Sarah E Holte

Summary

Affiliation: Fred Hutchinson Cancer Research Center
Country: USA

Publications

  1. pmc Efficient use of longitudinal CD4 counts and viral load measures in survival analysis
    S E Holte
    Biostatistics and Biomathematics, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Stat Med 31:2086-97. 2012
  2. ncbi request reprint Density-dependent decay in HIV-1 dynamics
    Sarah E Holte
    Division of Public Health, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, PO Box 19024, Seattle, WA 98109, USA
    J Acquir Immune Defic Syndr 41:266-76. 2006
  3. pmc Evidence that low-level viremias during effective highly active antiretroviral therapy result from two processes: expression of archival virus and replication of virus
    Nicole H Tobin
    Department of Pediatrics, University of Washington, Seattle, WA, USA
    J Virol 79:9625-34. 2005
  4. pmc Human immunodeficiency viruses appear compartmentalized to the female genital tract in cross-sectional analyses but genital lineages do not persist over time
    Marta E Bull
    Department of Pediatrics University of Washington, Seattle, WA 98101, USA
    J Infect Dis 207:1206-15. 2013
  5. pmc Multiple viral genetic analyses detect low-level human immunodeficiency virus type 1 replication during effective highly active antiretroviral therapy
    Lisa M Frenkel
    Department of Pediatrics, University of Washington, Seattle, Washington, USA
    J Virol 77:5721-30. 2003
  6. ncbi request reprint Initiation of antiretroviral therapy leads to a rapid decline in cervical and vaginal HIV-1 shedding
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington, USA
    AIDS 21:501-7. 2007
  7. doi request reprint The effect of mental illness, substance use, and treatment for depression on the initiation of highly active antiretroviral therapy among HIV-infected individuals
    Mary K Tegger
    Department of Medicine, University of Washington, Seattle, Washington, USA
    AIDS Patient Care STDS 22:233-43. 2008
  8. pmc Post-prostatic massage fluid/urine as an alternative to semen for studying male genitourinary HIV-1 shedding
    Susan M Graham
    University of Washington, Box 359909, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
    Sex Transm Infect 87:232-7. 2011
  9. pmc Selection on the human immunodeficiency virus type 1 proteome following primary infection
    Yi Liu
    Department of Microbiology, University of Washington School of Medicine, Seattle, WA 98195 8070, USA
    J Virol 80:9519-29. 2006
  10. ncbi request reprint Sentinel surveillance of sexually transmitted infections/HIV and risk behaviors in vulnerable populations in 5 Central American countries
    Ramon J Soto
    World Vision International, Regional Office for Latin America and the Carribean, San Jose, Costa Rica
    J Acquir Immune Defic Syndr 46:101-11. 2007

Research Grants

Collaborators

Detail Information

Publications10

  1. pmc Efficient use of longitudinal CD4 counts and viral load measures in survival analysis
    S E Holte
    Biostatistics and Biomathematics, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Stat Med 31:2086-97. 2012
    ..Moreover, the FPC scores are shown to be a more powerful prognostic factor than other common summaries when used in survival analysis...
  2. ncbi request reprint Density-dependent decay in HIV-1 dynamics
    Sarah E Holte
    Division of Public Health, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, PO Box 19024, Seattle, WA 98109, USA
    J Acquir Immune Defic Syndr 41:266-76. 2006
    ..This suggests that conclusions about long-term viral dynamics of HIV infection based on simple exponential decay models should be carefully re-evaluated...
  3. pmc Evidence that low-level viremias during effective highly active antiretroviral therapy result from two processes: expression of archival virus and replication of virus
    Nicole H Tobin
    Department of Pediatrics, University of Washington, Seattle, WA, USA
    J Virol 79:9625-34. 2005
    ..These observations provide a plausible explanation for the divergent clinical outcomes previously associated with LLV...
  4. pmc Human immunodeficiency viruses appear compartmentalized to the female genital tract in cross-sectional analyses but genital lineages do not persist over time
    Marta E Bull
    Department of Pediatrics University of Washington, Seattle, WA 98101, USA
    J Infect Dis 207:1206-15. 2013
    ....
  5. pmc Multiple viral genetic analyses detect low-level human immunodeficiency virus type 1 replication during effective highly active antiretroviral therapy
    Lisa M Frenkel
    Department of Pediatrics, University of Washington, Seattle, Washington, USA
    J Virol 77:5721-30. 2003
    ..Furthermore, the decrease of cellular HIV-1 DNA to low absolute levels in those without genetic evidence of viral replication suggests that monitoring viral DNA during HAART may gauge low-level replication...
  6. ncbi request reprint Initiation of antiretroviral therapy leads to a rapid decline in cervical and vaginal HIV-1 shedding
    Susan M Graham
    Department of Medicine, University of Washington, Seattle, Washington, USA
    AIDS 21:501-7. 2007
    ..Antiretroviral therapy (ART) may decrease HIV-1 infectivity in women by reducing genital HIV-1 shedding...
  7. doi request reprint The effect of mental illness, substance use, and treatment for depression on the initiation of highly active antiretroviral therapy among HIV-infected individuals
    Mary K Tegger
    Department of Medicine, University of Washington, Seattle, Washington, USA
    AIDS Patient Care STDS 22:233-43. 2008
    ..Screening for these disorders in primary care settings and access to appropriate treatment are increasingly important components of providing care to HIV-infected patients...
  8. pmc Post-prostatic massage fluid/urine as an alternative to semen for studying male genitourinary HIV-1 shedding
    Susan M Graham
    University of Washington, Box 359909, 325 Ninth Avenue, Seattle, WA 98104 2499, USA
    Sex Transm Infect 87:232-7. 2011
    ..Because semen collection is often impractical, the acceptability, feasibility and validity of post-prostatic massage fluid/urine (post-PMF/U) was evaluated for studying male genitourinary HIV-1 shedding...
  9. pmc Selection on the human immunodeficiency virus type 1 proteome following primary infection
    Yi Liu
    Department of Microbiology, University of Washington School of Medicine, Seattle, WA 98195 8070, USA
    J Virol 80:9519-29. 2006
    ..Hence, a majority of the amino acids undergoing selection in this subject appeared to result from fitness-balanced CTL selection, confirming CTLs as a dominant selective force in HIV-1 infection...
  10. ncbi request reprint Sentinel surveillance of sexually transmitted infections/HIV and risk behaviors in vulnerable populations in 5 Central American countries
    Ramon J Soto
    World Vision International, Regional Office for Latin America and the Carribean, San Jose, Costa Rica
    J Acquir Immune Defic Syndr 46:101-11. 2007
    ..0, 95% confidence interval: 2.9 to 7.9). For these vulnerable populations, prevention must incorporate acceptable and effective sexual health services, including improved condom access and promotion...

Research Grants5

  1. Mathematical and Experimental Models for HIV Dynamics
    Sarah Holte; Fiscal Year: 2007
    ..Thus there is an urgent need to more accurately describe the decay profile of infected cell populations. ..