomathematics Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Genet Epidemiol 36:183-94. 2012..It also allows for an easy incorporation of new methods as they are developed. Our work provides a comprehensive and powerful tool for devising effective strategies for genome-wide detection of gene-environment interactions...
