Jennifer A Doherty

Summary

Affiliation: Fred Hutchinson Cancer Research Center
Country: USA

Publications

  1. ncbi request reprint Dose of progestin in postmenopausal-combined hormone therapy and risk of endometrial cancer
    Susan D Reed
    Department of Obstetrics and Gynecology, Division of Public Health Sciences, University of Washington, 325 9th Avenue, Seattle, WA 98115, USA
    Am J Obstet Gynecol 191:1146-51. 2004
  2. ncbi request reprint Long-term use of postmenopausal estrogen and progestin hormone therapies and the risk of endometrial cancer
    Jennifer A Doherty
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Am J Obstet Gynecol 197:139.e1-7. 2007
  3. pmc Recent alcohol consumption and risk of incident ovarian carcinoma: a pooled analysis of 5,342 cases and 10,358 controls from the Ovarian Cancer Association Consortium
    Linda E Kelemen
    Department of Population Health Research, Alberta Health Services Cancer Care, AB, Canada
    BMC Cancer 13:28. 2013
  4. pmc ESR1/SYNE1 polymorphism and invasive epithelial ovarian cancer risk: an Ovarian Cancer Association Consortium study
    Jennifer A Doherty
    Program in Epidemiology M4 C308, Fred Hutchinson Cancer Research Center, PO Box 19024, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 19:245-50. 2010
  5. pmc Selected estrogen receptor 1 and androgen receptor gene polymorphisms in relation to risk of breast cancer and fibrocystic breast conditions among Chinese women
    Lori C Sakoda
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Cancer Epidemiol 35:48-55. 2011
  6. pmc Polymorphisms in steroid hormone biosynthesis genes and risk of breast cancer and fibrocystic breast conditions in Chinese women
    Lori C Sakoda
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 17:1066-73. 2008
  7. ncbi request reprint Diabetes and endometrial cancer: an evaluation of the modifying effects of other known risk factors
    Babette S Saltzman
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Am J Epidemiol 167:607-14. 2008
  8. pmc Genetic variation in CYP19A1 and risk of breast cancer and fibrocystic breast conditions among women in Shanghai, China
    Chu Chen
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Mailstop M5 C800, P O Box 19024, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 17:3457-66. 2008
  9. ncbi request reprint Endometrial cancer risk in estrogen users after switching to estrogen-progestin therapy
    Jessica Chubak
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98195, USA
    Cancer Causes Control 18:1001-7. 2007
  10. pmc Pregnancy history and risk of endometrial cancer
    Gaia Pocobelli
    Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98195, USA
    Epidemiology 22:638-45. 2011

Detail Information

Publications28

  1. ncbi request reprint Dose of progestin in postmenopausal-combined hormone therapy and risk of endometrial cancer
    Susan D Reed
    Department of Obstetrics and Gynecology, Division of Public Health Sciences, University of Washington, 325 9th Avenue, Seattle, WA 98115, USA
    Am J Obstet Gynecol 191:1146-51. 2004
    ..The pattern and number of days per month that progestin is given in postmenopausal combined hormone therapy appears to affect endometrial cancer risk. We assessed the impact of progestin dose on this risk...
  2. ncbi request reprint Long-term use of postmenopausal estrogen and progestin hormone therapies and the risk of endometrial cancer
    Jennifer A Doherty
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Am J Obstet Gynecol 197:139.e1-7. 2007
    ....
  3. pmc Recent alcohol consumption and risk of incident ovarian carcinoma: a pooled analysis of 5,342 cases and 10,358 controls from the Ovarian Cancer Association Consortium
    Linda E Kelemen
    Department of Population Health Research, Alberta Health Services Cancer Care, AB, Canada
    BMC Cancer 13:28. 2013
    ..Because OC and ovarian borderline tumor histologic types differ genetically, molecularly and clinically, large numbers are needed to estimate risk associations...
  4. pmc ESR1/SYNE1 polymorphism and invasive epithelial ovarian cancer risk: an Ovarian Cancer Association Consortium study
    Jennifer A Doherty
    Program in Epidemiology M4 C308, Fred Hutchinson Cancer Research Center, PO Box 19024, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 19:245-50. 2010
    ..These data provide suggestive evidence that the rs2295190 T allele, or another allele in linkage disequilibrium with it, may be associated with increased risk of invasive ovarian cancer...
  5. pmc Selected estrogen receptor 1 and androgen receptor gene polymorphisms in relation to risk of breast cancer and fibrocystic breast conditions among Chinese women
    Lori C Sakoda
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Cancer Epidemiol 35:48-55. 2011
    ..Polymorphisms in sex hormone receptor-encoding genes may alter the activity of sex hormone receptors and thereby affect susceptibility to breast cancer and related outcomes...
  6. pmc Polymorphisms in steroid hormone biosynthesis genes and risk of breast cancer and fibrocystic breast conditions in Chinese women
    Lori C Sakoda
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 17:1066-73. 2008
    ..Our findings support the possibility that common allelic variation at the CYP11A1 D15S520 locus alters breast cancer risk in Chinese women...
  7. ncbi request reprint Diabetes and endometrial cancer: an evaluation of the modifying effects of other known risk factors
    Babette S Saltzman
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Am J Epidemiol 167:607-14. 2008
    ..These results support the hypothesis that type 2 diabetes is associated with endometrial cancer irrespective of the presence of other risk factors for this disease, except possibly hypertension and extreme obesity...
  8. pmc Genetic variation in CYP19A1 and risk of breast cancer and fibrocystic breast conditions among women in Shanghai, China
    Chu Chen
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Mailstop M5 C800, P O Box 19024, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 17:3457-66. 2008
    ..Our findings suggest that CYP19A1 variation may enhance breast cancer development in some women, but further confirmation is warranted...
  9. ncbi request reprint Endometrial cancer risk in estrogen users after switching to estrogen-progestin therapy
    Jessica Chubak
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98195, USA
    Cancer Causes Control 18:1001-7. 2007
    ..It is unknown whether postmenopausal unopposed estrogen users are better off, in terms of endometrial cancer risk, switching to a combined estrogen-progestin regimen or stopping hormone use altogether...
  10. pmc Pregnancy history and risk of endometrial cancer
    Gaia Pocobelli
    Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98195, USA
    Epidemiology 22:638-45. 2011
    ..Less clear is whether timing of pregnancies during reproductive life influences risk, and the degree to which incomplete pregnancies are associated with a reduced risk...
  11. pmc Long-term use of continuous-combined estrogen-progestin hormone therapy and risk of endometrial cancer
    Amanda I Phipps
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, Seattle, WA 98109, USA
    Cancer Causes Control 22:1639-46. 2011
    ..19, 95% CI: 0.05-0.68). Associations did not differ according to recency of use. These results suggest that long duration of use of continuous-combined estrogen-progestin therapy is associated with a reduced risk of endometrial cancer...
  12. ncbi request reprint Risk factors for the incidence of endometrial cancer according to the aggressiveness of disease
    Jocelyn M Weiss
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Am J Epidemiol 164:56-62. 2006
    ..In general, a woman's risk of endometrial cancer appears to be influenced by similar risk factors regardless of disease severity...
  13. pmc Polymorphisms in nucleotide excision repair genes and endometrial cancer risk
    Jennifer A Doherty
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Cancer Epidemiol Biomarkers Prev 20:1873-82. 2011
    ..Certain estrogen metabolites can form bulky DNA adducts, which are removed via nucleotide excision repair (NER), and the ability to carry out this repair might be related to endometrial cancer risk...
  14. pmc Glutathione S-transferase M1 and P1 polymorphisms and risk of breast cancer and fibrocystic breast conditions in Chinese women
    Lori C Sakoda
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Department of Epidemiology, University of Washington, Mailstop M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
    Breast Cancer Res Treat 109:143-55. 2008
    ..The observed increased risk of breast cancer associated with joint carriage of the GSTM1 null genotype and GSTP1 105-Val allele needs confirmation in other studies...
  15. ncbi request reprint Nucleotide excision repair genotype and the incidence of endometrial cancer: effect of other risk factors on the association
    Jocelyn M Weiss
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA, USA
    Gynecol Oncol 103:891-6. 2006
    ..Certain nucleotide excision repair (NER) genotypes appear to be associated with an altered risk of endometrial cancer. These associations could be modified by characteristics and exposures that themselves influence risk of disease...
  16. pmc Risk of epithelial ovarian cancer in relation to benign ovarian conditions and ovarian surgery
    Mary Anne Rossing
    Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA 98108 1024, USA
    Cancer Causes Control 19:1357-64. 2008
    ..We assessed the risk associated with a prior diagnosis of, and ovarian surgery following, ovarian cysts and endometriosis, with a focus on characterizing risk among tumor subgroups...
  17. pmc Recreational physical activity and risk of epithelial ovarian cancer
    Mary Anne Rossing
    Program in Epidemiology, Fred Hutchinson Cancer Research Center, PO Box 19024, Seattle, WA 98108 1024, USA
    Cancer Causes Control 21:485-91. 2010
    ..In a population-based case-control study of epithelial ovarian cancer, we assessed risk associated with recreational physical activity with a focus on characterizing risk within histologic subtypes...
  18. doi request reprint Aspirin, nonaspirin nonsteroidal anti-inflammatory drug, and acetaminophen use and risk of invasive epithelial ovarian cancer: a pooled analysis in the Ovarian Cancer Association Consortium
    Britton Trabert
    Affiliations of authors Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD BT, Lab, NW University of Texas School of Public Health, Houston, TX RBN Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA WL Channing Division of Network Medicine MAM, EMP and Obstetrics and Gynecology Epidemiology Center DWC, KLT, Brigham and Women s Hospital and Harvard Medical School, Boston, MA Department of Epidemiology, Harvard School of Public Health, Boston, MA MAM, EMP, DWC, KLT Department of Health Sciences Research, Division of Epidemiology, Mayo Clinic, Rochester, MN ELG Queensland Institute of Medical Research, Brisbane, Australia PMW, CMN, SJJ, Australian Ovarian Cancer Study Group, the Australian Cancer Study Ovarian Cancer Peter MacCallum Cancer Centre, East Melbourne, Australia Australian Ovarian Cancer Study Group Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT HAR Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA MAR, Brazil
    J Natl Cancer Inst 106:djt431. 2014
    ..Epidemiologic studies analyzing aspirin, nonaspirin nonsteroidal anti-inflammatory drug (NSAID), and acetaminophen use and ovarian cancer risk have been inconclusive...
  19. pmc Nightshift work and risk of ovarian cancer
    Parveen Bhatti
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Occup Environ Med 70:231-7. 2013
    ..We evaluated the association between self-reported nightshift work, a known circadian disruptor, and ovarian cancer in a population-based case-control study...
  20. pmc Use of nonsteroidal antiinflammatory drugs and risk of endometrial cancer
    Clara Bodelon
    Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98195 7236, USA
    Am J Epidemiol 170:1512-7. 2009
    ..73, 1.53). NSAID use was unrelated to risk of endometrial cancer in both obese and nonobese women. Results from this study suggest that the use of aspirin or other NSAIDs has little or no influence on the risk of endometrial cancer...
  21. pmc Chromosome 15q24-25.1 variants, diet, and lung cancer susceptibility in cigarette smokers
    Lori C Sakoda
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, PO Box 19024, Mailstop M4 C308, Seattle, WA 98109 1024, USA
    Cancer Causes Control 22:449-61. 2011
    ..Studying gene-environment interactions may provide insight about mechanisms underpinning the reported association between chromosome 15q24-25.1 variation and lung cancer susceptibility...
  22. ncbi request reprint Menopausal hormone therapy and risk of epithelial ovarian cancer
    Mary Anne Rossing
    Program in Epidemiology, Fred Hutchinson Cancer Research Center, P O Box 19024, Seattle, WA 98108 1024, USA
    Cancer Epidemiol Biomarkers Prev 16:2548-56. 2007
    ..These findings, if replicated, may have implications both for public health and development of chemoprevention strategies...
  23. ncbi request reprint Genetic factors in catechol estrogen metabolism in relation to the risk of endometrial cancer
    Jennifer A Doherty
    Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, P O Box 19024 M4 C308, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 14:357-66. 2005
    ....
  24. pmc Characteristics related to the maternal intrauterine environment and risk of epithelial ovarian cancer
    Mary Anne Rossing
    Program in Epidemiology, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington 98108 1024, USA
    Ann Epidemiol 18:411-5. 2008
    ..In a population-based study of 812 women ages 35-74 years with epithelial ovarian cancer diagnosed in Washington State from 2002 to 2005 and 1313 controls, we assessed the relation of such factors to disease risk...
  25. pmc Sun exposure and risk of epithelial ovarian cancer
    Clara Bodelon
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Cancer Causes Control 23:1985-94. 2012
    ..Furthermore, studies have not investigated whether sun exposure at different periods in the lifetime of a person results in differences in risk associations, and little is known about differences according to histological subtype...
  26. pmc Biomarkers of progestin therapy resistance and endometrial hyperplasia progression
    Kristen Upson
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Am J Obstet Gynecol 207:36.e1-8. 2012
    ..We sought to identify biomarkers associated with progestin therapy resistance and persistence/progression of endometrial hyperplasia...
  27. ncbi request reprint Insulin-like growth factor-I, insulin-like growth factor binding protein-3 and the risk of fibrocystic breast conditions among Chinese women
    Chu Chen
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Int J Cancer 118:2303-9. 2006
    ..13 (1.50-6.53), 4.57 (2.22-9.39) and 6.30 (3.08-12.89), compared with the lowest fourth. Our results suggest that elevated levels of IGF-I may contribute to the development of FBC...
  28. ncbi request reprint Interindividual variation in nucleotide excision repair genes and risk of endometrial cancer
    Jocelyn M Weiss
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Occupational and Environmental Epidemiology Branch, 6120 Executive Boulevard, EPS 8123, MSC 7240, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 14:2524-30. 2005
    ..58; 95% CI, 0.35-0.96). Our data suggest that interindividual variation in XPA and XPC influences a woman's risk of endometrial cancer...