Yunda Huang

Summary

Affiliation: Fred Hutchinson Cancer Research Center
Country: USA

Publications

  1. pmc Comparing and combining data across multiple sources via integration of paired-sample data to correct for measurement error
    Yunda Huang
    Statistical Center for HIV AIDS Prevention and Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Stat Med 31:3748-59. 2012
  2. pmc Development of an automated analysis system for data from flow cytometric intracellular cytokine staining assays from clinical vaccine trials
    Nicholas Shulman
    LabKey Software Foundation, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Cytometry A 73:847-56. 2008
  3. pmc Extended follow-up confirms early vaccine-enhanced risk of HIV acquisition and demonstrates waning effect over time among participants in a randomized trial of recombinant adenovirus HIV vaccine (Step Study)
    Ann Duerr
    Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington 98109 1024, USA
    J Infect Dis 206:258-66. 2012
  4. pmc New clinical trial designs for HIV vaccine evaluation
    Zoe Moodie
    Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109, USA
    Curr Opin HIV AIDS 8:437-42. 2013
  5. pmc HIV-DNA priming alters T cell responses to HIV-adenovirus vaccine even when responses to DNA are undetectable
    Stephen C De Rosa
    Department of Laboratory Medicine, University of Washington, Seattle, WA 98195, USA
    J Immunol 187:3391-401. 2011
  6. pmc Impact of herpes simplex virus type 2 on HIV-1 acquisition and progression in an HIV vaccine trial (the Step study)
    Ruanne V Barnabas
    Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    J Acquir Immune Defic Syndr 57:238-44. 2011
  7. pmc Vaccine-induced HIV-specific CD8+ T cells utilize preferential HLA alleles and target-specific regions of HIV-1
    David Friedrich
    Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    J Acquir Immune Defic Syndr 58:248-52. 2011
  8. pmc Role of human immunodeficiency virus (HIV)-specific T-cell immunity in control of dual HIV-1 and HIV-2 infection
    Natalie N Zheng
    Department of Pathology, University of Washington, Seattle, WA 98195, USA
    J Virol 81:9061-71. 2007
  9. pmc Human adenovirus-specific T cells modulate HIV-specific T cell responses to an Ad5-vectored HIV-1 vaccine
    Nicole Frahm
    Vaccine and Infectious Disease Division and HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    J Clin Invest 122:359-67. 2012
  10. pmc Optimization and validation of an 8-color intracellular cytokine staining (ICS) assay to quantify antigen-specific T cells induced by vaccination
    Helen Horton
    Program in Infectious Diseases, Fred Hutchinson Cancer Research Center FHCRC, Seattle, WA 98109, USA
    J Immunol Methods 323:39-54. 2007

Collaborators

Detail Information

Publications10

  1. pmc Comparing and combining data across multiple sources via integration of paired-sample data to correct for measurement error
    Yunda Huang
    Statistical Center for HIV AIDS Prevention and Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Stat Med 31:3748-59. 2012
    ..We illustrate our methods using real enzyme-linked immunosorbent spot assay data generated by two HIV vaccine laboratories...
  2. pmc Development of an automated analysis system for data from flow cytometric intracellular cytokine staining assays from clinical vaccine trials
    Nicholas Shulman
    LabKey Software Foundation, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Cytometry A 73:847-56. 2008
    ..Routine use of the system does not require specialized expertise. This high-throughput analysis will provide great utility for rapid evaluation of complex multiparameter flow cytometric measurements collected from large clinical trials...
  3. pmc Extended follow-up confirms early vaccine-enhanced risk of HIV acquisition and demonstrates waning effect over time among participants in a randomized trial of recombinant adenovirus HIV vaccine (Step Study)
    Ann Duerr
    Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington 98109 1024, USA
    J Infect Dis 206:258-66. 2012
    ..97; P=1.0) over all follow-up time. Conclusions: The vaccine-associated risk seen in interim analysis was confirmed but waned with time from vaccination...
  4. pmc New clinical trial designs for HIV vaccine evaluation
    Zoe Moodie
    Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109, USA
    Curr Opin HIV AIDS 8:437-42. 2013
    ....
  5. pmc HIV-DNA priming alters T cell responses to HIV-adenovirus vaccine even when responses to DNA are undetectable
    Stephen C De Rosa
    Department of Laboratory Medicine, University of Washington, Seattle, WA 98195, USA
    J Immunol 187:3391-401. 2011
    ....
  6. pmc Impact of herpes simplex virus type 2 on HIV-1 acquisition and progression in an HIV vaccine trial (the Step study)
    Ruanne V Barnabas
    Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    J Acquir Immune Defic Syndr 57:238-44. 2011
    ..To explore these relationships, we examined the impact of preexisting HSV-2 infection in an international HIV vaccine trial...
  7. pmc Vaccine-induced HIV-specific CD8+ T cells utilize preferential HLA alleles and target-specific regions of HIV-1
    David Friedrich
    Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    J Acquir Immune Defic Syndr 58:248-52. 2011
    ..Thus, HLA immunodominance plays a substantial role in vaccine-induced T-cell responses...
  8. pmc Role of human immunodeficiency virus (HIV)-specific T-cell immunity in control of dual HIV-1 and HIV-2 infection
    Natalie N Zheng
    Department of Pathology, University of Washington, Seattle, WA 98195, USA
    J Virol 81:9061-71. 2007
    ..In conclusion, the T-cell memory responses associated with containment of single HIV-1 and HIV-2 infection play a similar significant role in the immune control of dual HIV-1 and HIV-2 infection...
  9. pmc Human adenovirus-specific T cells modulate HIV-specific T cell responses to an Ad5-vectored HIV-1 vaccine
    Nicole Frahm
    Vaccine and Infectious Disease Division and HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    J Clin Invest 122:359-67. 2012
    ..These findings provide what we believe to be a new understanding of how preexisting viral immunity may impact the efficacy of vaccines under current evaluation for prevention of HIV, tuberculosis, and malaria...
  10. pmc Optimization and validation of an 8-color intracellular cytokine staining (ICS) assay to quantify antigen-specific T cells induced by vaccination
    Helen Horton
    Program in Infectious Diseases, Fred Hutchinson Cancer Research Center FHCRC, Seattle, WA 98109, USA
    J Immunol Methods 323:39-54. 2007
    ..In conclusion, we provide the first description of a quantitatively validated ICS assay, which permits quantitative and qualitative evaluation of vaccine-induced immunogenicity and analysis of immune correlates of protection...