Ann C Duerr

Summary

Affiliation: Fred Hutchinson Cancer Research Center
Country: USA

Publications

  1. ncbi request reprint Effect of HIV infection on atypical squamous cells of undetermined significance
    Ann Duerr
    Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Clin Infect Dis 42:855-61. 2006
  2. ncbi request reprint Viral load and CD4 count dynamics after HIV-1 seroconversion in homosexual and bisexual men in Rio de Janeiro, Brazil
    Gaston Djomand
    HIV Vaccine Trials Network, Seattle, WA, USA
    J Acquir Immune Defic Syndr 43:401-4. 2006
  3. ncbi request reprint Effect of contraceptive methods on natural history of HIV: studies from the Mombasa cohort
    Jared M Baeten
    University of Washington, Seattle, WA, USA
    J Acquir Immune Defic Syndr 38:S18-21. 2005
  4. ncbi request reprint HIV vaccines: new frontiers in vaccine development
    Ann Duerr
    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Clin Infect Dis 43:500-11. 2006
  5. ncbi request reprint HIV vaccine efficacy trials: towards the future of HIV prevention
    Denny Kim
    HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Infect Dis Clin North Am 21:201-17, x. 2007
  6. pmc The potential role of biomarkers in HIV preventive vaccine trials
    Ellen Maclachlan
    HIV Vaccine Trials Network HVTN, Fred Hutchinson Cancer Research Center FHCRC, Seattle, WA, USA
    J Acquir Immune Defic Syndr 51:536-45. 2009
  7. ncbi request reprint Abnormal vaginal cytology in HIV-infected and at-risk women after hysterectomy
    Pangaja Paramsothy
    Contraceptive Research and Development CONRAD Program, Arlington, VA, USA
    J Acquir Immune Defic Syndr 35:484-91. 2004
  8. ncbi request reprint Serum immunoglobulin G response to human papillomavirus type 16 virus-like particles in human immunodeficiency virus (HIV)-positive and risk-matched HIV-negative women
    Raphael P Viscidi
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Infect Dis 187:194-205. 2003
  9. ncbi request reprint Accuracy of Papanicolaou test among HIV-infected women
    Jean R Anderson
    Department of Gynecology and Obstetrics, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Clin Infect Dis 42:562-8. 2006
  10. ncbi request reprint Outcomes after treatment of cervical intraepithelial neoplasia among women with HIV
    L Stewart Massad
    Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, IL 62794 9640, USA
    J Low Genit Tract Dis 11:90-7. 2007

Collaborators

Detail Information

Publications43

  1. ncbi request reprint Effect of HIV infection on atypical squamous cells of undetermined significance
    Ann Duerr
    Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Clin Infect Dis 42:855-61. 2006
    ..Detection of atypical squamous cells of undetermined significance (ASCUS) is a cervical cytologic finding that is suggestive but not definitive of squamous intraepithelial lesions (SILs)...
  2. ncbi request reprint Viral load and CD4 count dynamics after HIV-1 seroconversion in homosexual and bisexual men in Rio de Janeiro, Brazil
    Gaston Djomand
    HIV Vaccine Trials Network, Seattle, WA, USA
    J Acquir Immune Defic Syndr 43:401-4. 2006
    ..Reliable predictors of HIV disease progression are scarce in developing countries, where most HIV infections occur. We describe early virologic and immunologic events among men who have sex with men in Rio de Janeiro, Brazil...
  3. ncbi request reprint Effect of contraceptive methods on natural history of HIV: studies from the Mombasa cohort
    Jared M Baeten
    University of Washington, Seattle, WA, USA
    J Acquir Immune Defic Syndr 38:S18-21. 2005
  4. ncbi request reprint HIV vaccines: new frontiers in vaccine development
    Ann Duerr
    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Clin Infect Dis 43:500-11. 2006
    ..The most immunogenic of these products appear to be the recombinant adenovirus vector vaccines, 2 of which are now in advanced clinical development...
  5. ncbi request reprint HIV vaccine efficacy trials: towards the future of HIV prevention
    Denny Kim
    HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Infect Dis Clin North Am 21:201-17, x. 2007
    ..Adenovirus vector-based regimens that induce CTLs are currently in efficacy trial testing. These efficacy trials are using surrogate end points in an innovative Phase 2B trial design...
  6. pmc The potential role of biomarkers in HIV preventive vaccine trials
    Ellen Maclachlan
    HIV Vaccine Trials Network HVTN, Fred Hutchinson Cancer Research Center FHCRC, Seattle, WA, USA
    J Acquir Immune Defic Syndr 51:536-45. 2009
    ..Although not invariably useful and bringing their own cost in terms of measurement and validation, a variety of biomarkers may aid at each stage of trial conduct...
  7. ncbi request reprint Abnormal vaginal cytology in HIV-infected and at-risk women after hysterectomy
    Pangaja Paramsothy
    Contraceptive Research and Development CONRAD Program, Arlington, VA, USA
    J Acquir Immune Defic Syndr 35:484-91. 2004
    ..To determine the frequency of and risk factors for abnormal vaginal Papanicolaou smears in HIV-infected women after hysterectomy...
  8. ncbi request reprint Serum immunoglobulin G response to human papillomavirus type 16 virus-like particles in human immunodeficiency virus (HIV)-positive and risk-matched HIV-negative women
    Raphael P Viscidi
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Infect Dis 187:194-205. 2003
    ..Despite the higher prevalence of HPV infection in this group, most HIV-positive women are able to control HPV-16 replication at the cervix, and reactivation, if it occurs, is not very common...
  9. ncbi request reprint Accuracy of Papanicolaou test among HIV-infected women
    Jean R Anderson
    Department of Gynecology and Obstetrics, Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Clin Infect Dis 42:562-8. 2006
    ..We examined the accuracy of the Papanicolaou (Pap) test among women with and women at high risk for human immunodeficiency virus (HIV) infection...
  10. ncbi request reprint Outcomes after treatment of cervical intraepithelial neoplasia among women with HIV
    L Stewart Massad
    Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, IL 62794 9640, USA
    J Low Genit Tract Dis 11:90-7. 2007
    ..To describe outcomes after treatment of cervical intraepithelial neoplasia (CIN) in women with HIV...
  11. ncbi request reprint HIV-discordant couples and parenthood: how are we dealing with the risk of transmission?
    Pietro L Vernazza
    AIDS 20:635-6. 2006
  12. ncbi request reprint Reasons for testing and clinical and demographic profile of adolescents with non-perinatally acquired HIV infection
    Althea M Grant
    Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Pediatrics 117:e468-75. 2006
    ....
  13. doi request reprint Safe conception for HIV discordant couples through sperm-washing: experience and perceptions of patients in Milan, Italy
    Saswati Sunderam
    Social Scientist and Statistician, Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta GA, USA
    Reprod Health Matters 16:211-9. 2008
    ..They perceived assisted conception services to be a safe and effective alternative to spontaneous conception, and felt that society has a moral obligation to provide such services...
  14. ncbi request reprint Time to clearance of human papillomavirus infection by type and human immunodeficiency virus serostatus
    Jill E Koshiol
    Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA
    Int J Cancer 119:1623-9. 2006
    ..57 (95% CI: 0.22-1.45) for HIV-positive and -negative women, respectively. HPV types within the high-risk category had low estimated clearance rates relative to low-risk types, but HRs were not substantially modified by HIV serostatus...
  15. ncbi request reprint Vulvar, vaginal, and perianal intraepithelial neoplasia in women with or at risk for human immunodeficiency virus
    Denise J Jamieson
    Womens Health and Fertility Branch, Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Obstet Gynecol 107:1023-8. 2006
    ..To compare the incidence of vulvar, vaginal, and perianal intraepithelial neoplasia among human immunodeficiency virus (HIV)-infected women with a group of well-matched high-risk HIV-uninfected controls...
  16. ncbi request reprint Smoking and time to clearance of human papillomavirus infection in HIV-seropositive and HIV-seronegative women
    Jill Koshiol
    Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, USA
    Am J Epidemiol 164:176-83. 2006
    ..93, 95% CI: 0.68, 1.26) women. HPV clearance did not appear to vary by amount or duration of smoking. Smoking did not modify overall clearance but was associated with lower high-risk HPV clearance in HIV-seronegative women...
  17. doi request reprint Survival of blood donors and their spouses with HIV-1 subtype E (CRF01 A_E) infection in northern Thailand, 1992-2007
    Kenrad E Nelson
    Department of Epidemiology, Johns Hopkins University, Bloomberg School of PublicHealth, 615N Wolfe Street, Baltimore, Maryland 21205, USA
    AIDS 21:S47-54. 2007
    ..To evaluate the survival patterns among adults in Thailand 8-14 years after HIV-1 subtype E (CRF01 A_E) infection...
  18. ncbi request reprint Nutritional biomarkers associated with gynecological conditions among US women with or at risk of HIV infection
    Beth C Tohill
    Centers for Disease Control and Prevention, National Center for Chronic Disease and Public Health Prevention, Division of Nutrition and Physical Activity and Division of Reproductive Health, Atlanta, GA 30341, USA
    Am J Clin Nutr 85:1327-34. 2007
    ..This relation among HIV, nutrition, and gynecological conditions is complex and has rarely been investigated...
  19. pmc Involving communities in the design of clinical trial protocols: the BAN Study in Lilongwe, Malawi
    Amy L Corneli
    University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Contemp Clin Trials 28:59-67. 2007
    ....
  20. ncbi request reprint Coreceptor utilization of HIV type 1 subtype E viral isolates from Thai men with HIV type 1-infected and uninfected wives
    Utaiwan Utaipat
    HIV Immunology and Diagnostics Branch, DASTLR, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    AIDS Res Hum Retroviruses 18:1-11. 2002
    ..Thus, there was no association between the pattern of coreceptor usage and transmissibility among these subtype E HIV-1 isolates...
  21. pmc Endpoints and regulatory issues in HIV vaccine clinical trials: lessons from a workshop
    Dean Follmann
    National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA
    J Acquir Immune Defic Syndr 44:49-60. 2007
    ..Use of acquisition and a postinfection surrogate as coprimary endpoints was supported, along with use of composite endpoints and exploration of heterogeneity in vaccine efficacy by characteristics of the host and virus...
  22. ncbi request reprint Reproductive options for HIV-serodiscordant couples
    Pablo Barreiro
    Department of Infectious Diseases, Hospital Carlos III, Madrid, Spain
    AIDS Rev 8:158-70. 2006
    ..This review discusses the pros and cons of reproductive options in HIV-infected persons and proposes a protocol for their counseling...
  23. ncbi request reprint T-lymphocyte profile and total and virus-specific immunoglobulin concentrations in the cervix of HIV-1-infected women
    Alison J Quayle
    Department of Immunology, Microbiology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA, USA
    J Acquir Immune Defic Syndr 44:292-8. 2007
    ..The mucosal lymphocyte population is the largest in the body, and the gastrointestinal compartment has been well characterized in HIV infection. Much less is known about the effects of HIV on the genital tract...
  24. ncbi request reprint Breast milk CD4+ T cells express high levels of C chemokine receptor 5 and CXC chemokine receptor 4 and are preserved in HIV-infected mothers receiving highly active antiretroviral therapy
    Athena P Kourtis
    Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    J Infect Dis 195:965-72. 2007
    ..Little characterization of breast milk CD4(+) T lymphocytes has been done so far...
  25. ncbi request reprint Integrating family planning and prevention of mother-to-child HIV transmission in resource-limited settings
    Ann Duerr
    Centers for Disease Control and Prevention, Atlanta, GA, USA
    Lancet 366:261-3. 2005
  26. ncbi request reprint Male viral load and heterosexual transmission of HIV-1 subtype E in northern Thailand
    Sodsai Tovanabutra
    Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand
    J Acquir Immune Defic Syndr 29:275-83. 2002
    ....
  27. ncbi request reprint The impact of HIV infection and immunodeficiency on human papillomavirus type 6 or 11 infection and on genital warts
    Michael J Silverberg
    Johns Hopkins School of Public Health, Baltimore, Maryland 21205, USA
    Sex Transm Dis 29:427-35. 2002
    ..HIV infection and associated immunodeficiency are known to alter the course of human papillomavirus (HPV) infections and of associated diseases...
  28. ncbi request reprint Human immunodeficiency virus (HIV)-specific antibody in cervicovaginal lavage specimens obtained from women infected with HIV type 1
    Selvi B Williams
    Department of Medicine, Brown University School of Medicine, Providence, RI 02906, USA
    Clin Infect Dis 35:611-7. 2002
    ..0474) compared with women who did not have bacterial vaginosis. Enhanced understanding of correlates of mucosal immunity to HIV-1 may assist in the design of vaccine strategies or in the prevention of vertical transmission of HIV-1...
  29. ncbi request reprint Incident and persistent vulvovaginal candidiasis among human immunodeficiency virus-infected women: Risk factors and severity
    Ann Duerr
    National Center for Chronic Disease Prevention and Health Promotion, Division of Reproductive Health HIV Section, Centers for Disease Control and Prevention, Mailstop K 34, 4770 Buford Highway NE, Atlanta, GA 30341 3717, USA
    Obstet Gynecol 101:548-56. 2003
    ..To examine risk factors for vulvovaginal candidiasis among women with or at risk for human immunodeficiency virus (HIV) infection...
  30. ncbi request reprint Broad human immunodeficiency virus (HIV)-specific T cell responses to conserved HIV proteins in HIV-seronegative women highly exposed to a single HIV-infected partner
    Nattawan Promadej
    Centers for Disease Control and Prevention, Emory University, Atlanta, Georgia, USA
    J Infect Dis 187:1053-63. 2003
    ..Remarkably, however, long-lived HIV-specific T cells were detected in 2 HW who had an extended period (>3.9 years) of no HIV exposure. These findings have important implications for HIV vaccine design...
  31. ncbi request reprint Longitudinal study of mucosal Candida species colonization and candidiasis among human immunodeficiency virus (HIV)-seropositive and at-risk HIV-seronegative women
    Suzanne E Ohmit
    Wayne State University School of Medicine, Detroit, Michigan, USA
    J Infect Dis 188:118-27. 2003
    ..In HIV-seropositive women, mucosal candidiasis is the consequence of multiple interacting factors...
  32. ncbi request reprint Longitudinal study of cervical squamous intraepithelial lesions in human immunodeficiency virus (HIV)-seropositive and at-risk HIV-seronegative women
    Paula Schuman
    Wayne State University School of Medicine, Detroit, Michigan 48109, USA
    J Infect Dis 188:128-36. 2003
    ..SIL regression was less likely among HIV-seropositive women with higher HIV loads. No beneficial effect of highly active antiretroviral therapy was demonstrated...
  33. ncbi request reprint Assisted reproductive technologies for HIV-discordant couples
    Ann Duerr
    Centers for Disease Control and Prevention
    Am J Bioeth 3:45-7. 2003
  34. ncbi request reprint Human papillomavirus type 16 and immune status in human immunodeficiency virus-seropositive women
    Howard D Strickler
    Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Natl Cancer Inst 95:1062-71. 2003
    ..To address this issue, we examined HPV test results from repeated study visits in the WIHS and from an independent study, the HIV Epidemiology Research Study (HERS)...
  35. ncbi request reprint Prevention of perinatal HIV transmission: a review of novel strategies
    Athena P Kourtis
    Eastern Virginia Medical School, Norfolk, USA
    Expert Opin Investig Drugs 12:1535-44. 2003
    ....
  36. ncbi request reprint Breast milk and HIV-1: vector of transmission or vehicle of protection?
    Athena P Kourtis
    Eastern Virginia Medical School, Norfolk, VA, USA
    Lancet Infect Dis 3:786-93. 2003
    ....
  37. ncbi request reprint Implications of blood contamination for assessment of local cellular immunity in the endocervix
    Alison J Quayle
    Department of Immunology, Microbiology and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA
    AIDS Res Hum Retroviruses 20:543-6. 2004
    ....
  38. ncbi request reprint Lymphocyte homeostasis in HIV-infected northern Thais
    Doungnapa Kingkeow
    Research Institute for Health Sciences, Chiang Mai University, Thailand
    AIDS Res Hum Retroviruses 20:636-41. 2004
    ..2%, -12.0%) annually from 4.5 to 2 years prior to death and 63.7% (-72.3%, -53.6%) annually over the remaining 2 years. Similar lymphocyte patterns have been reported in U. S. and European populations with HIV-1 subtype B infection...
  39. ncbi request reprint Seroprevalence of human herpesvirus 8 infection in Northern Thailand
    Nora Chen
    Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Clin Infect Dis 39:1052-8. 2004
    ..2% of reported patients with AIDS in Thailand had KS), we determined the HHV-8 seroprevalence among populations who were HIV positive or at risk of HIV infection...
  40. pmc Vaginal flora morphotypic profiles and assessment of bacterial vaginosis in women at risk for HIV infection
    Beth C Tohill
    Centers for Disease Control and Prevention, National Center for Chronic Disease and Public Health Prevention, Division of Nutrition and Physical Activity, Atlanta, GA 30341, USA
    Infect Dis Obstet Gynecol 12:121-6. 2004
    ..The proposed profiles from the Gram stain reflect the morphotypic categories describing vaginal flora that may enable clearer elucidation of gynecologic and obstetric outcomes in various populations...
  41. ncbi request reprint Predictors of low CD4 count in resource-limited settings: based on an antiretroviral-naive heterosexual thai population
    Caroline Costello
    Centers for Disease Control and Prevention, Atlanta, GA, USA
    J Acquir Immune Defic Syndr 39:242-8. 2005
    ..0% in men, 68.2% in women) with less than a 6% decrease in specificity...
  42. ncbi request reprint Do women with HIV infection have different indications for hysterectomy?
    Pangaja Paramsothy
    J Acquir Immune Defic Syndr 39:378-9. 2005
  43. ncbi request reprint Characterization of genital human papillomavirus infection in women who have or who are at risk of having HIV infection
    Denise J Jamieson
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Am J Obstet Gynecol 186:21-7. 2002
    ....

Research Grants4

  1. Immunization of Oral Mucosa for Induction of Rectal and Genital Mucosal Immunity
    Ann Duerr; Fiscal Year: 2009
    ..It will also investigate the usefulness of this route of immunization for protection against respiratory pathogens, such as influenza, when immunity in the nose and lungs is desired. ..
  2. Immunization of Oral Mucosa for Induction of Rectal and Genital Mucosal Immunity
    Ann C Duerr; Fiscal Year: 2010
    ..It will also investigate the usefulness of this route of immunization for protection against respiratory pathogens, such as influenza, when immunity in the nose and lungs is desired. ..
  3. Immunization of Oral Mucosa for Induction of Rectal and Genital Mucosal Immunity
    Ann Duerr; Fiscal Year: 2009
    ..It will also investigate the usefulness of this route of immunization for protection against respiratory pathogens, such as influenza, when immunity in the nose and lungs is desired. ..