Carla Grandori

Summary

Affiliation: Fred Hutchinson Cancer Research Center
Country: USA

Publications

  1. Grandori C, Wu K, Fernandez P, Ngouenet C, Grim J, Clurman B, et al. Werner syndrome protein limits MYC-induced cellular senescence. Genes Dev. 2003;17:1569-74 pubmed
    ..We propose that WRN up-regulation by MYC may promote MYC-driven tumorigenesis by preventing cellular senescence. ..
  2. request reprint
    Grandori C, Gomez Roman N, Felton Edkins Z, Ngouenet C, Galloway D, Eisenman R, et al. c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I. Nat Cell Biol. 2005;7:311-8 pubmed
    ..We propose that stimulation of rRNA synthesis by c-Myc is a key pathway driving cell growth and tumorigenesis. ..

Detail Information

Publications2

  1. Grandori C, Wu K, Fernandez P, Ngouenet C, Grim J, Clurman B, et al. Werner syndrome protein limits MYC-induced cellular senescence. Genes Dev. 2003;17:1569-74 pubmed
    ..We propose that WRN up-regulation by MYC may promote MYC-driven tumorigenesis by preventing cellular senescence. ..
  2. request reprint
    Grandori C, Gomez Roman N, Felton Edkins Z, Ngouenet C, Galloway D, Eisenman R, et al. c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I. Nat Cell Biol. 2005;7:311-8 pubmed
    ..We propose that stimulation of rRNA synthesis by c-Myc is a key pathway driving cell growth and tumorigenesis. ..